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Family Report for: ACHE


Family ACHE
Block C
Parent Family : Cholinesterase


Acetylcholinesterase (ACHE; EC controls synaptic and neurohumoral cholinergic activity by hydrolyzing the neurotransmitter acetylcholine. ACHE function relies on precise regulation of its expression and localization. In particular, alternative splicing of the 3-prime region of ACHE results in ACHE isoforms with distinct C-terminal peptides that determine posttranslational maturation and oligomeric assembly. Acetylcholinesterase is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen.

1 Xenobiotic(s) sensitivity

Interpro : IPR000997 (Cholinesterase), IPR002018 (Carboxylesterase, type B)
PFam : PF00135 (COesterase), PF08674 (AChE_tetra)
Prints : PR00878
EC at KEGG :
Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin : Text only/graphic display
Seed alignment with MAFFT : No colour/coloured with Mview
Alignment with MAFFT : No colour/coloured with Mview
Dendrogram : Graphical display, obtained with the dnd file produced by Clustalw
HMM profile : HMM profile

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Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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