Gene_locus Report for: droer-b3n612 Drosophila erecta (Fruit fly) GG24195
Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Panarthropoda: N E > Arthropoda: N E > Mandibulata: N E > Pancrustacea: N E > Hexapoda: N E > Insecta: N E > Dicondylia: N E > Pterygota: N E > Neoptera: N E > Holometabola: N E > Diptera: N E > Brachycera: N E > Muscomorpha: N E > Eremoneura: N E > Cyclorrhapha: N E > Schizophora: N E > Acalyptratae: N E > Ephydroidea: N E > Drosophilidae: N E > Drosophilinae: N E > Drosophilini: N E > Drosophila [fruit fly, genus]: N E > Sophophora: N E > melanogaster group: N E > melanogaster subgroup: N E > Drosophila erecta: N E A85-EsteraseD-FGH :
droer-b3nz14 Drosophila erecta (Fruit fly) GG15619 .
ABHD18 :
droer-b3nct9 Drosophila erecta (Fruit fly) GG15592 .
abh_upf0017 :
droer-b3n7k8 Drosophila erecta (Fruit fly) GG23418 ,
droer-b3nar5 Drosophila erecta (Fruit fly) GG24924 .
ACHE :
droer-ACHE Drosophila erecta (Fruit fly) acetylcholinesterase GG17071 .
Acidic_Lipase :
droer-b3n5c7 Drosophila erecta (Fruit fly) Lipase ,
droer-b3n5d0 Drosophila erecta (Fruit fly) GG10374 ,
droer-b3n5d8 Drosophila erecta (Fruit fly) Lipase ,
droer-b3n5d9 Drosophila erecta (Fruit fly) Lipase ,
droer-b3n319 Drosophila erecta (Fruit fly) Lipase ,
droer-b3n547 Drosophila erecta (Fruit fly) GG10365 ,
droer-b3n549 Drosophila erecta (Fruit fly) Lipase ,
droer-b3n558 Drosophila erecta (Fruit fly) GG23662 ,
droer-b3n560 Drosophila erecta (Fruit fly) GG23660 ,
droer-b3nim7 Drosophila erecta (Fruit fly) Lipase ,
droer-b3nkn2 Drosophila erecta (Fruit fly) Lipase ,
droer-b3nqg9 Drosophila erecta (Fruit fly) Lipase ,
droer-b3nqm8 Drosophila erecta (Fruit fly) Lipase ,
droer-b3p6d4 Drosophila erecta (Fruit fly) Lipase ,
droer-b3p6d5 Drosophila erecta (Fruit fly) Lipase ,
droer-b3p152 Drosophila erecta (Fruit fly) Lipase ,
droer-b3p486 Drosophila erecta (Fruit fly) Lipase ,
droer-b3p487 Drosophila erecta (Fruit fly) Lipase ,
droer-b3p488 Drosophila erecta (Fruit fly) Lipase ,
droer-b3p489 Drosophila erecta (Fruit fly) Lipase .
Carb_B_Arthropoda :
droer-b3n8f7 Drosophila erecta (Fruit fly) GG10040 ,
droer-b3ne97 Drosophila erecta (Fruit fly) GG16191 ,
droer-b3nmh4 Drosophila erecta (Fruit fly) GG21053 ,
droer-b3nmy2 Drosophila erecta (Fruit fly) GG20762 ,
droer-b3nst4 Drosophila erecta (Fruit fly) GG18565 ,
droer-b3nyp5.1 Drosophila erecta (Fruit fly) GG25094 ,
droer-b3nyp5.2 Drosophila erecta (Fruit fly) GG25094 ,
droer-b3nyp6 Drosophila erecta (Fruit fly) GG25083 ,
droer-b3nyp7 Drosophila erecta (Fruit fly) GG25072 ,
droer-b3nyp8 Drosophila erecta (Fruit fly) GG14130 ,
droer-b3nyp9 Drosophila erecta (Fruit fly) GG25062 ,
droer-b3nzj0 Drosophila erecta (Fruit fly) GG17914 ,
droer-b3p2x6 Drosophila erecta (Fruit fly) GG25183 ,
droer-b3p2x7 Drosophila erecta (Fruit fly) GG25172 ,
droer-b3p2x9 Drosophila erecta (Fruit fly) GG25150 ,
droer-b3p2y1 Drosophila erecta (Fruit fly) GG25127 ,
droer-b3p2y2 Drosophila erecta (Fruit fly) GG25116 ,
droer-b3p7b4 Drosophila erecta (Fruit fly) GG12429 ,
droer-EST6 Drosophila erecta (Fruit fly) b-carboxyl esterase (EC 3.1.1.1) ,
droer-q670j5 Drosophila erecta (Fruit fly) (yest-6) Est-P EST7 .
CGI-58_ABHD5_ABHD4 :
droer-b3n9e1 Drosophila erecta (Fruit fly) GG23305 .
DPP4N_Peptidase_S9 :
droer-b3n5t7 Drosophila erecta (Fruit fly) GG23608 ,
droer-b3n577 Drosophila erecta (Fruit fly) GG25098 ,
droer-b3nd53 Drosophila erecta (Fruit fly) GG15695 ,
droer-b3nwa7 Drosophila erecta (Fruit fly) GG18210 ,
droer-b3p6w3 Drosophila erecta (Fruit fly) GG12305 .
