mouse-Ces2a

Mus musculus (Mouse) Protein Ces2a Ces6 carboxylesterase 6 (Intestine, liver) AI266984

Comment

Hydrolyse pyrethroids Stok et al

Relationship

Family : Carb_B_Chordata

Block : C

Position in NCBI Life Tree : Mus musculus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Glires N E > Rodentia N E > Myomorpha N E > Muroidea N E > Muridae N E > Murinae N E > Mus [genus] N E > Mus [subgenus] N E > Mus musculus N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

Sequence

Peptide

MPLARLPGWL CVVACGLLLL LQHVHGQDSA SPIRNTHRGQ VRGSFVHVKD TKSGVHAFLG IPFAKPPVGL LRFAPPEDPE PWSGVRDGTS QPAMCLQPDI MNLEDAKEMN LILPPISMSE DCLYLNIYTP THAQEGSNLP VMVWIHGGGL VVGSASMNDV SKLAATEEIV IVAIQYRLGV LGFFSTGDQH ARGNWGYLDQ VAALRWVQKN IAYFGGNRDR VTIFGVSAGG TSVSSHILSP MSKGLFHGAI MQSGVALLPD LISDTSEVVY KTVANLSGCE ATDSEALIHC LRAKSKQEIL AINQVFKMIP AVVDGEFLPK HPQELLTSMD FHPVPSIIGV NTDECGWGVP MFMGLDHIIK NITRETLPAV LKNTAARMML PPECSHLLVE EYMGDTEDPE TLQAQFREML GDFMFVIPAL QVAHFQRSQA PVYFYEFQHL SSFIKHVRPS HVKADHGDDV AFVFGSYLWD MNLDLTEEEE LLKRMMMKYW ANFARNGNPN SEGLPSWPVL DHDEQYLQLD TQPAVGRALK ARRLQFWTKT LPQKIQELKG SQDKHAEL

References (5)

Title : Carboxylesterase 2a deletion provokes hepatic steatosis and insulin resistance in mice involving impaired diacylglycerol and lysophosphatidylcholine catabolism - Chalhoub_2023_Mol.Metab__101725
Author(s) : Chalhoub G , Jamnik A , Pajed L , Kolleritsch S , Hois V , Bagaric A , Prem D , Tilp A , Kolb D , Wolinski H , Taschler U , Zullig T , Rechberger GN , Fuchs C , Trauner M , Schoiswohl G , Haemmerle G
Ref : Mol Metab , :101725 , 2023
Abstract :
PubMedSearch : Chalhoub_2023_Mol.Metab__101725
PubMedID: 37059417
Gene_locus related to this paper: mouse-Ces2a

Title : Carboxylesterase 2 proteins are efficient diglyceride and monoglyceride lipases possibly implicated in metabolic disease - Chalhoub_2021_J.Lipid.Res__100075
Author(s) : Chalhoub G , Kolleritsch S , Maresch LK , Taschler U , Pajed L , Tilp A , Natmessnig H , Rosina P , Kien B , Radner FPW , Schicho R , Oberer M , Schoiswohl G , Haemmerle G
Ref : J Lipid Res , :100075 , 2021
Abstract :
PubMedSearch : Chalhoub_2021_J.Lipid.Res__100075
PubMedID: 33872605
Gene_locus related to this paper: human-CES2 , mouse-Ces2a , mouse-Ces2b , mouse-Ces2c

Title : A tissue-specific atlas of mouse protein phosphorylation and expression - Huttlin_2010_Cell_143_1174
Author(s) : Huttlin EL , Jedrychowski MP , Elias JE , Goswami T , Rad R , Beausoleil SA , Villen J , Haas W , Sowa ME , Gygi SP
Ref : Cell , 143 :1174 , 2010
Abstract :
PubMedSearch : Huttlin_2010_Cell_143_1174
PubMedID: 21183079
Gene_locus related to this paper: mouse-abd12 , mouse-Ces2a , mouse-CMBL , mouse-ndr1 , mouse-ndr2 , mouse-ndr4 , mouse-f172a

Title : Lineage-specific biology revealed by a finished genome assembly of the mouse - Church_2009_PLoS.Biol_7_e1000112
Author(s) : Church DM , Goodstadt L , Hillier LW , Zody MC , Goldstein S , She X , Bult CJ , Agarwala R , Cherry JL , DiCuccio M , Hlavina W , Kapustin Y , Meric P , Maglott D , Birtle Z , Marques AC , Graves T , Zhou S , Teague B , Potamousis K , Churas C , Place M , Herschleb J , Runnheim R , Forrest D , Amos-Landgraf J , Schwartz DC , Cheng Z , Lindblad-Toh K , Eichler EE , Ponting CP
Ref : PLoS Biol , 7 :e1000112 , 2009
Abstract :
PubMedSearch : Church_2009_PLoS.Biol_7_e1000112
PubMedID: 19468303
Gene_locus related to this paper: mouse-1neur , mouse-2neur , mouse-abd12 , mouse-abhd3 , mouse-abhd5 , mouse-acnt1 , mouse-adcl3 , mouse-bphl , mouse-c1ib , mouse-cauxin , mouse-Ces1a , mouse-Ces1b , mouse-Ces1c , mouse-Ces1e , mouse-Ces1h , mouse-Ces2a , mouse-Ces2c , mouse-Ces2f , mouse-Ces2g , mouse-Ces2h , mouse-Ces3b , mouse-Ces4a , mouse-CMBL , mouse-Dorz1 , mouse-DPP6 , mouse-dpp10 , mouse-ephx4 , mouse-g3uzn6 , mouse-KFA , mouse-LIPN , mouse-Lipo2 , mouse-Lipo4 , mouse-MEST , mouse-ndr1 , mouse-ndr4 , mouse-notum , mouse-q3uuq7 , mouse-Q8C1A9 , mouse-Q9DAI6 , mouse-SERHL , mouse-Tex30 , mouse-thyro , mouse-tmco4 , mouse-b1avu7 , mouse-b2rwd2 , mouse-j3qpi0 , mouse-w4vsp6 , mouse-f172a , mouse-f6yqt7

Title : Identification, expression, and purification of a pyrethroid-hydrolyzing carboxylesterase from mouse liver microsomes - Stok_2004_J.Biol.Chem_279_29863
Author(s) : Stok JE , Huang H , Jones PD , Wheelock CE , Morisseau C , Hammock BD
Ref : Journal of Biological Chemistry , 279 :29863 , 2004
Abstract :
PubMedSearch : Stok_2004_J.Biol.Chem_279_29863
PubMedID: 15123619
Gene_locus related to this paper: mouse-Ces2a , mouse-Ces2e