FAP-2286
Theranostic ligand for FAP. FAP-2286 is a cyclic peptide composed of seven amino acids, with two cysteine residues forming a cycle through an aromatic group connected to a DOTA chelator DOTA (Tetraxetan 2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]) chelating agent for metallic ions (177Lu and 68Ga for example) used in PET imaging. Fibroblast activation protein (FAP)-targeted tracer belonging to the group of FAP inhibitors (FAPi), conjugated, through the macrocyclic chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA), to the radioisotope gallium Ga 68 or [132/135La/117Lu/90Y/225Ac]
General
Type : Peptide, PET probe, Tetrazacyclododec, Sulfur Compound
Chemical_Nomenclature : (5R,11S,17S,20S,23S,26S,29R)-23-(3-amino-3-oxopropyl)-26-benzyl-5-(hexanoylamino)-20-[(1R)-1-hydroxyethyl]-6,12,18,21,24,27-hexaoxo-35-[2-[[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetyl]amino]ethylsulfanylmethyl]-3,31-dithia-7,13,19,22,25,28-hexazatetracyclo[31.3.1.07,11.013,17]heptatriaconta-1(37),33,35-triene-29-carboxylic acid
Canonical SMILES : CCCCCC(=O)N[C@H]1CSCC2=CC(=CC(=C2)CSCCNC(=O)CN3CCN(CCN(CCN(CC3)CC(=O)O)CC(=O)O)CC(=O)O)CSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]4CCCN4C(=O)[C@@H]5CCCN5C1=O)[C@@H](C)O)CCC(=O)N)CC6=CC=CC=C6)C(=O)O
InChI : InChI=1S\/C67H99N13O18S3\/c1-3-4-6-15-55(83)70-50-41-100-39-46-30-45(38-99-29-18-69-56(84)34-75-21-23-76(35-57(85)86)25-27-78(37-59(89)90)28-26-77(24-22-75)36-58(87)88)31-47(32-46)40-101-42-51(67(97)98)73-62(92)49(33-44-11-7-5-8-12-44)72-61(91)48(16-17-54(68)82)71-64(94)60(43(2)81)74-63(93)52-13-9-19-79(52)66(96)53-14-10-20-80(53)65(50)95\/h5,7-8,11-12,30-32,43,48-53,60,81H,3-4,6,9-10,13-29,33-42H2,1-2H3,(H2,68,82)(H,69,84)(H,70,83)(H,71,94)(H,72,91)(H,73,92)(H,74,93)(H,85,86)(H,87,88)(H,89,90)(H,97,98)\/t43-,48+,49+,50+,51+,52+,53+,60+\/m1\/s1
InChIKey : UHKLVUPDBJFFBB-ZCDGVBLYSA-N
Other name(s) : FAPI-2286 || EX-A7733 || FAP-2286 || AT43730 || DA-53114 || HY-147057 || [Cys(tMeBn(DOTA-AET))-Pro-Pro-Thr-Gln-Phe-Cys]-OH || 3BP-3554 || 68Ga-Fapi-2286 || (68Ga)-DOTA-fapi-2286 || FAPI-2286 Ga-68
MW : 1470.8
Formula : C67H99N13O18S3
CAS_number : 2581741-18-4
PubChem : 163408889
UniChem : UHKLVUPDBJFFBB-ZCDGVBLYSA-N
Target
Families : FAP-2286 ligand of proteins in family
DPP4N_Peptidase_S9
Protein :
human-FAP
References (36)
| Title : Preclinical evaluation of [(13x)La]La-FAP-2286 as a novel theranostic agent for tumors expressing fibroblast activation protein - Shirpour_2025_Sci.Rep_15_7475 |
| Author(s) : Shirpour A , Hadadi A , Zolghadri S , Vosoughi S , Rajabifar S |
| Ref : Sci Rep , 15 :7475 , 2025 |
| Abstract : |
| PubMedSearch : Shirpour_2025_Sci.Rep_15_7475 |
