| Title : Screening and Biological Evaluation of Soluble Epoxide Hydrolase Inhibitors: Assessing the Role of Hydrophobicity in the Pharmacophore-Guided Search of Novel Hits - Vazquez_2023_J.Chem.Inf.Model__ |
| Author(s) : Vazquez J , Ginex T , Herrero A , Morisseau C , Hammock BD , Luque FJ |
| Ref : J Chem Inf Model , : , 2023 |
| Abstract : |
| PubMedSearch : Vazquez_2023_J.Chem.Inf.Model__ |
| PubMedID: 37141492 |
| Title : From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects - Pont_2021_Eur.J.Med.Chem_225_113779 |
| Author(s) : Pont C , Ginex T , Grinan-Ferre C , Scheiner M , Mattellone A , Martinez N , Arce EM , Soriano-Fernandez Y , Naldi M , De Simone A , Barenys M , Gomez-Catalan J , Perez B , Sabate R , Andrisano V , Loza MI , Brea J , Bartolini M , Bolognesi ML , Decker M , Pallas M , Luque FJ , Munoz-Torrero D |
| Ref : Eur Journal of Medicinal Chemistry , 225 :113779 , 2021 |
| Abstract : |
| PubMedSearch : Pont_2021_Eur.J.Med.Chem_225_113779 |
| PubMedID: 34418785 |
| Title : Azobioisosteres of Curcumin with Pronounced Activity against Amyloid Aggregation, Intracellular Oxidative Stress, and Neuroinflammation - Hofmann_2021_Chemistry_27_6015 |
| Author(s) : Hofmann J , Ginex T , Espargaro A , Scheiner M , Gunesch S , Arago M , Stigloher C , Sabate R , Luque FJ , Decker M |
| Ref : Chemistry , 27 :6015 , 2021 |
| Abstract : |
| PubMedSearch : Hofmann_2021_Chemistry_27_6015 |
| PubMedID: 33666306 |
| Title : Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6 - Perez-Areales_2020_J.Med.Chem_63_9360 |
| Author(s) : Perez-Areales FJ , Garrido M , Aso E , Bartolini M , De Simone A , Espargaro A , Ginex T , Sabate R , Perez B , Andrisano V , Puigoriol-Illamola D , Pallas M , Luque FJ , Loza MI , Brea J , Ferrer I , Ciruela F , Messeguer A , Munoz-Torrero D |
| Ref : Journal of Medicinal Chemistry , 63 :9360 , 2020 |
| Abstract : |
| PubMedSearch : Perez-Areales_2020_J.Med.Chem_63_9360 |
| PubMedID: 32706255 |
| Title : Design, synthesis and docking study of novel coumarin ligands as potential selective acetylcholinesterase inhibitors - Sonmez_2017_J.Enzyme.Inhib.Med.Chem_32_285 |
| Author(s) : Sonmez F , Zengin Kurt B , Gazioglu I , Basile L , Dag A , Cappello V , Ginex T , Kucukislamoglu M , Guccione S |
| Ref : J Enzyme Inhib Med Chem , 32 :285 , 2017 |
| Abstract : |
| PubMedSearch : Sonmez_2017_J.Enzyme.Inhib.Med.Chem_32_285 |
| PubMedID: 28097911 |
| Title : Potential of aryl-urea-benzofuranylthiazoles hybrids as multitasking agents in Alzheimer's disease - Kurt_2015_Eur.J.Med.Chem_102_80 |
| Author(s) : Kurt BZ , Gazioglu I , Basile L , Sonmez F , Ginex T , Kucukislamoglu M , Guccione S |
| Ref : Eur Journal of Medicinal Chemistry , 102 :80 , 2015 |
| Abstract : |
| PubMedSearch : Kurt_2015_Eur.J.Med.Chem_102_80 |
| PubMedID: 26244990 |