| Title : MS Binding Assays with UNC0642 as reporter ligand for the MB327 binding site of the nicotinic acetylcholine receptor - Nitsche_2024_Toxicol.Lett_392_94 |
| Author(s) : Nitsche V , Hofner G , Kaiser J , Gertzen CGW , Seeger T , Niessen KV , Steinritz D , Worek F , Gohlke H , Paintner FF , Wanner KT |
| Ref : Toxicol Lett , 392 :94 , 2024 |
| Abstract : |
| PubMedSearch : Nitsche_2024_Toxicol.Lett_392_94 |
| PubMedID: 38216073 |
| Title : Synthesis and Biological Evaluation of Novel MB327 Analogs as Resensitizers for Desensitized Nicotinic Acetylcholine Receptors after Intoxication with Nerve Agents - Bernauer_2024_Toxicol.Lett__ |
| Author(s) : Bernauer T , Nitsche V , Kaiser J , Gertzen CGW , Hofner G , Niessen KV , Seeger T , Steinritz D , Worek F , Gohlke H , Wanner KT , Paintner FF |
| Ref : Toxicol Lett , : , 2024 |
| Abstract : |
| PubMedSearch : Bernauer_2024_Toxicol.Lett__ |
| PubMedID: 38759939 |
| Title : An archaeal lid-containing feruloyl esterase degrades polyethylene terephthalate - Perez-Garcia_2023_Commun.Chem_6_193 |
| Author(s) : Perez-Garcia P , Chow J , Costanzi E , Gurschke M , Dittrich J , Dierkes RF , Molitor R , Applegate V , Feuerriegel G , Tete P , Danso D , Thies S , Schumacher J , Pfleger C , Jaeger KE , Gohlke H , Smits SHJ , Schmitz RA , Streit WR |
| Ref : Commun Chem , 6 :193 , 2023 |
| Abstract : |
| PubMedSearch : Perez-Garcia_2023_Commun.Chem_6_193 |
| PubMedID: 37697032 |
| Gene_locus related to this paper: 9arch-PETcan211 , 9cren-PETcan204 , 9arch-PET46 |
| Title : A novel binding site in the nicotinic acetylcholine receptor for MB327 can explain its allosteric modulation relevant for organophosphorus-poisoning treatment - Kaiser_2023_Toxicol.Lett_373_160 |
| Author(s) : Kaiser J , Gertzen CGW , Bernauer T , Hofner G , Niessen KV , Seeger T , Paintner FF , Wanner KT , Worek F , Thiermann H , Gohlke H |
| Ref : Toxicol Lett , 373 :160 , 2023 |
| Abstract : |
| PubMedSearch : Kaiser_2023_Toxicol.Lett_373_160 |
| PubMedID: 36503818 |
| Title : The metagenome-derived esterase PET40 is highly promiscuous and hydrolyses polyethylene terephthalate (PET) - Zhang_2023_Febs.j__ |
| Author(s) : Zhang H , Dierkes RF , Perez-Garcia P , Costanzi E , Dittrich J , Cea PA , Gurschke M , Applegate V , Partus K , Schmeisser C , Pfleger C , Gohlke H , Smits SHJ , Chow J , Streit WR |
| Ref : Febs J , : , 2023 |
| Abstract : |
| PubMedSearch : Zhang_2023_Febs.j__ |
| PubMedID: 37549040 |
| Gene_locus related to this paper: 9pseu-PET40 |
| Title : Resolution of Maximum Entropy Method-Derived Posterior Conformational Ensembles of a Flexible System Probed by FRET and Molecular Dynamics Simulations - Dittrich_2023_J.Chem.Theory.Comput__ |
| Author(s) : Dittrich J , Popara M , Kubiak J , Dimura M , Schepers B , Verma N , Schmitz B , Dollinger P , Kovacic F , Jaeger KE , Seidel CAM , Peulen TO , Gohlke H |
| Ref : J Chem Theory Comput , : , 2023 |
| Abstract : |
| PubMedSearch : Dittrich_2023_J.Chem.Theory.Comput__ |
| PubMedID: 37023001 |
| Title : A phospholipase B from Pseudomonas aeruginosa with activity towards endogenous phospholipids affects biofilm assembly - Weiler_2022_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1867_159101 |
| Author(s) : Weiler AJ , Spitz O , Gudzuhn M , Schott-Verdugo SN , Kamel M , Thiele B , Streit WR , Kedrov A , Schmitt L , Gohlk H , Kovacic F , Gohlke H |
| Ref : Biochimica & Biophysica Acta Molecular & Cellular Biology Lipids , 1867 :159101 , 2022 |
| Abstract : |
| PubMedSearch : Weiler_2022_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1867_159101 |
| PubMedID: 35063652 |
| Gene_locus related to this paper: pseae-PA2927 |
| Title : Structural, mechanistic and physiological insights into phospholipase A-mediated membrane phospholipid degradation in Pseudomonas aeruginosa - Bleffert_2022_Elife_11_e72824 |
| Author(s) : Bleffert F , Granzin J , Caliskan M , Schott-Verdugo SN , Siebers M , Thiele B , Rahme LG , Felgner S , Dormann P , Gohlke H , Batra-Safferling R , Erich-Jager K , Kovacic F |
| Ref : Elife , 11 : , 2022 |
| Abstract : |
| PubMedSearch : Bleffert_2022_Elife_11_e72824 |
| PubMedID: 35536643 |
| Gene_locus related to this paper: pseae-PA2949 |
