Neostigmine~Prostigmine

A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE- ESERINE, does not cross the blood-brain barrier. Parasympathomimetic as well as Neostigmine Methyl Sulfate. Used to reverse action of neuromuscular blockers and snake venoms. There is also Nor-physostigmine(...-dimethyl aminoformate).Neostigmine sulfoxymethane (Juvastigmin,Kirkstigmine, Neostigmeth, Normastigmin, Polstigmine, Synstigmine, Syntostigmin, Hodostin, Proserin Hoffman-La-Roche prostigmine was marketed in the early 1930s for the treatment of glaucoma, myasthenia gravis, to increase gut and bladder functions.

General

Type : Carbamate, Trimethylammonium

Chemical_Nomenclature : [3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium

Canonical SMILES : CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C || CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.COS(=O)(=O)O

InChI : InChI=1S\/C12H19N2O2\/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5\/h6-9H,1-5H3\/q+1 || InChI=1S\/C12H19N2O2.CH4O4S\/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5\;1-5-6(2,3)4\/h6-9H,1-5H3\;1H3,(H,2,3,4)\/q+1\;

InChIKey : ALWKGYPQUAPLQC-UHFFFAOYSA-N || OSZNNLWOYWAHSS-UHFFFAOYSA-N

Other name(s) : (m-hydroxyphenyl) trimethylammonium bromide dimethyl carbamate  ||  (3-dimethylcarbamoxyphenyl)trimethylammonium bromide  ||  Kirkstigmine  ||  Neostigmeth  ||  Normastigmin  ||  Polstigmine  ||  Synstigmine  ||  Syntostigmin  ||  Hodostin  ||  Proserin  ||  Neo proserine  ||  neo-Proserin  ||  Eustigmin  ||  Neoserine  ||  Proserine  ||  Stigmanol  ||  Stigmosan  ||  Prostigmin  ||  Prostigmine  ||  Synstigmin  ||  Neostigmine methosulfate  ||  Neostigmine  ||  Philostigmine  ||  Eustigmine


MW : 303.21

Formula : C12H19BrN2O2

CAS_number : 114-80-7,    59-99-4

PubChem : 4456,    417610

UniChem : ALWKGYPQUAPLQC-UHFFFAOYSA-N,    OSZNNLWOYWAHSS-UHFFFAOYSA-N

IUPHAR : 8993

Wikipedia : Neostigmine

Target

Families : Neostigmine~Prostigmine ligand of proteins in family
ACHE BCHE

References (66)

Title : Inhibition of cholinesterase-associated aryl acylamidase activity by anticholinesterase agents: focus on drugs potentially effective in Alzheimer's disease - Costagli_1998_Biochem.Pharmacol_55_1733
Author(s) : Costagli C , Galli A
Ref : Biochemical Pharmacology , 55 :1733 , 1998
Abstract :
PubMedSearch : Costagli_1998_Biochem.Pharmacol_55_1733
PubMedID: 9634011

Title : Recycling of acetylcholine following impulse transmission in rat muscle revealed in the presence of neostigmine - Uramoto_1998_Clin.Exp.Pharmacol.Physiol_25_44
Author(s) : Uramoto I , Miyamoto K , Watanabe K , Totsuka T
Ref : Clinical & Experimental Pharmacology & Physiology , 25 :44 , 1998
Abstract :
PubMedSearch : Uramoto_1998_Clin.Exp.Pharmacol.Physiol_25_44
PubMedID: 9493558

Title : Neostigmine competitively inhibited nicotinic acetylcholine receptors in sympathetic neurons - Zheng_1998_Life.Sci_62_1171
Author(s) : Zheng JQ , He XP , Yang AZ , Liu CG
Ref : Life Sciences , 62 :1171 , 1998
Abstract :
PubMedSearch : Zheng_1998_Life.Sci_62_1171
PubMedID: 9519798

