Han YF

General

Full name : Han Yi-Fan

First name : Yi-Fan

Mail : The Hong Kong Polytechnic University, Department of Applied Biology and Chemical Technology, Room Y842, 8\/F, Block Y, The Hong Kong PolyU, Hunghom, KLN, Hong Kong

Zip Code :

City :

Country : China

Email : yifan.han@polyu.edu.hk

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References (28)

Title : Tacrine(10)-Hupyridone Prevents Post-operative Cognitive Dysfunction via the Activation of BDNF Pathway and the Inhibition of AChE in Aged Mice - Chen_2018_Front.Cell.Neurosci_12_396
Author(s) : Chen H , Wu X , Gu X , Zhou Y , Ye L , Zhang K , Pan H , Wang J , Wei H , Zhu B , Naman CB , Mak SH , Carlier PR , Cui W , Han YF
Ref : Front Cell Neurosci , 12 :396 , 2018
PubMedID: 30483056

Title : Sunitinib, a Clinically Used Anticancer Drug, Is a Potent AChE Inhibitor and Attenuates Cognitive Impairments in Mice - Huang_2016_ACS.Chem.Neurosci_7_1047
Author(s) : Huang L , Lin J , Xiang S , Zhao K , Yu J , Zheng J , Xu D , Mak SH , Hu S , Nirasha S , Wang C , Chen X , Zhang J , Xu S , Wei X , Zhang Z , Zhou D , Zhou W , Cui W , Han YF , Hu Z , Wang Q
Ref : ACS Chem Neurosci , 7 :1047 , 2016
PubMedID: 27046396

Title : Protection against beta-amyloid-induced synaptic and memory impairments via altering beta-amyloid assembly by bis(heptyl)-cognitin - Chang_2015_Sci.Rep_5_10256
Author(s) : Chang L , Cui W , Yang Y , Xu S , Zhou WH , Fu HJ , Hu SQ , Mak SH , Hu JW , Wang Q , Pui-Yan Ma V , Chung-Lit Choi T , Dik-Lung Ma E , Tao L , Pang YP , Rowan MJ , Anwyl R , Han YF
Ref : Sci Rep , 5 :10256 , 2015
PubMedID: 26194093

Title : Dimeric bis (heptyl)-Cognitin Blocks Alzheimer's beta-Amyloid Neurotoxicity Via the Inhibition of Abeta Fibrils Formation and Disaggregation of Preformed Fibrils - Hu_2015_CNS.Neurosci.Ther_21_953
Author(s) : Hu SQ , Wang R , Cui W , Mak SH , Li G , Hu YJ , Lee MY , Pang YP , Han YF
Ref : CNS Neurosci Ther , 21 :953 , 2015
PubMedID: 26507365

Title : Substantial Neuroprotection Against K(+) Deprivation-Induced Apoptosis in Primary Cerebellar Granule Neurons by Novel Dimer Bis(propyl)-Cognitin Via the Activation of VEGFR-2 Signaling Pathway - Hu_2013_CNS.Neurosci.Ther_19_764
Author(s) : Hu SQ , Cui W , Xu DP , Mak SH , Tang J , Choi CL , Pang YP , Han YF
Ref : CNS Neurosci Ther , 19 :764 , 2013
PubMedID: 23826635

Title : Reversal of scopolamine-induced spatial and recognition memory deficits in mice by novel multifunctional dimers bis-cognitins - Han_2012_Brain.Res_1470_59
Author(s) : Han RW , Zhang RS , Chang M , Peng YL , Wang P , Hu SQ , Choi CL , Yin M , Wang R , Han YF
Ref : Brain Research , 1470 :59 , 2012
PubMedID: 22750583

Title : Bis(12)-hupyridone, a novel multifunctional dimer, promotes neuronal differentiation more potently than its monomeric natural analog huperzine A possibly through alpha7 nAChR - Cui_2011_Brain.Res_1401_10
Author(s) : Cui W , Cui GZ , Li W , Zhang Z , Hu S , Mak SH , Zhang H , Carlier PR , Choi CL , Wong YT , Lee SM , Han YF
Ref : Brain Research , 1401 :10 , 2011
PubMedID: 21665194

