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| Title : Engineered alpha4beta2 nicotinic acetylcholine receptors as models for measuring agonist binding and effect at the orthosteric low-affinity alpha4-alpha4 interface - Ahring_2015_Neuropharmacol_92_135 |
| Author(s) : Ahring PK , Olsen JA , Nielsen EO , Peters D , Pedersen MH , Rohde LA , Kastrup JS , Shahsavar A , Indurthi DC , Chebib M , Gajhede M , Balle T |
| Ref : Neuropharmacology , 92 :135 , 2015 |
| Abstract : Ahring_2015_Neuropharmacol_92_135 |
| ESTHER : Ahring_2015_Neuropharmacol_92_135 |
| PubMedSearch : Ahring_2015_Neuropharmacol_92_135 |
| PubMedID: 25595102 |
| Title : Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors - Harpsoe_2013_J.Biol.Chem_288_2559 |
| Author(s) : Harpsoe K , Hald H , Timmermann DB , Jensen ML , Dyhring T , Nielsen EO , Peters D , Balle T , Gajhede M , Kastrup JS , Ahring PK |
| Ref : Journal of Biological Chemistry , 288 :2559 , 2013 |
| Abstract : Harpsoe_2013_J.Biol.Chem_288_2559 |
| ESTHER : Harpsoe_2013_J.Biol.Chem_288_2559 |
| PubMedSearch : Harpsoe_2013_J.Biol.Chem_288_2559 |
| PubMedID: 23229547 |
| Title : Synthesis, pharmacology, and biostructural characterization of novel alpha4beta2 nicotinic acetylcholine receptor agonists - Ussing_2013_J.Med.Chem_56_940 |
| Author(s) : Ussing CA , Hansen CP , Petersen JG , Jensen AA , Rohde LA , Ahring PK , Nielsen EO , Kastrup JS , Gajhede M , Frolund B , Balle T |
| Ref : Journal of Medicinal Chemistry , 56 :940 , 2013 |
| Abstract : Ussing_2013_J.Med.Chem_56_940 |
| ESTHER : Ussing_2013_J.Med.Chem_56_940 |
| PubMedSearch : Ussing_2013_J.Med.Chem_56_940 |
| PubMedID: 23256554 |
| Title : Positive allosteric modulation of alpha4beta2 nAChR agonist induced behaviour - Rode_2012_Brain.Res_1458_67 |
| Author(s) : Rode F , Munro G , Holst D , Nielsen EO , Troelsen KB , Timmermann DB , Ronn LC , Grunnet M |
| Ref : Brain Research , 1458 :67 , 2012 |
| Abstract : Rode_2012_Brain.Res_1458_67 |
| ESTHER : Rode_2012_Brain.Res_1458_67 |
| PubMedSearch : Rode_2012_Brain.Res_1458_67 |
| PubMedID: 22552114 |
| Title : Augmentation of cognitive function by NS9283, a stoichiometry-dependent positive allosteric modulator of alpha2- and alpha4-containing nicotinic acetylcholine receptors - Timmermann_2012_Br.J.Pharmacol_167_164 |
| Author(s) : Timmermann DB , Sandager-Nielsen K , Dyhring T , Smith M , Jacobsen AM , Nielsen EO , Grunnet M , Christensen JK , Peters D , Kohlhaas KL , Olsen GM , Ahring PK |
| Ref : British Journal of Pharmacology , 167 :164 , 2012 |
| Abstract : Timmermann_2012_Br.J.Pharmacol_167_164 |
| ESTHER : Timmermann_2012_Br.J.Pharmacol_167_164 |
| PubMedSearch : Timmermann_2012_Br.J.Pharmacol_167_164 |
| PubMedID: 22506660 |
| Title : Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha4beta2 receptors: unique role of halogen bonding revealed - Rohde_2012_J.Biol.Chem_287_4248 |
| Author(s) : Rohde LA , Ahring PK , Jensen ML , Nielsen EO , Peters D , Helgstrand C , Krintel C , Harpsoe K , Gajhede M , Kastrup JS , Balle T |
| Ref : Journal of Biological Chemistry , 287 :4248 , 2012 |
| Abstract : Rohde_2012_J.Biol.Chem_287_4248 |
| ESTHER : Rohde_2012_J.Biol.Chem_287_4248 |
| PubMedSearch : Rohde_2012_J.Biol.Chem_287_4248 |
| PubMedID: 22170047 |
| Title : Crystal structure of Lymnaea stagnalis AChBP complexed with the potent nAChR antagonist DHbetaE suggests a unique mode of antagonism - Shahsavar_2012_PLoS.One_7_e40757 |
| Author(s) : Shahsavar A , Kastrup JS , Nielsen EO , Kristensen JL , Gajhede M , Balle T |
| Ref : PLoS ONE , 7 :e40757 , 2012 |
| Abstract : Shahsavar_2012_PLoS.One_7_e40757 |
