Gene_Locus Report

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Gene_locus Report for: droya-EST6

Drosophila yakuba (Fruit fly) (and Drosophila santomea) b-carboxyl esterase (EC 3.1.1.1)

Comment
Drosophila yakuba (Fruit fly) GE21892


Relationship
Family|Carb_B_Arthropoda
Block| C
Position in NCBI Life Tree|Drosophila yakuba
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Panarthropoda: N E > Arthropoda: N E > Mandibulata: N E > Pancrustacea: N E > Hexapoda: N E > Insecta: N E > Dicondylia: N E > Pterygota: N E > Neoptera: N E > Holometabola: N E > Diptera: N E > Brachycera: N E > Muscomorpha: N E > Eremoneura: N E > Cyclorrhapha: N E > Schizophora: N E > Acalyptratae: N E > Ephydroidea: N E > Drosophilidae: N E > Drosophilinae: N E > Drosophilini: N E > Drosophila [fruit fly, genus]: N E > Sophophora: N E > melanogaster group: N E > melanogaster subgroup: N E > Drosophila yakuba: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acid identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
>3 Genbank links 1 more: AJ279007, AY804573, AY804572
3 UniProt : Q3L0C2, Q3L0C3, B4PGA6
>3 UniProt links 1 more: Q95ZE5, Q3L0C2, Q3L0C3
>3 Interpro links 1 more: Q95ZE5, Q3L0C2, Q3L0C3
>3 Pfam links 1 more: Q95ZE5, Q3L0C2, Q3L0C3
>3 PIRSF links 1 more: Q95ZE5, Q3L0C2, Q3L0C3
>3 SUPERFAM links 1 more: Q95ZE5, Q3L0C2, Q3L0C3
Sequence
Graphical view for this peptide sequence: droya-EST6
Colored MSA for Carb_B_Arthropoda (raw)
MNYVGLIIVLSCLWLTAIASDPDDPLLVQLPQGKLRGRDNGNYYSYESIP
YAEPPLGDLRLEAPEPYKQTWSDIFDATKAPVHCLQWDQFTSGDDKLVGA
EDCLTVSIYKPKNSSRSSYPVVAHIHGGAFMFGAAALNGHENVMREGKFI
LVKISYRLGPLGFASTSDTDLPGNYGLKDQRLALEWIRQNIASFGGEPEN
IVLIGHSAGGASVHLQMLREDFGQLAKAAISFSGNALDPWVVQEGGLGRA
FELGRIVGCGLAEDSASLKKCLKTKPASDLVSAVRNFLIFSYVPFAPFGP
VVEPSDAPEAFVTQEPSDVIKSGKFGQVPWAVTYVTEDGGYNAALLLAEW
NKYGKSGTVIEDLNDRWFDWAPYLLFYRDSKKTIKDMDDYSRRLRQQYLG
NRRFGIESYWDLQQLFTDILFKNSTQDSLDLHRKYGKSPAYAFVYDNPAD
KGIAQALTNRKDINFGTVHGDDYLLIFENAVRNLELRPDEQLISRNFINM
LADFALSDHGVLKYGECVFKDNVGSEKFELLSIHKDGCENKQYVEFP
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MNYVGLIIVLSCLWLTAIASDPDDPLLVQLPQGKLRGRDNGNYYSYESIP
YAEPPLGDLRLEAPEPYKQTWSDIFDATKAPVHCLQWDQFTSGDDKLVGA
EDCLTVSIYKPKNSSRSSYPVVAHIHGGAFMFGAAALNGHENVMREGKFI
LVKISYRLGPLGFASTSDTDLPGNYGLKDQRLALEWIRQNIASFGGEPEN
IVLIGHSAGGASVHLQMLREDFGQLAKAAISFSGNALDPWVVQEGGLGRA
FELGRIVGCGLAEDSASLKKCLKTKPASDLVSAVRNFLIFSYVPFAPFGP
VVEPSDAPEAFVTQEPSDVIKSGKFGQVPWAVTYVTEDGGYNAALLLAEW
NKYGKSGTVIEDLNDRWFDWAPYLLFYRDSKKTIKDMDDYSRRLRQQYLG
NRRFGIESYWDLQQLFTDILFKNSTQDSLDLHRKYGKSPAYAFVYDNPAD
KGIAQALTNRKDINFGTVHGDDYLLIFENAVRNLELRPDEQLISRNFINM
LADFALSDHGVLKYGECVFKDNVGSEKFELLSIHKDGCENKQYVEFP


References
1 more
    Title: Evolution of genes and genomes on the Drosophila phylogeny
    Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B, Markow TA, Kaufman TC, Kellis M, Gelbart W and MacCallum I <405 more author(s)>
    Ref: Nature, 450:203, 2007 : PubMed

            

    Title: Multilocus analysis of introgression between two sympatric sister species of Drosophila: Drosophila yakuba and D. santomea
    Llopart A, Lachaise D, Coyne JA
    Ref: Genetics, 171:197, 2005 : PubMed

            

    Title: An episode of accelerated amino acid change in Drosophila esterase-6 associated with a change in physiological function
    Oakeshott JG, van Papenrecht EA, Claudianos C, Morrish BC, Coppin C, Odgers WA
    Ref: Genetica, 110:231, 2000 : PubMed

            


Other Papers


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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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