biooc-ZHD101
Bionectria ochroleuca (Gliocladium roseum), Clonostachys rosea f. rosea, zearalenone hydrolase ZHD101 ZEN-JJM
Comment
Relationship
Family : Zearalenone-hydrolase
Block : X
Position in NCBI Life Tree : Bionectria ochroleuca
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Fungi N E > Dikarya N E > Ascomycota N E > saccharomyceta N E > Pezizomycotina N E > leotiomyceta N E > sordariomyceta N E > Sordariomycetes N E > Hypocreomycetidae N E > Hypocreales N E > Bionectriaceae N E > Clonostachys N E > Clonostachys rosea N EMolecular evidence
No mutation
3WZL - Crystal structure of the mycoestrogen-detoxifying lactonase ZHD (ZEN lactonase) from Clonostachys rosea
3WZM - Crystal structure of the mycoestrogen-detoxifying lactonase ZHD (ZEN lactonase mutant complex) from Clonostachys rosea
5C7Y - Clonostachys rosea (fungus) ZHD-Intermediate complex after ZHD crystal soaking in ZEN for 9min
5C81 - Clonostachys rosea (fungus) ZHD-Intermediate complex after ZHD crystal soaking in ZEN for 12min
5C8X - Clonostachys rosea (fungus) ZHD-Intermediate complex after ZHD crystal soaking in ZEN for 20min
5C8Z - Clonostachys rosea (fungus) ZHD-ZGR complex after ZHD crystal soaking in ZEN for 30min || Clonostachys rosea (fungus) Lactonohydrolase zearalenone hydrolase ZHD-ZGR complex after ZHD crystal soaking in ZEN (mycoestrogen-detoxifying lactonase ZEN lactonase) for 30min
5IE4 - Crystal structure of a Clonostachys rosea (fungus) lactonase mutant in complex with substrate a
5IE5 - Crystal structure of a Clonostachys rosea (fungus) lactonase double mutant in complex with substrate a
5IE6 - Crystal structure of a Clonostachys rosea (fungus) lactonase mutant in complex with substrate b
5IE7 - Crystal structure of a Clonostachys rosea lactonase double mutant in complex with substrate b
5XMW - Clonostachys rosea (fungus) Lactonohydrolase zearalenone hydrolase Selenomethionine-derivated ZHD
6JQZ - Crystal structure of the mycoestrogen-detoxifying lactonase ZHD. ZHD\/H242A complex with ZEN from Clonostachys rosea
6JR2 - Crystal structure of the mycoestrogen-detoxifying lactonase ZHD. ZHD\/H242A complex with alpha-ZOL from Clonostachys rosea
6JR5 - Crystal structure of the mycoestrogen-detoxifying lactonase ZHD. ZHD\/H242A complex with beta-ZOL from Clonostachys rosea
6JR9 - Crystal structure of the mycoestrogen-detoxifying lactonase ZHD. ZHD\/W183F complex with ZEN from Clonostachys rosea
6JRA - Crystal structure of the mycoestrogen-detoxifying lactonase ZHD. ZHD\/W183F complex with alpha-ZOL from Clonostachys rosea
6JRB - Crystal structure of the mycoestrogen-detoxifying lactonase ZHD. ZHD\/W183F complex with beta-ZOL from Clonostachys rosea
6JRC - Crystal structure of the mycoestrogen-detoxifying lactonase ZHD. ZHD complex with alpha-ZOL from Clonostachys rosea
6JRD - Crystal structure of the mycoestrogen-detoxifying lactonase ZHD. ZHD complex with beta-ZOL from Clonostachys rosea
No kinetic
No disease
Database
Sequence
Peptide
MRTRSTISTP NGITWYYEQE GTGPDIVLVP DGLGECQMFD SSVSQIAAQG FRVTTFDMPG MSRSAKAPAE TYTEVTAQKL ASYVISILDA LDIKHATVWG CSSGASTVVA LLLGYPDRIR NAMCHELPTK LLDHLSNTAV LEDEEISNIL ANVMLNDVSG GSEAWQALGV EVHARLHKNY PVWARGYPRT IPPSAPVQDV EALRGKPLDW TVGAATPTES FFDNIVTATK AGVNIGLLPG MHFPYVSHPD VFAKYVVETT QKHL
References (23)
