Full name : Horak Martin
First name : Martin
Mail : Institute of Physiology, Academy of Sciences of the Czech Republic v.v.i., Videnska 1083, 14220 Prague 4
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Country : Czech Republic
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| Title : Prophylaxis by a reversible cholinesterase inhibitor and the treatment NMDA receptor antagonists as combinatorial countermeasure against nerve agent poisoning in mice model - Kassa_2025_Chem.Biol.Interact__111386 |
| Author(s) : Kassa J , Konecny J , Svobodova B , Horak M , Korabecny J , Soukup O |
| Ref : Chemico-Biological Interactions , :111386 , 2025 |
| Abstract : |
| PubMedSearch : Kassa_2025_Chem.Biol.Interact__111386 |
| PubMedID: 39805415 |
| Title : Dizocilpine derivatives as neuroprotective NMDA receptor antagonists without psychomimetic side effects - Konecny_2024_Eur.J.Med.Chem_280_116981 |
| Author(s) : Konecny J , Misiachna A , Chvojkova M , Kleteckova L , Kolcheva M , Novak M , Prchal L , Ladislav M , Hemelikova K , Netolicky J , Hrabinova M , Kobrlova T , Karasova JZ , Pejchal J , Fibigar J , Vecera Z , Kucera T , Jendelova P , Zahumenska P , Langore E , Doderovic J , Pang YP , Vales K , Korabecny J , Soukup O , Horak M |
| Ref : Eur Journal of Medicinal Chemistry , 280 :116981 , 2024 |
| Abstract : |
| PubMedSearch : Konecny_2024_Eur.J.Med.Chem_280_116981 |
| PubMedID: 39442339 |
| Title : Morphing cholinesterase inhibitor amiridine into multipotent drugs for the treatment of Alzheimer's disease - Mezeiova_2024_Biomed.Pharmacother_173_116399 |
| Author(s) : Mezeiova E , Prchal L , Hrabinova M , Muckova L , Pulkrabkova L , Soukup O , Misiachna A , Janousek J , Fibigar J , Kucera T , Horak M , Makhaeva GF , Korabecny J |
| Ref : Biomed Pharmacother , 173 :116399 , 2024 |
| Abstract : |
| PubMedSearch : Mezeiova_2024_Biomed.Pharmacother_173_116399 |
| PubMedID: 38492439 |
| Title : Pro-cognitive effects of dual tacrine derivatives acting as cholinesterase inhibitors and NMDA receptor antagonists - Chvojkova_2024_Biomed.Pharmacother_176_116821 |
| Author(s) : Chvojkova M , Kolar D , Kovacova K , Cejkova L , Misiachna A , Hakenova K , Gorecki L , Horak M , Korabecny J , Soukup O , Vales K |
| Ref : Biomed Pharmacother , 176 :116821 , 2024 |
| Abstract : |
| PubMedSearch : Chvojkova_2024_Biomed.Pharmacother_176_116821 |
| PubMedID: 38823278 |
| Title : Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition - Misiachna_2024_Eur.J.Med.Chem_266_116130 |
| Author(s) : Misiachna A , Svobodova B , Netolicky J , Chvojkova M , Kleteckova L , Prchal L , Novak M , Hrabinova M , Kucera T , Muckova L , Moravcova Z , Karasova JZ , Pejchal J , Blazek F , Malinak D , Hakenova K , Krausova BH , Kolcheva M , Ladislav M , Korabecny J , Pahnke J , Vales K , Horak M , Soukup O |
| Ref : Eur Journal of Medicinal Chemistry , 266 :116130 , 2024 |
| Abstract : |
| PubMedSearch : Misiachna_2024_Eur.J.Med.Chem_266_116130 |
| PubMedID: 38218127 |
| Title : Structure-Guided Design of N-Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease - Svobodova_2023_Int.J.Mol.Sci_24_ |
| Author(s) : Svobodova B , Pulkrabkova L , Panek D , Misiachna A , Kolcheva M , Andrys R , Handl J , Capek J , Nyvltova P , Rousar T , Prchal L , Hepnarova V , Hrabinova M , Muckova L , Tosnerova D , Karabanovich G , Finger V , Soukup O , Horak M , Korabecny J |