Title : Does neostigmine have a deleterious effect on the resistance of colonic anastomoses? - Garcia-Olmo_1998_Eur.J.Anaesthesiol_15_38
Author(s) : Garcia-Olmo DC , Garcia-Rivas M , Garcia-Olmo D
Ref : European Journal of Anaesthesiology , 15 :38 , 1998
Abstract :
PubMedSearch : Garcia-Olmo_1998_Eur.J.Anaesthesiol_15_38
PubMedID: 9522139

Title : Effects of oral clonidine on heart rate changes after neostigmine- atropine administration - Kimura_1998_Anesthesiology_88_1507
Author(s) : Kimura T , Tanaka M , Nishikawa T
Ref : Anesthesiology , 88 :1507 , 1998
Abstract :
PubMedSearch : Kimura_1998_Anesthesiology_88_1507
PubMedID: 9637644

Title : The efficacy of intrathecal neostigmine, intrathecal morphine, and their combination for post-cesarean section analgesia - Chung_1998_Anesth.Analg_87_341
Author(s) : Chung CJ , Kim JS , Park HS , Chin YJ
Ref : Anesthesia & Analgesia , 87 :341 , 1998
Abstract :
PubMedSearch : Chung_1998_Anesth.Analg_87_341
PubMedID: 9706928

Title : Intrathecal neostigmine, but not sympathectomy, relieves mechanical allodynia in a rat model of neuropathic pain - Lavand'homme_1998_Anesthesiology_89_493
Author(s) : Lavand'homme P , Pan HL , Eisenach JC
Ref : Anesthesiology , 89 :493 , 1998
Abstract :
PubMedSearch : Lavand'homme_1998_Anesthesiology_89_493
PubMedID: 9710409

Title : Postoperative analgesia by intra-articular neostigmine in patients undergoing knee arthroscopy - Yang_1998_Anesthesiology_88_334
Author(s) : Yang LC , Chen LM , Wang CJ , Buerkle H
Ref : Anesthesiology , 88 :334 , 1998
Abstract :
PubMedSearch : Yang_1998_Anesthesiology_88_334
PubMedID: 9477052

Title : Effects of neostigmine and atropine on basal and handling-induced acetylcholine output from ventral hippocampus - Moor_1998_Neurosci_82_819
Author(s) : Moor E , Schirm E , Jacso J , Westerink BH
Ref : Neuroscience , 82 :819 , 1998
Abstract :
PubMedSearch : Moor_1998_Neurosci_82_819
PubMedID: 9483538

Title : Dopaminergic regulation of striatal acetylcholine release: the critical role of acetylcholinesterase inhibition - Acquas_1998_J.Neurochem_70_1088
Author(s) : Acquas E , Fibiger HC
Ref : Journal of Neurochemistry , 70 :1088 , 1998
Abstract :
PubMedSearch : Acquas_1998_J.Neurochem_70_1088
PubMedID: 9489729

Title : Effects of four anticholinesterase-anticholinergic combinations and tracheal extubation on QTc interval of the ECG, heart rate and arterial pressure - Saarnivaara_1998_Acta.Anaesthesiol.Scand_42_460
Author(s) : Saarnivaara L , Simola M
Ref : Acta Anaesthesiologica Scandinavica , 42 :460 , 1998
Abstract :
PubMedSearch : Saarnivaara_1998_Acta.Anaesthesiol.Scand_42_460
PubMedID: 9563867

Title : Effects of intrathecal neostigmine, bupivacaine, and their combination on sympathetic nerve activity in rats - Pan_1998_Anesthesiology_88_481
Author(s) : Pan HL , Song HK , Eisenach JC
Ref : Anesthesiology , 88 :481 , 1998
Abstract :
PubMedSearch : Pan_1998_Anesthesiology_88_481
PubMedID: 9477069

