Gene_Locus Report

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Gene_locus Report for: leima-q4fwg8

Leishmania major strain Friedlin phospholipase a2-like protein, putative

Relationship
Family|PAF-Acetylhydrolase
Block| X
Position in NCBI Life Tree|Leishmania major strain Friedlin
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Euglenozoa: N E > Kinetoplastida: N E > Trypanosomatidae: N E > Leishmaniinae: N E > Leishmania [genus]: N E > Leishmania [subgenus]: N E > Leishmania major species complex: N E > Leishmania major: N E > Leishmania major strain Friedlin: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
2 Genbank : CBZ12930, XP_003722696
1 UniProt : E9AFC6
1 UniProt : E9AFC6
1 Interpro : E9AFC6
1 Prodom : E9AFC6
1 Pfam : E9AFC6
1 PIRSF : E9AFC6
1 SUPERFAM : E9AFC6
Sequence
Graphical view for this peptide sequence: leima-q4fwg8
Colored MSA for PAF-Acetylhydrolase (raw)
MHPIFDYILSIHYLPAGASVLLSCLAAAWGVDWKVCIMMTCVGSLVTCAV
FYVQPLQCFSPLGGSFNVGTREVCGERGAMKPPVTIVYPTASGTPRSGIQ
YIPFGERSYLVGIASYSKVPYALVKDLWLLRKKMRPNAEPAPLFQRDGMP
RPMIVFSHGLGGFPHLYSTLLMDLAVRGAVVFALSHMDGSAAFCRDAERE
IRIPLNTQVGWTSEDRAPQLEVRIRETLNTIKRIRSGELLLALGYDKETV
DKYIEKEPRIHLLGHSFGGATCLAAALADTQAASERGGVSSIASTVVYDP
WMIPLQKTMFYDKLTDRKQPVHFTTPTLQIFSEEWVRSKEQHAFFEEVKA
IVDAQPRTTEESALVSAVDAKLKVMKTSWYTIKDYRGTGHLTCTDVSLFS
PVLYRAAYMTASPRGCIVAFAAETMRFIEKVSGPLPLDTKLLNDSALAAA
LRG
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MHPIFDYILSIHYLPAGASVLLSCLAAAWGVDWKVCIMMTCVGSLVTCAV
FYVQPLQCFSPLGGSFNVGTREVCGERGAMKPPVTIVYPTASGTPRSGIQ
YIPFGERSYLVGIASYSKVPYALVKDLWLLRKKMRPNAEPAPLFQRDGMP
RPMIVFSHGLGGFPHLYSTLLMDLAVRGAVVFALSHMDGSAAFCRDAERE
IRIPLNTQVGWTSEDRAPQLEVRIRETLNTIKRIRSGELLLALGYDKETV
DKYIEKEPRIHLLGHSFGGATCLAAALADTQAASERGGVSSIASTVVYDP
WMIPLQKTMFYDKLTDRKQPVHFTTPTLQIFSEEWVRSKEQHAFFEEVKA
IVDAQPRTTEESALVSAVDAKLKVMKTSWYTIKDYRGTGHLTCTDVSLFS
PVLYRAAYMTASPRGCIVAFAAETMRFIEKVSGPLPLDTKLLNDSALAAA
LRG


Reference
    Title: The genome of the kinetoplastid parasite, Leishmania major
    Ivens AC, Peacock CS, Worthey EA, Murphy L, Aggarwal G, Berriman M, Sisk E, Rajandream MA, Adlem E and Myler PJ <91 more author(s)>
    Ref: Science, 309:436, 2005 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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