| Title : Validation of a highly sensitive HaloTag-based assay to evaluate the potency of a novel class of allosteric beta-Galactosidase correctors - Rudinskiy_2023_PLoS.One_18_e0294437 |
| Author(s) : Rudinskiy M , Pons-Vizcarra M , Solda T , Fregno I , Bergmann TJ , Ruano A , Delgado A , Morales S , Barril X , Bellotto M , Cubero E , Garcia-Collazo AM , Perez-Carmona N , Molinari M |
| Ref : PLoS ONE , 18 :e0294437 , 2023 |
| Abstract : |
| PubMedSearch : Rudinskiy_2023_PLoS.One_18_e0294437 |
| PubMedID: 38019733 |
| Title : New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties - Leon_2008_Bioorg.Med.Chem_16_7759 |
| Author(s) : Leon R , de los Rios C , Marco-Contelles J , Huertas O , Barril X , Luque FJ , Lopez MG , Garcia AG , Villarroya M |
| Ref : Bioorganic & Medicinal Chemistry , 16 :7759 , 2008 |
| Abstract : |
| PubMedSearch : Leon_2008_Bioorg.Med.Chem_16_7759 |
| PubMedID: 18640842 |
| Title : Rational design of reversible acetylcholinesterase inhibitors - Barril_2002_Mini.Rev.Med.Chem_2_27 |
| Author(s) : Barril X , Kalko SG , Orozco M , Luque FJ |
| Ref : Mini Rev Med Chem , 2 :27 , 2002 |
| Abstract : |
| PubMedSearch : Barril_2002_Mini.Rev.Med.Chem_2_27 |
| PubMedID: 12369955 |
| Title : 3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 A resolution: kinetic and molecular dynamic correlates - Dvir_2002_Biochemistry_41_2970 |
| Author(s) : Dvir H , Wong DM , Harel M , Barril X , Orozco M , Luque FJ , Munoz-Torrero D , Camps P , Rosenberry TL , Silman I , Sussman JL |
| Ref : Biochemistry , 41 :2970 , 2002 |
| Abstract : |
| PubMedSearch : Dvir_2002_Biochemistry_41_2970 |
| PubMedID: 11863435 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Towards improved acetylcholinesterase inhibitors: an structural and computational approach - Barril_2001_Mini.Rev.Med.Chem_1_255 |
| Author(s) : Barril X , Orozco M |
| Ref : Mini Rev Med Chem , 1 :255 , 2001 |
| Abstract : |
| PubMedSearch : Barril_2001_Mini.Rev.Med.Chem_1_255 |
| PubMedID: 12369972 |
| Title : Synthesis, in Vitro Pharmacology, and Molecular Modeling of syn-Huprines as Acetylcholinesterase Inhibitors - Camps_2001_J.Med.Chem_44_4733 |
| Author(s) : Camps P , Gomez E , Munoz-Torrero D , Badia A , Vivas NM , Barril X , Orozco M , Luque FJ |
| Ref : Journal of Medicinal Chemistry , 44 :4733 , 2001 |
| Abstract : |
| PubMedSearch : Camps_2001_J.Med.Chem_44_4733 |
| PubMedID: 11741490 |
| Title : New tacrine-huperzine A hybrids (huprines): highly potent tight-binding acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease - Camps_2000_J.Med.Chem_43_4657 |
| Author(s) : Camps P , El Achab R , Morral J , Munoz-Torrero D , Badia A , Banos JE , Vivas NM , Barril X , Orozco M , Luque FJ |
| Ref : Journal of Medicinal Chemistry , 43 :4657 , 2000 |
| Abstract : |
| PubMedSearch : Camps_2000_J.Med.Chem_43_4657 |
| PubMedID: 11101357 |
| Title : Predicting relative binding free energies of tacrine-huperzine A hybrids as inhibitors of acetylcholinesterase - Barril_1999_J.Med.Chem_42_5110 |
| Author(s) : Barril X , Orozco M , Luque FJ |
| Ref : Journal of Medicinal Chemistry , 42 :5110 , 1999 |
| Abstract : |
| PubMedSearch : Barril_1999_J.Med.Chem_42_5110 |
| PubMedID: 10602696 |
| Title : Synthesis, in vitro pharmacology, and molecular modeling of very potent tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease - Camps_1999_J.Med.Chem_42_3227 |
| Author(s) : Camps P , El Achab R , Gorbig DM , Morral J , Munoz-Torrero D , Badia A , Eladi Banos J , Vivas NM , Barril X , Orozco M , Luque FJ |
| Ref : Journal of Medicinal Chemistry , 42 :3227 , 1999 |
| Abstract : |
| PubMedSearch : Camps_1999_J.Med.Chem_42_3227 |
| PubMedID: 10464010 |