Dimethylhydroxycarbaphen

General

Type : Muscarinic antagonist, Propionate, Carbamate, Pro-Drug, Multitarget, Not A\/B H target

Chemical_Nomenclature : 2-(diethylamino)ethyl 2-[4-(dimethylcarbamoyloxy)phenyl]-2-(4-hydroxyphenyl)propanoate

Canonical SMILES : CCN(CC)CCOC(=O)C(C)(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OC(=O)N(C)C

InChI : InChI=1S\/C24H32N2O5\/c1-6-26(7-2)16-17-30-22(28)24(3,18-8-12-20(27)13-9-18)19-10-14-21(15-11-19)31-23(29)25(4)5\/h8-15,27H,6-7,16-17H2,1-5H3

InChIKey : WSSHBIZVZFEFDX-UHFFFAOYSA-N

Other name(s) : CHEMBL288482  ||  BDBM50018226  ||  2-(4-Dimethylcarbamoyloxy-phenyl)-2-(4-hydroxy-phenyl)-propionic acid 2-diethylamino-ethyl ester


MW : 428.5

Formula : C24H32N2O5

CAS_number :

PubChem : 14537192

UniChem : WSSHBIZVZFEFDX-UHFFFAOYSA-N

Target

Families : Dimethylhydroxycarbaphen ligand of proteins in family
BCHE

Protein :
human-BCHE

References (1)

Title : Binary antidotes for organophosphate poisoning: aprophen analogues that are both antimuscarinics and carbamates - Leader_1989_J.Med.Chem_32_1522
Author(s) : Leader H , Smejkal RM , Payne CS , Padilla FN , Doctor BP , Gordon RK , Chiang PK
Ref : Journal of Medicinal Chemistry , 32 :1522 , 1989
Abstract :
PubMedSearch : Leader_1989_J.Med.Chem_32_1522
PubMedID: 2738887