Gene_locus Report for: neucr-5E6.090 Neurospora crassa hypothetical 79.2 kda protein
Comment
contains a long stretch of S at the C-term and of P in more N-term. In blast it can show homology with neurologins that are may be not relevant. Has an active site homologous to lipase 3 Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Fungi: N E > Dikarya: N E > Ascomycota: N E > saccharomyceta: N E > Pezizomycotina: N E > leotiomyceta: N E > sordariomyceta: N E > Sordariomycetes: N E > Sordariomycetidae: N E > Sordariales: N E > Sordariaceae: N E > Neurospora: N E > Neurospora crassa: N E 6_AlphaBeta_hydrolase :
neucr-64C2.070 Neurospora crassa hypothetical protein 64c2.070 ,
neucr-B10H4.010 Neurospora crassa related to cholesterol oxidase ,
neucr-B13B3.090 Neurospora crassa related to 3-oxoadipate enol-lactonase I ,
neucr-B15B24.080 Neurospora crassa related to 3-oxoadipate enol-lactonase II ,
neucr-NCU03158.1 Neurospora crassa hypothetical protein ,
neucr-NCU07909.1 Neurospora crassa predicted protein ,
neucr-q7ry06 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DS 1257 / FGSC 987) Predicted protein ,
neucr-q7s0g7 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DS 1257 / FGSC 987) Predicted protein ,
neucr-q7s3c6 Neurospora crassa hypothetical protein ,
neucr-q7s512 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DS 1257 / FGSC 987) Predicted protein ,
neucs-q8x0m1 Neurospora crassa Putative uncharacterized protein B11B23.040 .
A85-EsteraseD-FGH :
neucr-q7rxb4 Neurospora crassa hypothetical protein .
ABHD11-Acetyl_transferase :
neucr-B11C21.140 Neurospora crassa; Neurospora tetrasperma hypothetical protein b11c21.140 .
ABHD13-BEM46 :
neucr-q7sdx9 Neurospora crassa bud emergence 46 (BEM46) protein .
Acetylxylan_esterase :
neucr-B19A17.360 Neurospora crassa, Neurospora tetrasperma hypothetical protein b19a17.360 Acetylxylan esterase ,
neucr-q7s259 Neurospora crassa, Neurospora tetrasperma, hypothetical protein ,
neucr-q7s260 Neurospora crassa, Neurospora tetrasperma Cutinase-domain-containing protein .
Acidic_Lipase :
neucr-NCU02148.1 Neurospora crassa hypothetical protein ,
neucr-q7sgp3 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DS 1257 / FGSC 987) Putative uncharacterized protein .
AlphaBeta_hydrolase :
neucr-12F11.200 Neurospora crassa hypothetical protein ,
neucr-NCU00825.1 Neurospora crassa hypothetical protein ,
neucr-NCU02904.1 Neurospora crassa hypothetical protein ,
neucr-q7s3c8 Neurospora crassa hypothetical protein ,
neucr-q7sbn0 Neurospora crassa hypothetical protein .
Arb2_domain :
neucr-q7ry64 Neurospora crassa; Neurospora tetrasperma. Histone deacetylase hda1 .
Bacterial_esterase :
neucr-q7s4f8 Neurospora crassa hypothetical protein .
BD-FAE :
neucr-64C2.080 Neurospora crassa hypothetical protein 64c2.080 .
Canar_LipB :
neucr-q7ryd2 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DS 1257 / FGSC 987) Lipase B .
Carboxypeptidase_S10 :
neucr-B7H23.190 Neurospora crassa Pheromone-processing carboxypeptidase kex1 ,
neucr-CBPYA Neurospora crassa, Sordaria macrospora, Carboxypeptidase Y homolog A ,
neucr-pepf Neurospora crassa probable serine-type carboxypeptidase f cpdS ,
neucr-q7s216 Neurospora crassa hypothetical protein .
CGI-58_ABHD5_ABHD4 :
neucr-NCU06332.1 Neurospora crassa hypothetical protein .
Cocaine_esterase :
neucr-B11O8.160 Neurospora crassa hypothetical protein b11o8.160 .
