Mus musculus Mouse and Mus musculus molossinus (Japanese house mouse) Mesoderm-specific transcript protein
Mesoderm-specific transcript (Mest) predominantly expressed in mesoderm and its derivatives is also an imprinted gene whose expression is dependent on parental origin and is designated Peg1 (paternally expressed gene-1). Identification and characterization of an imprinted antisense RNART (MESTIT1) in the human MEST locus on chromosome 7q32 PubMed 12095916. Q4L141_MUSMM Mus musculus molossinus (Japanese house mouse). Mest is involved in the modulation of adipose tissue expansion. Mest is also highly expressed in the developing and adult brain
Family : MEST-like
Block : X
Position in NCBI Life Tree : Mus musculus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Glires N E > Rodentia N E > Myomorpha N E > Muroidea N E > Muridae N E > Murinae N E > Mus [genus] N E > Mus [subgenus] N E > Mus musculus N EMVRRDRLRRM REWWVQVGLL AVPLLAAYLH IPPPQLSPAL HSWKTSGKFF TYKGLRIFYQ DSVGVVGSPE IVVLLHGFPT SSYDWYKIWE GLTLRFHRVI ALDFLGFGFS DKPRPHQYSI FEQASIVESL LRHLGLQNRR INLLSHDYGD IVAQELLYRY KQNRSGRLTI KSLCLSNGGI FPETHRPLLL QKLLKDGGVL SPILTRLMNF FVFSRGLTPV FGPYTRPTES ELWDMWAVIR NNDGNLVIDS LLQYINQRKK FRRRWVGALA SVSIPIHFIY GPLDPINPYP EFLELYRKTL PRSTVSILDD HISHYPQLED PMGFLNAYMG FINSF
| Title : Increased spontaneous physical activity in female MEST-deficient mice protects against diet-induced obesity - Anunciado-Koza_2025_Front.Endocrinol_16_ |
| Author(s) : Anunciado-Koza RVP , Martinez ME , DeMambro V , Hernandez A , Koza RA |
| Ref : Frontiers in Endocrinology , 16 : , 2025 |
| Abstract : |
| PubMedSearch : Anunciado-Koza_2025_Front.Endocrinol_16_ |
| PubMedID: |
| Gene_locus related to this paper: human-MEST , mouse-MEST |
| Title : Social and maternal behavior in mesoderm specific transcript (Mest)-deficient mice - Anunciado-Koza_2022_PLoS.One_17_e0271913 |
| Author(s) : Anunciado-Koza RP , Stohn JP , Hernandez A , Koza RA |
| Ref : PLoS ONE , 17 :e0271913 , 2022 |
| Abstract : |
| PubMedSearch : Anunciado-Koza_2022_PLoS.One_17_e0271913 |
| PubMedID: 35867696 |
| Gene_locus related to this paper: mouse-MEST |
| Title : Mesoderm-specific transcript localization in the ER and ER-lipid droplet interface supports a role in adipocyte hypertrophy - Prudovsky_2018_J.Cell.Biochem_119_2636 |
| Author(s) : Prudovsky I , Anunciado-Koza RP , Jacobs CG , Kacer D , Siviski ME , Koza RA |
| Ref : Journal of Cellular Biochemistry , 119 :2636 , 2018 |
| Abstract : |
| PubMedSearch : Prudovsky_2018_J.Cell.Biochem_119_2636 |
| PubMedID: 29058774 |
| Gene_locus related to this paper: human-MEST , mouse-MEST |
| Title : Diet-induced adipose tissue expansion is mitigated in mice with a targeted inactivation of mesoderm specific transcript (Mest) - Anunciado-Koza_2017_PLoS.One_12_e0179879 |
| Author(s) : Anunciado-Koza RP , Manuel J , Mynatt RL , Zhang J , Kozak LP , Koza RA |
| Ref : PLoS ONE , 12 :e0179879 , 2017 |
| Abstract : |
| PubMedSearch : Anunciado-Koza_2017_PLoS.One_12_e0179879 |
