DGDG

human-PNLIPRP2 adopt in solution an open lid conformation which creates a large cavity capable of accommodating the galactose polar head of galactolipids

General

Type : Acyl-Glycerol, Diacylglycerol, Galactolipid, Glycosydiacylglycerol, Glycoside, Dodecanoate

Chemical_Nomenclature : 3-O-(6-O-R-D-galactopyranosyl-beta-D-galactopyranosyl)-1,2-di-O-dodecanoyl-sn-gycerol

Canonical SMILES :

InChI :

InChIKey :

Other name(s) : DiC8-DGDG


MW : 780.98

Formula : C39H72O15

CAS_number :

PubChem :

UniChem :

Wikipedia : Galactolipid

Target

Structures : No structure

Families : Pancreatic_lipase, Lipase_3, Insect_lipase, Plant_phospholipase

References (13)

Title : The digestion of galactolipids and its ubiquitous function in Nature for the uptake of the essential alpha-linolenic acid - Sahaka_2020_Food.Funct_11_6710
Author(s) : Sahaka M , Amara S , Wattanakul J , Gedi MA , Aldai N , Parsiegla G , Lecomte J , Christeller JT , Gray D , Gontero B , Villeneuve P , Carriere F
Ref : Food Funct , 11 :6710-6744 , 2020
Abstract :
PubMedSearch : Sahaka_2020_Food.Funct_11_6710
PubMedID: 32687132
Gene_locus related to this paper: helam-a0a2w1b5z2 , cavpo-2plrp

Title : Galactolipase activity of Talaromyces thermophilus lipase on galactolipid micelles, monomolecular films and UV-absorbing surface-coated substrate - Belhaj_2018_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1863_1006
Author(s) : Belhaj I , Amara S , Parsiegla G , Sutto-Ortiz P , Sahaka M , Belghith H , Rousset A , Lafont D , Carriere F
Ref : Biochimica & Biophysica Acta Molecular & Cellular Biology Lipids , 1863 :1006 , 2018
Abstract :
PubMedSearch : Belhaj_2018_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1863_1006
PubMedID: 29859246
Gene_locus related to this paper: talth-f6lqk7

Title : The beta5-Loop and Lid Domain Contribute to the Substrate Specificity of Pancreatic Lipase-related Protein 2 (PNLIPRP2) - Xiao_2015_J.Biol.Chem_290_28847
Author(s) : Xiao X , Lowe ME
Ref : Journal of Biological Chemistry , 290 :28847 , 2015
Abstract :
PubMedSearch : Xiao_2015_J.Biol.Chem_290_28847
PubMedID: 26494624
Gene_locus related to this paper: human-PNLIP , human-PNLIPRP2

Title : The galactolipase activity of Fusarium solani (phospho)lipase - Jallouli_2015_Biochim.Biophys.Acta_1851_282
Author(s) : Jallouli R , Othman H , Amara S , Parsiegla G , Carriere F , Srairi-Abid N , Gargouri Y , Bezzine S
Ref : Biochimica & Biophysica Acta , 1851 :282 , 2015
Abstract :
PubMedSearch : Jallouli_2015_Biochim.Biophys.Acta_1851_282
PubMedID: 25529980
Gene_locus related to this paper: nech7-c7yuz1

Title : Lipolysis of natural long chain and synthetic medium chain galactolipids by pancreatic lipase-related protein 2 - Amara_2010_Biochim.Biophys.Acta_1801_508
Author(s) : Amara S , Barouh N , Lecomte J , Lafont D , Robert S , Villeneuve P , de Caro A , Carriere F
Ref : Biochimica & Biophysica Acta , 1801 :508 , 2010
Abstract :
PubMedSearch : Amara_2010_Biochim.Biophys.Acta_1801_508
PubMedID: 20083229
Gene_locus related to this paper: human-PNLIPRP2

