Full name : Svobodova Barbora
First name : Barbora
Mail : Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska 1083, Prague
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Country : Czech Republic
Email : barbora.svobodova@biomed.cas.cz
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Comment
| Title : Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition - Misiachna_2024_Eur.J.Med.Chem_266_116130 |
| Author(s) : Misiachna A , Svobodova B , Netolicky J , Chvojkova M , Kleteckova L , Prchal L , Novak M , Hrabinova M , Kucera T , Muckova L , Moravcova Z , Karasova JZ , Pejchal J , Blazek F , Malinak D , Hakenova K , Krausova BH , Kolcheva M , Ladislav M , Korabecny J , Pahnke J , Vales K , Horak M , Soukup O |
| Ref : Eur Journal of Medicinal Chemistry , 266 :116130 , 2024 |
| Abstract : |
| PubMedSearch : Misiachna_2024_Eur.J.Med.Chem_266_116130 |
| PubMedID: 38218127 |
| Title : Tacrine First-Phase Biotransformation and Associated Hepatotoxicity: A Possible Way to Avoid Quinone Methide Formation - Novak_2023_ACS.Chem.Biol_18_1993 |
| Author(s) : Novak M , Vajrychova M , Koutsilieri S , Sismanoglou DC , Kobrlova T , Prchal L , Svobodova B , Korabecny J , Zarybnicky T , Raisova-Stuchlikova L , Skalova L , Lauschke VM , Kucera R , Soukup O |
| Ref : ACS Chemical Biology , 18 :1993 , 2023 |
| Abstract : |
| PubMedSearch : Novak_2023_ACS.Chem.Biol_18_1993 |
| PubMedID: 37622522 |
| Title : UHPLC-Orbitrap study of the first phase tacrine in vitro metabolites and related Alzheimer's drug candidates using human liver microsomes - Novak_2023_J.Pharm.Biomed.Anal_224_115154 |
| Author(s) : Novak M , Svobodova B , Konecny J , Kuratkova A , Nevosadova L , Prchal L , Korabecny J , Lauschke VM , Soukup O , Kucera R |
| Ref : J Pharm Biomed Anal , 224 :115154 , 2023 |
| Abstract : |
| PubMedSearch : Novak_2023_J.Pharm.Biomed.Anal_224_115154 |
| PubMedID: 36442458 |
| Title : Structure-Guided Design of N-Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease - Svobodova_2023_Int.J.Mol.Sci_24_ |
| Author(s) : Svobodova B , Pulkrabkova L , Panek D , Misiachna A , Kolcheva M , Andrys R , Handl J , Capek J , Nyvltova P , Rousar T , Prchal L , Hepnarova V , Hrabinova M , Muckova L , Tosnerova D , Karabanovich G , Finger V , Soukup O , Horak M , Korabecny J |
| Ref : Int J Mol Sci , 24 : , 2023 |
| Abstract : |
| PubMedSearch : Svobodova_2023_Int.J.Mol.Sci_24_ |
| PubMedID: 37298087 |
| Title : Neurotoxicity evoked by organophosphates and available countermeasures - Pulkrabkova_2022_Arch.Toxicol__ |
| Author(s) : Pulkrabkova L , Svobodova B , Konecny J , Kobrlova T , Muckova L , Janousek J , Pejchal J , Korabecny J , Soukup O |
| Ref : Archives of Toxicology , : , 2022 |
| Abstract : |
| PubMedSearch : Pulkrabkova_2022_Arch.Toxicol__ |
| PubMedID: 36335468 |
| Title : 7-phenoxytacrine is a dually acting drug with neuroprotective efficacy in vivo - Kaniakova_2021_Biochem.Pharmacol__114460 |
| Author(s) : Kaniakova M , Korabecny J , Holubova K , Kleteckova L , Chvojkova M , Hakenova K , Prchal L , Novak M , Dolezal R , Hepnarova V , Svobodova B , Kucera T , Lichnerova K , Krausova B , Horak M , Vales K , Soukup O |
| Ref : Biochemical Pharmacology , :114460 , 2021 |
| Abstract : |
| PubMedSearch : Kaniakova_2021_Biochem.Pharmacol__114460 |
| PubMedID: 33571502 |
| Title : Cysteine-Targeted Insecticides against A. gambiae Acetylcholinesterase Are Neither Selective nor Reversible Inhibitors - Gorecki_2020_ACS.Med.Chem.Lett_11_65 |
| Author(s) : Gorecki L , Andrys R , Schmidt M , Kucera T , Psotka M , Svobodova B , Hrabcova V , Hepnarova V , Bzonek P , Jun D , Kuca K , Korabecny J , Musilek K |
| Ref : ACS Med Chem Lett , 11 :65 , 2020 |
| Abstract : |
| PubMedSearch : Gorecki_2020_ACS.Med.Chem.Lett_11_65 |
| PubMedID: 31938465 |
| Title : Exploring Structure-Activity Relationship in Tacrine-Squaramide Derivatives as Potent Cholinesterase Inhibitors - Svobodova_2019_Biomolecules_9_ |
| Author(s) : Svobodova B , Mezeiova E , Hepnarova V , Hrabinova M , Muckova L , Kobrlova T , Jun D , Soukup O , Jimeno ML , Marco-Contelles J , Korabecny J |
| Ref : Biomolecules , 9 : , 2019 |
| Abstract : |
| PubMedSearch : Svobodova_2019_Biomolecules_9_ |
| PubMedID: 31430943 |
| Title : A green tea polyphenol epigallocatechin-3-gallate enhances neuroregeneration after spinal cord injury by altering levels of inflammatory cytokines - Machova_2017_Neuropharmacol_126_213 |
| Author(s) : Machova Urdzikova L , Ruzicka J , Karova K , Kloudova A , Svobodova B , Amin A , Dubisova J , Schmidt M , Kubinova S , Jhanwar-Uniyal M , Jendelova P |
| Ref : Neuropharmacology , 126 :213 , 2017 |
| Abstract : |
| PubMedSearch : Machova_2017_Neuropharmacol_126_213 |
| PubMedID: 28899730 |