Glutactin :
droer-b3n7d2 Drosophila erecta (Fruit fly) GG25298 ,
droer-b3n7d3 Drosophila erecta (Fruit fly) GG24059 ,
droer-b3n7d4 Drosophila erecta (Fruit fly) GG24058 .
Juvenile_hormone_esterase :
droer-b3npx2 Drosophila erecta (Fruit fly) GG20569 ,
droer-b3npx3 Drosophila erecta (Fruit fly) GG20568 .
Kynurenine-formamidase :
droer-b3n5s3 Drosophila erecta (Fruit fly). N-formylkynurenine formamidase .
LIDHydrolase :
droer-b3nb91 Drosophila erecta (Fruit fly) GG14609 .
Neuroligin :
droer-b3n5y4 Drosophila erecta (Fruit fly) GG10441 ,
droer-b3nyq3 Drosophila erecta (Fruit fly) GG14141 ,
droer-b3nz06 Drosophila erecta (Fruit fly) GG23789 .
Neurotactin :
droer-b3ndh9 Drosophila erecta (Fruit fly) GG13576 .
NLS3-Tex30 :
droer-b3nrd3 Drosophila erecta (Fruit fly) GG22446 .
OtherNon-catalytic_C :
droer-b3n8e4 Drosophila erecta (Fruit fly) GG24783 ,
droer-b3n8f8 Drosophila erecta (Fruit fly) GG24018 ,
droer-b3nq76 Drosophila erecta (Fruit fly) GG19954 ,
droer-b3nr28 Drosophila erecta (Fruit fly) GG20466 .
Pectinacetylesterase-Notum :
droer-b3ndq8 Drosophila erecta (Fruit fly) GG15944 .
PPase_methylesterase_euk :
droer-b3nfq9 Drosophila erecta (Fruit fly) Protein phosphatase methylesterase 1 .
Prolylcarboxypeptidase :
droer-b3nfk3 Drosophila erecta (Fruit fly) GG14395 ,
droer-b3nm11 Drosophila erecta (Fruit fly) GG21569 ,
droer-b3p0c0 Drosophila erecta (Fruit fly) GG23262 ,
droer-b3p0c1 Drosophila erecta (Fruit fly) GG23250 ,
droer-b3p0c2 Drosophila erecta (Fruit fly) GG23239 .
SERHL :
droer-b3ne66 Drosophila erecta (Fruit fly) GG13244 ,
droer-b3ne67 Drosophila erecta (Fruit fly) GG16172 ,
droer-b3n895 Drosophila erecta (Fruit fly). Uncharacterized protein .
Valacyclovir-hydrolase :
droer-b3p7h9 Drosophila erecta (Fruit fly) GG12512 Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
Sequence
Graphical view for this peptide sequence: droer-b3n612 Colored MSA for Gliotactin (raw)
MMHKLKYRDKLKWLLALLVLVSTCFMQTKGQTRDPRFYSRPGVDYHWPNP
GDPDYRTYTFNDRRYGHYQPNGYGANYPGRNPPGQYPQGMPNEDRFRFDP
NDPNARTQFPGVLAGWREDLQGKQRRDSLTLERDVFVTTNYGQVQGFKVY
MYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPRVHR
GWQLLQAVDFGPACPQPVRYTGATKGVMDMDEDCLYLNVYSPKTGAGVAQ
KYPVMVYIHGGEFIRGASNLFQGHILASFYDVVVVTLNYRLGALGFLSTG
DENSPGNYGILDQAMALRWVHDNIEFFNGDRNSITLFGPGAGGASAGLLM
VAPQTRNIVRRVIAQSGSALADWALIQDKYRAQNTSRVLGQLLGCSIESS
WKLVNCLRTGRSFYELGNAEFSPQVGSFPWGPVLDHNFTLPGDDWYEGWR
EKDWRFLTQTPETLIRAGKFNRNIQYMTGVTTQEAAFFVAQNESLSPYYE
LDGRFFDQKIREHVFRYNYTLNPNGVYEAIKYMYTFWPDPNNNTIIRDQY
INMLSDLYYRAPVDQMVKLMLEQKIPVYMYVLNTTVEALNLPQWRKYPHD
TERYFLTGAPFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYSNFARYG
NPTPQQVLGMHFQRAYQGEIRYLNINTTYNSSILLNYRQTECAFWTQYLP
TVIGVLVPTYPPTTEYWWEPKEPLQIAFWSMSVTCFFLIVLVVICCIMWR
NAKRQSDRFYDEDVFINGEGLEPEADARGVDNAHMVTNHHALRSRDNIYE
YRDSPSSKTLASKAHTDTTSLRSPSSLAMTQKSSSQASLKSGISLKETNG
HLVKQTERAATPRAQQNGSTAKVAAPVEEKRLLQPLSSTPVTQLQAEPAK
RVPTAASVSGSSRSTTPVPSARSNMHTTTATLSSQPAAQPRRTQLVEGVP
QTSV
Legend
This sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA
M M H K L K Y R D K L K W L L A L L V L V S T C F M Q T K G Q T R D P R F Y S R P G V D Y H W P N P G D P D Y R T Y T F N D R R Y G H Y Q P N G Y G A N Y P G R N P P G Q Y P Q G M P N E D R F R F D P N D P N A R T Q F P G V L A G W R E D L Q G K Q R R D S L T L E R D V F V T T N Y G Q V Q G F K V Y M Y D N P D P K S F Y R P Y H S T V D R V M G E C S V F L G I P Y A L P P T F E G R F K P P R V H R G W Q L L Q A V D F G P A C P Q P V R Y T G A T K G V M D M D E D C L Y L N V Y S P K T G A G V A Q K Y P V M V Y I H G G E F I R G A S N L F Q G H I L A S F Y D V V V V T L N Y R L G A L G F L S T G D E N S P G N Y G I L D Q A M A L R W V H D N I E F F N G D R N S I T L F G P G A G G A S A G L L M V A P Q T R N I V R R V I A Q S G S A L A D W A L I Q D K Y R A Q N T S R V L G Q L L G C S I E S S W K L V N C L R T G R S F Y E L G N A E F S P Q V G S F P W G P V L D H N F T L P G D D W Y E G W R E K D W R F L T Q T P E T L I R A G K F N R N I Q Y M T G V T T Q E A A F F V A Q N E S L S P Y Y E L D G R F F D Q K I R E H V F R Y N Y T L N P N G V Y E A I K Y M Y T F W P D P N N N T I I R D Q Y I N M L S D L Y Y R A P V D Q M V K L M L E Q K I P V Y M Y V L N T T V E A L N L P Q W R K Y P H D T E R Y F L T G A P F M D T E F F P K K E H L Q R N M W T D N D R N M S H F F M Q T Y S N F A R Y G N P T P Q Q V L G M H F Q R A Y Q G E I R Y L N I N T T Y N S S I L L N Y R Q T E C A F W T Q Y L P T V I G V L V P T Y P P T T E Y W W E P K E P L Q I A F W S M S V T C F F L I V L V V I C C I M W R N A K R Q S D R F Y D E D V F I N G E G L E P E A D A R G V D N A H M V T N H H A L R S R D N I Y E Y R D S P S S K T L A S K A H T D T T S L R S P S S L A M T Q K S S S Q A S L K S G I S L K E T N G H L V K Q T E R A A T P R A Q Q N G S T A K V A A P V E E K R L L Q P L S S T P V T Q L Q A E P A K R V P T A A S V S G S S R S T T P V P S A R S N M H T T T A T L S S Q P A A Q P R R T Q L V E G V P Q T S V
References
Title: Assembly reconciliationZimin AV , Smith DR , Sutton G , Yorke JA Ref: Bioinformatics, 24 :42, 2008 : PubMed Abstract ESTHER: Zimin_2008_Bioinformatics_24_42 PubMedSearch: Zimin 2008 Bioinformatics 24 42 PubMedID: 18057021 Gene_locus related to this paper: droan-ACHE ,
droan-b3lxv7 ,
droan-b3ly87 ,
droan-b3lyh4 ,
droan-b3lyh5 ,
droan-b3lyh7 ,
droan-b3lyh9 ,
droan-b3lyi0 ,
droan-b3lyi2 ,
droan-b3lyi3 ,
droan-b3lyi4 ,
droan-b3lyx4 ,
droan-b3lyx5 ,
droan-b3lyx6 ,
droan-b3lyx7 ,
droan-b3lyx9 ,
droan-b3lz72 ,
droan-b3m4e3 ,
droan-b3m5w1 ,
droan-b3m6i7 ,
droan-b3m7v2 ,
droan-b3m9p3 ,
droan-b3m524 ,
droan-b3m635 ,
droan-b3mdh7 ,
droan-b3mdw8 ,
droan-b3mee1 ,
droan-b3mf47 ,
droan-b3mf48 ,
droan-b3mg94 ,
droan-b3mgn6 ,
droan-b3mii3 ,
droan-b3mkr0 ,
droan-b3ml20 ,
droan-b3mly4 ,
droan-b3mly5 ,
droan-b3mly6 ,
droan-b3mnb5 ,
droan-b3muw4 ,
droan-b3muw8 ,
droan-b3n2j7 ,
droan-c5idb2 ,
droer-ACHE ,
droer-b3n5y4 ,
droer-b3n7d2 ,
droer-b3n7d3 ,
droer-b3n7d4 ,
droer-b3n7k8 ,
droer-b3n8e4 ,
droer-b3n8f7 ,
droer-b3n8f8 ,
droer-b3n9e1 ,
droer-b3n612 ,
droer-b3nar5 ,
droer-b3nb91 ,
droer-b3nct9 ,
droer-b3ndh9 ,
droer-b3ndq8 ,
droer-b3ne97 ,
droer-b3nfq9 ,
droer-b3nmh4 ,
droer-b3nmy2 ,
droer-b3npx2 ,
droer-b3npx3 ,
