| Title : Antioxidant, Antimicrobial, and Bioactive Potential of Two New Haloarchaeal Strains Isolated from Odiel Salterns (Southwest Spain) - Gomez-Villegas_2020_Biology.(Basel)_9_ |
| Author(s) : Gomez-Villegas P , Vigara J , Vila M , Varela J , Barreira L , Leon R |
| Ref : Biology (Basel) , 9 : , 2020 |
| Abstract : |
| PubMedSearch : Gomez-Villegas_2020_Biology.(Basel)_9_ |
| PubMedID: 32962162 |
| Title : Antioxidant, Anti-inflammatory and Neuroprotective Profiles of Novel 1,4-Dihydropyridine Derivatives for the Treatment of Alzheimer's Disease - Michalska_2020_Antioxidants.(Basel)_9_ |
| Author(s) : Michalska P , Mayo P , Fernandez-Mendivil C , Tenti G , Duarte P , Buendia I , Ramos MT , Lopez MG , Menendez JC , Leon R |
| Ref : Antioxidants (Basel) , 9 : , 2020 |
| Abstract : |
| PubMedSearch : Michalska_2020_Antioxidants.(Basel)_9_ |
| PubMedID: 32708053 |
| Title : Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia - Monjas_2017_Eur.J.Med.Chem_130_60 |
| Author(s) : Monjas L , Arce MP , Leon R , Egea J , Perez C , Villarroya M , Lopez MG , Gil C , Conde S , Rodriguez-Franco MI |
| Ref : Eur Journal of Medicinal Chemistry , 130 :60 , 2017 |
| Abstract : |
| PubMedSearch : Monjas_2017_Eur.J.Med.Chem_130_60 |
| PubMedID: 28242552 |
| Title : The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators - Benchekroun_2016_J.Med.Chem_59_9967 |
| Author(s) : Benchekroun M , Romero A , Egea J , Leon R , Michalska P , Buendia I , Jimeno ML , Jun D , Janockova J , Sepsova V , Soukup O , Bautista-Aguilera OM , Refouvelet B , Ouari O , Marco-Contelles J , Ismaili L |
| Ref : Journal of Medicinal Chemistry , 59 :9967 , 2016 |
| Abstract : |
| PubMedSearch : Benchekroun_2016_J.Med.Chem_59_9967 |
| PubMedID: 27736061 |
| Title : Subthreshold Concentrations of Melatonin and Galantamine Improves Pathological AD-Hallmarks in Hippocampal Organotypic Cultures - Buendia_2016_Mol.Neurobiol_53_3338 |
| Author(s) : Buendia I , Parada E , Navarro E , Leon R , Negredo P , Egea J , Lopez MG |
| Ref : Molecular Neurobiology , 53 :3338 , 2016 |
| Abstract : |
| PubMedSearch : Buendia_2016_Mol.Neurobiol_53_3338 |
| PubMedID: 26081146 |
| Title : Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection - Egea_2015_Biochem.Pharmacol_97(4)_463 |
| Author(s) : Egea J , Buendia I , Parada E , Navarro E , Leon R , Lopez MG |
| Ref : Biochemical Pharmacology , 97 :463 , 2015 |
| Abstract : |
| PubMedSearch : Egea_2015_Biochem.Pharmacol_97(4)_463 |
| PubMedID: 26232730 |
| Title : Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase I induction - Navarro_2015_Biochem.Pharmacol_97(4)_473 |
| Author(s) : Navarro E , Buendia I , Parada E , Leon R , Jansen-Duerr P , Pircher H , Egea J , Lopez MG |
| Ref : Biochemical Pharmacology , 97 :473 , 2015 |
| Abstract : |
| PubMedSearch : Navarro_2015_Biochem.Pharmacol_97(4)_473 |
| PubMedID: 26212551 |
| Title : Effects of novel tacripyrines ITH12117 and ITH12118 on rat vas deferens contractions, calcium transients and cholinesterase activity - Pereira_2011_Eur.J.Pharmacol_660_411 |
| Author(s) : Pereira JD , Caricati-Neto A , Miranda-Ferreira R , Smaili SS , Godinho RO , de los Rios C , Leon R , Villaroya M , Samadi A , Marco-Contelles J , Jurkiewicz NH , Garcia AG , Jurkiewicz A |
| Ref : European Journal of Pharmacology , 660 :411 , 2011 |
| Abstract : |
| PubMedSearch : Pereira_2011_Eur.J.Pharmacol_660_411 |
| PubMedID: 21497158 |
| Title : N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease - Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224 |