| Title : [Structure-guided engineering for improving the thermal stability of zearalenone hydrolase] - Guan_2023_Sheng.Wu.Gong.Cheng.Xue.Bao_39_3336 |
| Author(s) : Guan A , Zhang M , Xu F |
| Ref : Sheng Wu Gong Cheng Xue Bao , 39 :3336 , 2023 |
| Abstract : |
| PubMedSearch : Guan_2023_Sheng.Wu.Gong.Cheng.Xue.Bao_39_3336 |
| PubMedID: 37622364 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Metabolism of Zearalenone in the Rumen of Dairy Cows with and without Application of a Zearalenone-Degrading Enzyme - Gruber-Dorninger_2021_Toxins.(Basel)_13_ |
| Author(s) : Gruber-Dorninger C , Faas J , Doupovec B , Aleschko M , Stoiber C , Hobartner-Gussl A , Schondorfer K , Killinger M , Zebeli Q , Schatzmayr D |
| Ref : Toxins (Basel) , 13 : , 2021 |
| Abstract : |
| PubMedSearch : Gruber-Dorninger_2021_Toxins.(Basel)_13_ |
| PubMedID: 33499402 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Identification of a Potent Enzyme for the Detoxification of Zearalenone - Zhang_2020_J.Agric.Food.Chem_68_376 |
| Author(s) : Zhang Z , Xu W , Wu H , Zhang W , Mu W |
| Ref : Journal of Agricultural and Food Chemistry , 68 :376 , 2020 |
| Abstract : |
| PubMedSearch : Zhang_2020_J.Agric.Food.Chem_68_376 |
| PubMedID: 31816236 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : The Trp183 is essential in lactonohydrolase ZHD detoxifying zearalenone and zearalenols - Zhou_2020_Biochem.Biophys.Res.Commun_522_986 |
| Author(s) : Zhou H , Li L , Zhan B , Wang S , Li J , Hu XJ |
| Ref : Biochemical & Biophysical Research Communications , 522 :986 , 2020 |
| Abstract : |
| PubMedSearch : Zhou_2020_Biochem.Biophys.Res.Commun_522_986 |
| PubMedID: 31810602 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Theoretical Study on Zearalenol Compounds Binding with Wild Type Zearalenone Hydrolase and V153H Mutant - Liu_2018_Int.J.Mol.Sci_19_ |
| Author(s) : Liu Y , Wan Y , Zhu J , Yu Z , Tian X , Han J , Zhang Z , Han W |
| Ref : Int J Mol Sci , 19 : , 2018 |
| Abstract : |
| PubMedSearch : Liu_2018_Int.J.Mol.Sci_19_ |
| PubMedID: 30231501 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Efficient elimination of zearalenone at high processing temperatures by a robust mutant of Gliocladium roseum zearalenone lactonase - Fang_2022_Food.Control_142_109222 |
| Author(s) : Fang Y , Huang Z , Xu W , Wang C , Sun Y , Zhang W , Guang C , Mu W |
| Ref : Food Control , 132 :109222 , 2017 |
| Abstract : |
| PubMedSearch : Fang_2022_Food.Control_142_109222 |
| PubMedID: |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : The structure of a complex of the lactonohydrolase zearalenone hydrolase with the hydrolysis product of zearalenone at 1.60 A resolution - Qi_2017_Acta.Crystallogr.F.Struct.Biol.Commun_73_376 |
| Author(s) : Qi Q , Yang WJ , Zhou HJ , Ming DM , Sun KL , Xu TY , Hu XJ , Lv H |
| Ref : Acta Crystallographica F Struct Biol Commun , 73 :376 , 2017 |
| Abstract : |
| PubMedSearch : Qi_2017_Acta.Crystallogr.F.Struct.Biol.Commun_73_376 |
| PubMedID: 28695844 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : High-level expression of a ZEN-detoxifying gene by codon optimization and biobrick in Pichia pastoris - Xiang_2016_Microbiol.Res_193_48 |
| Author(s) : Xiang L , Wang Q , Zhou Y , Yin L , Zhang G , Ma Y |
| Ref : Microbiol Res , 193 :48 , 2016 |
| Abstract : |
| PubMedSearch : Xiang_2016_Microbiol.Res_193_48 |