| PubMedID: 40032959 |
| Title : Preclinical Evaluation of (68)Ga\/(177)Lu-Labeled FAP-Targeted Peptide for Tumor Radiopharmaceutical Imaging and Therapy - Wang_2025_J.Nucl.Med_66_250 |
| Author(s) : Wang R , Huang M , Wang W , Li M , Wang Y , Tian R |
| Ref : J Nucl Med , 66 :250 , 2025 |
| Abstract : |
| PubMedSearch : Wang_2025_J.Nucl.Med_66_250 |
| PubMedID: 39848766 |
| Title : Preclinical evaluation of [(13x)La]La-FAP-2286 as a novel theranostic agent for tumors expressing fibroblast activation protein - Shirpour_2025_Sci.Rep_15_7475 |
| Author(s) : Shirpour A , Hadadi A , Zolghadri S , Vosoughi S , Rajabifar S |
| Ref : Sci Rep , 15 :7475 , 2025 |
| Abstract : |
| PubMedSearch : Shirpour_2025_Sci.Rep_15_7475 |
| PubMedID: 40032959 |
| Title : Preclinical Evaluation of (68)Ga\/(177)Lu-Labeled FAP-Targeted Peptide for Tumor Radiopharmaceutical Imaging and Therapy - Wang_2025_J.Nucl.Med_66_250 |
| Author(s) : Wang R , Huang M , Wang W , Li M , Wang Y , Tian R |
| Ref : J Nucl Med , 66 :250 , 2025 |
| Abstract : |
| PubMedSearch : Wang_2025_J.Nucl.Med_66_250 |
| PubMedID: 39848766 |
| Title : Preclinical evaluation of [(13x)La]La-FAP-2286 as a novel theranostic agent for tumors expressing fibroblast activation protein - Shirpour_2025_Sci.Rep_15_7475 |
| Author(s) : Shirpour A , Hadadi A , Zolghadri S , Vosoughi S , Rajabifar S |
| Ref : Sci Rep , 15 :7475 , 2025 |
| Abstract : |
| PubMedSearch : Shirpour_2025_Sci.Rep_15_7475 |
| PubMedID: 40032959 |
| Title : Preclinical Evaluation of (68)Ga\/(177)Lu-Labeled FAP-Targeted Peptide for Tumor Radiopharmaceutical Imaging and Therapy - Wang_2025_J.Nucl.Med_66_250 |
| Author(s) : Wang R , Huang M , Wang W , Li M , Wang Y , Tian R |
| Ref : J Nucl Med , 66 :250 , 2025 |
| Abstract : |
| PubMedSearch : Wang_2025_J.Nucl.Med_66_250 |
| PubMedID: 39848766 |
| Title : Preclinical study and first-in-human imaging of [(18)F]FAP-2286, and comparison with 2-[(18)F]FDG PET\/CT in various cancer patients - Liu_2024_Eur.J.Nucl.Med.Mol.Imaging_51_2012 |
| Author(s) : Liu L , Zhong J , Zhang Z , Ye X , Wang X , Liu S |
| Ref : Eur J Nucl Med Mol Imaging , 51 :2012 , 2024 |
| Abstract : |
| PubMedSearch : Liu_2024_Eur.J.Nucl.Med.Mol.Imaging_51_2012 |
| PubMedID: 38326656 |
| Title : Initial Experience with (68)Ga-FAP-2286 PET Imaging in Patients with Urothelial Cancer - Koshkin_2024_J.Nucl.Med_65_199 |
| Author(s) : Koshkin VS , Kumar V , Kline B , Escobar D , Aslam M , Cooperberg MR , Aggarwal RR , de Kouchkovsky I , Chou J , Meng MV , Friedlander T , Porten S , Hope TA |
| Ref : J Nucl Med , 65 :199 , 2024 |
| Abstract : |
| PubMedSearch : Koshkin_2024_J.Nucl.Med_65_199 |
| PubMedID: 38212070 |
| Title : (68)Ga-FAP-2286 PET of Solid Tumors: Biodistribution, Dosimetry, and Comparison with (18)F-FDG - Kline_2024_J.Nucl.Med_65_938 |
| Author(s) : Kline B , Yadav S , Seo Y , Ippisch RC , Castillo J , Aggarwal RR , Kelley RK , Behr SC , Flavell RR , Lawhn-Heath C , Melisko M , Rugo HS , Wang V , Yom SS , Ha P , Jiang F , Hope TA |
| Ref : J Nucl Med , 65 :938 , 2024 |
| Abstract : |
| PubMedSearch : Kline_2024_J.Nucl.Med_65_938 |
| PubMedID: 38697672 |
| Title : Feasibility and therapeutic potential of [(177)Lu]Lu-FAPI-2286 in patients with advanced metastatic sarcoma - Banihashemian_2024_Eur.J.Nucl.Med.Mol.Imaging_52_237 |
| Author(s) : Banihashemian SS , Akbari ME , Pirayesh E , Divband G , Abolhosseini Shahrnoy A , Nami R , Mazidi SM , Nasiri M |
| Ref : Eur J Nucl Med Mol Imaging , 52 :237 , 2024 |
| Abstract : |
| PubMedSearch : Banihashemian_2024_Eur.J.Nucl.Med.Mol.Imaging_52_237 |
| PubMedID: 39060377 |
| Title : Comparison of (68)Ga-FAP-2286 and (18)F-FDG PET\/CT in the diagnosis of advanced lung cancer - Xiang_2024_Front.Oncol_14_1413771 |
| Author(s) : Xiang F , Zhang Y , Tan X , Zhang J , Li T , Yan Y , Ma W , Chen Y |
| Ref : Front Oncol , 14 :1413771 , 2024 |
| Abstract : |
| PubMedSearch : Xiang_2024_Front.Oncol_14_1413771 |
| PubMedID: 39011487 |
| Title : [(68)Ga]Ga-FAP-2286, a novel promising theragnostic approach for PET\/CT imaging in patients with various type of metastatic cancers - Banihashemian_2024_Eur.J.Nucl.Med.Mol.Imaging_51_1981 |
| Author(s) : Banihashemian SS , Divband G , Pirayesh E , Nikkholgh B , Amini H , Shahrnoy AA , Nami R , Akbari ME |
| Ref : Eur J Nucl Med Mol Imaging , 51 :1981 , 2024 |
| Abstract : |
| PubMedSearch : Banihashemian_2024_Eur.J.Nucl.Med.Mol.Imaging_51_1981 |
| PubMedID: 38376804 |
| Title : Preclinical study and first-in-human imaging of [(18)F]FAP-2286, and comparison with 2-[(18)F]FDG PET\/CT in various cancer patients - Liu_2024_Eur.J.Nucl.Med.Mol.Imaging_51_2012 |
| Author(s) : Liu L , Zhong J , Zhang Z , Ye X , Wang X , Liu S |
| Ref : Eur J Nucl Med Mol Imaging , 51 :2012 , 2024 |
| Abstract : |
| PubMedSearch : Liu_2024_Eur.J.Nucl.Med.Mol.Imaging_51_2012 |
| PubMedID: 38326656 |
| Title : Initial Experience with (68)Ga-FAP-2286 PET Imaging in Patients with Urothelial Cancer - Koshkin_2024_J.Nucl.Med_65_199 |
| Author(s) : Koshkin VS , Kumar V , Kline B , Escobar D , Aslam M , Cooperberg MR , Aggarwal RR , de Kouchkovsky I , Chou J , Meng MV , Friedlander T , Porten S , Hope TA |
| Ref : J Nucl Med , 65 :199 , 2024 |
| Abstract : |
| PubMedSearch : Koshkin_2024_J.Nucl.Med_65_199 |
| PubMedID: 38212070 |