Dienelactone_hydrolase :
neucr-B8P8.080 Neurospora crassa hypothetical protein b8p8.080 ,
neucr-B14A6.290 Neurospora crassa conserved hypothetical protein ,
neucr-B18E6.050 Neurospora crassa hypothetical protein b18e6.050 ,
neucr-q7s3m2 Neurospora crassa hypothetical protein ,
neucr-q7s6c5 Neurospora crassa hypothetical protein ,
neucr-q7se51 Neurospora crassa hypothetical protein .
DPP4N_Peptidase_S9 :
neucr-q7shu8 Neurospora crassa Sordaria macrospora .
Duf_676 :
neucr-18A7.150 Neurospora crassa conserved hypothetical protein ,
neucr-q7s828 Neurospora crassa hypothetical protein .
Duf_726 :
neucr-q7sez8 Neurospora crassa Predicted protein ,
neucr-q7sga3 Neurospora crassa Putative uncharacterized protein ,
neucr-q9p6a7 Neurospora crassa Putative uncharacterized protein B1D1.130 .
Duf_829 :
neucr-q7s2c5 Neurospora crassa Predicted protein ,
neucr-q7s2p4 Neurospora crassa Predicted protein ,
neucr-q872l1 Neurospora crassa Putative uncharacterized protein 64C2.020 .
Duf_1100-S :
neucr-q7s5m2 Neurospora crassa hypothetical protein ,
neucr-q7sha3 Neurospora crassa hypothetical protein .
Epoxide_hydrolase :
neucr-NCU00350.1 Neurospora crassa hypothetical protein ,
neucr-NCU02924.1 Neurospora crassa hypothetical protein .
Esterase_phb :
neucr-faeb Neurospora crassa (faeb) Feruloyl esterase B NcFae1 .
FaeC :
neucs-a0a0b0dk23 Neurospora crassa. Carbohydrate esterase family 1 protein ,
neucr-FAED Neurospora crassa; Neurospora tetrasperma Feruloyl esterase D faeD-3.544 NcFaeD .
FSH1 :
neucr-q7sgj0 Neurospora crassa; Neurospora tetrasperma hypothetical protein .
Fungal_carboxylesterase_lipase :
neucr-90C4.300 Neurospora crassa, Neurospora tetrasperma, 90C4.300 gene close to EStA contig 90C4 ,
neucr-B23G1.090 Neurospora crassa, Neurospora tetrasperma, gene B23G1.090 ,
neucr-NCU00292.1 Neurospora crassa, Neurospora tetrasperma, hypothetical protein ,
neucr-NCU02679.1 Neurospora crassa Neurospora tetrasperma hypothetical protein related to triacylglycerol lipase II ,
neucr-NCU04930.1 Neurospora crassa, Neurospora tetrasperma, hypothetical protein ,
neucr-NCU06573.1 Neurospora crassa, Neurospora tetrasperma, hypothetical protein ,
neucr-NCU08752.1 Neurospora crassa, Neurospora tetrasperma, hypothetical protein ,
neucr-NCU09575.1 Neurospora crassa, Neurospora tetrasperma, hypothetical protein ,
neucr-NCU10022.1 Neurospora crassa, Neurospora tetrasperma, hypothetical protein .
Fusarinine_C_esterase_sidJ :
neucr-q7rzk2 Neurospora crassa. hypothetical protein .
Glucuronoyl_esterase :
neucr-q7s1x0 Neurospora crassa, Neurospora tetrasperma, Putative uncharacterized protein .
Haloacetate_dehalogenase :
neucr-q7s4j4 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DS 1257 / FGSC 987) Predicted protein .
Haloperoxidase :
neucr-a7uwh6 Neurospora crassa Putative uncharacterized protein .
Homoserine_transacetylase :
neucr-MET5 Neurospora crassa homoserine o-acetyltransferase (EC 2.3.1.31) ,
neucr-NCU00536.1 Neurospora crassa hypothetical protein .
Hormone-sensitive_lipase_like :
neucr-B14D6.130 Neurospora crassa B14D6.130 ,
neucr-B23L21.110 Neurospora crassa B23L21.110 ,
neucr-NCU07081.1 Neurospora crassa hypothetical protein ,
neucr-q7s5d6 Neurospora crassa hypothetical protein ,
neucr-q7s5v8 Neurospora crassa hypothetical protein ,
neucr-q7s8h2 Neurospora crassa hypothetical protein ,
neucr-q7s082 Neurospora crassa hypothetical protein ,
neucr-q7s283 Neurospora crassa hypothetical protein ,
neucr-q7sbf9 Neurospora crassa hypothetical protein .
