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Family Report for: CarbLipBact_1

CarbLipBact_1



Relationship
Block X
Parent Family : Hydrolase_4

Comment
PIRSF017388 Members of this group are esterases, lipases, and (possibly) other hydrolases of the alpha/beta hydrolase fold. The Bacillus stearothermophilus member, Est, has been characterized as a carboxylesterase (EC 3.1.1.1) involved in the detoxification of xenobiotics, and the Bacillus sp. member has been characterized as monoacylglycerol lipase. This family correspond to family XIII of the classification of Arpigny and Jaeger 1999. Family XIII was introduced by Ewis et al.(2004) and Liu et al. (2004). The closest family is Monoglyceridelipase_lysophospholip. The family XIII contains LipS Chow et al.. This family is composed of two sub families with different set of salt-bridges important for thermostability Charbonneau et al. (due to simultaneous publication of new families this family was numbered XV but really is a subset of familly XIII. See notice of this paper in Plos One)

Database
Sequences
Interpro
|
IPR012354 (Esterase/lipase)
PIRSF
|
Pdoc
|
PFam
|
Prints
|
Prosite
|
EC at KEGG
|
EC at EXPASY
|


Peptide in
|Fasta
Nucleotide in
|Fasta
Alignment with Multalin
|Text only/graphic display
Seed alignment with MAFFT
|No colour/coloured with Mview
Alignment with MAFFT
|No colour/coloured with Mview
Dendrogram
|Graphical display, obtained with the dnd file produced by Clustalw

References
9 more
    Title: A novel alkaliphilic bacillus esterase belongs to the 13(th) bacterial lipolytic enzyme family
    Rao L, Xue Y, Zheng Y, Lu JR, Ma Y
    Ref: PLoS ONE, 8:e60645, 2013 : PubMed

            

    Title: Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase
    Rengachari S, Aschauer P, Schittmayer M, Mayer N, Gruber K, Breinbauer R, Birner-Gruenberger R, Dreveny I, Oberer M
    Ref: Journal of Biological Chemistry, 288:31093, 2013 : PubMed

            

    Title: Molecular cloning and characterization of two thermostable carboxyl esterases from Geobacillus stearothermophilus
    Ewis HE, Abdelal AT, Lu CD
    Ref: Gene, 329:187, 2004 : PubMed

            

Other Papers


No structure scheme yet for this family

Structures in CarbLipBact_1 family (10)

Genes Proteins in CarbLipBact_1 family (265)

No fragments
Substrates of some enzymes in the CarbLipBact_1 family (2)

Inhibitors of some enzymes in the CarbLipBact_1 family (1)



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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