| Title : (68)Ga-FAP-2286 PET of Solid Tumors: Biodistribution, Dosimetry, and Comparison with (18)F-FDG - Kline_2024_J.Nucl.Med_65_938 |
| Author(s) : Kline B , Yadav S , Seo Y , Ippisch RC , Castillo J , Aggarwal RR , Kelley RK , Behr SC , Flavell RR , Lawhn-Heath C , Melisko M , Rugo HS , Wang V , Yom SS , Ha P , Jiang F , Hope TA |
| Ref : J Nucl Med , 65 :938 , 2024 |
| Abstract : |
| PubMedSearch : Kline_2024_J.Nucl.Med_65_938 |
| PubMedID: 38697672 |
| Title : Feasibility and therapeutic potential of [(177)Lu]Lu-FAPI-2286 in patients with advanced metastatic sarcoma - Banihashemian_2024_Eur.J.Nucl.Med.Mol.Imaging_52_237 |
| Author(s) : Banihashemian SS , Akbari ME , Pirayesh E , Divband G , Abolhosseini Shahrnoy A , Nami R , Mazidi SM , Nasiri M |
| Ref : Eur J Nucl Med Mol Imaging , 52 :237 , 2024 |
| Abstract : |
| PubMedSearch : Banihashemian_2024_Eur.J.Nucl.Med.Mol.Imaging_52_237 |
| PubMedID: 39060377 |
| Title : Comparison of (68)Ga-FAP-2286 and (18)F-FDG PET\/CT in the diagnosis of advanced lung cancer - Xiang_2024_Front.Oncol_14_1413771 |
| Author(s) : Xiang F , Zhang Y , Tan X , Zhang J , Li T , Yan Y , Ma W , Chen Y |
| Ref : Front Oncol , 14 :1413771 , 2024 |
| Abstract : |
| PubMedSearch : Xiang_2024_Front.Oncol_14_1413771 |
| PubMedID: 39011487 |
| Title : [(68)Ga]Ga-FAP-2286, a novel promising theragnostic approach for PET\/CT imaging in patients with various type of metastatic cancers - Banihashemian_2024_Eur.J.Nucl.Med.Mol.Imaging_51_1981 |
| Author(s) : Banihashemian SS , Divband G , Pirayesh E , Nikkholgh B , Amini H , Shahrnoy AA , Nami R , Akbari ME |
| Ref : Eur J Nucl Med Mol Imaging , 51 :1981 , 2024 |
| Abstract : |
| PubMedSearch : Banihashemian_2024_Eur.J.Nucl.Med.Mol.Imaging_51_1981 |
| PubMedID: 38376804 |
| Title : Preclinical study and first-in-human imaging of [(18)F]FAP-2286, and comparison with 2-[(18)F]FDG PET\/CT in various cancer patients - Liu_2024_Eur.J.Nucl.Med.Mol.Imaging_51_2012 |
| Author(s) : Liu L , Zhong J , Zhang Z , Ye X , Wang X , Liu S |
| Ref : Eur J Nucl Med Mol Imaging , 51 :2012 , 2024 |
| Abstract : |
| PubMedSearch : Liu_2024_Eur.J.Nucl.Med.Mol.Imaging_51_2012 |
| PubMedID: 38326656 |
| Title : Initial Experience with (68)Ga-FAP-2286 PET Imaging in Patients with Urothelial Cancer - Koshkin_2024_J.Nucl.Med_65_199 |
| Author(s) : Koshkin VS , Kumar V , Kline B , Escobar D , Aslam M , Cooperberg MR , Aggarwal RR , de Kouchkovsky I , Chou J , Meng MV , Friedlander T , Porten S , Hope TA |
| Ref : J Nucl Med , 65 :199 , 2024 |
| Abstract : |
| PubMedSearch : Koshkin_2024_J.Nucl.Med_65_199 |
| PubMedID: 38212070 |
| Title : (68)Ga-FAP-2286 PET of Solid Tumors: Biodistribution, Dosimetry, and Comparison with (18)F-FDG - Kline_2024_J.Nucl.Med_65_938 |
