Ghelardini C

General

Full name : Ghelardini Carla

First name : Carla

Mail : University of Florence, Department of Preclinical and Clinical Pharmacology, Viale Pieraccini 6, Florence, 50139

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Country : Italy

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References (30)

Title : Inhibition of Monoacylglycerol Lipase by NSD1819 as an Effective Strategy for the Endocannabinoid System Modulation against Neuroinflammation-Related Disorders - Micheli_2022_Int.J.Mol.Sci_23_8428
Author(s) : Micheli L , Maramai S , Toti A , Ferrara V , Ciampi C , Di Cesare Mannelli L , Ghelardini C
Ref : Int J Mol Sci , 23 : , 2022
Abstract :
PubMedSearch : Micheli_2022_Int.J.Mol.Sci_23_8428
PubMedID: 35955562

Title : Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors - Aghazadeh Tabrizi_2018_J.Med.Chem_61_1340
Author(s) : Aghazadeh Tabrizi M , Baraldi PG , Baraldi S , Ruggiero E , De Stefano L , Rizzolio F , Di Cesare Mannelli L , Ghelardini C , Chicca A , Lapillo M , Gertsch J , Manera C , Macchia M , Martinelli A , Granchi C , Minutolo F , Tuccinardi T
Ref : Journal of Medicinal Chemistry , 61 :1340 , 2018
Abstract :
PubMedSearch : Aghazadeh Tabrizi_2018_J.Med.Chem_61_1340
PubMedID: 29309142

Title : Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain - Brindisi_2016_J.Med.Chem_59_2612
Author(s) : Brindisi M , Maramai S , Gemma S , Brogi S , Grillo A , Di Cesare Mannelli L , Gabellieri E , Lamponi S , Saponara S , Gorelli B , Tedesco D , Bonfiglio T , Landry C , Jung KM , Armirotti A , Luongo L , Ligresti A , Piscitelli F , Bertucci C , Dehouck MP , Campiani G , Maione S , Ghelardini C , Pittaluga A , Piomelli D , Di Marzo V , Butini S
Ref : Journal of Medicinal Chemistry , 59 :2612 , 2016
Abstract :
PubMedSearch : Brindisi_2016_J.Med.Chem_59_2612
PubMedID: 26888301

Title : Involvement of alpha7 nAChR subtype in rat oxaliplatin-induced neuropathy: Effects of selective activation - Di Cesare_2014_Neuropharmacol_79_37
Author(s) : Di Cesare Mannelli L , Pacini A , Matera C , Zanardelli M , Mello T , De Amici M , Dallanoce C , Ghelardini C
Ref : Neuropharmacology , 79 :37 , 2014
Abstract :
PubMedSearch : Di Cesare_2014_Neuropharmacol_79_37
PubMedID: 24225197

Title : Analgesic and antineuropathic drugs acting through central cholinergic mechanisms - Bartolini_2011_Recent.Pat.CNS.Drug.Discov_6_119
Author(s) : Bartolini A , Di Cesare Mannelli L , Ghelardini C
Ref : Recent Pat CNS Drug Discov , 6 :119 , 2011
Abstract :
PubMedSearch : Bartolini_2011_Recent.Pat.CNS.Drug.Discov_6_119
PubMedID: 21585331

Title : Neuropathy-induced apoptosis: protective effect of physostigmine - Di Cesare Mannelli_2009_J.Neurosci.Res_87_1871
Author(s) : Di Cesare Mannelli L , Bartolini A , Ghelardini C
Ref : Journal of Neuroscience Research , 87 :1871 , 2009
Abstract :
PubMedSearch : Di Cesare Mannelli_2009_J.Neurosci.Res_87_1871
PubMedID: 19170187

Title : Design, synthesis, and preliminary pharmacological evaluation of new quinoline derivatives as nicotinic ligands - Guandalini_2007_J.Med.Chem_50_4993
Author(s) : Guandalini L , Norcini M , Varani K , Pistolozzi M , Gotti C , Bazzicalupi C , Martini E , Dei S , Manetti D , Scapecchi S , Teodori E , Bertucci C , Ghelardini C , Romanelli MN
Ref : Journal of Medicinal Chemistry , 50 :4993 , 2007
Abstract :
PubMedSearch : Guandalini_2007_J.Med.Chem_50_4993
PubMedID: 17850058

Title : Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition enhancers - Romanelli_2006_CNS.Drug.Rev_12_39
Author(s) : Romanelli MN , Galeotti N , Ghelardini C , Manetti D , Martini E , Gualtieri F
Ref : CNS Drug Rev , 12 :39 , 2006
Abstract :
PubMedSearch : Romanelli_2006_CNS.Drug.Rev_12_39
PubMedID: 16834757