Title : Central and peripheral analgesia mediated by the acetylcholinesterase- inhibitor neostigmine in the rat inflamed knee joint model - Buerkle_1998_Anesth.Analg_86_1027
Author(s) : Buerkle H , Boschin M , Marcus MA , Brodner G , Wusten R , Van Aken H
Ref : Anesthesia & Analgesia , 86 :1027 , 1998
Abstract :
PubMedSearch : Buerkle_1998_Anesth.Analg_86_1027
PubMedID: 9585291

Title : Effects of local cholinesterase inhibition on acetylcholine release assessed simultaneously in prefrontal and frontoparietal cortex - Himmelheber_1998_Neurosci_86_949
Author(s) : Himmelheber AM , Fadel J , Sarter M , Bruno JP
Ref : Neuroscience , 86 :949 , 1998
Abstract :
PubMedSearch : Himmelheber_1998_Neurosci_86_949
PubMedID: 9692730

Title : Mary B. Walker, M.D. and the pioneering use of prostigmin to treat myasthenia gravis - Keeney_1997_Doc.Ophthalmol_93_125
Author(s) : Keeney AH , Keeney VT
Ref : Doc Ophthalmol , 93 :125 , 1997
Abstract :
PubMedSearch : Keeney_1997_Doc.Ophthalmol_93_125
PubMedID: 9476610

Title : Studies on the safety of glucose and paraben-containing neostigmine for intrathecal administration - Gurun_1997_Anesth.Analg_85_317
Author(s) : Gurun MS , Leinbach R , Moore L , Lee CS , Owen MD , Eisenach JC
Ref : Anesthesia & Analgesia , 85 :317 , 1997
Abstract :
PubMedSearch : Gurun_1997_Anesth.Analg_85_317
PubMedID: 9249107

Title : High dose neostigmine treatment of malignant sinus tachycardia - Schultheis_1997_Pacing.Clin.Electrophysiol_20_1369
Author(s) : Schultheis LW , Balser JR , Calkins H , Robertson S , Weiss JL , Sussman M , Stuart RS
Ref : Pacing Clin Electrophysiol , 20 :1369 , 1997
Abstract :
PubMedSearch : Schultheis_1997_Pacing.Clin.Electrophysiol_20_1369
PubMedID: 9170142

Title : Intrathecal neostigmine for post-cesarean section analgesia: dose response - Krukowski_1997_Anesth.Analg_84_1269
Author(s) : Krukowski JA , Hood DD , Eisenach JC , Mallak KA , Parker RL
Ref : Anesthesia & Analgesia , 84 :1269 , 1997
Abstract :
PubMedSearch : Krukowski_1997_Anesth.Analg_84_1269
PubMedID: 9174305

Title : Factors affecting neostigmine reversal of vecuronium block during sevoflurane anaesthesia - Morita_1997_Anaesthesia_52_538
Author(s) : Morita T , Kurosaki D , Tsukagoshi H , Shimada H , Sato H , Goto F
Ref : Anaesthesia , 52 :538 , 1997
Abstract :
PubMedSearch : Morita_1997_Anaesthesia_52_538
PubMedID: 9203879

Title : Postoperative analgesic effect of intrathecal neostigmine and its influence on spinal anaesthesia - Klamt_1997_Anaesthesia_52_547
Author(s) : Klamt JG , Slullitel A , Garcia IV , Prado WA
Ref : Anaesthesia , 52 :547 , 1997
Abstract :
PubMedSearch : Klamt_1997_Anaesthesia_52_547
PubMedID: 9203881

Title : Antinociceptive effect of intrathecal neostigmine evaluated in rats by two different pain models - Prado_1997_Braz.J.Med.Biol.Res_30_1225
Author(s) : Prado WA , Goncalves AS
Ref : Brazilian Journal of Medical & Biological Research , 30 :1225 , 1997
Abstract :
PubMedSearch : Prado_1997_Braz.J.Med.Biol.Res_30_1225
PubMedID: 9496442

