Octanoyl-ghrelin

General

Type : Acyl peptide

Chemical_Nomenclature : octanoyl ghrelin\; [O-n-octanoyl-Ser3]-human ghrelin

Canonical SMILES :

InChI :

InChIKey : BGHSOEHUOOAYMY-JTZMCQEISA-N

Other name(s) : Acyl-ghrelin  ||  Gastric MLTRP  ||  Motilin-related peptide  ||  Human ghrelin  ||  [Des-octanoyl]-Ghrelin (human)


MW :

Formula :

CAS_number :

PubChem :

UniChem : BGHSOEHUOOAYMY-JTZMCQEISA-N

Wikipedia : Ghrelin

Target

Structures : 6ZYF

Families : BCHE, Pectinacetylesterase-Notum

References (13)

Title : Notum Deacylates Octanoylated Ghrelin - Zhao_2021_Mol.Metab__101201
Author(s) : Zhao Y , Schuhmacher LN , Roberts M , Kakugawa S , Bineva-Todd G , Howell S , O'Reilly N , Perret C , Snijders AP , Vincent JP , Jones EY
Ref : Mol Metab , :101201 , 2021
Abstract :
PubMedSearch : Zhao_2021_Mol.Metab__101201
PubMedID: 33647468
Gene_locus related to this paper: human-NOTUM

Title : Ghrelin Octanoylation Is Completely Stabilized in Biological Samples by Alkyl Fluorophosphonates - McGovern-Gooch_2016_Endocrinology_157_4330
Author(s) : McGovern-Gooch KR , Rodrigues T , Darling JE , Sieburg MA , Abizaid A , Hougland JL
Ref : Endocrinology , 157 :4330 , 2016
Abstract :
PubMedSearch : McGovern-Gooch_2016_Endocrinology_157_4330
PubMedID: 27623288

Title : Plasma butyrylcholinesterase regulates ghrelin to control aggression - Chen_2015_Proc.Natl.Acad.Sci.U.S.A_112_2251
Author(s) : Chen VP , Gao Y , Geng L , Parks RJ , Pang YP , Brimijoin S
Ref : Proc Natl Acad Sci U S A , 112 :2251 , 2015
Abstract :
PubMedSearch : Chen_2015_Proc.Natl.Acad.Sci.U.S.A_112_2251
PubMedID: 25646463

Title : Kinetic characterization of a cocaine hydrolase engineered from mouse butyrylcholinesterase - Chen_2015_Biochem.J_466_243
Author(s) : Chen X , Huang X , Geng L , Xue L , Hou S , Zheng X , Brimijoin S , Zheng F , Zhan CG
Ref : Biochemical Journal , 466 :243 , 2015
Abstract :
PubMedSearch : Chen_2015_Biochem.J_466_243
PubMedID: 25486543
Gene_locus related to this paper: human-BCHE

Title : Pure human butyrylcholinesterase hydrolyzes octanoyl ghrelin to desacyl ghrelin - Schopfer_2015_Gen.Comp.Endocrinol_224_61
Author(s) : Schopfer LM , Lockridge O , Brimijoin S
Ref : General & Comparative Endocrinology , 224 :61 , 2015
Abstract :
PubMedSearch : Schopfer_2015_Gen.Comp.Endocrinol_224_61
PubMedID: 26073531

Title : Radiometric assay of ghrelin hydrolase activity and (3)H-ghrelin distribution into mouse tissues - Chen_2015_Biochem.Pharmacol_98_732
Author(s) : Chen VP , Gao Y , Geng L , Brimijoin S
Ref : Biochemical Pharmacology , 98 :732 , 2015
Abstract :
PubMedSearch : Chen_2015_Biochem.Pharmacol_98_732
PubMedID: 26514871

Title : Obesity and variants of the GHRL (ghrelin) and BCHE (butyrylcholinesterase) genes - Dantas_2011_Genet.Mol.Biol_34_205
Author(s) : Dantas VG , Furtado-Alle L , de Souza RLR , Chautard-Freire-Maia EA
Ref : Genet Mol Biol , 34 :205 , 2011
Abstract :
PubMedSearch : Dantas_2011_Genet.Mol.Biol_34_205
PubMedID: 21734817

Title : High-fat diet with acyl-ghrelin treatment leads to weight gain with low inflammation, high oxidative capacity and normal triglycerides in rat muscle - Barazzoni_2011_PLoS.One_6_e26224
Author(s) : Barazzoni R , Zanetti M , Semolic A , Cattin MR , Pirulli A , Cattin L , Guarnieri G
Ref : PLoS ONE , 6 :e26224 , 2011
Abstract :
PubMedSearch : Barazzoni_2011_PLoS.One_6_e26224
PubMedID: 22039445

Title : Ghrelin octanoylation mediated by an orphan lipid transferase - Gutierrez_2008_Proc.Natl.Acad.Sci.U.S.A_105_6320
Author(s) : Gutierrez JA , Solenberg PJ , Perkins DR , Willency JA , Knierman MD , Jin Z , Witcher DR , Luo S , Onyia JE , Hale JE
Ref : Proc Natl Acad Sci U S A , 105 :6320 , 2008
Abstract :
PubMedSearch : Gutierrez_2008_Proc.Natl.Acad.Sci.U.S.A_105_6320
PubMedID: 18443287

Title : The butyrylcholinesterase knockout mouse is obese on a high-fat diet - Li_2008_Chem.Biol.Interact_175_88
Author(s) : Li B , Duysen EG , Lockridge O
Ref : Chemico-Biological Interactions , 175 :88 , 2008
Abstract :
PubMedSearch : Li_2008_Chem.Biol.Interact_175_88
PubMedID: 18452903

Title : A medical health report on individuals with silent butyrylcholinesterase in the Vysya community of India - Manoharan_2007_Clin.Chim.Acta_378_128
Author(s) : Manoharan I , Boopathy R , Darvesh S , Lockridge O
Ref : Clinica Chimica Acta , 378 :128 , 2007
Abstract :
PubMedSearch : Manoharan_2007_Clin.Chim.Acta_378_128
PubMedID: 17182021

Title : Ghrelin interacts with human plasma lipoproteins - De Vriese_2007_Endocrinology_148_2355
Author(s) : De Vriese C , Hacquebard M , Gregoire F , Carpentier Y , Delporte C
Ref : Endocrinology , 148 :2355 , 2007
Abstract :
PubMedSearch : De Vriese_2007_Endocrinology_148_2355
PubMedID: 17289852

Title : Ghrelin degradation by serum and tissue homogenates: identification of the cleavage sites - De Vriese_2004_Endocrinology_145_4997
Author(s) : De Vriese C , Gregoire F , Lema-Kisoka R , Waelbroeck M , Robberecht P , Delporte C
Ref : Endocrinology , 145 :4997 , 2004
Abstract :
PubMedSearch : De Vriese_2004_Endocrinology_145_4997
PubMedID: 15256494