| Title : Critical assessment of structure-based approaches to improve protein resistance in aqueous ionic liquids by enzyme-wide saturation mutagenesis - El Harrar_2022_Comput.Struct.Biotechnol.J_20_399 |
| Author(s) : El Harrar T , Davari MD , Jaeger KE , Schwaneberg U , Gohlke H |
| Ref : Comput Struct Biotechnol J , 20 :399 , 2022 |
| Abstract : |
| PubMedSearch : El Harrar_2022_Comput.Struct.Biotechnol.J_20_399 |
| PubMedID: 35070165 |
| Title : Evidence for a bacterial Lands cycle phospholipase A: Structural and mechanistic insights into membrane phospholipid remodeling - Bleffert_2021_Biorxiv__ |
| Author(s) : Bleffert F , Granzin J , Caliskan M , Schott-Verdugo SN , Siebers M , Thiele B , Rahme L , Felgner S , Dormann P , Gohlke H , Batra-Safferling R , Jaeger KE , Kovacic F |
| Ref : Biorxiv , : , 2021 |
| Abstract : |
| PubMedSearch : Bleffert_2021_Biorxiv__ |
| PubMedID: |
| Gene_locus related to this paper: pseae-PA2949 |
| Title : Substrate access mechanism in a novel membrane-bound 1 phospholipase A of Pseudomonas aeruginosa concordant with specificity and regioselectivity - Ahmad_2021_Biorxiv__ |
| Author(s) : Ahmad S , Strunk CH , Schott-Verdugo SN , Jaeger KE , Kovacic F , Gohlke H |
| Ref : Biorxiv , : , 2021 |
| Abstract : |
| PubMedSearch : Ahmad_2021_Biorxiv__ |
| PubMedID: |
| Gene_locus related to this paper: pseae-PA2949 |
| Title : Discovery of new acetylcholinesterase inhibitors for Alzheimer's disease: virtual screening and in vitro characterisation - David_2021_J.Enzyme.Inhib.Med.Chem_36_491 |
| Author(s) : David B , Schneider P , Schafer P , Pietruszka J , Gohlke H |
| Ref : J Enzyme Inhib Med Chem , 36 :491 , 2021 |
| Abstract : |
| PubMedSearch : David_2021_J.Enzyme.Inhib.Med.Chem_36_491 |
| PubMedID: 33478277 |
| Title : Promiscuous Esterases Counterintuitively Are Less Flexible than Specific Ones - Nutschel_2021_J.Chem.Inf.Model__ |
| Author(s) : Nutschel C , Coscolin C , David B , Mulnaes D , Ferrer M , Jaeger KE , Gohlke H |
| Ref : J Chem Inf Model , : , 2021 |
| Abstract : |
| PubMedSearch : Nutschel_2021_J.Chem.Inf.Model__ |
| PubMedID: 33949194 |
| Title : A Novel Polyester Hydrolase From the Marine Bacterium Pseudomonas aestusnigri - Structural and Functional Insights - Bollinger_2020_Front.Microbiol_11_114 |
| Author(s) : Bollinger A , Thies S , Knieps-Grunhagen E , Gertzen C , Kobus S , Hoppner A , Ferrer M , Gohlke H , Smits SHJ , Jaeger KE |
| Ref : Front Microbiol , 11 :114 , 2020 |
| Abstract : |
| PubMedSearch : Bollinger_2020_Front.Microbiol_11_114 |
| PubMedID: 32117139 |
| Gene_locus related to this paper: 9psed-peh |
| Title : The Membrane-Integrated Steric Chaperone Lif Facilitates Active Site Opening of Pseudomonas aeruginosa Lipase A - Verma_2020_J.Comput.Chem_41_500 |
| Author(s) : Verma N , Dollinger P , Kovacic F , Jaeger KE , Gohlke H |
| Ref : J Comput Chem , 41 :500 , 2020 |
| Abstract : |
| PubMedSearch : Verma_2020_J.Comput.Chem_41_500 |
| PubMedID: 31618459 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation - Viegas_2020_Sci.Rep_10_3578 |
| Author(s) : Viegas A , Dollinger P , Verma N , Kubiak J , Viennet T , Seidel CAM , Gohlke H , Etzkorn M , Kovacic F , Jaeger KE |
| Ref : Sci Rep , 10 :3578 , 2020 |
| Abstract : |
| PubMedSearch : Viegas_2020_Sci.Rep_10_3578 |
| PubMedID: 32107397 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Pseudomonas aeruginosa esterase PA2949, a bacterial homolog of the human membrane esterase ABHD6: expression, purification and crystallization - Bleffert_2019_Acta.Crystallogr.F.Struct.Biol.Commun_75_270 |
| Author(s) : Bleffert F , Granzin J , Gohlke H , Batra-Safferling R , Jaeger KE , Kovacic F |
| Ref : Acta Crystallographica F Struct Biol Commun , 75 :270 , 2019 |
| Abstract : |
| PubMedSearch : Bleffert_2019_Acta.Crystallogr.F.Struct.Biol.Commun_75_270 |
| PubMedID: 30950828 |
| Gene_locus related to this paper: pseae-PA2949 |
| Title : Structural Rigidity and Protein Thermostability in Variants of Lipase A from Bacillus subtilis - Rathi_2015_PLoS.One_10_e0130289 |
| Author(s) : Rathi PC , Jaeger KE , Gohlke H |
| Ref : PLoS ONE , 10 :e0130289 , 2015 |
| Abstract : |
| PubMedSearch : Rathi_2015_PLoS.One_10_e0130289 |
| PubMedID: 26147762 |
| Gene_locus related to this paper: bacsu-lip |