Title : Effect of glyceryl trinitrate on the sphincter of Oddi spasm evoked by prostigmine-morphine administration - Velosy_1997_Eur.J.Gastroenterol.Hepatol_9_1109
Author(s) : Velosy B , Madacsy L , Lonovics J , Csernay L
Ref : European Journal of Gastroenterology & Hepatology , 9 :1109 , 1997
Abstract :
PubMedSearch : Velosy_1997_Eur.J.Gastroenterol.Hepatol_9_1109
PubMedID: 9431903

Title : Cholinesterase activity in human pulmonary arteries and veins - Walch_1997_Br.J.Pharmacol_121_986
Author(s) : Walch L , Taisne C , Gascard JP , Nashashibi N , Brink C , Norel X
Ref : British Journal of Pharmacology , 121 :986 , 1997
Abstract :
PubMedSearch : Walch_1997_Br.J.Pharmacol_121_986
PubMedID: 9222557

Title : Recovery from mivacurium block with or without anticholinesterase following continuous infusion in obstetric patients - Jan_1996_Anaesth.Intensive.Care_24_585
Author(s) : Jan GS , Tong WN , Chan AM , Hui TW , Lo JW
Ref : Anaesthesia & Intensive Care , 24 :585 , 1996
Abstract :
PubMedSearch : Jan_1996_Anaesth.Intensive.Care_24_585
PubMedID: 8909671

Title : Neostigmine but not edrophonium prolongs the action of mivacurium - Symington_1996_Can.J.Anaesth_43_1220
Author(s) : Symington MJ , Mirakhur RK , Kumar N
Ref : Canadian Journal of Anaesthesia , 43 :1220 , 1996
Abstract :
PubMedSearch : Symington_1996_Can.J.Anaesth_43_1220
PubMedID: 8955970

Title : Pseudocholinesterase-mediated hydrolysis is superior to neostigmine for reversal of mivacurium-induced paralysis in vitro - Yang_1996_Anesthesiology_84_936
Author(s) : Yang HS , Goudsouzian N , Martyn JA
Ref : Anesthesiology , 84 :936 , 1996
Abstract :
PubMedSearch : Yang_1996_Anesthesiology_84_936
PubMedID: 8638849

Title : Dose responses for neostigmine and edrophonium as antagonists of mivacurium in adults and children - Bevan_1996_Anesthesiology_84_354
Author(s) : Bevan JC , Tousignant C , Stephenson C , Blackman L , Reimer E , Smith MF , Bevan DR
Ref : Anesthesiology , 84 :354 , 1996
Abstract :
PubMedSearch : Bevan_1996_Anesthesiology_84_354
PubMedID: 8602666

Title : Anticholinesterase drugs stimulate phosphatidylinositol response in rat tracheal slices - Shibata_1996_Anesth.Analg_82_1211
Author(s) : Shibata O , Kanairo M , Zhang S , Hasuo H , Morooka H , Fujie T , Sumikawa K
Ref : Anesthesia & Analgesia , 82 :1211 , 1996
Abstract :
PubMedSearch : Shibata_1996_Anesth.Analg_82_1211
PubMedID: 8638793

Title : Different properties of the bradycardia produced by neostigmine and edrophonium in the cat - Backman_1996_Can.J.Anaesth_43_731
Author(s) : Backman SB , Stein RD , Blank DW , Collier B , Polosa C
Ref : Canadian Journal of Anaesthesia , 43 :731 , 1996
Abstract :
PubMedSearch : Backman_1996_Can.J.Anaesth_43_731
PubMedID: 8807181

Title : Neostigmine reversal of vecuronium neuromuscular block and the influence of renal failure - Dhonneur_1996_Anesth.Analg_82_134
Author(s) : Dhonneur G , Rebaine C , Slavov V , Ruggier R , De Chaubry V , Duvaldestin P
Ref : Anesthesia & Analgesia , 82 :134 , 1996
Abstract :
PubMedSearch : Dhonneur_1996_Anesth.Analg_82_134
PubMedID: 8712389