| ESTHER : Shahsavar_2012_PLoS.One_7_e40757 |
| PubMedSearch : Shahsavar_2012_PLoS.One_7_e40757 |
| PubMedID: 22927902 |
| Title : 11C-NS14492 as a novel PET radioligand for imaging cerebral alpha7 nicotinic acetylcholine receptors: in vivo evaluation and drug occupancy measurements - Ettrup_2011_J.Nucl.Med_52_1449 |
| Author(s) : Ettrup A , Mikkelsen JD , Lehel S , Madsen J , Nielsen EO , Palner M , Timmermann DB , Peters D , Knudsen GM |
| Ref : J Nucl Med , 52 :1449 , 2011 |
| Abstract : Ettrup_2011_J.Nucl.Med_52_1449 |
| ESTHER : Ettrup_2011_J.Nucl.Med_52_1449 |
| PubMedSearch : Ettrup_2011_J.Nucl.Med_52_1449 |
| PubMedID: 21828113 |
| Title : In vitro pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107 - Malysz_2010_J.Pharmacol.Exp.Ther_334_863 |
| Author(s) : Malysz J , Anderson DJ , Gronlien JH , Ji J , Bunnelle WH , Hakerud M , Thorin-Hagene K , Ween H , Helfrich R , Hu M , Gubbins E , Gopalakrishnan S , Puttfarcken PS , Briggs CA , Li J , Meyer MD , Dyhring T , Ahring PK , Nielsen EO , Peters D , Timmermann DB , Gopalakrishnan M |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 334 :863 , 2010 |
| Abstract : Malysz_2010_J.Pharmacol.Exp.Ther_334_863 |
| ESTHER : Malysz_2010_J.Pharmacol.Exp.Ther_334_863 |
| PubMedSearch : Malysz_2010_J.Pharmacol.Exp.Ther_334_863 |
| PubMedID: 20504915 |
| Title : Alpha7 nicotinic acetylcholine receptor activation ameliorates scopolamine-induced behavioural changes in a modified continuous Y-maze task in mice - Redrobe_2009_Eur.J.Pharmacol_602_58 |
| Author(s) : Redrobe JP , Nielsen EO , Christensen JK , Peters D , Timmermann DB , Olsen GM |
| Ref : European Journal of Pharmacology , 602 :58 , 2009 |
| Abstract : Redrobe_2009_Eur.J.Pharmacol_602_58 |
| ESTHER : Redrobe_2009_Eur.J.Pharmacol_602_58 |
| PubMedSearch : Redrobe_2009_Eur.J.Pharmacol_602_58 |
| PubMedID: 18848931 |
| Title : Molecular imaging of alpha7 nicotinic acetylcholine receptors: design and evaluation of the potent radioligand [18F]NS10743 - Deuther-Conrad_2009_Eur.J.Nucl.Med.Mol.Imaging_36_791 |
| Author(s) : Deuther-Conrad W , Fischer S , Hiller A , Nielsen EO , Timmermann DB , Steinbach J , Sabri O , Peters D , Brust P |
| Ref : Eur J Nucl Med Mol Imaging , 36 :791 , 2009 |
| Abstract : Deuther-Conrad_2009_Eur.J.Nucl.Med.Mol.Imaging_36_791 |
| ESTHER : Deuther-Conrad_2009_Eur.J.Nucl.Med.Mol.Imaging_36_791 |
| PubMedSearch : Deuther-Conrad_2009_Eur.J.Nucl.Med.Mol.Imaging_36_791 |
| PubMedID: 19137292 |
| Title : An allosteric modulator of the alpha7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo - Timmermann_2007_J.Pharmacol.Exp.Ther_323_294 |
| Author(s) : Timmermann DB , Gronlien JH , Kohlhaas KL , Nielsen EO , Dam E , Jorgensen TD , Ahring PK , Peters D , Holst D , Christensen JK , Malysz J , Briggs CA , Gopalakrishnan M , Olsen GM |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 323 :294 , 2007 |
| Abstract : Timmermann_2007_J.Pharmacol.Exp.Ther_323_294 |
| ESTHER : Timmermann_2007_J.Pharmacol.Exp.Ther_323_294 |
| PubMedSearch : Timmermann_2007_J.Pharmacol.Exp.Ther_323_294 |
| PubMedID: 17625074 |
| Title : New ligands with affinity for the alpha4beta2 subtype of nicotinic acetylcholine receptors. Synthesis, receptor binding, and 3D-QSAR modeling - Audouze_2006_J.Med.Chem_49_3159 |
| Author(s) : Audouze K , Nielsen EO , Olsen GM , Ahring P , Jorgensen TD , Peters D , Liljefors T , Balle T |
| Ref : Journal of Medicinal Chemistry , 49 :3159 , 2006 |
| Abstract : Audouze_2006_J.Med.Chem_49_3159 |
| ESTHER : Audouze_2006_J.Med.Chem_49_3159 |
| PubMedSearch : Audouze_2006_J.Med.Chem_49_3159 |
| PubMedID: 16722635 |