Family: Chlorophyllase_Plant

Block: L

Parent Family: No family


This family consists of several plant specific Chlorophyllase proteins (EC: Chlorophyllase (Chlase) is the first enzyme involved in chlorophylle (Chl) degradation and catalyses the hydrolysis of ester bond to yield chlorophyllide and phytol The family includes both plant bacteria and Amphioxus members. However Chlorophyllase is not localized to plastids, and double knockout mutant plants still are able to degrade chlorophyll during leaf senescence. So pheophytinase is a new pathway. Chlorophyllase could be more important in fruit rippening. Some bacterial enzyme are close to plant chlorophyllases but are now separated in another family Chlorophyllase. (Few sponge or marine invertebrates protein included). A structure-function analysis of chlorophyllase reveals a mechanism for activity regulation dependent on disulfide bonds(Jo et al.)


Interpro : IPR017395 Chlorophyllase\/cutinase , IPR048264 Chlorophyllase

PIRSF : PIRSF038128 (Chlorophyllase_chloroplast)

Pdoc : No Pdoc

Pfam : PF07224 Chlorophyllase

Prints : No Print

EC Number :


Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

Structures (1)

Genes Proteins in Chlorophyllase_Plant family (177)

Fragments of genes in Chlorophyllase_Plant family (43)

Structures in Chlorophyllase_Plant family (1)

Substrates in Chlorophyllase_Plant family (3)

No Inhibitor

References (5)

Title : A structure-function analysis of chlorophyllase reveals a mechanism for activity regulation dependent on disulfide bonds - Jo_2023_J.Biol.Chem__102958
Author(s) : Jo M , Knapp M , Boggs DG , Brimberry M , Donnan PH , Bridwell-Rabb J
Ref : Journal of Biological Chemistry , :102958 , 2023
PubMedID: 36731794
Gene_locus related to this paper: wheat-w5h2c8

Title : Chlorophyll degradation during senescence - Hortensteiner_2006_Annu.Rev.Plant.Biol_57_55
Author(s) : Hortensteiner S
Ref : Annu Rev Plant Biol , 57 :55 , 2006
PubMedID: 16669755

Title : Mechanistic analysis of wheat chlorophyllase - Arkus_2005_Arch.Biochem.Biophys_438_146
Author(s) : Arkus KA , Cahoon EB , Jez JM
Ref : Archives of Biochemistry & Biophysics , 438 :146 , 2005
PubMedID: 15913540
Gene_locus related to this paper: wheat-w5h2c8

Title : Chlorophyllase as a serine hydrolase: identification of a putative catalytic triad - Tsuchiya_2003_Plant.Cell.Physiol_44_96
Author(s) : Tsuchiya T , Suzuki T , Yamada T , Shimada H , Masuda T , Ohta H , Takamiya K
Ref : Plant Cell Physiol , 44 :96 , 2003
PubMedID: 12552153
Gene_locus related to this paper: cheal-CACLH

Title : Cloning of chlorophyllase, the key enzyme in chlorophyll degradation: finding of a lipase motif and the induction by methyl jasmonate - Tsuchiya_1999_Proc.Natl.Acad.Sci.U.S.A_96_15362
Author(s) : Tsuchiya T , Ohta H , Okawa K , Iwamatsu A , Shimada H , Masuda T , Takamiya K
Ref : Proc Natl Acad Sci U S A , 96 :15362 , 1999
PubMedID: 10611389
Gene_locus related to this paper: arath-clh1 , arath-clh2 , cheal-CACLH