Title : Influence and relative sensitivities of 50-Hz and 100-Hz tetanic stimuli on subsequent tetanic fade ratios in patients receiving vecuronium - Baurain_1996_Anesth.Analg_82_139
Author(s) : Baurain MJ , Hoton F , Dernovoi BS , d'Hollander AA
Ref : Anesthesia & Analgesia , 82 :139 , 1996
Abstract :
PubMedSearch : Baurain_1996_Anesth.Analg_82_139
PubMedID: 8712390

Title : Neostigmine for the treatment of neurotoxicity following envenomation by the Asiatic cobra - Gold_1996_Annals.of.Emergency.Medicine_28_87
Author(s) : Gold BS
Ref : Annals of Emergency Medicine , 28 :87 , 1996
Abstract :
PubMedSearch : Gold_1996_Annals.of.Emergency.Medicine_28_87
PubMedID: 8669746

Title : Neostigmine decreases heart rate in heart transplant patients - Backman_1996_Can.J.Anaesth_43_373
Author(s) : Backman SB , Fox GS , Stein RD , Ralley FE
Ref : Canadian Journal of Anaesthesia , 43 :373 , 1996
Abstract :
PubMedSearch : Backman_1996_Can.J.Anaesth_43_373
PubMedID: 8697553

Title : Neostigmine-induced bradycardia following recent vs remote cardiac transplantation in the same patient - Backman_1996_Can.J.Anaesth_43_394
Author(s) : Backman SB , Stein RD , Ralley FE , Fox GS
Ref : Canadian Journal of Anaesthesia , 43 :394 , 1996
Abstract :
PubMedSearch : Backman_1996_Can.J.Anaesth_43_394
PubMedID: 8697556

Title : Neostigmine in the treatment of snake accidents caused by Micrurus frontalis: report of two cases (1) - Vital_1996_Rev.Inst.Med.Trop.Sao.Paulo_38_61
Author(s) : Vital Brazil O , Vieira RJ
Ref : Revista do Instituto de Medicina Tropical de Sao Paulo , 38 :61 , 1996
Abstract :
PubMedSearch : Vital_1996_Rev.Inst.Med.Trop.Sao.Paulo_38_61
PubMedID: 8762642

Title : Interaction between intrathecal neostigmine and epidural clonidine in human volunteers - Hood_1996_Anesthesiology_85_315
Author(s) : Hood DD , Mallak KA , Eisenach JC , Tong C
Ref : Anesthesiology , 85 :315 , 1996
Abstract :
PubMedSearch : Hood_1996_Anesthesiology_85_315
PubMedID: 8712447

Title : Do we need anti snake venom (ASV) for management of elapid ophitoxaemia - Bomb_1996_Journal.of.the.Association.of.Physicians.of.India_44_31
Author(s) : Bomb BS , Roy S , Kumawat DC , Bharjatya M
Ref : Journal of the Association of Physicians of India , 44 :31 , 1996
Abstract :
PubMedSearch : Bomb_1996_Journal.of.the.Association.of.Physicians.of.India_44_31
PubMedID: 8773091

Title : Conditions to optimise the reversal action of neostigmine upon a vecuronium-induced neuromuscular block - Baurain_1996_Acta.Anaesthesiol.Scand_40_574
Author(s) : Baurain MJ , Dernovoi BS , d'Hollander AA , Hennart DA , Cantraine FR
Ref : Acta Anaesthesiologica Scandinavica , 40 :574 , 1996
Abstract :
PubMedSearch : Baurain_1996_Acta.Anaesthesiol.Scand_40_574
PubMedID: 8792887

Title : Optimum time for neostigmine reversal of atracurium-induced neuromuscular blockade - Kirkegaard-Nielsen_1996_Can.J.Anaesth_43_932
Author(s) : Kirkegaard-Nielsen H , Helbo-Hansen HS , Lindholm P , Severinsen IK , Pedersen HS , Jensen EW
Ref : Canadian Journal of Anaesthesia , 43 :932 , 1996
Abstract :
PubMedSearch : Kirkegaard-Nielsen_1996_Can.J.Anaesth_43_932
PubMedID: 8874911