| PubMedID: 28640866 |
| Gene_locus related to this paper: mouse-MEST |
| Title : Defective neuronal migration and inhibition of bipolar to multipolar transition of migrating neural cells by Mesoderm-Specific Transcript, Mest, in the developing mouse neocortex - Ji_2017_Neurosci_355_126 |
| Author(s) : Ji L , Bishayee K , Sadra A , Choi S , Choi W , Moon S , Jho EH , Huh SO |
| Ref : Neuroscience , 355 :126 , 2017 |
| Abstract : |
| PubMedSearch : Ji_2017_Neurosci_355_126 |
| PubMedID: 28501506 |
| Gene_locus related to this paper: human-MEST , mouse-MEST |
| Title : Adipose tissue Mest and Sfrp5 are concomitant with variations of adiposity among inbred mouse strains fed a non-obesogenic diet - Anunciado-Koza_2016_Biochimie_124_134 |
| Author(s) : Anunciado-Koza RP , Higgins DC , Koza RA |
| Ref : Biochimie , 124 :134 , 2016 |
| Abstract : |
| PubMedSearch : Anunciado-Koza_2016_Biochimie_124_134 |
| PubMedID: 26005096 |
| Gene_locus related to this paper: human-MEST , mouse-MEST |
| Title : Mest\/Peg1 Is Essential for the Development and Maintenance of a SNc Neuronal Subset - Mesman_2016_Front.Mol.Neurosci_9_166 |
| Author(s) : Mesman S , van Hooft JA , Smidt MP |
| Ref : Front Mol Neurosci , 9 :166 , 2016 |
| Abstract : |
| PubMedSearch : Mesman_2016_Front.Mol.Neurosci_9_166 |
| PubMedID: 28133444 |
| Gene_locus related to this paper: human-MEST , mouse-MEST |
| Title : Identification of Mest\/Peg1 gene expression as a predictive biomarker of adipose tissue expansion sensitive to dietary anti-obesity interventions - Voigt_2015_Genes.Nutr_10_477 |
| Author(s) : Voigt A , Ribot J , Sabater AG , Palou A , Bonet ML , Klaus S |
| Ref : Genes Nutr , 10 :477 , 2015 |
| Abstract : |
| PubMedSearch : Voigt_2015_Genes.Nutr_10_477 |
| PubMedID: 26143179 |
| Gene_locus related to this paper: human-MEST , mouse-MEST |
| Title : Inter-individual variation of dietary fat-induced mesoderm specific transcript in adipose tissue within inbred mice is not caused by altered promoter methylation - Koza_2009_Epigenetics_4_512 |
| Author(s) : Koza RA , Rogers P , Kozak LP |
| Ref : Epigenetics , 4 :512 , 2009 |
| Abstract : |
| PubMedSearch : Koza_2009_Epigenetics_4_512 |
| PubMedID: 19875931 |
| Gene_locus related to this paper: human-MEST , mouse-MEST |
| Title : Mesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balance - Nikonova_2008_FASEB.J_22_3925 |
| Author(s) : Nikonova L , Koza RA , Mendoza T , Chao PM , Curley JP , Kozak LP |
| Ref : FASEB Journal , 22 :3925 , 2008 |
| Abstract : |
| PubMedSearch : Nikonova_2008_FASEB.J_22_3925 |
| PubMedID: 18644838 |
| Gene_locus related to this paper: human-MEST , mouse-MEST |
| Title : Peg1\/Mest in obese adipose tissue is expressed from the paternal allele in an isoform-specific manner - Kamei_2007_FEBS.Lett_581_91 |
| Author(s) : Kamei Y , Suganami T , Kohda T , Ishino F , Yasuda K , Miura S , Ezaki O , Ogawa Y |
| Ref : FEBS Letters , 581 :91 , 2007 |
| Abstract : |
| PubMedSearch : Kamei_2007_FEBS.Lett_581_91 |
| PubMedID: 17182038 |