Title : Ryanodine receptors are involved in muscarinic antinociception in mice - Galeotti_2005_Behav.Brain.Res_164_165
Author(s) : Galeotti N , Bartolini A , Ghelardini C
Ref : Behavioural Brain Research , 164 :165 , 2005
Abstract :
PubMedSearch : Galeotti_2005_Behav.Brain.Res_164_165
PubMedID: 16051378

Title : The phospholipase C-IP3 pathway is involved in muscarinic antinociception - Galeotti_2003_Neuropsychopharmacology_28_888
Author(s) : Galeotti N , Bartolini A , Ghelardini C
Ref : Neuropsychopharmacology , 28 :888 , 2003
Abstract :
PubMedSearch : Galeotti_2003_Neuropsychopharmacology_28_888
PubMedID: 12736633

Title : Central cholinergic challenging of migraine by testing second-generation anticholinesterase drugs - Nicolodi_2002_Headache_42_596
Author(s) : Nicolodi M , Galeotti N , Ghelardini C , Bartolini A , Sicuteri F
Ref : Headache , 42 :596 , 2002
Abstract :
PubMedSearch : Nicolodi_2002_Headache_42_596
PubMedID: 12482211

Title : Loss of muscarinic antinociception by antisense inhibition of M(1) receptors - Ghelardini_2000_Br.J.Pharmacol_129_1633
Author(s) : Ghelardini C , Galeotti N , Bartolini A
Ref : British Journal of Pharmacology , 129 :1633 , 2000
Abstract :
PubMedSearch : Ghelardini_2000_Br.J.Pharmacol_129_1633
PubMedID: 10780968

Title : Pro-cognitive activity induced in the rat by low doses of R-(+)-hyoscyamine - Ghelardini_2000_Fitoterapia_71 Suppl 1_S124
Author(s) : Ghelardini C , Galeotti N , Bartolini A
Ref : Fitoterapia , 71 Suppl 1 :S124 , 2000
Abstract :
PubMedSearch : Ghelardini_2000_Fitoterapia_71 Suppl 1_S124
PubMedID: 10930723

Title : Role of 5-HT1A receptors in a mouse passive avoidance paradigm - Galeotti_2000_Jpn.J.Pharmacol_84_418
Author(s) : Galeotti N , Ghelardini C , Bartolini A
Ref : Japanese Journal of Pharmacology , 84 :418 , 2000
Abstract :
PubMedSearch : Galeotti_2000_Jpn.J.Pharmacol_84_418
PubMedID: 11202614

Title : Antinociceptive effect of R-(+)-hyoscyamine on the conjunctival reflex test in rabbits - Ghelardini_1999_Jpn.J.Pharmacol_81_34
Author(s) : Ghelardini C , Galeotti N , Fantetti L , Gualtieri F , Scapecchi S , Bartolini A
Ref : Japanese Journal of Pharmacology , 81 :34 , 1999
Abstract :
PubMedSearch : Ghelardini_1999_Jpn.J.Pharmacol_81_34
PubMedID: 10580368

Title : Memory facilitation and stimulation of endogenous nerve growth factor synthesis by the acetylcholine releaser PG-9 - Ghelardini_1998_Jpn.J.Pharmacol_78_245
Author(s) : Ghelardini C , Galeotti N , Bartolini A , Furukawa S , Nitta A , Manetti D , Gualtieri F
Ref : Japanese Journal of Pharmacology , 78 :245 , 1998
Abstract :
PubMedSearch : Ghelardini_1998_Jpn.J.Pharmacol_78_245
PubMedID: 9869257

Title : Antinociceptive and antiamnesic properties of the presynaptic cholinergic amplifier PG-9 - Ghelardini_1998_J.Pharmacol.Exp.Ther_284_806
Author(s) : Ghelardini C , Galeotti N , Gualtieri F , Marchese V , Bellucci C , Bartolini A
Ref : Journal of Pharmacology & Experimental Therapeutics , 284 :806 , 1998
Abstract :
PubMedSearch : Ghelardini_1998_J.Pharmacol.Exp.Ther_284_806
PubMedID: 9495837

Title : Stereoselective increase in cholinergic transmission by R-(+)-hyoscyamine - Ghelardini_1997_Neuropharmacol_36_281
Author(s) : Ghelardini C , Gualtieri F , Romanelli MN , Angeli P , Pepeu G , Giovannini MG , Casamenti F , Malmberg-Aiello P , Giotti A , Bartolini A
Ref : Neuropharmacology , 36 :281 , 1997
Abstract :
PubMedSearch : Ghelardini_1997_Neuropharmacol_36_281
PubMedID: 9175606

Title : S-(-)-ET 126: a potent and selective M1 antagonist in vitro and in vivo - Ghelardini_1996_Life.Sci_58_991
Author(s) : Ghelardini C , Bartolini A , Galeotti N , Teodori E , Gualtieri F
Ref : Life Sciences , 58 :991 , 1996
Abstract :
PubMedSearch : Ghelardini_1996_Life.Sci_58_991
PubMedID: 8786711

