pseae-PA1510
Pseudomonas aeruginosa hypothetical protein pa1510 Tle4
Comment
The type VI lipase effectors Tle1-Tle5 secreted by the bacterial type VI secretion system (T6SS) have recently been identified as antibacterial effectors that hydrolyze membrane phospholipids. The Tle1-4 display phospholipase A1 and A2 (PLA1) (PLA2) activities. Tle1 belongs to Duf_2235 family and here Tle4 belongs to PGAP1. Other strains: Pseudomonas aeruginosa (strains ATCC 15692 \/ PAO1 \/ 1C \/ PRS 101 \/ LMG 12228\; 39016\; LESB58\; UCBPP-PA14\; C3719\; 2192). The structure 5H7Y (Structure of immunity protein TplEi of T6SS from Pseudomonas aeruginosa complexed with L peptide) contains only a small fragment of Tle4
Relationship
Family : PGAP1
Block : X
Position in NCBI Life Tree : Pseudomonas aeruginosa
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Bacteria N E > Proteobacteria N E > Gammaproteobacteria N E > Pseudomonadales N E > Pseudomonadaceae N E > Pseudomonas N E > Pseudomonas aeruginosa group N E > Pseudomonas aeruginosa N EMolecular evidence
Sequence
Peptide
MSSEPLEPNQ DVIIPRSRDS LGRPVYKAQL TRTDNQSEKV ALIRQTAPLP VIFIPGIMGT NLRNKADKSE VWRPPNGLWP MDDLFASIGA LWTWAWRGPK ARQELLKAEQ VEVDDQGTID VGQSGLSEEA ARLRGWGKVM RSAYNPVMGL MERRLDNIVS RRELQAWWND EALSPPGDQG EEQGKVGPID EEELLRASRY QFDVWCAGYN WLQSNRQSAL DVRDYIENTV LPFYQKECGL DPEQMRRMKV ILVTHSMGGL VARALTQLHG YERVLGVVHG VQPATGSSTI YHHMRCGYEG IAQVVLGRNA GEVTAIVANS AGALELAPSA EYREGRPWLF LCDAQGQVLK DIDGKPRAYP QNQDPYEEIY KNTTWYGLVP EQNSQYLDMS DKKEGLRVGP RDNFEDLIDS IANFHGELSA AGYHSETYAH YGADDSRHSW RDLIWKGDPT PLETPGATLN DDENGTYNSW FRRGLPTIVQ GPLETGNPLD ASGSGGDETV PTDSGQAPAL AGVKASFRHG SKGKGQANTK RGYEHQESYN DARAQWAALY GVIKITQLAD WHPNDKGGT
References (6)
| Title : The Pseudomonas aeruginosa Type VI Secretion PGAP1-like Effector Induces Host Autophagy by Activating Endoplasmic Reticulum Stress - Jiang_2016_Cell.Rep_16_1502 |
| Author(s) : Jiang F , Wang X , Wang B , Chen L , Zhao Z , Waterfield NR , Yang G , Jin Q |
| Ref : Cell Rep , 16 :1502 , 2016 |
| PubMedID: 27477276 |
| Gene_locus related to this paper: pseae-PA1510 |
| Title : The structural basis of the Tle4-Tli4 complex reveals the self-protection mechanism of H2-T6SS in Pseudomonas aeruginosa - Lu_2014_Acta.Crystallogr.D.Biol.Crystallogr_70_3233 |
| Author(s) : Lu D , Zheng Y , Liao N , Wei L , Xu B , Liu X , Liu J |
| Ref : Acta Crystallographica D Biol Crystallogr , 70 :3233 , 2014 |
| PubMedID: 25478841 |
| Gene_locus related to this paper: pseae-PA1510 |
| Title : Genetic characterization indicates that a specific subpopulation of Pseudomonas aeruginosa is associated with keratitis infections - Stewart_2011_J.Clin.Microbiol_49_993 |
| Author(s) : Stewart RM , Wiehlmann L , Ashelford KE , Preston SJ , Frimmersdorf E , Campbell BJ , Neal TJ , Hall N , Tuft S , Kaye SB , Winstanley C |
| Ref : J Clin Microbiol , 49 :993 , 2011 |
| PubMedID: 21227987 |
| Gene_locus related to this paper: pseae-a3kt39 , pseae-clipa , pseae-llipa , pseae-PA0201 , pseae-PA0231 , pseae-PA0308 , pseae-PA0368 , pseae-PA0480 , pseae-PA0543 , pseae-PA0599 , pseae-PA1166 , pseae-PA1239 , pseae-PA1304 , pseae-PA1510 , pseae-PA1558 , pseae-PA1597 , pseae-PA2098 , pseae-PA2302 , pseae-PA2425 , pseae-PA2540 , pseae-PA2682 , pseae-PA2927 , pseae-PA2949 , pseae-PA3301 , pseae-PA3327 , pseae-PA3695 , pseae-PA3859 , pseae-PA4968 , pseae-PA5080 , pseae-PCHC , pseae-PCHF , pseae-PHAC2 , pseae-phaD , pseae-Q8G8C7 , pseae-Q8G8T6 , pseae-q9i252 |