Title : Continuous measurement of galactolipid hydrolysis by pancreatic lipolytic enzymes using the pH-stat technique and a medium chain monogalactosyl diglyceride as substrate - Amara_2009_Biochim.Biophys.Acta_1791_983
Author(s) : Amara S , Lafont D , Fiorentino B , Boullanger P , Carriere F , de Caro A
Ref : Biochimica & Biophysica Acta , 1791 :983 , 2009
Abstract :
PubMedSearch : Amara_2009_Biochim.Biophys.Acta_1791_983
PubMedID: 19447192
Gene_locus related to this paper: cavpo-2plrp , human-PNLIPRP2

Title : Modulating pancreatic lipase activity with galactolipids: effects of emulsion interfacial composition - Chu_2009_Langmuir_25_9352
Author(s) : Chu BS , Rich GT , Ridout MJ , Faulks RM , Wickham MS , Wilde PJ
Ref : Langmuir , 25 :9352 , 2009
Abstract :
PubMedSearch : Chu_2009_Langmuir_25_9352
PubMedID: 19438174

Title : Cooperation and functional diversification of two closely related galactolipase genes for jasmonate biosynthesis - Hyun_2008_Dev.Cell_14_183
Author(s) : Hyun Y , Choi S , Hwang HJ , Yu J , Nam SJ , Ko J , Park JY , Seo YS , Kim EY , Ryu SB , Kim WT , Lee YH , Kang H , Lee I
Ref : Dev Cell , 14 :183 , 2008
Abstract :
PubMedSearch : Hyun_2008_Dev.Cell_14_183
PubMedID: 18267087
Gene_locus related to this paper: arath-AT4G16820 , arath-PLA11 , arath-PLA12 , arath-PLA13 , arath-PLA15 , arath-PLA16 , arath-PLA17

Title : Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation - Eydoux_2008_Biochemistry_47_9553
Author(s) : Eydoux C , Spinelli S , Davis TL , Walker JR , Seitova A , Dhe-Paganon S , de Caro A , Cambillau C , Carriere F
Ref : Biochemistry , 47 :9553 , 2008
Abstract :
PubMedSearch : Eydoux_2008_Biochemistry_47_9553
PubMedID: 18702514
Gene_locus related to this paper: human-PNLIPRP2

Title : Further biochemical characterization of human pancreatic lipase-related protein 2 expressed in yeast cells - Eydoux_2007_J.Lipid.Res_48_1539
Author(s) : Eydoux C , De Caro J , Ferrato F , Boullanger P , Lafont D , Laugier R , Carriere F , de Caro A
Ref : J Lipid Res , 48 :1539 , 2007
Abstract :
PubMedSearch : Eydoux_2007_J.Lipid.Res_48_1539
PubMedID: 17401110
Gene_locus related to this paper: human-PNLIPRP2

Title : Chemoenzymatic synthesis and in vitro studies on the hydrolysis of antimicrobial monoglycosyl diglycerides by pancreatic lipase - Cateni_2007_Bioorg.Med.Chem.Lett_17_1971
Author(s) : Cateni F , Bonivento P , Procida G , Zacchigna M , Scialino G , Banfi E
Ref : Bioorganic & Medicinal Chemistry Lett , 17 :1971 , 2007
Abstract :
PubMedSearch : Cateni_2007_Bioorg.Med.Chem.Lett_17_1971
PubMedID: 17270436

Title : Syntheses of an alpha-D-Gal-(1-->6)-beta-D-Gal diglyceride, as lipase substrate - Lafont_2006_Carbohydr.Res_341_695
Author(s) : Lafont D , Carriere F , Ferrato F , Boullanger P
Ref : Carbohydr Res , 341 :695 , 2006
Abstract :
PubMedSearch : Lafont_2006_Carbohydr.Res_341_695
PubMedID: 16458274

Title : Pancreatic lipase-related protein 2 but not classical pancreatic lipase hydrolyzes galactolipids - Andersson_1996_Biochim.Biophys.Acta_1302_236
Author(s) : Andersson L , Carriere F , Lowe ME , Nilsson A , Verger R
Ref : Biochimica & Biophysica Acta , 1302 :236 , 1996
Abstract :
PubMedSearch : Andersson_1996_Biochim.Biophys.Acta_1302_236
PubMedID: 8765145