droer-b3nq76 ,
droer-b3nr28 ,
droer-b3nst4 ,
droer-b3nyp5.1 ,
droer-b3nyp5.2 ,
droer-b3nyp6 ,
droer-b3nyp7 ,
droer-b3nyp8 ,
droer-b3nyp9 ,
droer-b3nyq3 ,
droer-b3nz06 ,
droer-b3nz14 ,
droer-b3nzj0 ,
droer-b3p2x6 ,
droer-b3p2x7 ,
droer-b3p2x9 ,
droer-b3p2y1 ,
droer-b3p2y2 ,
droer-b3p7b4 ,
droer-EST6 ,
droer-q670j5 ,
drogr-ACHE ,
drogr-b4iww3 ,
drogr-b4iwy3 ,
drogr-b4ixf7 ,
drogr-b4ixh4 ,
drogr-b4j2u8 ,
drogr-b4j3v3 ,
drogr-b4j4g7 ,
drogr-b4j4x9 ,
drogr-b4j6e6 ,
drogr-b4j9c9 ,
drogr-b4j9y4 ,
drogr-b4j156 ,
drogr-b4j685 ,
drogr-b4ja76 ,
drogr-b4jcf0 ,
drogr-b4jcf1 ,
drogr-b4jdh6 ,
drogr-b4jdz1 ,
drogr-b4jdz2 ,
drogr-b4jdz4 ,
drogr-b4jf76 ,
drogr-b4jf79 ,
drogr-b4jf80 ,
drogr-b4jf81 ,
drogr-b4jf82 ,
drogr-b4jf83 ,
drogr-b4jf84 ,
drogr-b4jf85 ,
drogr-b4jf87 ,
drogr-b4jf91 ,
drogr-b4jf92 ,
drogr-b4jg66 ,
drogr-b4jnh9 ,
drogr-b4jpc6 ,
drogr-b4jql2 ,
drogr-b4jrh5 ,
drogr-b4jth3 ,
drogr-b4jti1 ,
drogr-b4jul5 ,
dromo-ACHE ,
dromo-b4k6q8 ,
dromo-b4k6q9 ,
dromo-b4k6r1 ,
dromo-b4k6r3 ,
dromo-b4k6r4 ,
dromo-b4k6r5 ,
dromo-b4k6r6 ,
dromo-b4k6r7 ,
dromo-b4k6r8 ,
dromo-b4k6r9 ,
dromo-b4k6s0 ,
dromo-b4k6s1 ,
dromo-b4k6s2 ,
dromo-b4k9c7 ,
dromo-b4k9d3 ,
dromo-b4ka74 ,
dromo-b4kaj4 ,
dromo-b4kdg2 ,
dromo-b4kdh4 ,
dromo-b4kdh5 ,
dromo-b4kdh6 ,
dromo-A0A0Q9XDF2 ,
dromo-b4kdh8.1 ,
dromo-b4kdh8.2 ,
dromo-b4kg04 ,
dromo-b4kg05 ,
dromo-b4kg06 ,
dromo-b4kg16 ,
dromo-b4kh20 ,
dromo-b4kh21 ,
dromo-b4kik0 ,
dromo-b4kjx0 ,
dromo-b4kki1 ,
dromo-b4klv8 ,
dromo-b4kp08 ,
dromo-b4kqa6 ,
dromo-b4kqa7 ,
dromo-b4kqa8 ,
dromo-b4kqh1 ,
dromo-b4kst4 ,
dromo-b4ksy6 ,
dromo-b4ktf5 ,
dromo-b4ktf6 ,
dromo-b4kvw2 ,
dromo-b4kxz6 ,
dromo-b4ky12 ,
dromo-b4ky36 ,
dromo-b4l0n8 ,
dromo-b4l6l9 ,
dromo-b4l084 ,
drovi-ACHE ,
drovi-b4lev2 ,
drovi-b4lg54 ,
drovi-b4lg72 ,
drovi-b4lgd5 ,
drovi-b4lgg0 ,
drovi-b4lgn2 ,
drovi-b4lk43 ,
drovi-b4ll59 ,
drovi-b4ll60 ,
drovi-b4lln3 ,
drovi-b4lmk4 ,
drovi-b4lmp0 ,
drovi-b4lpd0 ,
drovi-b4lps0 ,
drovi-b4lrp6 ,
drovi-b4lse7 ,
drovi-b4lse9 ,
drovi-b4lsf0 ,
drovi-b4lsn0 ,
drovi-b4lt32 ,
drovi-b4lxi9 ,
drovi-b4lxj8 ,
drovi-b4lyf3 ,
drovi-b4m0s0 ,
drovi-b4m4h7 ,
drovi-b4m4h8 ,
drovi-b4m4i0 ,
drovi-b4m4i2 ,
drovi-b4m4i3.A ,
drovi-b4m4i3.B ,
drovi-b4m4i4 ,
drovi-b4m4i5 ,
drovi-b4m4i6 ,
drovi-b4m4i7 ,
drovi-b4m4i8 ,
drovi-b4m4i9 ,
drovi-b4m4j2 ,
drovi-b4m5a0 ,
drovi-b4m5a1 ,
drovi-b4m5a2 ,
drovi-b4m7k9 ,
drovi-b4m9g9 ,
drovi-b4m9h0 ,
drovi-b4m599 ,
drovi-b4m918 ,
drovi-b4mfa4 ,
drovi-estes ,
drowi-ACHE ,
drowi-b4mjb9 ,
drowi-b4mqe9 ,
drowi-b4mqf0.2 ,
drowi-b4mqf1 ,
drowi-b4mqf3 ,
drowi-b4mqf4 ,
drowi-b4mqf5 ,
drowi-b4mqq6 ,
drowi-b4mrk3 ,
drowi-b4mtl5 ,
drowi-b4mug2 ,
drowi-b4mw32 ,
drowi-b4mw85 ,
drowi-b4mwz7 ,
drowi-b4mxn5 ,
drowi-b4my54 ,
drowi-b4myh5 ,
drowi-b4n1a7 ,
drowi-b4n3s9 ,
drowi-b4n3x7 ,
drowi-b4n6n0 ,
drowi-b4n6n7 ,
drowi-b4n6u6 ,
drowi-b4n7s6 ,
drowi-b4n7s7 ,
drowi-b4n7s8 ,
drowi-b4n899.1 ,
drowi-b4n8a1 ,
drowi-b4n8a2 ,
drowi-b4n8a3 ,
drowi-b4n8a4 ,
drowi-b4n8a9 ,
drowi-b4n023 ,
drowi-b4n075 ,
drowi-b4n543 ,
drowi-b4n888 ,
drowi-b4n889 ,
drowi-b4n891 ,
drowi-b4n893 ,
drowi-b4n895 ,
drowi-b4n897 ,
drowi-b4n898 ,