| Author(s) : Kline B , Yadav S , Seo Y , Ippisch RC , Castillo J , Aggarwal RR , Kelley RK , Behr SC , Flavell RR , Lawhn-Heath C , Melisko M , Rugo HS , Wang V , Yom SS , Ha P , Jiang F , Hope TA |
| Ref : J Nucl Med , 65 :938 , 2024 |
| Abstract : |
| PubMedSearch : Kline_2024_J.Nucl.Med_65_938 |
| PubMedID: 38697672 |
| Title : Feasibility and therapeutic potential of [(177)Lu]Lu-FAPI-2286 in patients with advanced metastatic sarcoma - Banihashemian_2024_Eur.J.Nucl.Med.Mol.Imaging_52_237 |
| Author(s) : Banihashemian SS , Akbari ME , Pirayesh E , Divband G , Abolhosseini Shahrnoy A , Nami R , Mazidi SM , Nasiri M |
| Ref : Eur J Nucl Med Mol Imaging , 52 :237 , 2024 |
| Abstract : |
| PubMedSearch : Banihashemian_2024_Eur.J.Nucl.Med.Mol.Imaging_52_237 |
| PubMedID: 39060377 |
| Title : Comparison of (68)Ga-FAP-2286 and (18)F-FDG PET\/CT in the diagnosis of advanced lung cancer - Xiang_2024_Front.Oncol_14_1413771 |
| Author(s) : Xiang F , Zhang Y , Tan X , Zhang J , Li T , Yan Y , Ma W , Chen Y |
| Ref : Front Oncol , 14 :1413771 , 2024 |
| Abstract : |
| PubMedSearch : Xiang_2024_Front.Oncol_14_1413771 |
| PubMedID: 39011487 |
| Title : [(68)Ga]Ga-FAP-2286, a novel promising theragnostic approach for PET\/CT imaging in patients with various type of metastatic cancers - Banihashemian_2024_Eur.J.Nucl.Med.Mol.Imaging_51_1981 |
| Author(s) : Banihashemian SS , Divband G , Pirayesh E , Nikkholgh B , Amini H , Shahrnoy AA , Nami R , Akbari ME |
| Ref : Eur J Nucl Med Mol Imaging , 51 :1981 , 2024 |
| Abstract : |
| PubMedSearch : Banihashemian_2024_Eur.J.Nucl.Med.Mol.Imaging_51_1981 |
| PubMedID: 38376804 |
| Title : Fibroblast activation protein-targeted radionuclide therapy: background, opportunities, and challenges of first (pre)clinical studies - Prive_2023_Eur.J.Nucl.Med.Mol.Imaging_50_1906 |
| Author(s) : Prive BM , Boussihmad MA , Timmermans B , van Gemert WA , Peters SMB , Derks YHW , van Lith SAM , Mehra N , Nagarajah J , Heskamp S , Westdorp H |
| Ref : Eur J Nucl Med Mol Imaging , 50 :1906 , 2023 |
| Abstract : |
| PubMedSearch : Prive_2023_Eur.J.Nucl.Med.Mol.Imaging_50_1906 |
| PubMedID: 36813980 |
| Title : PET Imaging of Fibroblast Activation Protein in Various Types of Cancer Using (68)Ga-FAP-2286: Comparison with (18)F-FDG and (68)Ga-FAPI-46 in a Single-Center, Prospective Study - Pang_2023_J.Nucl.Med_64_386 |
| Author(s) : Pang Y , Zhao L , Meng T , Xu W , Lin Q , Wu H , Zhang J , Chen X , Sun L , Chen H |
| Ref : J Nucl Med , 64 :386 , 2023 |
| Abstract : |
| PubMedSearch : Pang_2023_J.Nucl.Med_64_386 |
| PubMedID: 36215571 |