Title : Preventing H(2)O(2)-induced apoptosis in cerebellar granule neurons by regulating the VEGFR-2\/Akt signaling pathway using a novel dimeric antiacetylcholinesterase bis(12)-hupyridone - Cui_2011_Brain.Res_1394_14
Author(s) : Cui W , Li W , Zhao Y , Mak SH , Gao Y , Luo J , Zhang H , Liu Y , Carlier PR , Rong J , Han YF
Ref : Brain Research , 1394 :14 , 2011
PubMedID: 21315693

Title : Tacrine treatment at high dose suppresses the recognition memory in juvenile and adult mice with attention to hepatotoxicity - Pan_2011_Basic.Clin.Pharmacol.Toxicol_108_421
Author(s) : Pan SY , Guo BF , Zhang Y , Yu Q , Yu ZL , Dong H , Ye Y , Han YF , Ko KM
Ref : Basic Clin Pharmacol Toxicol , 108 :421 , 2011
PubMedID: 21232021

Title : Tacrine(2)-ferulic acid, a novel multifunctional dimer, attenuates 6-hydroxydopamine-induced apoptosis in PC12 cells by activating Akt pathway - Zhang_2011_Neurochem.Int_59_981
Author(s) : Zhang H , Mak SH , Cui W , Li W , Han R , Hu S , Ye M , Pi R , Han YF
Ref : Neurochem Int , 59 :981 , 2011
PubMedID: 21939707

Title : Mechanism of bis(7)-tacrine inhibition of GABA-activated current in cultured rat hippocampal neurons - Zhou_2009_Neuropharmacol_57_33
Author(s) : Zhou L , Liu YW , Peoples RW , Yang M , Tian X , Ai YX , Pang YP , Li ZW , Han YF , Li CY
Ref : Neuropharmacology , 57 :33 , 2009
PubMedID: 19393253

Title : Inhibition of NMDA-gated ion channels by bis(7)-tacrine: whole-cell and single-channel studies - Liu_2008_Neuropharmacol_54_1086
Author(s) : Liu YW , Luo JL , Ren H , Peoples RW , Ai YX , Liu LJ , Pang YP , Li ZW , Han YF , Li CY
Ref : Neuropharmacology , 54 :1086 , 2008
PubMedID: 18407299

Title : The physicochemical properties and the in vivo AChE inhibition of two potential anti-Alzheimer agents, bis(12)-hupyridone and bis(7)-tacrine - Yu_2008_J.Pharm.Biomed.Anal_46_75
Author(s) : Yu H , Li WM , Kan KK , Ho JM , Carlier PR , Pang YP , Gu ZM , Zhong Z , Chan K , Wang YT , Han YF
Ref : J Pharm Biomed Anal , 46 :75 , 2008
PubMedID: 17931815

Title : Selective and sensitive determination of bis(7)-tacrine, a high erythrocyte binding acetylcholinesterase inhibitor, in rat plasma by high-performance liquid chromatography-tandem mass spectrometry - Zhang_2008_Biomed.Chromatogr_22_414
Author(s) : Zhang L , Yu H , Li WM , Cheung MC , Pang YP , Lin G , Wang YT , Zuo Z , Han YF
Ref : Biomedical Chromatography , 22 :414 , 2008
PubMedID: 18059054

Title : East meets West in the search for Alzheimer's therapeutics - novel dimeric inhibitors from tacrine and huperzine A - Li_2007_Curr.Alzheimer.Res_4_386
Author(s) : Li WM , Kan KK , Carlier PR , Pang YP , Han YF
Ref : Curr Alzheimer Res , 4 :386 , 2007
PubMedID: 17908041

Title : Huperzine A, a promising anti-Alzheimer?s agent, reduces staurosporine-induced apoptosis in NG108-15 cells. -
Author(s) : Xiao XQ , Wu DC , Gao Y , Fu Y , Lee NT , Ho WL , Tsim KWK , Han YF
Ref : Cholinergic Mechanisms, CRC Press :733 , 2004
PubMedID:

Title : Acetylcholinesterase Complexed with Bivalent Ligands Related to Huperzine A: Experimental Evidence for Species-Dependent Protein-Ligand Complementarity - Wong_2003_J.Am.Chem.Soc_125_363
Author(s) : Wong DM , Greenblatt HM , Dvir H , Carlier PR , Han YF , Pang YP , Silman I , Sussman JL
Ref : J Am Chem Soc , 125 :363 , 2003
PubMedID: 12517147
Gene_locus related to this paper: torca-ACHE