Title : Chiral synthesis and pharmacological evaluation of the enantiomers of SM32, a new analgesic and cognition-enhancing agent - Romanelli_1996_Chirality_8_579
Author(s) : Romanelli MN , Bartolini A , Bertucci C , Dei S , Ghelardini C , Giovannini MG , Gualtieri F , Pepeu G , Scapecchi S , Teodori E
Ref : Chirality , 8 :579 , 1996
Abstract :
PubMedSearch : Romanelli_1996_Chirality_8_579
PubMedID: 9025257

Title : Synthesis and enantioselectivity of the enantiomers of PG9 and SM21, new potent analgesic and cognition-enhancing drugs - Romanelli_1996_Chirality_8_225
Author(s) : Romanelli MN , Bartolini A , Bertucci C , Dei S , Ghelardini C , Giovannini MG , Gualtieri F , Pepeu G , Scapecchi S , Teodori E
Ref : Chirality , 8 :225 , 1996
Abstract :
PubMedSearch : Romanelli_1996_Chirality_8_225
PubMedID: 8777145

Title : Poster: S-()-ET 126: A potent and selective M1 antagonist -
Author(s) : Galeotti N , Ghelardini C , Baldini M , Gherardini L , Gualtieri F , Dei S , Bartolini A
Ref : Life Sciences , 56(11-12) :1008 , 1995
PubMedID:

Title : Poster: alpha-Tropanyl esters that increase central ACh release: Enantioselectivity studies support a double mechanism of action -
Author(s) : Gualtieri F , Bartolini A , Bertucci C , Dei S , Ghelardini C , Giovannini MG , Giotti A , Pepeu G , Romanelli MN , Scapecchi S , Teodori E
Ref : Life Sciences , 56(11-12) :1015 , 1995
PubMedID:

Title : Presynaptic cholinergic modulators as potent cognition enhancers and analgesic drugs. 2. 2-Phenoxy-, 2-(phenylthio)-, and 2-(phenylamino)alkanoic acid esters - Gualtieri_1994_J.Med.Chem_37_1712
Author(s) : Gualtieri F , Bottalico C , Calandrella A , Dei S , Giovannoni MP , Mealli S , Romanelli MN , Scapecchi S , Teodori E , Galeotti N , Ghelardini C , Giotti A , Bartolini A
Ref : Journal of Medicinal Chemistry , 37 :1712 , 1994
Abstract :
PubMedSearch : Gualtieri_1994_J.Med.Chem_37_1712
PubMedID: 8201606

Title : Presynaptic cholinergic modulators as potent cognition enhancers and analgesic drugs. 1. Tropic and 2-phenylpropionic acid esters - Gualtieri_1994_J.Med.Chem_37_1704
Author(s) : Gualtieri F , Conti G , Dei S , Giovannoni MP , Nannucci F , Romanelli MN , Scapecchi S , Teodori E , Fanfani L , Ghelardini C , Giotti A , Bartolini A
Ref : Journal of Medicinal Chemistry , 37 :1704 , 1994
Abstract :
PubMedSearch : Gualtieri_1994_J.Med.Chem_37_1704
PubMedID: 8201605

Title : Poster: R-(+)-hyoscyamine: The first selective antagonist for guinea-pig uterus muscarinic receptor subtype -
Author(s) : Ghelardini C , Gualtieri F , Baldini M , Dei S , Romanelli MN , Giotti A , Bartolini A
Ref : Life Sciences , 52(5-6) :569 , 1993
PubMedID:

Title : Poster: Affinity profile of S(-)-hyoscyamine for muscarinic receptor subtypes -
Author(s) : Scapecchi S , Bellucci C , Ghelardini C , Gheri A , Giotti A , Gualtieri F , Bartolini A
Ref : Life Sciences , 52(5-6) :568 , 1993
PubMedID:

Title : Poster: i.c.v. AFDX- 116 induces analgesia only when administrred at very low doses -
Author(s) : Bartolini A , Ghelardini C , Gualtleri F , Malcangio M , Malmberg-Aiello P , Romanelli N , Giotti A
Ref : Trends in Pharmacological Sciences , Suppl :99 , 1989
PubMedID:

Title : Poster: Muscarinic M1 contrary to M2 antagonists do not induce analgesia -
Author(s) : Ghelardini C , Giotti A , Gualtieri F , Malcangio M , Malmberg-Aiello P , Scapecchi S , Bartolini A
Ref : Trends in Pharmacological Sciences , Suppl :99 , 1989
PubMedID:

Title : Poster: Analgesia induced by the M2 antagonist methoctramine administered i.c.v. -
Author(s) : Gualtieri F , Ghelardini C , Giotti A , Malcangio M , Malmberg-Aiello P , Bartolini A
Ref : Trends in Pharmacological Sciences , Suppl :99 , 1989
PubMedID: