Gene_Locus Report

Biblio print

Add to basket

Go to basket

Tree Display

AceDB Schema

XML Display

Feedback

Gene_locus Report for: trede-Q93EK3

Treponema denticola opdb protease II (EC 3.4.21.83)

Comment
Other strains: Treponema denticola (strains ATCC 35405 / CIP 103919 / DSM 14222; F0402)


Relationship
Family|S9N_PREPL_Peptidase_S9
Block| X
Position in NCBI Life Tree|Treponema denticola
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Bacteria: N E > Spirochaetes: N E > Spirochaetia: N E > Spirochaetales: N E > Spirochaetaceae: N E > Treponema: N E > Treponema denticola: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acid identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
2 Genbank : AF355459, AE017253
3 UniProt : Q93EK3, Q73KS7, E9S340
3 UniProt : Q93EK3, Q73KS7, E9S340
3 Interpro : Q93EK3, Q73KS7, E9S340
3 Pfam : Q93EK3, Q73KS7, E9S340
3 PIRSF : Q93EK3, Q73KS7, E9S340
3 SUPERFAM : Q93EK3, Q73KS7, E9S340
Sequence
Graphical view for this peptide sequence: trede-Q93EK3
Colored MSA for S9N_PREPL_Peptidase_S9 (raw)
MKQSDSEKPPIAGIKETRFEKFGKTRIDNYYWLKDKTDKKVIDYLNAENA
YTDKIMASSKDLQKSIYDEIVGRIKEDDETYPVFENGYYYYNRVEKGKQY
RTYCRKKASLDAAEEIIFDVNKMAEGKQAFIFDDYVVSPDNKKACYFYNE
TGSFAEFILKIRDLETGKDIGFSYDGAVTAAWASDSKTLFYSAIDSTLRS
SKVFRQKLDEEKGTLVYEEKDVKYSCYVHETKTKEFIFISSSSSTTSEER
FIYADKPEEEFKIFLPRVKDTEYSVYPHKEKFFIGYKDKQNLNGKIYSAP
RSSYSDKSTWKEERAHDENVRIEDVSVFESYLVLELRKNGLIEIEIKSLK
NGEVKNISFPEPVYTAYLGANPEYVSDKVRYIYTSLNRPSSVYDYDILTG
KSVLLKQQEVPSGFNPDDYTVERLWATAQDGVKVPMAAVYKKGLVKDGSS
PALLYSYGSYGSSSDAFFSPSVYSLVERGFVYVVAQIRGGSDMGEKWYED
GKLLKKKNTFTDFIACAEHLISQKYTSSDKLAIMGGSAGGLLMGAVTNMR
PDLFHSVVAVVPFIDVVTTMLDDSLPLTTGEYEEWGNPNEEEYYNYMLSY
SPYDNIEAKNYPHIFVTGGLNDSQVLFHEPAKYTAKLRAKKTGDNILILR
MNMDSGHGGATGRYDKIKDIAFEQAFILNMVGINK
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MKQSDSEKPPIAGIKETRFEKFGKTRIDNYYWLKDKTDKKVIDYLNAENA
YTDKIMASSKDLQKSIYDEIVGRIKEDDETYPVFENGYYYYNRVEKGKQY
RTYCRKKASLDAAEEIIFDVNKMAEGKQAFIFDDYVVSPDNKKACYFYNE
TGSFAEFILKIRDLETGKDIGFSYDGAVTAAWASDSKTLFYSAIDSTLRS
SKVFRQKLDEEKGTLVYEEKDVKYSCYVHETKTKEFIFISSSSSTTSEER
FIYADKPEEEFKIFLPRVKDTEYSVYPHKEKFFIGYKDKQNLNGKIYSAP
RSSYSDKSTWKEERAHDENVRIEDVSVFESYLVLELRKNGLIEIEIKSLK
NGEVKNISFPEPVYTAYLGANPEYVSDKVRYIYTSLNRPSSVYDYDILTG
KSVLLKQQEVPSGFNPDDYTVERLWATAQDGVKVPMAAVYKKGLVKDGSS
PALLYSYGSYGSSSDAFFSPSVYSLVERGFVYVVAQIRGGSDMGEKWYED
GKLLKKKNTFTDFIACAEHLISQKYTSSDKLAIMGGSAGGLLMGAVTNMR
PDLFHSVVAVVPFIDVVTTMLDDSLPLTTGEYEEWGNPNEEEYYNYMLSY
SPYDNIEAKNYPHIFVTGGLNDSQVLFHEPAKYTAKLRAKKTGDNILILR
MNMDSGHGGATGRYDKIKDIAFEQAFILNMVGINK


References
    Title: Comparison of the genome of the oral pathogen Treponema denticola with other spirochete genomes
    Seshadri R, Myers GS, Tettelin H, Eisen JA, Heidelberg JF, Dodson RJ, Davidsen TM, DeBoy RT, Fouts DE and Paulsen IT <29 more author(s)>
    Ref: Proc Natl Acad Sci U S A, 101:5646, 2004 : PubMed

            

    Title: The opdB locus encodes the trypsin-like peptidase activity of Treponema denticola
    Fenno JC, Lee SY, Bayer CH, Ning Y
    Ref: Infect Immun, 69:6193, 2001 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer