| Title : Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes - Dominguez_2014_Nat.Chem.Biol_10_113 |
| Author(s) : Dominguez E , Galmozzi A , Chang JW , Hsu KL , Pawlak J , Li W , Godio C , Thomas J , Partida D , Niessen S , O'Brien PE , Russell AP , Watt MJ , Nomura DK , Cravatt BF , Saez E |
| Ref : Nat Chemical Biology , 10 :113 , 2014 |
| Abstract : |
| PubMedSearch : Dominguez_2014_Nat.Chem.Biol_10_113 |
| PubMedID: 24362705 |
| Gene_locus related to this paper: human-CES3 , mouse-Ces1d |
| Title : Chemoproteomic discovery of AADACL1 as a regulator of human platelet activation - Holly_2013_Chem.Biol_20_1125 |
| Author(s) : Holly SP , Chang JW , Li W , Niessen S , Phillips RM , Piatt R , Black JL , Smith MC , Boulaftali Y , Weyrich AS , Bergmeier W , Cravatt BF , Parise LV |
| Ref : Chemical Biology , 20 :1125 , 2013 |
| Abstract : |
| PubMedSearch : Holly_2013_Chem.Biol_20_1125 |
| PubMedID: 23993462 |
| Gene_locus related to this paper: human-NCEH1 |
| Title : Competitive activity-based protein profiling identifies aza-beta-lactams as a versatile chemotype for serine hydrolase inhibition - Zuhl_2012_J.Am.Chem.Soc_134_5068 |
| Author(s) : Zuhl AM , Mohr JT , Bachovchin DA , Niessen S , Hsu KL , Berlin JM , Dochnahl M , Lopez-Alberca MP , Fu GC , Cravatt BF |
| Ref : J Am Chem Soc , 134 :5068 , 2012 |
| Abstract : |
| PubMedSearch : Zuhl_2012_J.Am.Chem.Soc_134_5068 |
| PubMedID: 22400490 |
| Gene_locus related to this paper: human-ABHD10 |
| Title : Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates - Chang_2012_Chem.Biol_19_579 |
| Author(s) : Chang JW , Niphakis MJ , Lum KM , Cognetta AB, 3rd , Wang C , Matthews ML , Niessen S , Buczynski MW , Parsons LH , Cravatt BF |
| Ref : Chemical Biology , 19 :579 , 2012 |
| Abstract : |
| PubMedSearch : Chang_2012_Chem.Biol_19_579 |
| PubMedID: 22542104 |
| Gene_locus related to this paper: human-MGLL |
| Title : Metabolomics annotates ABHD3 as a physiologic regulator of medium-chain phospholipids - Long_2011_Nat.Chem.Biol_7_763 |
| Author(s) : Long JZ , Cisar JS , Milliken D , Niessen S , Wang C , Trauger SA , Siuzdak G , Cravatt BF |
| Ref : Nat Chemical Biology , 7 :763 , 2011 |
| Abstract : |
| PubMedSearch : Long_2011_Nat.Chem.Biol_7_763 |
| PubMedID: 21926997 |
| Gene_locus related to this paper: human-ABHD3 , mouse-abhd3 |
| Title : Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula - Jones_2011_Proc.Natl.Acad.Sci.U.S.A_108_8815 |
| Author(s) : Jones AC , Monroe EA , Podell S , Hess WR , Klages S , Esquenazi E , Niessen S , Hoover H , Rothmann M , Lasken RS , Yates JR, 3rd , Reinhardt R , Kube M , Burkart MD , Allen EE , Dorrestein PC , Gerwick WH , Gerwick L |
| Ref : Proc Natl Acad Sci U S A , 108 :8815 , 2011 |
| Abstract : |
| PubMedSearch : Jones_2011_Proc.Natl.Acad.Sci.U.S.A_108_8815 |
| PubMedID: 21555588 |
| Gene_locus related to this paper: 9cyan-f4xvi1 , 9cyan-f4xkf8 , 9cyan-f4y3s0 |
| Title : Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors - Adibekian_2011_Nat.Chem.Biol_7_469 |
| Author(s) : Adibekian A , Martin BR , Wang C , Hsu KL , Bachovchin DA , Niessen S , Hoover H , Cravatt BF |
| Ref : Nat Chemical Biology , 7 :469 , 2011 |
| Abstract : |
| PubMedSearch : Adibekian_2011_Nat.Chem.Biol_7_469 |
| PubMedID: 21572424 |
| Title : RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia - Shields_2010_Proc.Natl.Acad.Sci.U.S.A_107_2189 |
| Author(s) : Shields DJ , Niessen S , Murphy EA , Mielgo A , Desgrosellier JS , Lau SK , Barnes LA , Lesperance J , Bouvet M , Tarin D , Cravatt BF , Cheresh DA |
| Ref : Proc Natl Acad Sci U S A , 107 :2189 , 2010 |
| Abstract : |
| PubMedSearch : Shields_2010_Proc.Natl.Acad.Sci.U.S.A_107_2189 |
| PubMedID: 20080647 |
| Gene_locus related to this paper: human-RBBP9 |
| Title : Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis - Nomura_2010_Cell_140_49 |
| Author(s) : Nomura DK , Long JZ , Niessen S , Hoover HS , Ng SW , Cravatt BF |
| Ref : Cell , 140 :49 , 2010 |
| Abstract : |
| PubMedSearch : Nomura_2010_Cell_140_49 |
| PubMedID: 20079333 |
| Gene_locus related to this paper: human-MGLL , mouse-MGLL |
| Title : Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening - Bachovchin_2010_Proc.Natl.Acad.Sci.U.S.A_107_20941 |
| Author(s) : Bachovchin DA , Ji T , Li W , Simon GM , Blankman JL , Adibekian A , Hoover H , Niessen S , Cravatt BF |
| Ref : Proc Natl Acad Sci U S A , 107 :20941 , 2010 |
| Abstract : |
| PubMedSearch : Bachovchin_2010_Proc.Natl.Acad.Sci.U.S.A_107_20941 |
| PubMedID: 21084632 |
| Title : Diversity of serine hydrolase activities of unchallenged and botrytis-infected Arabidopsis thaliana - Kaschani_2009_Mol.Cell.Proteomics_8_1082 |
| Author(s) : Kaschani F , Gu C , Niessen S , Hoover H , Cravatt BF , van der Hoorn RA |
| Ref : Mol Cell Proteomics , 8 :1082 , 2009 |
| Abstract : |
| PubMedSearch : Kaschani_2009_Mol.Cell.Proteomics_8_1082 |
| PubMedID: 19136719 |
| Title : Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling - Hoover_2008_Bioorg.Med.Chem.Lett_18_5838 |
| Author(s) : Hoover HS , Blankman JL , Niessen S , Cravatt BF |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :5838 , 2008 |
| Abstract : |
| PubMedSearch : Hoover_2008_Bioorg.Med.Chem.Lett_18_5838 |
| PubMedID: 18657971 |
| Title : An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling - Chiang_2006_Chem.Biol_13_1041 |
| Author(s) : Chiang KP , Niessen S , Saghatelian A , Cravatt BF |
| Ref : Chemical Biology , 13 :1041 , 2006 |
| Abstract : |
| PubMedSearch : Chiang_2006_Chem.Biol_13_1041 |
| PubMedID: 17052608 |
| Gene_locus related to this paper: human-NCEH1 , mouse-Q8BLF1 |
| Title : Proteomic profiling of metalloprotease activities with cocktails of active-site probes - Sieber_2006_Nat.Chem.Biol_2_274 |
| Author(s) : Sieber SA , Niessen S , Hoover HS , Cravatt BF |
| Ref : Nat Chemical Biology , 2 :274 , 2006 |
| Abstract : |
| PubMedSearch : Sieber_2006_Nat.Chem.Biol_2_274 |
| PubMedID: 16565715 |