drowi-b4n899.2 ,
drowi-b4ng76 ,
drowi-b4nga7 ,
drowi-b4ngb5 ,
drowi-b4njk8 ,
drowi-b4nky0 ,
drowi-b4nn59 ,
drowi-b4nnc1 ,
drowi-b4nng1 ,
drowi-b4nng2 ,
droya-q71d76 ,
drowi-a0a0q9x0t3 ,
drovi-b4mcn9 Abstract
MOTIVATION: Many genomes are sequenced by a collaboration of several centers, and then each center produces an assembly using their own assembly software. The collaborators then pick the draft assembly that they judge to be the best and the information contained in the other assemblies is usually not used. METHODS: We have developed a technique that we call assembly reconciliation that can merge draft genome assemblies. It takes one draft assembly, detects apparent errors, and, when possible, patches the problem areas using pieces from alternative draft assemblies. It also closes gaps in places where one of the alternative assemblies has spanned the gap correctly. RESULTS: Using the Assembly Reconciliation technique, we produced reconciled assemblies of six Drosophila species in collaboration with Agencourt Bioscience and The J. Craig Venter Institute. These assemblies are now the official (CAF1) assemblies used for analysis. We also produced a reconciled assembly of Rhesus Macaque genome, and this assembly is available from our website http://www.genome.umd.edu. AVAILABILITY: The reconciliation software is available for download from http://www.genome.umd.edu/software.htm
Title: Evolution of genes and genomes on the Drosophila phylogenyClark AG , Eisen MB , Smith DR , Bergman CM , Oliver B , Markow TA , Kaufman TC , Kellis M , Gelbart W and MacCallum I <405 more author(s)> Clark AG , Eisen MB , Smith DR , Bergman CM , Oliver B , Markow TA , Kaufman TC , Kellis M , Gelbart W , Iyer VN , Pollard DA , Sackton TB , Larracuente AM , Singh ND , Abad JP , Abt DN , Adryan B , Aguade M , Akashi H , Anderson WW , Aquadro CF , Ardell DH , Arguello R , Artieri CG , Barbash DA , Barker D , Barsanti P , Batterham P , Batzoglou S , Begun D , Bhutkar A , Blanco E , Bosak SA , Bradley RK , Brand AD , Brent MR , Brooks AN , Brown RH , Butlin RK , Caggese C , Calvi BR , Bernardo de Carvalho A , Caspi A , Castrezana S , Celniker SE , Chang JL , Chapple C , Chatterji S , Chinwalla A , Civetta A , Clifton SW , Comeron JM , Costello JC , Coyne JA , Daub J , David RG , Delcher AL , Delehaunty K , Do CB , Ebling H , Edwards K , Eickbush T , Evans JD , Filipski A , Findeiss S , Freyhult E , Fulton L , Fulton R , Garcia AC , Gardiner A , Garfield DA , Garvin BE , Gibson G , Gilbert D , Gnerre S , Godfrey J , Good R , Gotea V , Gravely B , Greenberg AJ , Griffiths-Jones S , Gross S , Guigo R , Gustafson EA , Haerty W , Hahn MW , Halligan DL , Halpern AL , Halter GM , Han MV , Heger A , Hillier L , Hinrichs AS , Holmes I , Hoskins RA , Hubisz MJ , Hultmark D , Huntley MA , Jaffe DB , Jagadeeshan S , Jeck WR , Johnson J , Jones CD , Jordan WC , Karpen GH , Kataoka E , Keightley PD , Kheradpour P , Kirkness EF , Koerich LB , Kristiansen K , Kudrna D , Kulathinal RJ , Kumar S , Kwok R , Lander E , Langley CH , Lapoint R , Lazzaro BP , Lee SJ , Levesque L , Li R , Lin CF , Lin MF , Lindblad-Toh K , Llopart A , Long M , Low L , Lozovsky E , Lu J , Luo M , Machado CA , Makalowski W , Marzo M , Matsuda M , Matzkin L , McAllister B , McBride CS , McKernan B , McKernan K , Mendez-Lago M , Minx P , Mollenhauer MU , Montooth K , Mount SM , Mu X , Myers E , Negre B , Newfeld S , Nielsen R , Noor MA , O'Grady P , Pachter L , Papaceit M , Parisi MJ , Parisi M , Parts L , Pedersen JS , Pesole G , Phillippy AM , Ponting CP , Pop M , Porcelli D , Powell JR , Prohaska S , Pruitt K , Puig M , Quesneville H , Ram KR , Rand D , Rasmussen MD , Reed LK , Reenan R , Reily A , Remington KA , Rieger TT , Ritchie MG , Robin C , Rogers YH , Rohde C , Rozas J , Rubenfield MJ , Ruiz A , Russo S , Salzberg SL , Sanchez-Gracia A , Saranga DJ , Sato H , Schaeffer SW , Schatz MC , Schlenke T , Schwartz R , Segarra C , Singh RS , Sirot L , Sirota M , Sisneros NB , Smith CD , Smith TF , Spieth J , Stage DE , Stark A , Stephan W , Strausberg RL , Strempel S , Sturgill D , Sutton G , Sutton GG , Tao W , Teichmann S , Tobari YN , Tomimura Y , Tsolas JM , Valente VL , Venter E , Venter JC , Vicario S , Vieira FG , Vilella AJ , Villasante A , Walenz B , Wang J , Wasserman M , Watts T , Wilson D , Wilson RK , Wing RA , Wolfner MF , Wong A , Wong GK , Wu CI , Wu G , Yamamoto D , Yang HP , Yang SP , Yorke JA , Yoshida K , Zdobnov E , Zhang P , Zhang Y , Zimin AV , Baldwin J , Abdouelleil A , Abdulkadir J , Abebe A , Abera B , Abreu J , Acer SC , Aftuck L , Alexander A , An P , Anderson E , Anderson S , Arachi H , Azer M , Bachantsang P , Barry A , Bayul T , Berlin A , Bessette D , Bloom T , Blye J , Boguslavskiy L , Bonnet C , Boukhgalter B , Bourzgui I , Brown A , Cahill P , Channer S , Cheshatsang Y , Chuda L , Citroen M , Collymore A , Cooke P , Costello M , D'Aco K , Daza R , De Haan G , DeGray S , DeMaso C , Dhargay N , Dooley K , Dooley E , Doricent M , Dorje P , Dorjee K , Dupes A , Elong R , Falk J , Farina A , Faro S , Ferguson D , Fisher S , Foley CD , Franke A , Friedrich D , Gadbois L , Gearin G , Gearin CR , Giannoukos G , Goode T , Graham J , Grandbois E , Grewal S , Gyaltsen K , Hafez N , Hagos B , Hall J , Henson C , Hollinger A , Honan T , Huard MD , Hughes L , Hurhula B , Husby ME , Kamat A , Kanga B , Kashin S , Khazanovich D , Kisner P , Lance K , Lara M , Lee W , Lennon N , Letendre F , LeVine R , Lipovsky A , Liu X , Liu J , Liu S , Lokyitsang T , Lokyitsang Y , Lubonja R , Lui A , Macdonald P , Magnisalis V , Maru K , Matthews C , McCusker W , McDonough S , Mehta T , Meldrim J , Meneus L , Mihai O , Mihalev A , Mihova T , Mittelman R , Mlenga V , Montmayeur A , Mulrain L , Navidi A , Naylor J , Negash T , Nguyen T , Nguyen N , Nicol R , Norbu C , Norbu N , Novod N , O'Neill B , Osman S , Markiewicz E , Oyono OL , Patti C , Phunkhang P , Pierre F , Priest M , Raghuraman S , Rege F , Reyes R , Rise C , Rogov P , Ross K , Ryan E , Settipalli S , Shea T , Sherpa N , Shi L , Shih D , Sparrow T , Spaulding J , Stalker J , Stange-Thomann N , Stavropoulos S , Stone C , Strader C , Tesfaye S , Thomson T , Thoulutsang Y , Thoulutsang D , Topham K , Topping I , Tsamla T , Vassiliev H , Vo A , Wangchuk T , Wangdi T , Weiand M , Wilkinson J , Wilson A , Yadav S , Young G , Yu Q , Zembek L , Zhong D , Zimmer A , Zwirko Z , Alvarez P , Brockman W , Butler J , Chin C , Grabherr M , Kleber M , Mauceli E , MacCallum I (- 405) Ref: Nature, 450 :203, 2007 : PubMed Abstract ESTHER: Clark_2007_Nature_450_203 PubMedSearch: Clark 2007 Nature 450 203 PubMedID: 17994087 Gene_locus related to this paper: droan-ACHE ,
droan-b3lx10 ,
droan-b3lx75 ,
droan-b3lxv7 ,
droan-b3ly87 ,
droan-b3lyh4 ,
droan-b3lyh5 ,
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droan-b3lz72 ,
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dromo-b4k6a7 ,
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dromo-b4kd55.1 ,
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drosi-b4qzn8 ,
drosi-b4qzp2 ,
drosi-b4qzp3 ,
drosi-b4qzp4 ,
drosi-b4qzp5 ,
drosi-b4qzp6 ,
drosi-b4qzp7 ,
drosi-b4r1a4 ,
drosi-b4r025 ,
drosi-b4r207 ,
drosi-b4r662 ,
drosi-este6 ,
drosi-q670k8 ,
drovi-ACHE ,
drovi-b4lev2 ,
drovi-b4lf33 ,
drovi-b4lf51 ,
drovi-b4lg54 ,
drovi-b4lg72 ,
drovi-b4lgc6 ,
drovi-b4lgd5 ,
drovi-b4lgg0 ,
drovi-b4lgk5 ,
drovi-b4lgn2 ,
drovi-b4lh17 ,
drovi-b4lh18 ,
drovi-b4lk43 ,
drovi-b4ll59 ,
drovi-b4ll60 ,
drovi-b4llm5 ,
drovi-b4lln3 ,
drovi-b4lmk4 ,
drovi-b4lmp0 ,
drovi-b4lnr4 ,
drovi-b4lp47 ,
drovi-b4lpd0 ,
drovi-b4lps0 ,
drovi-b4lqc6 ,
drovi-b4lr00 ,
drovi-b4lrp6 ,
drovi-b4lrw2 ,
drovi-b4lse7 ,
drovi-b4lse9 ,
drovi-b4lsf0 ,
drovi-b4lsn0 ,
drovi-b4lsq5 ,
drovi-b4lt32 ,
drovi-b4ltr1 ,
drovi-b4lui7 ,
drovi-b4lui9 ,
drovi-b4luj8 ,
drovi-b4luk0 ,
drovi-b4luk3 ,
drovi-b4luk8 ,
drovi-b4luk9 ,
drovi-b4lul0 ,
drovi-b4lve2 ,
drovi-b4lxi9 ,
drovi-b4lxj8 ,
drovi-b4lyf3 ,
drovi-b4lyq2 ,
drovi-b4lyq3 ,
drovi-b4lz07 ,
drovi-b4lz13 ,
drovi-b4lz14 ,
drovi-b4lz15 ,
drovi-b4m0j7 ,
drovi-b4m0s0 ,
drovi-b4m2b6 ,
drovi-b4m4h7 ,
drovi-b4m4h8 ,
drovi-b4m4i0 ,
drovi-b4m4i2 ,
drovi-b4m4i3.A ,
drovi-b4m4i3.B ,
drovi-b4m4i4 ,
drovi-b4m4i5 ,
drovi-b4m4i6 ,
drovi-b4m4i7 ,
drovi-b4m4i8 ,
drovi-b4m4i9 ,
drovi-b4m4j2 ,
drovi-b4m5a0 ,
drovi-b4m5a1 ,
drovi-b4m5a2 ,
drovi-b4m6b9 ,
drovi-b4m7k9 ,
drovi-b4m9g9 ,
drovi-b4m9h0 ,
drovi-b4m564 ,
drovi-b4m599 ,
drovi-b4m918 ,
drovi-b4mb87 ,
drovi-b4mc71 ,
drovi-b4mfa4 ,
drowi-ACHE ,
drowi-b4mjb9 ,
drowi-b4mkt7 ,
drowi-b4mlc1 ,
drowi-b4mp68 ,
drowi-b4mqe9 ,
drowi-b4mqf0.2 ,
drowi-b4mqf1 ,
drowi-b4mqf3 ,
drowi-b4mqf4 ,
drowi-b4mqf5 ,
drowi-b4mqq6 ,
drowi-b4mrd1 ,
drowi-b4mrk3 ,
drowi-b4mtl5 ,
drowi-b4mug2 ,
drowi-b4muj8 ,
drowi-b4mv18 ,
drowi-b4mw32 ,
drowi-b4mw85 ,
drowi-b4mwp2 ,
drowi-b4mwp6 ,
drowi-b4mwq5 ,
drowi-b4mwr0 ,
drowi-b4mwr8 ,
drowi-b4mwr9 ,
drowi-b4mwt1 ,
drowi-b4mwz7 ,
drowi-b4mxn5 ,
drowi-b4my54 ,
drowi-b4myg1 ,
drowi-b4myh5 ,
drowi-b4n0d4 ,
drowi-b4n1a7 ,
drowi-b4n1c8 ,
drowi-b4n3s9 ,
drowi-b4n3x7 ,
drowi-b4n4x9 ,
drowi-b4n4y0 ,
drowi-b4n6m1 ,
drowi-b4n6n0 ,
drowi-b4n6n7 ,
drowi-b4n6u6 ,
drowi-b4n7s6 ,
drowi-b4n7s7 ,
drowi-b4n7s8 ,
drowi-b4n899.1 ,
drowi-b4n8a1 ,