| Author(s) : Gonzalez-Munoz GC , Arce MP , Lopez B , Perez C , Romero A , Del Barrio L , Martin-de-Saavedra MD , Egea J , Leon R , Villarroya M , Lopez MG , Garcia AG , Conde S , Rodriguez-Franco MI |
| Ref : Eur Journal of Medicinal Chemistry , 46 :2224 , 2011 |
| Abstract : |
| PubMedSearch : Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224 |
| PubMedID: 21420206 |
| Title : Synthesis and biological assessment of diversely substituted furo[2,3-b]quinolin-4-amine and pyrrolo[2,3-b]quinolin-4-amine derivatives, as novel tacrine analogues - Martins_2011_Eur.J.Med.Chem_46_6119 |
| Author(s) : Martins C , Carreiras MC , Leon R , de los Rios C , Bartolini M , Andrisano V , Iriepa I , Moraleda I , Galvez E , Garcia M , Egea J , Samadi A , Chioua M , Marco-Contelles J |
| Ref : Eur Journal of Medicinal Chemistry , 46 :6119 , 2011 |
| Abstract : |
| PubMedSearch : Martins_2011_Eur.J.Med.Chem_46_6119 |
| PubMedID: 22000936 |
| Title : Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives - de Los Rios_2010_J.Med.Chem_53_5129 |
| Author(s) : de los Rios C , Egea J , Marco-Contelles J , Leon R , Samadi A , Iriepa I , Moraleda I , Galvez E , Garcia AG , Lopez MG , Villarroya M , Romero A |
| Ref : Journal of Medicinal Chemistry , 53 :5129 , 2010 |
| Abstract : |
| PubMedSearch : de Los Rios_2010_J.Med.Chem_53_5129 |
| PubMedID: 20575555 |
| Title : New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties - Leon_2008_Bioorg.Med.Chem_16_7759 |
| Author(s) : Leon R , de los Rios C , Marco-Contelles J , Huertas O , Barril X , Luque FJ , Lopez MG , Garcia AG , Villarroya M |
| Ref : Bioorganic & Medicinal Chemistry , 16 :7759 , 2008 |
| Abstract : |
| PubMedSearch : Leon_2008_Bioorg.Med.Chem_16_7759 |
| PubMedID: 18640842 |
| Title : Novel multipotent tacrine-dihydropyridine hybrids with improved acetylcholinesterase inhibitory and neuroprotective activities as potential drugs for the treatment of Alzheimer's disease - Marco-Contelles_2006_J.Med.Chem_49_7607 |
| Author(s) : Marco-Contelles J , Leon R , de los Rios C , Guglietta A , Terencio J , Lopez MG , Garcia AG , Villarroya M |
| Ref : Journal of Medicinal Chemistry , 49 :7607 , 2006 |
| Abstract : |
| PubMedSearch : Marco-Contelles_2006_J.Med.Chem_49_7607 |
| PubMedID: 17181144 |
| Title : Synthesis and biological evaluation of new 4H-pyrano[2,3-b]quinoline derivatives that block acetylcholinesterase and cell calcium signals, and cause neuroprotection against calcium overload and free radicals - Marco-Contelles_2006_Eur.J.Med.Chem_41_1464 |
| Author(s) : Marco-Contelles J , Leon R , Lopez MG , Garcia AG , Villarroya M |
| Ref : Eur Journal of Medicinal Chemistry , 41 :1464 , 2006 |
| Abstract : |
| PubMedSearch : Marco-Contelles_2006_Eur.J.Med.Chem_41_1464 |
| PubMedID: 17030484 |
| Title : Synthesis, acetylcholinesterase inhibition and neuroprotective activity of new tacrine analogues - Leon_2005_Bioorg.Med.Chem_13_1167 |
| Author(s) : Leon R , Marco-Contelles J , Garcia AG , Villarroya M |
| Ref : Bioorganic & Medicinal Chemistry , 13 :1167 , 2005 |
| Abstract : |
| PubMedSearch : Leon_2005_Bioorg.Med.Chem_13_1167 |
| PubMedID: 15670925 |
| Title : ITH4012 (ethyl 5-amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylat e), a novel acetylcholinesterase inhibitor with calcium promotor and neuroprotective properties - Orozco_2004_J.Pharmacol.Exp.Ther_310_987 |
| Author(s) : Orozco C , de los Rios C , Arias E , Leon R , Garcia AG , Marco JL , Villarroya M , Lopez MG |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 310 :987 , 2004 |
| Abstract : |
| PubMedSearch : Orozco_2004_J.Pharmacol.Exp.Ther_310_987 |
| PubMedID: 15111641 |