Title : Additives in neuraxial anesthesia: opioids, alpha-2 adrenergic agonists, and neostigmine as a possible future drug for perioperative pain management -
Author(s) : Klimscha W , Chiari A , Lorber C , Krenn K , Dumitrescu R , Agnese T
Ref : Acta Anaesthesiologica Scandinavica Supplementum , 109 :176 , 1996
PubMedID: 8901999

Title : Is recovery of neuromuscular transmission complete after the use of neostigmine to antagonize block produced by rocuronium, vecuronium, atracurium and pancuronium? - Baurain_1996_Br.J.Anaesth_77_496
Author(s) : Baurain MJ , Hoton F , d'Hollander AA , Cantraine FR
Ref : British Journal of Anaesthesia , 77 :496 , 1996
Abstract :
PubMedSearch : Baurain_1996_Br.J.Anaesth_77_496
PubMedID: 8942335

Title : Dose-response relationships for neostigmine antagonism of rocuronium-induced neuromuscular block in children and adults - Abdulatif_1996_Br.J.Anaesth_77_710
Author(s) : Abdulatif M , Mowafi H , Al-Ghamdi A , el-Sanabary M
Ref : British Journal of Anaesthesia , 77 :710 , 1996
Abstract :
PubMedSearch : Abdulatif_1996_Br.J.Anaesth_77_710
PubMedID: 9014620

Title : Effect of neostigmine at different levels of mivacurium-induced neuromuscular blockade - Trevien_1995_Acta.Anaesth.Scand.Supplementum_106_66
Author(s) : Trevien V , Lienhart A , Just B , Chandon M , Baras E , Camatte S
Ref : Acta Anaesthesiologica Scandinavica Supplementum , 106 :66 , 1995
Abstract :
PubMedSearch : Trevien_1995_Acta.Anaesth.Scand.Supplementum_106_66
PubMedID: 8533550

Title : Comparison of the effects of neostigmine and edrophonium on the duration of action of suxamethonium - McCoy_1995_Acta.Anaesthesiol.Scand_39_744
Author(s) : McCoy EP , Mirakhur RK
Ref : Acta Anaesthesiologica Scandinavica , 39 :744 , 1995
Abstract :
PubMedSearch : McCoy_1995_Acta.Anaesthesiol.Scand_39_744
PubMedID: 7484027

Title : [Neurotoxic effects of cobra venom (Naja haje haje) on the neuromuscular junction. Electroclinical study of two cases in Tunisia]. [French] - Zouari_1995_Neurophysiologie.Clinique_25_59
Author(s) : Zouari N , Choyakh F
Ref : Neurophysiologie Clinique , 25 :59 , 1995
Abstract :
PubMedSearch : Zouari_1995_Neurophysiologie.Clinique_25_59
PubMedID: 7603413

Title : Ventilatory muscle strength and endurance in myasthenia gravis - Keenan_1995_Eur.Respir.J_8_1130
Author(s) : Keenan SP , Alexander D , Road JD , Ryan CF , Oger J , Wilcox PG
Ref : European Respiratory Journal , 8 :1130 , 1995
Abstract :
PubMedSearch : Keenan_1995_Eur.Respir.J_8_1130
PubMedID: 7589397

Title : Endogenous acetylcholine-induced Fos expression in magnocellular neurosecretory neurons in the supraoptic nucleus of the rat hypothalamus - Shen_1995_Neurosci.Lett_195_191
Author(s) : Shen E , Sun X
Ref : Neuroscience Letters , 195 :191 , 1995
Abstract :
PubMedSearch : Shen_1995_Neurosci.Lett_195_191
PubMedID: 8584207