drowi-b4n8a2 ,
drowi-b4n8a3 ,
drowi-b4n8a4 ,
drowi-b4n8a9 ,
drowi-b4n023 ,
drowi-b4n075 ,
drowi-b4n543 ,
drowi-b4n888 ,
drowi-b4n889 ,
drowi-b4n891 ,
drowi-b4n893 ,
drowi-b4n895 ,
drowi-b4n897 ,
drowi-b4n898 ,
drowi-b4n899.2 ,
drowi-b4nae3 ,
drowi-b4ner8 ,
drowi-b4ng76 ,
drowi-b4nga7 ,
drowi-b4ngb5 ,
drowi-b4nhz9 ,
drowi-b4nj18 ,
drowi-b4nj19 ,
drowi-b4nja7 ,
drowi-b4nja8 ,
drowi-b4nja9 ,
drowi-b4njk8 ,
drowi-b4nkc8 ,
drowi-b4nky0 ,
drowi-b4nl36 ,
drowi-b4nm27 ,
drowi-b4nn59 ,
drowi-b4nnc1 ,
drowi-b4nng1 ,
drowi-b4nng2 ,
droya-ACHE ,
droya-aes04 ,
droya-b4itg2 ,
droya-b4itg6 ,
droya-b4itu9 ,
droya-b4iuv4 ,
droya-b4iuv5 ,
droya-b4nxe6 ,
droya-b4nxg5 ,
droya-b4nxg6 ,
droya-b4nxg8 ,
droya-b4nxw4 ,
droya-b4ny57 ,
droya-b4ny58 ,
droya-b4ny86 ,
droya-b4nzz8 ,
droya-b4p0b5 ,
droya-b4p0q9 ,
droya-b4p0r0 ,
droya-b4p0r7 ,
droya-b4p0r8 ,
droya-b4p0r9 ,
droya-b4p0s0 ,
droya-b4p0s2 ,
droya-b4p0t0 ,
droya-b4p0t1 ,
droya-b4p3h4 ,
droya-b4p3x8 ,
droya-b4p5g8 ,
droya-b4p6c9 ,
droya-b4p6l9 ,
droya-b4p6r1 ,
droya-b4p6r2 ,
droya-b4p7u4 ,
droya-b4p8w7 ,
droya-b4p023 ,
droya-b4p241 ,
droya-b4p774 ,
droya-b4pat9 ,
droya-b4pbl1 ,
droya-b4pd22 ,
droya-b4pd70 ,
droya-b4pdm8 ,
droya-b4pet9 ,
droya-b4pff9 ,
droya-b4pga7 ,
droya-b4pgu0 ,
droya-b4pig3 ,
droya-b4pjt8 ,
droya-b4pka2 ,
droya-b4plh2 ,
droya-b4pma3 ,
droya-b4pmv3 ,
droya-b4pmv4 ,
droya-b4pmv5 ,
droya-b4pn92 ,
droya-b4pp65 ,
droya-b4ppc5 ,
droya-b4ppc6 ,
droya-b4ppc7 ,
droya-b4ppc8 ,
droya-b4pq03 ,
droya-b4prg6B ,
droya-b4prg9 ,
droya-b4prh3 ,
droya-b4prh4 ,
droya-b4prh6 ,
droya-b4prh7 ,
droya-b4psz8 ,
droya-b4psz9 ,
droya-b4pv22 ,
droya-b4q0g5 ,
droya-b4q246 ,
droya-EST6 ,
droya-q71d76 ,
drowi-b4n7m9 ,
drope-b4gkk1 ,
droer-b3n5s3 ,
drose-b4i1w5 ,
drowi-a0a0q9x0t3 ,
drogr-b4jvm7 ,
dromo-b4ku70 ,
drovi-b4mcn9 ,
drovi-b4lty2 ,
drogr-b4jdu1 ,
drovi-a0a0q9wiq8 ,
dromo-b4kf70 ,
drosi-b2zi86 ,
droya-b4p2y4 ,
drose-b2zic5 ,
droer-b3n895 Abstract
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves the precision and sensitivity of evolutionary inference, producing more robust results than single-genome analyses can provide. The genomes of 12 Drosophila species, ten of which are presented here for the first time (sechellia, simulans, yakuba, erecta, ananassae, persimilis, willistoni, mojavensis, virilis and grimshawi), illustrate how rates and patterns of sequence divergence across taxa can illuminate evolutionary processes on a genomic scale. These genome sequences augment the formidable genetic tools that have made Drosophila melanogaster a pre-eminent model for animal genetics, and will further catalyse fundamental research on mechanisms of development, cell biology, genetics, disease, neurobiology, behaviour, physiology and evolution. Despite remarkable similarities among these Drosophila species, we identified many putatively non-neutral changes in protein-coding genes, non-coding RNA genes, and cis-regulatory regions. These may prove to underlie differences in the ecology and behaviour of these diverse species.
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