| PubMedID: 27825486 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Isolation and characterisation of enzymatic zearalenone hydrolysis reaction products - Vekiru_2016_World.Mycotoxin.J_9_353 |
| Author(s) : Vekiru E , Fruhauf S , Hametner C , Schatzmayr G , Krska R , Moll WD , Schuhmacher R |
| Ref : World Mycotoxin Journal , 9 :353 , 2016 |
| Abstract : |
| PubMedSearch : Vekiru_2016_World.Mycotoxin.J_9_353 |
| PubMedID: |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Enhanced alpha-Zearalenol Hydrolyzing Activity of a Mycoestrogen-Detoxifying Lactonase by Structure-Based Engineering - Xu_2016_ACS.Catal_6_7657 |
| Author(s) : Xu Z , Liu W , Chen CC , Li Q , Huang JW , Ko TP , Liu G , Peng W , Cheng YS , Chen Y , Jin J , Li H , Zheng Y , Guo RT |
| Ref : ACS Catal , 6 :7657 , 2016 |
| Abstract : |
| PubMedSearch : Xu_2016_ACS.Catal_6_7657 |
| PubMedID: |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Crystal structure and substrate-binding mode of the mycoestrogen-detoxifying lactonase ZHD from Clonostachys rosea - Peng_2014_RSC.Adv_4_62321 |
| Author(s) : Peng W , Ko TP , Yang YY , Zheng YY , Chen CC , Zhu Z , Huang CH , Zeng YF , Huang JW , Wang AHJ , Liu JR , Guo RT |
| Ref : RSC Advances , 4 :62321 , 2014 |
| Abstract : |
| PubMedSearch : Peng_2014_RSC.Adv_4_62321 |
| PubMedID: |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Zearalenone lactonohydrolase activity in Hypocreales and its evolutionary relationships within the epoxide hydrolase subset of a\/b-hydrolases - Popiel_2014_BMC.Microbiol_14_82 |
| Author(s) : Popiel D , Koczyk G , Dawidziuk A , Gromadzka K , Blaszczyk L , Chelkowski J |
| Ref : BMC Microbiol , 14 :82 , 2014 |
| Abstract : |
| PubMedSearch : Popiel_2014_BMC.Microbiol_14_82 |
| PubMedID: 24708405 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Zearalenone detoxification by zearalenone hydrolase is important for the antagonistic ability of Clonostachys rosea against mycotoxigenic Fusarium graminearum - Kosawang_2014_Fungal.Biol_118_364 |
| Author(s) : Kosawang C , Karlsson M , Velez H , Rasmussen PH , Collinge DB , Jensen B , Jensen DF |
| Ref : Fungal Biol , 118 :364 , 2014 |
| Abstract : |
| PubMedSearch : Kosawang_2014_Fungal.Biol_118_364 |
| PubMedID: 24742831 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Construction of an ZEN-jjm expressing vector and its expression in Pichia pastoris. - Tan_2010_Zhongguo.Wei.Sheng.Tai.Xue.Za.Zhi_22_1061 |
| Author(s) : Tan QL , Xu F , Li P , Cheng BC , Luo J , Wei H |
| Ref : Zhongguo Wei Sheng Tai Xue Za Zhi , 22 :1061 , 2010 |
| Abstract : |
| PubMedSearch : Tan_2010_Zhongguo.Wei.Sheng.Tai.Xue.Za.Zhi_22_1061 |
| PubMedID: |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Reduced contamination by the Fusarium mycotoxin zearalenone in maize kernels through genetic modification with a detoxification gene - Igawa_2007_Appl.Environ.Microbiol_73_1622 |
| Author(s) : Igawa T , Takahashi-Ando N , Ochiai N , Ohsato S , Shimizu T , Kudo T , Yamaguchi I , Kimura M |
| Ref : Applied Environmental Microbiology , 73 :1622 , 2007 |
| Abstract : |
| PubMedSearch : Igawa_2007_Appl.Environ.Microbiol_73_1622 |
| PubMedID: 17209063 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : A model transgenic cereal plant with detoxification activity for the estrogenic mycotoxin zearalenone - Higa-Nishiyama_2005_Transgenic.Res_14_713 |