Title : Effect of bethanechol, neostigmine, metoclopramide, and propranolol on myoelectric activity of the ileocecocolic area in cows - Steiner_1995_Am.J.Vet.Res_56_1081
Author(s) : Steiner A , Roussel AJ , Martig J
Ref : American Journal of Veterinary Research , 56 :1081 , 1995
Abstract :
PubMedSearch : Steiner_1995_Am.J.Vet.Res_56_1081
PubMedID: 8533981

Title : Optimum time for neostigmine administration to antagonize vecuronium-induced neuromuscular blockade - Kirkegaard-Nielsen_1995_Eur.J.Anaesthesiol_12_585
Author(s) : Kirkegaard-Nielsen H , Toft P , Severinsen IK , May O
Ref : European Journal of Anaesthesiology , 12 :585 , 1995
Abstract :
PubMedSearch : Kirkegaard-Nielsen_1995_Eur.J.Anaesthesiol_12_585
PubMedID: 8665881

Title : The effect of reversal of myoneural blockade on cerebrospinal fluid pressure following cerebral aneurysm surgery - Fawcett_1995_Eur.J.Anaesthesiol_12_591
Author(s) : Fawcett WJ , Chung RA , Fairley CJ , Hollway TE
Ref : European Journal of Anaesthesiology , 12 :591 , 1995
Abstract :
PubMedSearch : Fawcett_1995_Eur.J.Anaesthesiol_12_591
PubMedID: 8665882

Title : Time to peak effect of neostigmine at antagonism of atracurium- or vecuronium-induced neuromuscular block - Kirkegaard-Nielsen_1995_J.Clin.Anesth_7_635
Author(s) : Kirkegaard-Nielsen H , Helbo-Hansen HS , Lindholm P , Severinsen IK , Bulow K
Ref : Journal of Clinical Anesthesia , 7 :635 , 1995
Abstract :
PubMedSearch : Kirkegaard-Nielsen_1995_J.Clin.Anesth_7_635
PubMedID: 8747561

Title : Comparative pharmacokinetics of four cholinesterase inhibitors in rats - Yamamoto_1995_Biol.Pharm.Bull_18_1292
Author(s) : Yamamoto K , Sawada Y , Iga T
Ref : Biol Pharm Bull , 18 :1292 , 1995
Abstract :
PubMedSearch : Yamamoto_1995_Biol.Pharm.Bull_18_1292
PubMedID: 8845827

Title : The timing of channel opening during miniature endplate currents at the frog and mouse neuromuscular junctions: effects of fasciculin-2, other anti-cholinesterases and vesamicol - Van der Kloot_1994_Pflugers.Arch_428_114
Author(s) : Van der Kloot W , Balezina OP , Molgo J , Naves LA
Ref : Pflugers Arch , 428 :114 , 1994
Abstract :
PubMedSearch : Van der Kloot_1994_Pflugers.Arch_428_114
PubMedID: 7971167

Title : Degradation of acetylcholine in human airways: role of butyrylcholinesterase - Norel_1993_Br.J.Pharmacol_108_914
Author(s) : Norel X , Angrisani M , Labat C , Gorenne I , Dulmet E , Rossi F , Brink C
Ref : British Journal of Pharmacology , 108 :914 , 1993
Abstract :
PubMedSearch : Norel_1993_Br.J.Pharmacol_108_914
PubMedID: 8485630

Title : In vitro protection of acetylcholinesterase and butyrylcholinesterase by tetrahydroaminoacridine. Comparison with physostigmine - Galli_1992_Biochem.Pharmacol_43_2427
Author(s) : Galli A , Mori F , Gori I , Lucherini M
Ref : Biochemical Pharmacology , 43 :2427 , 1992
Abstract :
PubMedSearch : Galli_1992_Biochem.Pharmacol_43_2427
PubMedID: 1610407

Title : Genetic variants of human serum cholinesterase influence metabolism of the muscle relaxant succinylcholine. - Lockridge_1990_Pharmacol.Ther_47_35
Author(s) : Lockridge O
Ref : Pharmacol Ther , 47 :35 , 1990
Abstract :
PubMedSearch : Lockridge_1990_Pharmacol.Ther_47_35
PubMedID: 2195556
Gene_locus related to this paper: human-BCHE