| Ref : Int J Mol Sci , 24 : , 2023 |
| Abstract : |
| PubMedSearch : Svobodova_2023_Int.J.Mol.Sci_24_ |
| PubMedID: 37298087 |
| Title : 7-phenoxytacrine is a dually acting drug with neuroprotective efficacy in vivo - Kaniakova_2021_Biochem.Pharmacol__114460 |
| Author(s) : Kaniakova M , Korabecny J , Holubova K , Kleteckova L , Chvojkova M , Hakenova K , Prchal L , Novak M , Dolezal R , Hepnarova V , Svobodova B , Kucera T , Lichnerova K , Krausova B , Horak M , Vales K , Soukup O |
| Ref : Biochemical Pharmacology , :114460 , 2021 |
| Abstract : |
| PubMedSearch : Kaniakova_2021_Biochem.Pharmacol__114460 |
| PubMedID: 33571502 |
| Title : Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors - Gorecki_2021_Eur.J.Med.Chem_219_113434 |
| Author(s) : Gorecki L , Misiachna A , Damborsky J , Dolezal R , Korabecny J , Cejkova L , Hakenova K , Chvojkova M , Karasova JZ , Prchal L , Novak M , Kolcheva M , Kortus S , Vales K , Horak M , Soukup O |
| Ref : Eur Journal of Medicinal Chemistry , 219 :113434 , 2021 |
| Abstract : |
| PubMedSearch : Gorecki_2021_Eur.J.Med.Chem_219_113434 |
| PubMedID: 33892271 |
| Title : Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-d-Aspartate Receptor Antagonists - Konecny_2020_Biomolecules_11_ |
| Author(s) : Konecny J , Misiachna A , Hrabinova M , Pulkrabkova L , Benkova M , Prchal L , Kucera T , Kobrlova T , Finger V , Kolcheva M , Kortus S , Jun D , Valko M , Horak M , Soukup O , Korabecny J |
| Ref : Biomolecules , 11 : , 2020 |
| Abstract : |
| PubMedSearch : Konecny_2020_Biomolecules_11_ |
| PubMedID: 33375115 |
| Title : Combination of Memantine and 6-Chlorotacrine as Novel Multi-Target Compound against Alzheimer's Disease - Kaniakova_2019_Curr.Alzheimer.Res_16_821 |
| Author(s) : Kaniakova M , Nepovimova E , Kleteckova L , Skrenkova K , Holubova K , Chrienova Z , Hepnarova V , Kucera T , Kobrlova T , Vales K , Korabecny J , Soukup O , Horak M |
| Ref : Curr Alzheimer Res , 16 :821 , 2019 |
| Abstract : |
| PubMedSearch : Kaniakova_2019_Curr.Alzheimer.Res_16_821 |
| PubMedID: 30819076 |
| Title : The pharmacology of tacrine at N-methyl-d-aspartate receptors - Horak_2017_Prog.Neuropsychopharmacol.Biol.Psychiatry_75_54 |
| Author(s) : Horak M , Holubova K , Nepovimova E , Krusek J , Kaniakova M , Korabecny J , Vyklicky L , Kuca K , Stuchlik A , Ricny J , Vales K , Soukup O |
| Ref : Prog Neuropsychopharmacol Biological Psychiatry , 75 :54 , 2017 |
| Abstract : |
| PubMedSearch : Horak_2017_Prog.Neuropsychopharmacol.Biol.Psychiatry_75_54 |
| PubMedID: 28089695 |
| Title : Multi-target-directed therapeutic potential of 7-methoxytacrine-adamantylamine heterodimers in the Alzheimer's disease treatment - Gazova_2017_Biochim.Biophys.Acta.Mol.Basis.Dis_1863_607 |
| Author(s) : Gazova Z , Soukup O , Sepsova V , Siposova K , Drtinova L , Jost P , Spilovska K , Korabecny J , Nepovimova E , Fedunova D , Horak M , Kaniakova M , Wang ZJ , Hamouda AK , Kuca K |
| Ref : Biochimica & Biophysica Acta Mol Basis Dis , 1863 :607 , 2017 |
| Abstract : |
| PubMedSearch : Gazova_2017_Biochim.Biophys.Acta.Mol.Basis.Dis_1863_607 |
| PubMedID: 27865910 |