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| Title : Effects of the novel alpha7 nicotinic acetylcholine receptor agonist ABT-107 on sensory gating in DBA\/2 mice: pharmacodynamic characterization - Radek_2012_J.Pharmacol.Exp.Ther_343_736 |
| Author(s) : Radek RJ , Robb HM , Stevens KE , Gopalakrishnan M , Bitner RS |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 343 :736 , 2012 |
| Abstract : Radek_2012_J.Pharmacol.Exp.Ther_343_736 |
| ESTHER : Radek_2012_J.Pharmacol.Exp.Ther_343_736 |
| PubMedSearch : Radek_2012_J.Pharmacol.Exp.Ther_343_736 |
| PubMedID: 22988063 |
| Title : Poster: Positive allosteric modulation of alpha4\/beta2 nicotinic receptors potentiates some CNS effects of the alpha4\/beta2 agonist, ABT-594 - |
| Author(s) : Franklin SR , Mohler EG , Komater VA , Robb H , Radek RJ , Rustay NR , Brown JW , Gopalakrishnan M , Decker MW , Rueter LE |
| Ref : Biochemical Pharmacology , 78 :921 , 2009 |
| PubMedID: |
| Title : Discovery of 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a novel positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor - Faghih_2009_J.Med.Chem_52_3377 |
| Author(s) : Faghih R , Gopalakrishnan SM , Gronlien JH , Malysz J , Briggs CA , Wetterstrand C , Ween H , Curtis MP , Sarris KA , Gfesser GA , El-Kouhen R , Robb HM , Radek RJ , Marsh KC , Bunnelle WH , Gopalakrishnan M |
| Ref : Journal of Medicinal Chemistry , 52 :3377 , 2009 |
| Abstract : Faghih_2009_J.Med.Chem_52_3377 |
| ESTHER : Faghih_2009_J.Med.Chem_52_3377 |
| PubMedSearch : Faghih_2009_J.Med.Chem_52_3377 |
| PubMedID: 19419141 |
| Title : Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties - Tietje_2008_CNS.Neurosci.Ther_14_65 |
| Author(s) : Tietje KR , Anderson DJ , Bitner RS , Blomme EA , Brackemeyer PJ , Briggs CA , Browman KE , Bury D , Curzon P , Drescher KU , Frost JM , Fryer RM , Fox GB , Gronlien JH , Hakerud M , Gubbins EJ , Halm S , Harris R , Helfrich RJ , Kohlhaas KL , Law D , Malysz J , Marsh KC , Martin RL , Meyer MD , Molesky AL , Nikkel AL , Otte S , Pan L , Puttfarcken PS , Radek RJ , Robb HM , Spies E , Thorin-Hagene K , Waring JF , Ween H , Xu H , Gopalakrishnan M , Bunnelle WH |
| Ref : CNS Neurosci Ther , 14 :65 , 2008 |
| Abstract : Tietje_2008_CNS.Neurosci.Ther_14_65 |
| ESTHER : Tietje_2008_CNS.Neurosci.Ther_14_65 |
| PubMedSearch : Tietje_2008_CNS.Neurosci.Ther_14_65 |
| PubMedID: 18482100 |
| Title : Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1\/2 and CREB phosphorylation pathways - Bitner_2007_J.Neurosci_27_10578 |
| Author(s) : Bitner RS , Bunnelle WH , Anderson DJ , Briggs CA , Buccafusco JJ , Curzon P , Decker MW , Frost JM , Gronlien JH , Gubbins E , Li J , Malysz J , Markosyan S , Marsh K , Meyer MD , Nikkel AL , Radek RJ , Robb HM , Timmermann DB , Sullivan JP , Gopalakrishnan M |
| Ref : Journal of Neuroscience , 27 :10578 , 2007 |
| Abstract : Bitner_2007_J.Neurosci_27_10578 |
| ESTHER : Bitner_2007_J.Neurosci_27_10578 |
| PubMedSearch : Bitner_2007_J.Neurosci_27_10578 |
| PubMedID: 17898229 |
| Title : Alpha4beta2 nicotinic receptor stimulation contributes to the effects of nicotine in the DBA\/2 mouse model of sensory gating - Radek_2006_Psychopharmacology.(Berl)_187_47 |
| Author(s) : Radek RJ , Miner HM , Bratcher NA , Decker MW , Gopalakrishnan M , Bitner RS |
| Ref : Psychopharmacology (Berl) , 187 :47 , 2006 |
| Abstract : Radek_2006_Psychopharmacology.(Berl)_187_47 |
| ESTHER : Radek_2006_Psychopharmacology.(Berl)_187_47 |
| PubMedSearch : Radek_2006_Psychopharmacology.(Berl)_187_47 |
| PubMedID: 16767415 |
| Title : ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective antinociceptive agent acting via neuronal nicotinic acetylcholine receptors: II. In vivo characterization - Bannon_1998_J.Pharmacol.Exp.Ther_285_787 |
| Author(s) : Bannon AW , Decker MW , Curzon P , Buckley MJ , Kim DJ , Radek RJ , Lynch JK , Wasicak JT , Lin NH , Arnold WH , Holladay MW , Williams M , Arneric SP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 285 :787 , 1998 |
| Abstract : Bannon_1998_J.Pharmacol.Exp.Ther_285_787 |
| ESTHER : Bannon_1998_J.Pharmacol.Exp.Ther_285_787 |
| PubMedSearch : Bannon_1998_J.Pharmacol.Exp.Ther_285_787 |
| PubMedID: 9580627 |
| Title : Potential treatment of Alzheimer disease using cholinergic channel activators (ChCAs) with cognitive enhancement, anxiolytic-like, and cytoprotective properties - Arneric_1995_Alzheimer.Dis.Assoc.Disord_9 Suppl 2_50 |
| Author(s) : Arneric SP , Sullivan JP , Decker MW , Brioni JD , Bannon AW , Briggs CA , Donnelly-Roberts D , Radek RJ , Marsh KC , Kyncl J , Williams M , Buccafusco JJ |
| Ref : Alzheimer Disease & Associated Disorders , 9 Suppl 2 :50 , 1995 |
| Abstract : Arneric_1995_Alzheimer.Dis.Assoc.Disord_9 Suppl 2_50 |
| ESTHER : Arneric_1995_Alzheimer.Dis.Assoc.Disord_9 Suppl 2_50 |
| PubMedSearch : Arneric_1995_Alzheimer.Dis.Assoc.Disord_9 Suppl 2_50 |
| PubMedID: 8534424 |