Kynurenine-formamidase :
neucr-B14D6.180 Neurospora crassa conserved hypothetical protein ,
neucr-f5hbr2 Neurospora crassa, Neurospora tetrasperma, N-formylkynurenine formamidase .
LIDHydrolase :
neucr-q7s070 Neurospora crassa Predicted protein .
Lipase_3 :
neucr-a7uw78 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), hypothetical protein ,
neucr-ATG15 Neurospora crassa Putative lipase atg-15 ,
neucr-B11N2.60 Neurospora crassa probable triacylglycerol lipase precursor ,
neucr-q7sha5 Neurospora crassa hypothetical protein .
LYsophospholipase_carboxylesterase :
neucr-5F3.240 Neurospora crassa conserved hypothetical protein ,
neucr-apth1 Neurospora crassa B2J23.70 related to lysophospholipase acyl-protein thioesterase 1 (EC 3.1.2.-) .
Monoglyceridelipase_lysophospholip :
neucr-7F4.210 Neurospora crassa hypothetical protein 7f4.210 .
MpaH :
neucr-B23L21.350 Neurospora crassa related to host-specific ak-toxin akt2 .
PAF-Acetylhydrolase :
neucr-q7s2b3 Neurospora crassa Related to platelet-activating factor acetylhydrolase ,
neucr-q7scr4 Neurospora crassa, Neurospora tetrasperma, hypothetical protein .
Palmitoyl-protein_thioesterase :
neucr-q7s897 Neurospora crassa hypothetical protein .
PC-sterol_acyltransferase :
neucr-q7s4e3 Neurospora crassa hypothetical protein .
PGAP1 :
neucr-q6mfs7 Neurospora crassa related to sphingosine-1-phosphate lyase ,
neucr-q7rxv5 Neurospora crassa predicted protein (hypothetical protein b11e5.130) ,
neucr-q7sff7 Neurospora crassa predicted protein .
PPase_methylesterase_euk :
neucr-ppme1 Neurospora crassa protein phosphatase methylesterase 1 (EC 3.1.1.-) (pme-1) .
Proline_iminopeptidase :
neucr-NCU07415.1 Neurospora crassa hypothetical protein .
Prolylcarboxypeptidase :
neucr-q7s134 Neurospora crassa hypothetical protein ,
neucr-q7sea3 Neurospora crassa hypothetical protein .
Prolyl_oligopeptidase_S9 :
neucr-q7sdw5 Neurospora crassa hypothetical protein .
Steryl_acetyl_hydrolase :
neucr-a7uwy7 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) hypothetical protein .
Tannase :
neucr-q7s2u9 Neurospora crassa hypothetical protein .
Thioesterase :
neucr-q7s736 Neurospora crassa hypothetical protein Warning: This entry is a compilation of different species or line or strain with more than 90% amino acid identity. You can
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(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) Neurospora crassa OR74A:
N ,
E .
Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
Sequence
Graphical view for this peptide sequence: neucr-5E6.090 Colored MSA for Lipase_3 (raw)
MARVPNAPTRCVRIGLSPSPSNADSILSWAAINPHQPSSTLNQPSLTPKK
PDPRPPVIYRLHQSGAHETATTAGHWRLSGSTAANIHSYSPHDWHKGQPF
EPAGLLPSPTGWTPSSPQPIIVNQHHYYLGTPGPNSPPPQLIQSIPPIPP
PKNSTSSLNKMPAGSVMEVASDISQVPSLAHGFDGMLSHWPDNKTQLLNQ
GAALYDQISGRLNDVLTRIDLNQISGEEKEHFTWRPAVQETSYPPSSSMV
GSRSAVKSGIRRSSSHSREHREHRDREHREHSSSTNSGGYFAKVDLYANS
RLPTDLPPLRLYIPTWPLLCLAAQYSERVYERPKGAERDAHVNADWRTGA
KAMVIKSVPMDYVNTIVFAIRGTATFMDWAVNLNSNPTSPEGFLDDPGNL
CHAGFLDVARNMVQPVARRLRQLLDEDPSRSSYSLLITGHSAGGAVAALL
YSHILSTTKEAQSELTAVAGCFKRVHCVTFGTPPISIIPLKKPEDFERRP
ELKKSLFLSFINEGDPVARADKAYVKSLLELYTSPAPSINPLSPAPSRKG
PSSSSDLNMRMKPAGQKSSRSSLQSSKSGKSTDARSTERRSSSGSSSHHT
SSSSGSSHRSSSRSRSSTSSASSALTTTSTTASSVSSSHTSSSSPGPTWK
LPASTLSCAGRLVVLRSGDPKSRLKGKGKTVEERLNEGVVAHVVASEEML
RGVVWGDPLMHVMKLYKGRIETLAVGAVTAKGY
Legend
This sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA
M A R V P N A P T R C V R I G L S P S P S N A D S I L S W A A I N P H Q P S S T L N Q P S L T P K K P D P R P P V I Y R L H Q S G A H E T A T T A G H W R L S G S T A A N I H S Y S P H D W H K G Q P F E P A G L L P S P T G W T P S S P Q P I I V N Q H H Y Y L G T P G P N S P P P Q L I Q S I P P I P P P K N S T S S L N K M P A G S V M E V A S D I S Q V P S L A H G F D G M L S H W P D N K T Q L L N Q G A A L Y D Q I S G R L N D V L T R I D L N Q I S G E E K E H F T W R P A V Q E T S Y P P S S S M V G S R S A V K S G I R R S S S H S R E H R E H R D R E H R E H S S S T N S G G Y F A K V D L Y A N S R L P T D L P P L R L Y I P T W P L L C L A A Q Y S E R V Y E R P K G A E R D A H V N A D W R T G A K A M V I K S V P M D Y V N T I V F A I R G T A T F M D W A V N L N S N P T S P E G F L D D P G N L C H A G F L D V A R N M V Q P V A R R L R Q L L D E D P S R S S Y S L L I T G H S A G G A V A A L L Y S H I L S T T K E A Q S E L T A V A G C F K R V H C V T F G T P P I S I I P L K K P E D F E R R P E L K K S L F L S F I N E G D P V A R A D K A Y V K S L L E L Y T S P A P S I N P L S P A P S R K G P S S S S D L N M R M K P A G Q K S S R S S L Q S S K S G K S T D A R S T E R R S S S G S S S H H T S S S S G S S H R S S S R S R S S T S S A S S A L T T T S T T A S S V S S S H T S S S S P G P T W K L P A S T L S C A G R L V V L R S G D P K S R L K G K G K T V E E R L N E G V V A H V V A S E E M L R G V V W G D P L M H V M K L Y K G R I E T L A V G A V T A K G Y
Reference
Title: The genome sequence of the filamentous fungus Neurospora crassaGalagan JE , Calvo SE , Borkovich KA , Selker EU , Read ND , Jaffe D , FitzHugh W , Ma LJ , Smirnov S and Birren B <67 more author(s)> Galagan JE , Calvo SE , Borkovich KA , Selker EU , Read ND , Jaffe D , FitzHugh W , Ma LJ , Smirnov S , Purcell S , Rehman B , Elkins T , Engels R , Wang S , Nielsen CB , Butler J , Endrizzi M , Qui D , Ianakiev P , Bell-Pedersen D , Nelson MA , Werner-Washburne M , Selitrennikoff CP , Kinsey JA , Braun EL , Zelter A , Schulte U , Kothe GO , Jedd G , Mewes W , Staben C , Marcotte E , Greenberg D , Roy A , Foley K , Naylor J , Stange-Thomann N , Barrett R , Gnerre S , Kamal M , Kamvysselis M , Mauceli E , Bielke C , Rudd S , Frishman D , Krystofova S , Rasmussen C , Metzenberg RL , Perkins DD , Kroken S , Cogoni C , Macino G , Catcheside D , Li W , Pratt RJ , Osmani SA , DeSouza CP , Glass L , Orbach MJ , Berglund JA , Voelker R , Yarden O , Plamann M , Seiler S , Dunlap J , Radford A , Aramayo R , Natvig DO , Alex LA , Mannhaupt G , Ebbole DJ , Freitag M , Paulsen I , Sachs MS , Lander ES , Nusbaum C , Birren B (- 67) Ref: Nature, 422 :859, 2003 : PubMed Abstract ESTHER: Galagan_2003_Nature_422_859 PubMedSearch: Galagan 2003 Nature 422 859 PubMedID: 12712197 Gene_locus related to this paper: neucr-5E6.090 ,
neucr-64C2.080 ,
neucr-90C4.300 ,
neucr-a7uw78 ,
neucr-a7uwh6 ,
neucr-a7uwy7 ,
neucr-apth1 ,
neucr-ATG15 ,
neucr-B7H23.190 ,
neucr-B11O8.160 ,
neucr-B13B3.090 ,
neucr-B14D6.130 ,
neucr-B18E6.050 ,
neucr-B19A17.360 ,
neucr-B23G1.090 ,
neucr-CBPYA ,
neucr-MET5 ,
neucr-NCU00292.1 ,
neucr-NCU00350.1 ,
neucr-NCU00536.1 ,
neucr-NCU00825.1 ,
neucr-NCU02148.1 ,
neucr-NCU02679.1 ,
neucr-NCU02904.1 ,
neucr-NCU02924.1 ,
neucr-NCU03158.1 ,
neucr-NCU04930.1 ,
neucr-NCU06332.1 ,
neucr-NCU06573.1 ,
neucr-NCU07081.1 ,
neucr-NCU07415.1 ,
neucr-NCU07909.1 ,
neucr-NCU08752.1 ,
neucr-NCU09575.1 ,
neucr-NCU10022.1 ,
neucr-ppme1 ,
neucr-q6mfs7 ,
neucr-q7rxb4 ,
neucr-q7rxv5 ,
neucr-q7ry06 ,
neucr-q7ryd2 ,
neucr-q7rzk2 ,
neucr-q7s0g7 ,
neucr-q7s1x0 ,
neucr-q7s2b3 ,
neucr-q7s2c5 ,
neucr-q7s2p4 ,
neucr-q7s2u9 ,
neucr-q7s3c6 ,
neucr-q7s3c8 ,
neucr-q7s3m2 ,
neucr-q7s4e3 ,
neucr-q7s4f8 ,
neucr-q7s4j4 ,
neucr-q7s5d6 ,
neucr-q7s5m2 ,
neucr-q7s5v8 ,
neucr-q7s6c5 ,
neucr-q7s8h2 ,
neucr-q7s070 ,
neucr-q7s082 ,
neucr-q7s134 ,
neucr-q7s216 ,
neucr-q7s259 ,
neucr-q7s260 ,
neucr-q7s283 ,
neucr-q7s512 ,
neucr-q7s736 ,
neucr-q7s828 ,
neucr-q7s897 ,
neucr-q7sbf9 ,
neucr-q7sbn0 ,
neucr-q7scr4 ,
neucr-q7sdw5 ,
neucr-q7sdx9 ,
neucr-q7se51 ,
neucr-q7sea3 ,
neucr-q7sez8 ,
neucr-q7sff7 ,
neucr-q7sga3 ,
neucr-q7sgj0 ,
neucr-q7sgp3 ,
neucr-q7sha3 ,
neucr-q7sha5 ,
neucr-q7shu8 ,
neucr-q9p6a7 ,
neucr-q872l1 ,
neucr-f5hbr2 ,
neucr-q7ry64 Abstract
Neurospora crassa is a central organism in the history of twentieth-century genetics, biochemistry and molecular biology. Here, we report a high-quality draft sequence of the N. crassa genome. The approximately 40-megabase genome encodes about 10,000 protein-coding genes--more than twice as many as in the fission yeast Schizosaccharomyces pombe and only about 25% fewer than in the fruitfly Drosophila melanogaster. Analysis of the gene set yields insights into unexpected aspects of Neurospora biology including the identification of genes potentially associated with red light photobiology, genes implicated in secondary metabolism, and important differences in Ca2+ signalling as compared with plants and animals. Neurospora possesses the widest array of genome defence mechanisms known for any eukaryotic organism, including a process unique to fungi called repeat-induced point mutation (RIP). Genome analysis suggests that RIP has had a profound impact on genome evolution, greatly slowing the creation of new genes through genomic duplication and resulting in a genome with an unusually low proportion of closely related genes.
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