| Title : Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization - Butini_2024_J.Med.Chem__ |
| Author(s) : Butini S , Grether U , Jung KM , Ligresti A , Allara M , Postmus AGJ , Maramai S , Brogi S , Papa A , Carullo G , Sykes D , Veprintsev D , Federico S , Grillo A , Di Guglielmo B , Ramunno A , Stevens AF , Heer D , Lamponi S , Gemma S , Benz J , Di Marzo V , van der Stelt M , Piomelli D , Campiani G |
| Ref : Journal of Medicinal Chemistry , : , 2024 |
| Abstract : |
| PubMedSearch : Butini_2024_J.Med.Chem__ |
| PubMedID: 38241614 |
| Gene_locus related to this paper: human-MGLL |
| Title : MicroRNA-Based Multitarget Approach for Alzheimer's Disease: Discovery of the First-In-Class Dual Inhibitor of Acetylcholinesterase and MicroRNA-15b Biogenesis - Gabr_2020_J.Med.Chem_63_9695 |
| Author(s) : Gabr MT , Brogi S |
| Ref : Journal of Medicinal Chemistry , 63 :9695 , 2020 |
| Abstract : |
| PubMedSearch : Gabr_2020_J.Med.Chem_63_9695 |
| PubMedID: 32787143 |
| Title : Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease - Ismaili_2017_Prog.Neurobiol_151_4 |
| Author(s) : Ismaili L , Refouvelet B , Benchekroun M , Brogi S , Brindisi M , Gemma S , Campiani G , Filipic S , Agbaba D , Esteban G , Unzeta M , Nikolic K , Butini S , Marco-Contelles J |
| Ref : Prog Neurobiol , 151 :4 , 2017 |
| Abstract : |
| PubMedSearch : Ismaili_2017_Prog.Neurobiol_151_4 |
| PubMedID: 26797191 |
| Title : Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain - Brindisi_2016_J.Med.Chem_59_2612 |
| Author(s) : Brindisi M , Maramai S , Gemma S , Brogi S , Grillo A , Di Cesare Mannelli L , Gabellieri E , Lamponi S , Saponara S , Gorelli B , Tedesco D , Bonfiglio T , Landry C , Jung KM , Armirotti A , Luongo L , Ligresti A , Piscitelli F , Bertucci C , Dehouck MP , Campiani G , Maione S , Ghelardini C , Pittaluga A , Piomelli D , Di Marzo V , Butini S |
| Ref : Journal of Medicinal Chemistry , 59 :2612 , 2016 |
| Abstract : |
| PubMedSearch : Brindisi_2016_J.Med.Chem_59_2612 |
| PubMedID: 26888301 |
| Title : Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation - Wu_2016_Eur.J.Med.Chem_121_864 |
| Author(s) : Wu MY , Esteban G , Brogi S , Shionoya M , Wang L , Campiani G , Unzeta M , Inokuchi T , Butini S , Marco-Contelles J |
| Ref : Eur Journal of Medicinal Chemistry , 121 :864 , 2016 |
| Abstract : |
| PubMedSearch : Wu_2016_Eur.J.Med.Chem_121_864 |
| PubMedID: 26471320 |
| Title : Disease-Modifying Anti-Alzheimer's Drugs: Inhibitors of Human Cholinesterases Interfering with beta-Amyloid Aggregation - Brogi_2014_CNS.Neurosci.Ther_20_624 |
| Author(s) : Brogi S , Butini S , Maramai S , Colombo R , Verga L , Lanni C , De Lorenzi E , Lamponi S , Andreassi M , Bartolini M , Andrisano V , Novellino E , Campiani G , Brindisi M , Gemma S |
| Ref : CNS Neurosci Ther , 20 :624 , 2014 |
| Abstract : |
| PubMedSearch : Brogi_2014_CNS.Neurosci.Ther_20_624 |
| PubMedID: 24935788 |
| Title : Multifunctional cholinesterase and amyloid Beta fibrillization modulators. Synthesis and biological investigation - Butini_2013_ACS.Med.Chem.Lett_4_1178 |
| Author(s) : Butini S , Brindisi M , Brogi S , Maramai S , Guarino E , Panico A , Saxena A , Chauhan V , Colombo R , Verga L , De Lorenzi E , Bartolini M , Andrisano V , Novellino E , Campiani G , Gemma S |
| Ref : ACS Med Chem Lett , 4 :1178 , 2013 |
| Abstract : |
| PubMedSearch : Butini_2013_ACS.Med.Chem.Lett_4_1178 |
| PubMedID: 24900626 |