| Title : Discovery of reversible monoacylglycerol lipase (MAGL) inhibitors based on ortho-hydroxyanilide scaffold - Bononi_2025_Bioorg.Chem_163_108698 |
| Author(s) : Bononi G , Gado F , Masoni S , Scalabrini D , Vedova LD , Di Stefano M , Piazza L , Poles C , Lonzi C , Landucci E , Vagaggini C , Poggialini F , Brai A , Caligiuri I , Rizzolio F , Mohamed KA , Bertini S , De Lorenzi E , Dreassi E , Macchia M , Minutolo F , Laprairie RB , Granchi C , Tuccinardi T |
| Ref : Bioorg Chem , 163 :108698 , 2025 |
| Abstract : |
| PubMedSearch : Bononi_2025_Bioorg.Chem_163_108698 |
| PubMedID: 40554889 |
| Gene_locus related to this paper: human-MGLL |
| Title : Methods for Assessing MAGL Enzymatic Activity: An Extensive Review of Past and Emerging Approaches - Bononi_2025_Int.J.Mol.Sci_26_9829 |
| Author(s) : Bononi G , Landucci E , Di Stefano M , Piazza L , Bertini S , Macchia M , Granchi C |
| Ref : Int J Mol Sci , 26 :9829 , 2025 |
| Abstract : |
| PubMedSearch : Bononi_2025_Int.J.Mol.Sci_26_9829 |
| PubMedID: 41097094 |
| Gene_locus related to this paper: human-MGLL |
| Title : Discovery of reversible monoacylglycerol lipase (MAGL) inhibitors based on ortho-hydroxyanilide scaffold - Bononi_2025_Bioorg.Chem_163_108698 |
| Author(s) : Bononi G , Gado F , Masoni S , Scalabrini D , Vedova LD , Di Stefano M , Piazza L , Poles C , Lonzi C , Landucci E , Vagaggini C , Poggialini F , Brai A , Caligiuri I , Rizzolio F , Mohamed KA , Bertini S , De Lorenzi E , Dreassi E , Macchia M , Minutolo F , Laprairie RB , Granchi C , Tuccinardi T |
| Ref : Bioorg Chem , 163 :108698 , 2025 |
| Abstract : |
| PubMedSearch : Bononi_2025_Bioorg.Chem_163_108698 |
| PubMedID: 40554889 |
| Gene_locus related to this paper: human-MGLL |
| Title : Methods for Assessing MAGL Enzymatic Activity: An Extensive Review of Past and Emerging Approaches - Bononi_2025_Int.J.Mol.Sci_26_9829 |
| Author(s) : Bononi G , Landucci E , Di Stefano M , Piazza L , Bertini S , Macchia M , Granchi C |
| Ref : Int J Mol Sci , 26 :9829 , 2025 |
| Abstract : |
| PubMedSearch : Bononi_2025_Int.J.Mol.Sci_26_9829 |
| PubMedID: 41097094 |
| Gene_locus related to this paper: human-MGLL |
| Title : Discovery of reversible monoacylglycerol lipase (MAGL) inhibitors based on ortho-hydroxyanilide scaffold - Bononi_2025_Bioorg.Chem_163_108698 |
| Author(s) : Bononi G , Gado F , Masoni S , Scalabrini D , Vedova LD , Di Stefano M , Piazza L , Poles C , Lonzi C , Landucci E , Vagaggini C , Poggialini F , Brai A , Caligiuri I , Rizzolio F , Mohamed KA , Bertini S , De Lorenzi E , Dreassi E , Macchia M , Minutolo F , Laprairie RB , Granchi C , Tuccinardi T |
| Ref : Bioorg Chem , 163 :108698 , 2025 |
| Abstract : |
| PubMedSearch : Bononi_2025_Bioorg.Chem_163_108698 |
| PubMedID: 40554889 |
| Gene_locus related to this paper: human-MGLL |
| Title : Methods for Assessing MAGL Enzymatic Activity: An Extensive Review of Past and Emerging Approaches - Bononi_2025_Int.J.Mol.Sci_26_9829 |
| Author(s) : Bononi G , Landucci E , Di Stefano M , Piazza L , Bertini S , Macchia M , Granchi C |
| Ref : Int J Mol Sci , 26 :9829 , 2025 |
| Abstract : |
| PubMedSearch : Bononi_2025_Int.J.Mol.Sci_26_9829 |
| PubMedID: 41097094 |
| Gene_locus related to this paper: human-MGLL |
| Title : Watermelon: setup and validation of an in silico fragment-based approach - Di Stefano_2024_J.Enzyme.Inhib.Med.Chem_39_2356179 |
| Author(s) : Di Stefano M , Galati S , Piazza L , Gado F , Granchi C , Macchia M , Giordano A , Tuccinardi T , Poli G |
| Ref : J Enzyme Inhib Med Chem , 39 :2356179 , 2024 |
| Abstract : |
| PubMedSearch : Di Stefano_2024_J.Enzyme.Inhib.Med.Chem_39_2356179 |
| PubMedID: 38864179 |
| Title : Watermelon: setup and validation of an in silico fragment-based approach - Di Stefano_2024_J.Enzyme.Inhib.Med.Chem_39_2356179 |
| Author(s) : Di Stefano M , Galati S , Piazza L , Gado F , Granchi C , Macchia M , Giordano A , Tuccinardi T , Poli G |
| Ref : J Enzyme Inhib Med Chem , 39 :2356179 , 2024 |
| Abstract : |
| PubMedSearch : Di Stefano_2024_J.Enzyme.Inhib.Med.Chem_39_2356179 |
| PubMedID: 38864179 |
| Title : Watermelon: setup and validation of an in silico fragment-based approach - Di Stefano_2024_J.Enzyme.Inhib.Med.Chem_39_2356179 |
| Author(s) : Di Stefano M , Galati S , Piazza L , Gado F , Granchi C , Macchia M , Giordano A , Tuccinardi T , Poli G |
| Ref : J Enzyme Inhib Med Chem , 39 :2356179 , 2024 |
| Abstract : |
| PubMedSearch : Di Stefano_2024_J.Enzyme.Inhib.Med.Chem_39_2356179 |
| PubMedID: 38864179 |
| Title : Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors - Di Stefano_2023_Eur.J.Med.Chem_263_115916 |
| Author(s) : Di Stefano M , Masoni S , Bononi G , Poli G , Galati S , Gado F , Manzi S , Vagaggini C , Brai A , Caligiuri I , Asif K , Rizzolio F , Macchia M , Chicca A , Sodi A , Di Bussolo V , Minutolo F , Meier P , Gertsch J , Granchi C , Dreassi E , Tuccinardi T |
| Ref : Eur Journal of Medicinal Chemistry , 263 :115916 , 2023 |
| Abstract : |
| PubMedSearch : Di Stefano_2023_Eur.J.Med.Chem_263_115916 |
| PubMedID: 37976705 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors - Di Stefano_2023_Eur.J.Med.Chem_263_115916 |
| Author(s) : Di Stefano M , Masoni S , Bononi G , Poli G , Galati S , Gado F , Manzi S , Vagaggini C , Brai A , Caligiuri I , Asif K , Rizzolio F , Macchia M , Chicca A , Sodi A , Di Bussolo V , Minutolo F , Meier P , Gertsch J , Granchi C , Dreassi E , Tuccinardi T |
| Ref : Eur Journal of Medicinal Chemistry , 263 :115916 , 2023 |
| Abstract : |
| PubMedSearch : Di Stefano_2023_Eur.J.Med.Chem_263_115916 |
| PubMedID: 37976705 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors - Di Stefano_2023_Eur.J.Med.Chem_263_115916 |
| Author(s) : Di Stefano M , Masoni S , Bononi G , Poli G , Galati S , Gado F , Manzi S , Vagaggini C , Brai A , Caligiuri I , Asif K , Rizzolio F , Macchia M , Chicca A , Sodi A , Di Bussolo V , Minutolo F , Meier P , Gertsch J , Granchi C , Dreassi E , Tuccinardi T |
| Ref : Eur Journal of Medicinal Chemistry , 263 :115916 , 2023 |
| Abstract : |
| PubMedSearch : Di Stefano_2023_Eur.J.Med.Chem_263_115916 |
| PubMedID: 37976705 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives - Bononi_2022_J.Med.Chem__ |
| Author(s) : Bononi G , Di Stefano M , Poli G , Ortore G , Meier P , Masetto F , Caligiuri I , Rizzolio F , Macchia M , Chicca A , Avan A , Giovannetti E , Vagaggini C , Brai A , Dreassi E , Valoti M , Minutolo F , Granchi C , Gertsch J , Tuccinardi T |
| Ref : Journal of Medicinal Chemistry , : , 2022 |
| Abstract : |
| PubMedSearch : Bononi_2022_J.Med.Chem__ |
| PubMedID: 35522977 |
| Title : Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives - Bononi_2022_J.Med.Chem__ |
| Author(s) : Bononi G , Di Stefano M , Poli G , Ortore G , Meier P , Masetto F , Caligiuri I , Rizzolio F , Macchia M , Chicca A , Avan A , Giovannetti E , Vagaggini C , Brai A , Dreassi E , Valoti M , Minutolo F , Granchi C , Gertsch J , Tuccinardi T |
| Ref : Journal of Medicinal Chemistry , : , 2022 |
| Abstract : |
| PubMedSearch : Bononi_2022_J.Med.Chem__ |
| PubMedID: 35522977 |
| Title : Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives - Bononi_2022_J.Med.Chem__ |
| Author(s) : Bononi G , Di Stefano M , Poli G , Ortore G , Meier P , Masetto F , Caligiuri I , Rizzolio F , Macchia M , Chicca A , Avan A , Giovannetti E , Vagaggini C , Brai A , Dreassi E , Valoti M , Minutolo F , Granchi C , Gertsch J , Tuccinardi T |