| Title : Fibroblast activation protein-targeted radionuclide therapy: background, opportunities, and challenges of first (pre)clinical studies - Prive_2023_Eur.J.Nucl.Med.Mol.Imaging_50_1906 |
| Author(s) : Prive BM , Boussihmad MA , Timmermans B , van Gemert WA , Peters SMB , Derks YHW , van Lith SAM , Mehra N , Nagarajah J , Heskamp S , Westdorp H |
| Ref : Eur J Nucl Med Mol Imaging , 50 :1906 , 2023 |
| Abstract : |
| PubMedSearch : Prive_2023_Eur.J.Nucl.Med.Mol.Imaging_50_1906 |
| PubMedID: 36813980 |
| Title : PET Imaging of Fibroblast Activation Protein in Various Types of Cancer Using (68)Ga-FAP-2286: Comparison with (18)F-FDG and (68)Ga-FAPI-46 in a Single-Center, Prospective Study - Pang_2023_J.Nucl.Med_64_386 |
| Author(s) : Pang Y , Zhao L , Meng T , Xu W , Lin Q , Wu H , Zhang J , Chen X , Sun L , Chen H |
| Ref : J Nucl Med , 64 :386 , 2023 |
| Abstract : |
| PubMedSearch : Pang_2023_J.Nucl.Med_64_386 |
| PubMedID: 36215571 |
| Title : Fibroblast activation protein-targeted radionuclide therapy: background, opportunities, and challenges of first (pre)clinical studies - Prive_2023_Eur.J.Nucl.Med.Mol.Imaging_50_1906 |
| Author(s) : Prive BM , Boussihmad MA , Timmermans B , van Gemert WA , Peters SMB , Derks YHW , van Lith SAM , Mehra N , Nagarajah J , Heskamp S , Westdorp H |
| Ref : Eur J Nucl Med Mol Imaging , 50 :1906 , 2023 |
| Abstract : |
| PubMedSearch : Prive_2023_Eur.J.Nucl.Med.Mol.Imaging_50_1906 |
| PubMedID: 36813980 |
| Title : PET Imaging of Fibroblast Activation Protein in Various Types of Cancer Using (68)Ga-FAP-2286: Comparison with (18)F-FDG and (68)Ga-FAPI-46 in a Single-Center, Prospective Study - Pang_2023_J.Nucl.Med_64_386 |
| Author(s) : Pang Y , Zhao L , Meng T , Xu W , Lin Q , Wu H , Zhang J , Chen X , Sun L , Chen H |
| Ref : J Nucl Med , 64 :386 , 2023 |
| Abstract : |
| PubMedSearch : Pang_2023_J.Nucl.Med_64_386 |
| PubMedID: 36215571 |
| Title : Preclinical evaluation of FAP-2286 for fibroblast activation protein targeted radionuclide imaging and therapy - Zboralski_2022_Eur.J.Nucl.Med.Mol.Imaging_49_3651 |
| Author(s) : Zboralski D , Hoehne A , Bredenbeck A , Schumann A , Nguyen M , Schneider E , Ungewiss J , Paschke M , Haase C , von Hacht JL , Kwan T , Lin KK , Lenore J , Harding TC , Xiao J , Simmons AD , Mohan AM , Beindorff N , Reineke U , Smerling C , Osterkamp F |
| Ref : Eur J Nucl Med Mol Imaging , 49 :3651 , 2022 |
| Abstract : |
| PubMedSearch : Zboralski_2022_Eur.J.Nucl.Med.Mol.Imaging_49_3651 |
| PubMedID: 35608703 |
| Title : Feasibility, Biodistribution, and Preliminary Dosimetry in Peptide-Targeted Radionuclide Therapy of Diverse Adenocarcinomas Using (177)Lu-FAP-2286: First-in-Humans Results - Baum_2022_J.Nucl.Med_63_415 |