Title : A peptidase activity exhibited by human serum pseudocholinesterase - Boopathy_1987_Eur.J.Biochem_162_191
Author(s) : Boopathy R , Balasubramanian AS
Ref : European Journal of Biochemistry , 162 :191 , 1987
Abstract :
PubMedSearch : Boopathy_1987_Eur.J.Biochem_162_191
PubMedID: 3545820

Title : In-vitro and in-vivo protection of acetylcholinesterase by eseroline against inactivation by diisopropyl fluorophosphate and carbamates - Galli_1985_J.Pharm.Pharmacol_37_42
Author(s) : Galli A , Malmberg-Aiello P , Renzi G , Bartolini A
Ref : J Pharm Pharmacol , 37 :42 , 1985
Abstract :
PubMedSearch : Galli_1985_J.Pharm.Pharmacol_37_42
PubMedID: 2858526

Title : Activation and blockade of cardiac muscarinic receptors by endogenous acetylcholine and cholinesterase inhibitors - Brown_1982_J.Pharmacol.Exp.Ther_223_20
Author(s) : Brown JH , Wetzel GT , Dunlap J
Ref : Journal of Pharmacology & Experimental Therapeutics , 223 :20 , 1982
Abstract :
PubMedSearch : Brown_1982_J.Pharmacol.Exp.Ther_223_20
PubMedID: 6288918

Title : Inhibition of human motor endplate cholinesterase by anticholinesterase compounds - Fujii_1982_Acta.Med.Okayama_36_229
Author(s) : Fujii M , Namba T
Ref : Acta Med Okayama , 36 :229 , 1982
Abstract :
PubMedSearch : Fujii_1982_Acta.Med.Okayama_36_229
PubMedID: 7113748

Title : The aryl acylamidases and their relationship to cholinesterases in human serum, erythrocyte and liver - George_1981_Eur.J.Biochem_121_177
Author(s) : George ST , Balasubramanian AS
Ref : European Journal of Biochemistry , 121 :177 , 1981
Abstract :
PubMedSearch : George_1981_Eur.J.Biochem_121_177
PubMedID: 7035166

Title : Differential inhibition of plasma cholinesterase variants using the dibutyrate analogue of pancuronium bromide - Whittaker_1981_Hum.Hered_31_242
Author(s) : Whittaker M , Britten JJ
Ref : Hum Hered , 31 :242 , 1981
Abstract :
PubMedSearch : Whittaker_1981_Hum.Hered_31_242
PubMedID: 7287015

Title : The identity of the serotonin-sensitive aryl acylamidase with acetylcholinesterase from human erythrocytes, sheep basal ganglia and electric eel - George_1980_Eur.J.Biochem_111_511
Author(s) : George ST , Balasubramanian AS
Ref : European Journal of Biochemistry , 111 :511 , 1980
Abstract :
PubMedSearch : George_1980_Eur.J.Biochem_111_511
PubMedID: 7460914

Title : The inhibition of frog tissue cholinesterases and the influence of eserine and prostigmine on the action of acetylcholine on the frog heart - Majcen_1975_Biochem.Pharmacol_24_1599
Author(s) : Majcen Z , Brzin M
Ref : Biochemical Pharmacology , 24 :1599 , 1975
Abstract :
PubMedSearch : Majcen_1975_Biochem.Pharmacol_24_1599
PubMedID: 1081394

Title : The activity of various esterase inhibitors towards atypical human serum cholinesterase -
Author(s) : Kalow W , Davies R0
Ref : Biochemical Pharmacology , 1 :183 , 1958
PubMedID:

Title : Case showing effect of prostigmin on myasthenia gravis -
Author(s) : Walker MB
Ref : Proc Roy Soc Med , 28 :759 , 1935
PubMedID: 19990268