Gene Locus : human-PLA2G7
Mode of mutation : Natural mutant
Disease : Suceptibility to asthma and atopy, Platelet-activating factor acetylhydrolase (PLA2G7) deficiency (PAFAD) coronary artery disease risk factor
Summary :
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification :
Torpedo_number : No torpedo number
Kinetic Parameter : No kinetic parameter
News : No news
Comment :
p.Val379Ala GTA->GCA rs1051931
| Title : Association Lp-PLA2 Gene Polymorphisms with Coronary Heart Disease - Ma_2022_Dis.Markers_2022_9775699 |
| Author(s) : Ma S , Ding L , Cai M , Chen L , Yan B , Yang J |
| Ref : Dis Markers , 2022 :9775699 , 2022 |
| Abstract : |
| PubMedSearch : Ma_2022_Dis.Markers_2022_9775699 |
| PubMedID: 35818585 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : The rs1051931 G>A Polymorphism in the PLA2G7 Gene Confers Resistance to Immunoglobulin Therapy in Kawasaki Disease in a Southern Chinese Population - Gu_2020_Front.Pediatr_8_338 |
| Author(s) : Gu X , Lin W , Xu Y , Che D , Tan Y , Lu Z , Pi L , Fu L , Zhou H , Jiang Z |
| Ref : Front Pediatr , 8 :338 , 2020 |
| Abstract : |
| PubMedSearch : Gu_2020_Front.Pediatr_8_338 |
| PubMedID: 32656171 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Associations between four types of single-nucleotide polymorphisms in PLA2G7 gene and clinical atherosclerosis: a meta-analysis - Santoso_2017_Am.J.Cardiovasc.Dis_7_122 |
| Author(s) : Santoso A , Maulana R , Alzahra F , Maghfirah I , Putrinarita AD , Heriansyah T |
| Ref : Am J Cardiovasc Dis , 7 :122 , 2017 |
| Abstract : |
| PubMedSearch : Santoso_2017_Am.J.Cardiovasc.Dis_7_122 |
| PubMedID: 29348973 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Correlations Between LP-PLA2 Gene Polymorphisms and Susceptibility and Severity of Acute Pancreatitis in a Chinese Population - Ma_2017_Genet.Test.Mol.Biomarkers_21_206 |
| Author(s) : Ma M , Zhai CX , Sun CX |
| Ref : Genet Test Mol Biomarkers , 21 :206 , 2017 |
| Abstract : |
| PubMedSearch : Ma_2017_Genet.Test.Mol.Biomarkers_21_206 |
| PubMedID: 28332853 |
| Title : Effect of the R92H and A379V genotypes of platelet-activating factor acetylhydrolase on its enzyme activity, oxidative stress and metabolic profile in Chinese women with polycystic ovary syndrome - Zhang_2017_Lipids.Health.Dis_16_57 |
| Author(s) : Zhang R , Song Q , Liu H , Bai H , Zhang Y , Liu Q , Guan L , Fan P |
| Ref : Lipids Health Dis , 16 :57 , 2017 |
| Abstract : |
| PubMedSearch : Zhang_2017_Lipids.Health.Dis_16_57 |
| PubMedID: 28320416 |
| Title : Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 genetic polymorphisms with the platelet activity in Chinese ischemic stroke patients receiving aspirin therapy - Peng_2016_Acta.Pharmacol.Sin_37_1442 |
| Author(s) : Peng LL , Zhao YQ , Zhou ZY , Jin J , Zhao M , Chen XM , Chen LY , Cai YF , Li JL , Huang M |
| Ref : Acta Pharmacol Sin , 37 :1442 , 2016 |
| Abstract : |
| PubMedSearch : Peng_2016_Acta.Pharmacol.Sin_37_1442 |
| PubMedID: 27641736 |
| Title : Association between Ala379Val polymorphism of lipoprotein-associated phospholipase A2 and migraine without aura in Iranian population - Haghdoost_2016_Iran.J.Neurol_15_80 |
| Author(s) : Haghdoost F , Gharzi M , Faez F , Hosseinzadeh E , Tajaddini M , Ra Ei L , Asgari F , Banihashemi M , Masjedi SS , Zandifar A , Haghjooy-Javanmard S |
| Ref : Iran Journal of Neurology , 15 :80 , 2016 |
| Abstract : |
| PubMedSearch : Haghdoost_2016_Iran.J.Neurol_15_80 |
| PubMedID: 27326362 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Nonsynonymous polymorphisms in PLA2G7 gene are associated with the risk of coronary heart disease in a southern Chinese population - Hong_2015_Mamm.Genome_26_191 |
| Author(s) : Hong M , Zhang M , Lu X |
| Ref : Mamm Genome , 26 :191 , 2015 |
| Abstract : |
| PubMedSearch : Hong_2015_Mamm.Genome_26_191 |
| PubMedID: 25690150 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Association between lipoprotein-associated phospholipase A2 gene polymorphism and coronary artery disease in the Chinese Han population - Li_2011_Ann.Hum.Genet_75_605 |
| Author(s) : Li L , Qi L , Lv N , Gao Q , Cheng Y , Wei Y , Ye J , Yan X , Dang A |
| Ref : Ann Hum Genet , 75 :605 , 2011 |
| Abstract : |
| PubMedSearch : Li_2011_Ann.Hum.Genet_75_605 |
