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Inhibitor Report for: JZP-430

General
Type Carbamate, Morpholine, Sulfur Compound, Thiadiazol
Chemical_Nomenclature (4-morpholin-4-yl-1,2,5-thiadiazol-3-yl) N-cyclooctyl-N-methylcarbamate
Canonical SMILES CN(C1CCCCCCC1)C(=O)OC2=NSN=C2N3CCOCC3
InChI InChI=1S/C16H26N4O3S/c1-19(13-7-5-3-2-4-6-8-13)16(21)23-15-14(17-24-18-15)20-9-11-22-12-10-20/h13H,2-12H2,1H3
InChIKey WKSHMJCYWFOADB-UHFFFAOYSA-N
Other name(s) (4-Morpholin-4-yl-1,2,5-thiadiazol-3-yl) N-cyclooctyl-N-methylcarbamate ; 4-(4-Morpholinyl)-1,2,5-thiadiazol-3-ylN-cyclooctyl-N-methylcarbamate ; CHEMBL3613671 ; SCHEMBL22799434 ; JZP 430 ; ZINC473127446
________________________________________________________________________________________________
MW|354.5
Formula|C16H26N4O3S
CAS_number|1672691-74-5
PubChem|121513897
UniChem|WKSHMJCYWFOADB-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | JZP-430 ligand of proteins in family: ABHD6-Lip
Protein | human-ABHD6

References:
Search PubMed for references concerning: JZP-430
    Title: Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors
    Patel JZ, Nevalainen TJ, Savinainen JR, Adams Y, Laitinen T, Runyon RS, Vaara M, Ahenkorah S, Kaczor AA and Parkkari T <8 more author(s)>
    Ref: ChemMedChem, 10:253, 2015 : PubMed