Gene_locus Report for: neucr-B7H23.190

Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)(strain FGSC 2508 / ATCC MYA-4615 / P0657), (strain FGSC 2509 / P0656)

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Fungi: N E > Dikarya: N E > Ascomycota: N E > saccharomyceta: N E > Pezizomycotina: N E > leotiomyceta: N E > sordariomyceta: N E > Sordariomycetes: N E > Sordariomycetidae: N E > Sordariales: N E > Sordariaceae: N E > Neurospora: N E > Neurospora crassa: N E

Title: The genome sequence of the filamentous fungus Neurospora crassa
Galagan JE, Calvo SE, Borkovich KA, Selker EU, Read ND, Jaffe D, FitzHugh W, Ma LJ, Smirnov S and Birren B <67 more author(s)> Galagan JE, Calvo SE, Borkovich KA, Selker EU, Read ND, Jaffe D, FitzHugh W, Ma LJ, Smirnov S, Purcell S, Rehman B, Elkins T, Engels R, Wang S, Nielsen CB, Butler J, Endrizzi M, Qui D, Ianakiev P, Bell-Pedersen D, Nelson MA, Werner-Washburne M, Selitrennikoff CP, Kinsey JA, Braun EL, Zelter A, Schulte U, Kothe GO, Jedd G, Mewes W, Staben C, Marcotte E, Greenberg D, Roy A, Foley K, Naylor J, Stange-Thomann N, Barrett R, Gnerre S, Kamal M, Kamvysselis M, Mauceli E, Bielke C, Rudd S, Frishman D, Krystofova S, Rasmussen C, Metzenberg RL, Perkins DD, Kroken S, Cogoni C, Macino G, Catcheside D, Li W, Pratt RJ, Osmani SA, DeSouza CP, Glass L, Orbach MJ, Berglund JA, Voelker R, Yarden O, Plamann M, Seiler S, Dunlap J, Radford A, Aramayo R, Natvig DO, Alex LA, Mannhaupt G, Ebbole DJ, Freitag M, Paulsen I, Sachs MS, Lander ES, Nusbaum C, Birren B (- 67)
Ref: Nature, 422:859, 2003 : PubMed
Abstract


ESTHER: Galagan_2003_Nature_422_859
PubMedSearch: Galagan 2003 Nature 422 859
PubMedID: 12712197
Gene_locus related to this paper: neucr-5E6.090, neucr-64C2.080, neucr-90C4.300, neucr-a7uw78, neucr-a7uwh6, neucr-a7uwy7, neucr-apth1, neucr-ATG15, neucr-B7H23.190, neucr-B11O8.160, neucr-B13B3.090, neucr-B14D6.130, neucr-B18E6.050, neucr-B19A17.360, neucr-B23G1.090, neucr-CBPYA, neucr-MET5, neucr-NCU00292.1, neucr-NCU00350.1, neucr-NCU00536.1, neucr-NCU00825.1, neucr-NCU02148.1, neucr-NCU02679.1, neucr-NCU02904.1, neucr-NCU02924.1, neucr-NCU03158.1, neucr-NCU04930.1, neucr-NCU06332.1, neucr-NCU06573.1, neucr-NCU07081.1, neucr-NCU07415.1, neucr-NCU07909.1, neucr-NCU08752.1, neucr-NCU09575.1, neucr-NCU10022.1, neucr-ppme1, neucr-q6mfs7, neucr-q7rxb4, neucr-q7rxv5, neucr-q7ry06, neucr-q7ryd2, neucr-q7rzk2, neucr-q7s0g7, neucr-q7s1x0, neucr-q7s2b3, neucr-q7s2c5, neucr-q7s2p4, neucr-q7s2u9, neucr-q7s3c6, neucr-q7s3c8, neucr-q7s3m2, neucr-q7s4e3, neucr-q7s4f8, neucr-q7s4j4, neucr-q7s5d6, neucr-q7s5m2, neucr-q7s5v8, neucr-q7s6c5, neucr-q7s8h2, neucr-q7s070, neucr-q7s082, neucr-q7s134, neucr-q7s216, neucr-q7s259, neucr-q7s260, neucr-q7s283, neucr-q7s512, neucr-q7s736, neucr-q7s828, neucr-q7s897, neucr-q7sbf9, neucr-q7sbn0, neucr-q7scr4, neucr-q7sdw5, neucr-q7sdx9, neucr-q7se51, neucr-q7sea3, neucr-q7sez8, neucr-q7sff7, neucr-q7sga3, neucr-q7sgj0, neucr-q7sgp3, neucr-q7sha3, neucr-q7sha5, neucr-q7shu8, neucr-q9p6a7, neucr-q872l1, neucr-f5hbr2, neucr-q7ry64

Abstract

Neurospora crassa is a central organism in the history of twentieth-century genetics, biochemistry and molecular biology. Here, we report a high-quality draft sequence of the N. crassa genome. The approximately 40-megabase genome encodes about 10,000 protein-coding genes--more than twice as many as in the fission yeast Schizosaccharomyces pombe and only about 25% fewer than in the fruitfly Drosophila melanogaster. Analysis of the gene set yields insights into unexpected aspects of Neurospora biology including the identification of genes potentially associated with red light photobiology, genes implicated in secondary metabolism, and important differences in Ca2+ signalling as compared with plants and animals. Neurospora possesses the widest array of genome defence mechanisms known for any eukaryotic organism, including a process unique to fungi called repeat-induced point mutation (RIP). Genome analysis suggests that RIP has had a profound impact on genome evolution, greatly slowing the creation of new genes through genomic duplication and resulting in a genome with an unusually low proportion of closely related genes.



        

Title: What's in the genome of a filamentous fungus? Analysis of the Neurospora genome sequence
Mannhaupt G, Montrone C, Haase D, Mewes HW, Aign V, Hoheisel JD, Fartmann B, Nyakatura G, Kempken F and Schulte U <1 more author(s)> Mannhaupt G, Montrone C, Haase D, Mewes HW, Aign V, Hoheisel JD, Fartmann B, Nyakatura G, Kempken F, Maier J, Schulte U (- 1)
Ref: Nucleic Acids Research, 31:1944, 2003 : PubMed
Abstract


ESTHER: Mannhaupt_2003_Nucleic.Acids.Res_31_1944
PubMedSearch: Mannhaupt 2003 Nucleic.Acids.Res 31 1944
PubMedID: 12655011
Gene_locus related to this paper: neucr-apth1, neucr-B7H23.190, neucr-ppme1

Abstract

The German Neurospora Genome Project has assembled sequences from ordered cosmid and BAC clones of linkage groups II and V of the genome of Neurospora crassa in 13 and 12 contigs, respectively. Including additional sequences located on other linkage groups a total of 12 Mb were subjected to a manual gene extraction and annotation process. The genome comprises a small number of repetitive elements, a low degree of segmental duplications and very few paralogous genes. The analysis of the 3218 identified open reading frames provides a first overview of the protein equipment of a filamentous fungus. Significantly, N.crassa possesses a large variety of metabolic enzymes including a substantial number of enzymes involved in the degradation of complex substrates as well as secondary metabolism. While several of these enzymes are specific for filamentous fungi many are shared exclusively with prokaryotes.