Title : Dimerization of an Inactive Fragment of Huperzine A Produces a Drug with Twice the Potency of the Natural Product -
Author(s) : Carlier PR , Du DM , Han YF , Liu J , Perola E , Williams ID , Pang YP
Ref : Angew Chem Int Ed Engl , 39 :1775 , 2000
PubMedID: 10934357

Title : Learning deficits induced by 4 belladonna alkaloids are preferentially attenuated by tacrine - Pan_2000_Acta.Pharmacol.Sin_21_124
Author(s) : Pan SY , Han YF
Ref : Acta Pharmacol Sin , 21 :124 , 2000
PubMedID: 11263258

Title : Huperzine A improves cognitive deficits caused by chronic cerebral hypoperfusion in rats - Wang_2000_Eur.J.Pharmacol_398_65
Author(s) : Wang LM , Han YF , Tang XC
Ref : European Journal of Pharmacology , 398 :65 , 2000
PubMedID: 10856449

Title : Protection against ischemic injury in primary cultured mouse astrocytes by bis(7)-tacrine, a novel acetylcholinesterase inhibitor [corrected] - Wu_2000_Neurosci.Lett_288_95
Author(s) : Wu DC , Xiao XQ , Ng AK , Chen PM , Chung W , Lee NT , Carlier PR , Pang YP , Yu AC , Han YF
Ref : Neuroscience Letters , 288 :95 , 2000
PubMedID: 10876069

Title : Bis(7)-tacrine, a promising anti-Alzheimer's agent, reduces hydrogen peroxide-induced injury in rat pheochromocytoma cells: comparison with tacrine - Xiao_2000_Neurosci.Lett_290_197
Author(s) : Xiao XQ , Lee NT , Carlier PR , Pang Y , Han YF
Ref : Neuroscience Letters , 290 :197 , 2000
PubMedID: 10963897

Title : Protective effects of huperzine A on beta-amyloid(25-35) induced oxidative injury in rat pheochromocytoma cells - Xiao_2000_Neurosci.Lett_286_155
Author(s) : Xiao XQ , Wang R , Han YF , Tang XC
Ref : Neuroscience Letters , 286 :155 , 2000
PubMedID: 10832008

Title : Bis(7)-tacrine, a novel dimeric AChE inhibitor, is a potent GABA(A) receptor antagonist - Li_1999_Neuroreport_10_795
Author(s) : Li CY , Wang H , Xue H , Carlier PR , Hui KM , Pang YP , Li ZW , Han YF
Ref : Neuroreport , 10 :795 , 1999
PubMedID: 10208550

Title : Effects of bis(7)-tacrine, a novel anti-Alzheimer's agent, on rat brain AChE - Wang_1999_Neuroreport_10_789
Author(s) : Wang H , Carlier PR , Ho WL , Wu DC , Lee NT , Li CP , Pang YP , Han YF
Ref : Neuroreport , 10 :789 , 1999
PubMedID: 10208549

Title : Attenuation of scopolamine-induced deficits in navigational memory performance in rats by bis(7)-tacrine, a novel dimeric AChE inhibitor - Wang_1999_Zhongguo.Yao.Li.Xue.Bao_20_211
Author(s) : Wang H , Carlier PR , Ho WL , Lee NT , Pang YP , Han YF
Ref : Zhongguo Yao Li Xue Bao , 20 :211 , 1999
PubMedID: 10452094

Title : Evaluation of short-tether bis-THA AChE inhibitors. A further test of the dual binding site hypothesis - Carlier_1999_Bioorg.Med.Chem_7_351
Author(s) : Carlier PR , Han YF , Chow ES , Li CP , Wang H , Lieu TX , Wong HS , Pang YP
Ref : Bioorganic & Medicinal Chemistry , 7 :351 , 1999
PubMedID: 10218828

Title : Dual-site binding of bivalent 4-aminopyridine- and 4-aminoquinoline-based AChE inhibitors: contribution of the hydrophobic alkylene tether to monomer and dimer affinities - Han_1999_Bioorg.Med.Chem_7_2569
Author(s) : Han YF , Li CP , Chow E , Wang H , Pang YP , Carlier PR
Ref : Bioorganic & Medicinal Chemistry , 7 :2569 , 1999
PubMedID: 10632067