| PubMedID: 21834908 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : PLA2G7 gene polymorphisms and coronary heart disease risk: a meta-analysis - Wang_2010_Thromb.Res_126_498 |
| Author(s) : Wang Q , Hao Y , Mo X , Wang L , Lu X , Huang J , Cao J , Li H , Gu D |
| Ref : Thromb Res , 126 :498 , 2010 |
| Abstract : |
| PubMedSearch : Wang_2010_Thromb.Res_126_498 |
| PubMedID: 20926117 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Genetic variants and haplotypes of lipoprotein associated phospholipase A2 and their influence on cardiovascular disease (The Ludwigshafen Risk and Cardiovascular Health Study) - Hoffmann_2009_J.Thromb.Haemost_7_41 |
| Author(s) : Hoffmann MM , Winkler K , Renner W , Winkelmann BR , Seelhorst U , Wellnitz B , Boehm BO , Marz W |
| Ref : J Thromb Haemost , 7 :41 , 2009 |
| Abstract : |
| PubMedSearch : Hoffmann_2009_J.Thromb.Haemost_7_41 |
| PubMedID: 18983494 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Inter-individual variability of plasma PAF-acetylhydrolase activity in ARDS patients and PAFAH genotype - Li_2009_J.Clin.Pharm.Ther_34_447 |
| Author(s) : Li S , Stuart L , Zhang Y , Meduri GU , Umberger R , Yates CR |
| Ref : J Clin Pharm Ther , 34 :447 , 2009 |
| Abstract : |
| PubMedSearch : Li_2009_J.Clin.Pharm.Ther_34_447 |
| PubMedID: 19583678 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Comprehensive genetic analysis of the platelet activating factor acetylhydrolase (PLA2G7) gene and cardiovascular disease in case-control and family datasets - Sutton_2008_Hum.Mol.Genet_17_1318 |
| Author(s) : Sutton BS , Crosslin DR , Shah SH , Nelson SC , Bassil A , Hale AB , Haynes C , Goldschmidt-Clermont PJ , Vance JM , Seo D , Kraus WE , Gregory SG , Hauser ER |
| Ref : Hum Mol Genet , 17 :1318 , 2008 |
| Abstract : |
| PubMedSearch : Sutton_2008_Hum.Mol.Genet_17_1318 |
| PubMedID: 18204052 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Association of sixty-one non-synonymous polymorphisms in forty-one hypertension candidate genes with blood pressure variation and hypertension - Kokubo_2006_Hypertens.Res_29_611 |
| Author(s) : Kokubo Y , Tomoike H , Tanaka C , Banno M , Okuda T , Inamoto N , Kamide K , Kawano Y , Miyata T |
| Ref : Hypertens Res , 29 :611 , 2006 |
| Abstract : |
| PubMedSearch : Kokubo_2006_Hypertens.Res_29_611 |
| PubMedID: 17137217 |
| Gene_locus related to this paper: human-LIPC |
| Title : Platelet-activating factor-acetylhydrolase and PAF-receptor gene haplotypes in relation to future cardiovascular event in patients with coronary artery disease - Ninio_2004_Hum.Mol.Genet_13_1341 |
| Author(s) : Ninio E , Tregouet D , Carrier JL , Stengel D , Bickel C , Perret C , Rupprecht HJ , Cambien F , Blankenberg S , Tiret L |
| Ref : Hum Mol Genet , 13 :1341 , 2004 |
| Abstract : |
| PubMedSearch : Ninio_2004_Hum.Mol.Genet_13_1341 |
| PubMedID: 15115767 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Association between the Ala379Val variant of the lipoprotein associated phospholipase A2 and risk of myocardial infarction in the north and south of Europe - Abuzeid_2003_Atherosclerosis_168_283 |
| Author(s) : Abuzeid AM , Hawe E , Humphries SE , Talmud PJ |
| Ref : Atherosclerosis , 168 :283 , 2003 |
| Abstract : |
| PubMedSearch : Abuzeid_2003_Atherosclerosis_168_283 |
| PubMedID: 12801611 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : The Ile198Thr and Ala379Val variants of plasmatic PAF-acetylhydrolase impair catalytical activities and are associated with atopy and asthma - Kruse_2000_Am.J.Hum.Genet_66_1522 |
| Author(s) : Kruse S , Mao XQ , Heinzmann A , Blattmann S , Roberts MH , Braun S , Gao PS , Forster J , Kuehr J , Hopkin JM , Shirakawa T , Deichmann KA |
| Ref : American Journal of Human Genetics , 66 :1522 , 2000 |
| Abstract : |
| PubMedSearch : Kruse_2000_Am.J.Hum.Genet_66_1522 |
| PubMedID: 10733466 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Systematic screening of the LDL-PLA2 gene for polymorphic variants and case-control analysis in schizophrenia - Bell_1997_Biochem.Biophys.Res.Commun_241_630 |
| Author(s) : Bell R , Collier DA , Rice SQ , Roberts GW , Macphee CH , Kerwin RW , Price J , Gloger IS |
| Ref : Biochemical & Biophysical Research Communications , 241 :630 , 1997 |
| Abstract : |
| PubMedSearch : Bell_1997_Biochem.Biophys.Res.Commun_241_630 |
| PubMedID: 9434759 |
| Gene_locus related to this paper: human-PLA2G7 |