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Author Report for: Tsurkan L

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Chatonnet Arnaud Bourne Yves Masson Patrick Lenfant Nicolas Marchot Pascale Paul Hrabovska Anna Vidal-Moreno Cecilio J Krejci Eric Nachon Florian Soreq Hermona Sussman Joel L Lockridge Oksana Tsim KW Rosenberry Terrone L Doctor Bhupendra P Kovarik Zrinka
The 11th International Meeting on Cholinesterases

    Title: Carboxylesterases: General detoxifying enzymes
    Hatfield MJ, Umans RA, Hyatt JL, Edwards CC, Wierdl M, Tsurkan L, Taylor MR, Potter PM
    Ref: Chemico-Biological Interactions, 259:327, 2016 : PubMed


    Title: Tumour-selective targeting of drug metabolizing enzymes to treat metastatic cancer
    Wierdl M, Tsurkan L, Hatfield MJ, Potter PM
    Ref: British Journal of Pharmacology, 173:2811, 2016 : PubMed


    Title: Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11
    Hatfield MJ, Tsurkan L, Garrett M, Shaver TM, Hyatt JL, Edwards CC, Hicks LD, Potter PM
    Ref: Biochemical Pharmacology, 81:24, 2011 : PubMed


    Title: Nerve agent hydrolysis activity designed into a human drug metabolism enzyme
    Hemmert AC, Otto TC, Chica RA, Wierdl M, Edwards JS, Lewis SM, Edwards CC, Tsurkan L, Cadieux CL and Redinbo MR <5 more author(s)>
    Ref: PLoS ONE, 6:e17441, 2011 : PubMed


    Title: Requirements for mammalian carboxylesterase inhibition by substituted ethane-1,2-diones
    Parkinson EI, Hatfield MJ, Tsurkan L, Hyatt JL, Edwards CC, Hicks LD, Yan B, Potter PM
    Ref: Bioorganic & Medicinal Chemistry, 19:4635, 2011 : PubMed


    Title: Improved, selective, human intestinal carboxylesterase inhibitors designed to modulate 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (Irinotecan; CPT-11) toxicity
    Hicks LD, Hyatt JL, Stoddard S, Tsurkan L, Edwards CC, Wadkins RM, Potter PM
    Ref: Journal of Medicinal Chemistry, 52:3742, 2009 : PubMed


    Title: An improved human carboxylesterase for enzyme/prodrug therapy with CPT-11
    Wierdl M, Tsurkan L, Hyatt JL, Edwards CC, Hatfield MJ, Morton CL, Houghton PJ, Danks MK, Redinbo MR, Potter PM
    Ref: Cancer Gene Therapy, 15:183, 2008 : PubMed


    Title: Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma
    Danks MK, Yoon KJ, Bush RA, Remack JS, Wierdl M, Tsurkan L, Kim SU, Garcia E, Metz MZ and Aboody KS <2 more author(s)>
    Ref: Cancer Research, 67:22, 2007 : PubMed


    Title: Analysis of the inhibition of mammalian carboxylesterases by novel fluorobenzoins and fluorobenzils
    Hicks LD, Hyatt JL, Moak T, Edwards CC, Tsurkan L, Wierdl M, Ferreira AM, Wadkins RM, Potter PM
    Ref: Bioorganic & Medicinal Chemistry, 15:3801, 2007 : PubMed


    Title: Planarity and constraint of the carbonyl groups in 1,2-diones are determinants for selective inhibition of human carboxylesterase 1
    Hyatt JL, Wadkins RM, Tsurkan L, Hicks LD, Hatfield MJ, Edwards CC, Ross CR, 2nd, Cantalupo SA, Crundwell G and Potter PM <2 more author(s)>
    Ref: Journal of Medicinal Chemistry, 50:5727, 2007 : PubMed


    Title: Selective inhibition of carboxylesterases by isatins, indole-2,3-diones
    Hyatt JL, Moak T, Hatfield MJ, Tsurkan L, Edwards CC, Wierdl M, Danks MK, Wadkins RM, Potter PM
    Ref: Journal of Medicinal Chemistry, 50:1876, 2007 : PubMed


    Title: Analysis of mammalian carboxylesterase inhibition by trifluoromethylketone-containing compounds
    Wadkins RM, Hyatt JL, Edwards CC, Tsurkan L, Redinbo MR, Wheelock CE, Jones PD, Hammock BD, Potter PM
    Ref: Molecular Pharmacology, 71:713, 2007 : PubMed


    Title: Intracellular inhibition of carboxylesterases by benzil: modulation of CPT-11 cytotoxicity
    Hyatt JL, Tsurkan L, Wierdl M, Edwards CC, Danks MK, Potter PM
    Ref: Mol Cancer Ther, 5:2281, 2006 : PubMed


    Title: Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil
    Fleming CD, Bencharit S, Edwards CC, Hyatt JL, Tsurkan L, Bai F, Fraga C, Morton CL, Howard-Williams EL and Redinbo MR <1 more author(s)>
    Ref: Journal of Molecular Biology, 352:165, 2005 : PubMed


    Title: Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11
    Hyatt JL, Tsurkan L, Morton CL, Yoon KJ, Harel M, Brumshtein B, Silman I, Sussman JL, Wadkins RM, Potter PM
    Ref: Chemico-Biological Interactions, 157-158:247, 2005 : PubMed


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
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