| Author(s) : Baum RP , Schuchardt C , Singh A , Chantadisai M , Robiller FC , Zhang J , Mueller D , Eismant A , Almaguel F , Zboralski D , Osterkamp F , Hoehne A , Reineke U , Smerling C , Kulkarni HR |
| Ref : J Nucl Med , 63 :415 , 2022 |
| Abstract : |
| PubMedSearch : Baum_2022_J.Nucl.Med_63_415 |
| PubMedID: 34168013 |
| Title : Preclinical evaluation of FAP-2286 for fibroblast activation protein targeted radionuclide imaging and therapy - Zboralski_2022_Eur.J.Nucl.Med.Mol.Imaging_49_3651 |
| Author(s) : Zboralski D , Hoehne A , Bredenbeck A , Schumann A , Nguyen M , Schneider E , Ungewiss J , Paschke M , Haase C , von Hacht JL , Kwan T , Lin KK , Lenore J , Harding TC , Xiao J , Simmons AD , Mohan AM , Beindorff N , Reineke U , Smerling C , Osterkamp F |
| Ref : Eur J Nucl Med Mol Imaging , 49 :3651 , 2022 |
| Abstract : |
| PubMedSearch : Zboralski_2022_Eur.J.Nucl.Med.Mol.Imaging_49_3651 |
| PubMedID: 35608703 |
| Title : Feasibility, Biodistribution, and Preliminary Dosimetry in Peptide-Targeted Radionuclide Therapy of Diverse Adenocarcinomas Using (177)Lu-FAP-2286: First-in-Humans Results - Baum_2022_J.Nucl.Med_63_415 |
| Author(s) : Baum RP , Schuchardt C , Singh A , Chantadisai M , Robiller FC , Zhang J , Mueller D , Eismant A , Almaguel F , Zboralski D , Osterkamp F , Hoehne A , Reineke U , Smerling C , Kulkarni HR |
| Ref : J Nucl Med , 63 :415 , 2022 |
| Abstract : |
| PubMedSearch : Baum_2022_J.Nucl.Med_63_415 |
| PubMedID: 34168013 |
| Title : Preclinical evaluation of FAP-2286 for fibroblast activation protein targeted radionuclide imaging and therapy - Zboralski_2022_Eur.J.Nucl.Med.Mol.Imaging_49_3651 |
| Author(s) : Zboralski D , Hoehne A , Bredenbeck A , Schumann A , Nguyen M , Schneider E , Ungewiss J , Paschke M , Haase C , von Hacht JL , Kwan T , Lin KK , Lenore J , Harding TC , Xiao J , Simmons AD , Mohan AM , Beindorff N , Reineke U , Smerling C , Osterkamp F |
| Ref : Eur J Nucl Med Mol Imaging , 49 :3651 , 2022 |
| Abstract : |
| PubMedSearch : Zboralski_2022_Eur.J.Nucl.Med.Mol.Imaging_49_3651 |
| PubMedID: 35608703 |
| Title : Feasibility, Biodistribution, and Preliminary Dosimetry in Peptide-Targeted Radionuclide Therapy of Diverse Adenocarcinomas Using (177)Lu-FAP-2286: First-in-Humans Results - Baum_2022_J.Nucl.Med_63_415 |
| Author(s) : Baum RP , Schuchardt C , Singh A , Chantadisai M , Robiller FC , Zhang J , Mueller D , Eismant A , Almaguel F , Zboralski D , Osterkamp F , Hoehne A , Reineke U , Smerling C , Kulkarni HR |
| Ref : J Nucl Med , 63 :415 , 2022 |
| Abstract : |
| PubMedSearch : Baum_2022_J.Nucl.Med_63_415 |
| PubMedID: 34168013 |