| Author(s) : Higa-Nishiyama A , Takahashi-Ando N , Shimizu T , Kudo T , Yamaguchi I , Kimura M |
| Ref : Transgenic Res , 14 :713 , 2005 |
| Abstract : |
| PubMedSearch : Higa-Nishiyama_2005_Transgenic.Res_14_713 |
| PubMedID: 16245162 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Efficient decontamination of zearalenone, the mycotoxin of cereal pathogen, by transgenic yeasts through the expression of a synthetic lactonohydrolase gene - Takahashi-Ando_2005_Appl.Microbiol.Biotechnol_67_838 |
| Author(s) : Takahashi-Ando N , Tokai T , Hamamoto H , Yamaguchi I , Kimura M |
| Ref : Applied Microbiology & Biotechnology , 67 :838 , 2005 |
| Abstract : |
| PubMedSearch : Takahashi-Ando_2005_Appl.Microbiol.Biotechnol_67_838 |
| PubMedID: 15630583 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Metabolism of zearalenone by genetically modified organisms expressing the detoxification gene from Clonostachys rosea - Takahashi-Ando_2004_Appl.Environ.Microbiol_70_3239 |
| Author(s) : Takahashi-Ando N , Ohsato S , Shibata T , Hamamoto H , Yamaguchi I , Kimura M |
| Ref : Applied Environmental Microbiology , 70 :3239 , 2004 |
| Abstract : |
| PubMedSearch : Takahashi-Ando_2004_Appl.Environ.Microbiol_70_3239 |
| PubMedID: 15184117 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Expression in cereal plants of genes that inactivate Fusarium mycotoxins - Higa_2003_Biosci.Biotechnol.Biochem_67_914 |
| Author(s) : Higa A , Kimura M , Mimori K , Ochiai-Fukuda T , Tokai T , Takahashi-Ando N , Nishiuchi T , Igawa T , Fujimura M , Hamamoto H , Usami R , Yamaguchi I |
| Ref : Biosci Biotechnol Biochem , 67 :914 , 2003 |
| Abstract : |
| PubMedSearch : Higa_2003_Biosci.Biotechnol.Biochem_67_914 |
| PubMedID: 12784641 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Purification and characterization of a lactonase from Erwinia cypripedii 314B that hydrolyzes ( S)-5-oxo-2-tetrahydrofurancarboxylic acid - Mochizuki_2003_Arch.Microbiol_180_490 |
| Author(s) : Mochizuki K |
| Ref : Arch Microbiol , 180 :490 , 2003 |
| Abstract : |
| PubMedSearch : Mochizuki_2003_Arch.Microbiol_180_490 |
| PubMedID: 14576976 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : A novel lactonohydrolase responsible for the detoxification of zearalenone: enzyme purification and gene cloning - Takahashi-Ando_2002_Biochem.J_365_1 |
| Author(s) : Takahashi-Ando N , Kimura M , Kakeya H , Osada H , Yamaguchi I |
| Ref : Biochemical Journal , 365 :1 , 2002 |
| Abstract : |
| PubMedSearch : Takahashi-Ando_2002_Biochem.J_365_1 |
| PubMedID: 11978180 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Purification and characterization of a zearalenone degrading enzyme produced byGliocladium roseum - Matthies_2002_Mycotoxin.Res_18 Suppl 1_65 |
| Author(s) : Matthies I , Buchenauer H |
| Ref : Mycotoxin Res , 18 Suppl 1 :65 , 2002 |
| Abstract : |
| PubMedSearch : Matthies_2002_Mycotoxin.Res_18 Suppl 1_65 |
| PubMedID: 23606097 |
| Gene_locus related to this paper: biooc-ZHD101 |
| Title : Induction of a zearalenone degrading enzyme caused by the substrate and its derivatives - Matthies_2001_Mycotoxin.Res_17 Suppl 1_28 |
| Author(s) : Matthies I , Woerfel G , Karlovsky P |
| Ref : Mycotoxin Res , 17 Suppl 1 :28 , 2001 |
| Abstract : |
| PubMedSearch : Matthies_2001_Mycotoxin.Res_17 Suppl 1_28 |
| PubMedID: 23605754 |
| Gene_locus related to this paper: biooc-ZHD101 |