porgi-DPP
Porphyromonas gingivalis (Bacteroides gingivalis) dipeptidyl peptidase IV
Comment
Other strains: Porphyromonas gingivalis (strain ATCC 33277 \/ DSM 20709 \/ JCM 12257)
Relationship
Family : DPP4N_Peptidase_S9
Block : X
Position in NCBI Life Tree : Porphyromonas gingivalis
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Bacteria N E > FCB group N E > Bacteroidetes\/Chlorobi group N E > Bacteroidetes N E > Bacteroidia N E > Bacteroidales N E > Porphyromonadaceae N E > Porphyromonas N E > Porphyromonas gingivalis N EMolecular evidence
Sequence
Peptide
MKRPVIILLL GIVTMCAMAQ TGDKPVDLKE ITSGMFYARS AGRGIRSMPD GEHYTEMNRE RTAIVRYNYA SGKAVDTLFS VERARECPFK QIQNYEVSST GHHILLFTDM ESIYRHSYRA AVYDYDVRRN LVKPLSEHVG KVMIPTFSPD GRMVAFVRDN NIFIKKFDFD TEVQVTTDGQ INSILNGATD WVYEEEFGVT NLMSWSADNA FLAFVRSDES AVPEYRMPMY EDKIYPEDYT YKYPKAGEKN STVSLHLYNV ADRNTKSVSL PIDADGYIPR IAFTDNADEL AVMTLNRLQN DFKMYYVHPK SLVAKLILQD MNKRYVDSDW IQALKFTAGG GFAYVSEKDG FAHIYLYDNK GVMHRRITSG NWDVTKLYGV DASGTVFYQS AEESPIRRAV YAIDAKGRKT KLSLNVGTND ALFSGNYAYY INTYSSAATP TVVSVFRSKD AKELRTLEDN VALRERLKAY RYNPKEFTII KTQSGLELNA WIVKPIDFDP SRHYPVLMVQ YSGPNSQQVL DRYSFDWEHY LASKGYVVAC VDGRGTGARG EEWRKCTYMQ LGVFESDDQI AAATAIGQLP YVDAARIGIW GWSYGGYTTL MSLCRGNGTF KAGIAVAPVA DWRFYDSVYT ERFMRTPKEN ASGYKMSSAL DVASQLQGNL LIVSGSADDN VHLQNTMLFT EALVQANIPF DMAIYMDKNH SIYGGNTRYH LYIRKAKFLF DNL
References (6)
| Title : Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4 and structure-activity relationships based on inhibitor profiling - Rea_2017_Eur.J.Med.Chem_139_482 |
| Author(s) : Rea D , Van Elzen R , De Winter H , Van Goethem S , Landuyt B , Luyten W , Schoofs L , Van der Veken P , Augustyns K , De Meester I , Fulop V , Lambeir AM |
| Ref : Eur Journal of Medicinal Chemistry , 139 :482 , 2017 |
| Abstract : |
| PubMedSearch : Rea_2017_Eur.J.Med.Chem_139_482 |
| PubMedID: 28826083 |
| Gene_locus related to this paper: porgi-DPP |
| Title : Determination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalis - Naito_2008_DNA.Res_15_215 |
| Author(s) : Naito M , Hirakawa H , Yamashita A , Ohara N , Shoji M , Yukitake H , Nakayama K , Toh H , Yoshimura F , Kuhara S , Hattori M , Hayashi T |
| Ref : DNA Research , 15 :215 , 2008 |
| Abstract : |
| PubMedSearch : Naito_2008_DNA.Res_15_215 |
| PubMedID: 18524787 |
| Gene_locus related to this paper: porgi-DPP , porgi-q7mub3 , porgi-q7muw6 , porgi-q7mwa7 , porgi-q7mx03 |
| Title : Expression, purification and preliminary crystallographic analysis of dipeptidyl peptidase IV from Porphyromonas gingivalis - Rea_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1871 |
| Author(s) : Rea D , Lambeir AM , Kumagai Y , De Meester I , Scharpe S , Fulop V |
| Ref : Acta Crystallographica D Biol Crystallogr , 60 :1871 , 2004 |
| Abstract : |
| PubMedSearch : Rea_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1871 |
| PubMedID: 15388936 |
| Gene_locus related to this paper: porgi-DPP |
| Title : Complete genome sequence of the oral pathogenic Bacterium porphyromonas gingivalis strain W83 - Nelson_2003_J.Bacteriol_185_5591 |
| Author(s) : Nelson KE , Fleischmann RD , DeBoy RT , Paulsen IT , Fouts DE , Eisen JA , Daugherty SC , Dodson RJ , Durkin AS , Gwinn M , Haft DH , Kolonay JF , Nelson WC , Mason T , Tallon L , Gray J , Granger D , Tettelin H , Dong H , Galvin JL , Duncan MJ , Dewhirst FE , Fraser CM |
| Ref : Journal of Bacteriology , 185 :5591 , 2003 |
| Abstract : |
| PubMedSearch : Nelson_2003_J.Bacteriol_185_5591 |
| PubMedID: 12949112 |
| Gene_locus related to this paper: 9gamm-q4a538 , porgi-DPP , porgi-q7mtk3 , porgi-q7mu18 , porgi-q7mub3 , porgi-q7muw6 , porgi-q7mvp4 , porgi-q7mwa7 , porgi-q7mx03 |
| Title : Enzymatic properties of dipeptidyl aminopeptidase IV produced by the periodontal pathogen Porphyromonas gingivalis and its participation in virulence - Kumagai_2000_Infect.Immun_68_716 |
| Author(s) : Kumagai Y , Konishi K , Gomi T , Yagishita H , Yajima A , Yoshikawa M |
| Ref : Infect Immun , 68 :716 , 2000 |
| Abstract : |
| PubMedSearch : Kumagai_2000_Infect.Immun_68_716 |
| PubMedID: 10639438 |
| Gene_locus related to this paper: porgi-DPP |
| Title : Sequence analysis of the Porphyromonas gingivalis dipeptidyl peptidase IV gene - Kiyama_1998_Biochim.Biophys.Acta_1396_39 |
| Author(s) : Kiyama M , Hayakawa M , Shiroza T , Nakamura S , Takeuchi A , Masamoto Y , Abiko Y |
| Ref : Biochimica & Biophysica Acta , 1396 :39 , 1998 |
| Abstract : |
| PubMedSearch : Kiyama_1998_Biochim.Biophys.Acta_1396_39 |
| PubMedID: 9524216 |
| Gene_locus related to this paper: porgi-DPP |