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Propionate

General

Propionic acid, propanoic acid is a naturally occurring carboxylic acid. Formula CH3CH2CO2H (C3). Acid moiety of some ester substrate. Can be the product of hydrolysis of an ester and act as an inhibitor of the enzyme and be found in the active site in some structures
Inhibitor Main targeted enzyme families Type Structure
Youssoufene-A1 Thioesterase-YsfF-HD Biphenyl Propionate
Sofosbuvir Carb_B_Chordata Pro-Drug Drug Propionate Not AlphaBeta Hydrolase target
2-(cyclohexylmethyl)propanedioic-acid Carboxypeptidase_S10 Propionate Product-like inhibitor
Hypaphorine ACHE Not AlphaBeta Hydrolase target Natural Derivative of Tryptophan Indole Propionate Trimethylammonium Ammonium
Remdesivir Carb_B_Chordata Pro-Drug Drug Not AlphaBeta Hydrolase target Propionate Triazine Cyanide
Lactic-acid Cutinase Polyesterase-lipase-cutinase Product-like inhibitor Propionate
CHEMBL3145341 Carboxypeptidase_S10 Carboxamide Pyrazole Propionate
Bromophenyl-methoxyphenyl-pyrazol-carbamoyl-cyclohexyl-propanoate-Cpd2 Carboxypeptidase_S10 Carboxamide Pyrazole Propionate
CHEMBL2171392 Carboxypeptidase_S10 Carboxamide Pyrazole Propionate
Alanycarb ACHE Insecticide Carbamate Sulfur Compound Propionate
Benfuracarb ACHE Insecticide Carbamate Sulfur Compound Benzofuran Propionate
Pyridophen-10 ACHE Muscarinic antagonist Propionate Carbamate Pro-Drug Multitarget Not AlphaBeta Hydrolase target PET probe
Dimethylhydroxycarbaphen BCHE Muscarinic antagonist Propionate Carbamate Pro-Drug Multitarget Not AlphaBeta Hydrolase target
Aprophen ACHE BCHE Muscarinic antagonist Propionate
Atracurium BCHE Not AlphaBeta Hydrolase target Neuromuscular Nondepolarizing Agents Drug Isoquinoline Propionate Dimethoxyphenyl
Atropine ACHE Not AlphaBeta Hydrolase target Muscarinic antagonist Drug Alkaloid Natural Azabicyclo Propionate
N-methylatropine Not AlphaBeta Hydrolase target Muscarinic antagonist Propionate
Cisatracurium BCHE Propionate Dimethoxyphenyl Isoquinoline Neuromuscular Nondepolarizing Agents Nicotinic antagonist Bisquaternary Not AlphaBeta Hydrolase target