| Ref : Journal of Medicinal Chemistry , : , 2022 |
| Abstract : |
| PubMedSearch : Bononi_2022_J.Med.Chem__ |
| PubMedID: 35522977 |
| Title : Discovery of Monoacylglycerol Lipase (MAGL) Inhibitors Based on a Pharmacophore-Guided Virtual Screening Study - Jha_2020_Molecules_26_ |
| Author(s) : Jha V , Biagi M , Spinelli V , Di Stefano M , Macchia M , Minutolo F , Granchi C , Poli G , Tuccinardi T |
| Ref : Molecules , 26 : , 2020 |
| Abstract : |
| PubMedSearch : Jha_2020_Molecules_26_ |
| PubMedID: 33375358 |
| Title : Discovery of Monoacylglycerol Lipase (MAGL) Inhibitors Based on a Pharmacophore-Guided Virtual Screening Study - Jha_2020_Molecules_26_ |
| Author(s) : Jha V , Biagi M , Spinelli V , Di Stefano M , Macchia M , Minutolo F , Granchi C , Poli G , Tuccinardi T |
| Ref : Molecules , 26 : , 2020 |
| Abstract : |
| PubMedSearch : Jha_2020_Molecules_26_ |
| PubMedID: 33375358 |
| Title : Discovery of Monoacylglycerol Lipase (MAGL) Inhibitors Based on a Pharmacophore-Guided Virtual Screening Study - Jha_2020_Molecules_26_ |
| Author(s) : Jha V , Biagi M , Spinelli V , Di Stefano M , Macchia M , Minutolo F , Granchi C , Poli G , Tuccinardi T |
| Ref : Molecules , 26 : , 2020 |
| Abstract : |
| PubMedSearch : Jha_2020_Molecules_26_ |
| PubMedID: 33375358 |
| Title : Neostigmine-induced postprandial phasic contractility in the proximal stomach and dyspepsia-like symptoms in healthy volunteers - Di Stefano_2006_Am.J.Gastroenterol_101_2797 |
| Author(s) : Di Stefano M , Vos R , Klersy C , Lee KJ , Janssens J , Tack J |
| Ref : Am J Gastroenterol , 101 :2797 , 2006 |
| Abstract : |
| PubMedSearch : Di Stefano_2006_Am.J.Gastroenterol_101_2797 |
| PubMedID: 17227525 |
| Title : Neostigmine-induced postprandial phasic contractility in the proximal stomach and dyspepsia-like symptoms in healthy volunteers - Di Stefano_2006_Am.J.Gastroenterol_101_2797 |
| Author(s) : Di Stefano M , Vos R , Klersy C , Lee KJ , Janssens J , Tack J |
| Ref : Am J Gastroenterol , 101 :2797 , 2006 |
| Abstract : |
| PubMedSearch : Di Stefano_2006_Am.J.Gastroenterol_101_2797 |
| PubMedID: 17227525 |
| Title : Neostigmine-induced postprandial phasic contractility in the proximal stomach and dyspepsia-like symptoms in healthy volunteers - Di Stefano_2006_Am.J.Gastroenterol_101_2797 |
| Author(s) : Di Stefano M , Vos R , Klersy C , Lee KJ , Janssens J , Tack J |
| Ref : Am J Gastroenterol , 101 :2797 , 2006 |
| Abstract : |
| PubMedSearch : Di Stefano_2006_Am.J.Gastroenterol_101_2797 |
| PubMedID: 17227525 |
| Title : Influence of mental motor imagery on the execution of a finger-to-thumb opposition task - Gemignani_2004_Arch.Ital.Biol_142_1 |
| Author(s) : Gemignani A , Di Stefano M , Sebastiani L , Ghelarducci B , Jeannerod M , Guazzelli M , Massarelli R |
| Ref : Archives Italiennes de Biologie , 142 :1 , 2004 |
| Abstract : |
| PubMedSearch : Gemignani_2004_Arch.Ital.Biol_142_1 |
| PubMedID: 15143619 |
| Title : Influence of mental motor imagery on the execution of a finger-to-thumb opposition task - Gemignani_2004_Arch.Ital.Biol_142_1 |
| Author(s) : Gemignani A , Di Stefano M , Sebastiani L , Ghelarducci B , Jeannerod M , Guazzelli M , Massarelli R |
| Ref : Archives Italiennes de Biologie , 142 :1 , 2004 |
| Abstract : |
| PubMedSearch : Gemignani_2004_Arch.Ital.Biol_142_1 |
| PubMedID: 15143619 |
| Title : Influence of mental motor imagery on the execution of a finger-to-thumb opposition task - Gemignani_2004_Arch.Ital.Biol_142_1 |
| Author(s) : Gemignani A , Di Stefano M , Sebastiani L , Ghelarducci B , Jeannerod M , Guazzelli M , Massarelli R |
| Ref : Archives Italiennes de Biologie , 142 :1 , 2004 |
| Abstract : |
| PubMedSearch : Gemignani_2004_Arch.Ital.Biol_142_1 |
| PubMedID: 15143619 |