| Gene_locus related to this paper: human-MEST , mouse-MEST |
| Title : Increased plasticity of genomic imprinting of Dlk1 in brain is due to genetic and epigenetic factors - Croteau_2005_Mamm.Genome_16_127 |
| Author(s) : Croteau S , Roquis D , Charron MC , Frappier D , Yavin D , Loredo-Osti JC , Hudson TJ , Naumova AK |
| Ref : Mamm Genome , 16 :127 , 2005 |
| Abstract : |
| PubMedSearch : Croteau_2005_Mamm.Genome_16_127 |
| PubMedID: 15859358 |
| Gene_locus related to this paper: mouse-MEST |
| Title : Mest\/Peg1 imprinted gene enlarges adipocytes and is a marker of adipocyte size - Takahashi_2005_Am.J.Physiol.Endocrinol.Metab_288_E117 |
| Author(s) : Takahashi M , Kamei Y , Ezaki O |
| Ref : American Journal of Physiology Endocrinol Metab , 288 :E117 , 2005 |
| Abstract : |
| PubMedSearch : Takahashi_2005_Am.J.Physiol.Endocrinol.Metab_288_E117 |
| PubMedID: 15353408 |
| Gene_locus related to this paper: human-MEST , mouse-MEST |
| Title : Identification and characterization of an imprinted antisense RNA (MESTIT1) in the human MEST locus on chromosome 7q32 - Nakabayashi_2002_Hum.Mol.Genet_11_1743 |
| Author(s) : Nakabayashi K , Bentley L , Hitchins MP , Mitsuya K , Meguro M , Minagawa S , Bamforth JS , Stanier P , Preece M , Weksberg R , Oshimura M , Moore GE , Scherer SW |
| Ref : Hum Mol Genet , 11 :1743 , 2002 |
| Abstract : |
| PubMedSearch : Nakabayashi_2002_Hum.Mol.Genet_11_1743 |
| PubMedID: 12095916 |
| Gene_locus related to this paper: mouse-MEST |
| Title : Abnormal maternal behaviour and growth retardation associated with loss of the imprinted gene Mest - Lefebvre_1998_Nat.Genet_20_163 |
| Author(s) : Lefebvre L , Viville S , Barton SC , Ishino F , Keverne EB , Surani MA |
| Ref : Nat Genet , 20 :163 , 1998 |
| Abstract : |
| PubMedSearch : Lefebvre_1998_Nat.Genet_20_163 |
| PubMedID: 9771709 |
| Gene_locus related to this paper: human-MEST , mouse-MEST |
| Title : Genomic structure and parent-of-origin-specific methylation of Peg1 - Lefebvre_1997_Hum.Mol.Genet_6_1907 |
| Author(s) : Lefebvre L , Viville S , Barton SC , Ishino F , Surani MA |
| Ref : Hum Mol Genet , 6 :1907 , 1997 |
| Abstract : |
| PubMedSearch : Lefebvre_1997_Hum.Mol.Genet_6_1907 |
| PubMedID: 9302270 |
| Gene_locus related to this paper: human-MEST , mouse-MEST |
| Title : Peg1\/Mest imprinted gene on chromosome 6 identified by cDNA subtraction hybridization - Kaneko-Ishino_1995_Nat.Genet_11_52 |
| Author(s) : Kaneko-Ishino T , Kuroiwa Y , Miyoshi N , Kohda T , Suzuki R , Yokoyama M , Viville S , Barton SC , Ishino F , Surani MA |
| Ref : Nat Genet , 11 :52 , 1995 |
| Abstract : |
| PubMedSearch : Kaneko-Ishino_1995_Nat.Genet_11_52 |
| PubMedID: 7550314 |
| Gene_locus related to this paper: mouse-MEST |
| Title : A novel mesoderm-specific cDNA isolated from a mouse embryonal carcinoma cell line - |
| Author(s) : Sado T , Nakajima N , Tada M , Takagi N |
| Ref : Dev Growth Differ , 35 :551 , 1993 |
| PubMedID: |
| Gene_locus related to this paper: human-MEST , mouse-MEST |