Gene_Locus Report

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Gene_locus Report for: aspa1-acrc

Aspergillus aculeatus (strain ATCC 16872 / CBS 172.66 / WB 5094). Acurin A biosynthesis cluster protein C

Relationship
Family|Duf_1100-S
Block| X
Position in NCBI Life Tree|Aspergillus aculeatus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Fungi: N E > Dikarya: N E > Ascomycota: N E > saccharomyceta: N E > Pezizomycotina: N E > leotiomyceta: N E > Eurotiomycetes: N E > Eurotiomycetidae: N E > Eurotiales: N E > Aspergillaceae: N E > Aspergillus: N E > Aspergillus subgen. Circumdati: N E > Aspergillus aculeatus: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
1 Genbank : KV878980
1 UniProt : P9WEZ7
2 UniProt : P9WEZ7, A0A1L9WR54
2 Interpro : P9WEZ7, A0A1L9WR54
2 Pfam : P9WEZ7, A0A1L9WR54
2 PIRSF : P9WEZ7, A0A1L9WR54
2 SUPERFAM : P9WEZ7, A0A1L9WR54
Sequence
Graphical view for this peptide sequence: aspa1-acrc
Colored MSA for Duf_1100-S (raw)
MFKFYPSDFFHFEFLRVLASAPAGGAETGECLAVLPQVPDGDAEAWYRAW
TAQAQQARGLGDEALVSGDTVAASGAYLRASNYFRASEFFLHTRPDDPRL
LAAMENSVAVFDKGVDLLDTCTVVRVEIPYEEEKGAARLPGRLYLPRSGA
AQTGQGQSEDKLPLLIMTGGFDSTQEELYFFGPAAALPRGYAVLTFEGPG
QGICLRRDGLRLRPDWEHVTTKVLDVVESQLAKDYPIDLERVAVVGASLG
GYFALRAAADPRVRACVSCDACYDLFDVTRSRMPGWFINGWLSRRLSDGF
FNWVVNKLAGWSFQLRWEFGHSMWVYGVESPAEVMRCMQQYHARGYLQKV
KCSTFVTGAADTFYFTPKQNTEPIFEALGHVPLQKKRLWIGKGVEGGGLQ
AKIGAWAVFHQKMFVWLDEQFEIKRGTI
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MFKFYPSDFFHFEFLRVLASAPAGGAETGECLAVLPQVPDGDAEAWYRAW
TAQAQQARGLGDEALVSGDTVAASGAYLRASNYFRASEFFLHTRPDDPRL
LAAMENSVAVFDKGVDLLDTCTVVRVEIPYEEEKGAARLPGRLYLPRSGA
AQTGQGQSEDKLPLLIMTGGFDSTQEELYFFGPAAALPRGYAVLTFEGPG
QGICLRRDGLRLRPDWEHVTTKVLDVVESQLAKDYPIDLERVAVVGASLG
GYFALRAAADPRVRACVSCDACYDLFDVTRSRMPGWFINGWLSRRLSDGF
FNWVVNKLAGWSFQLRWEFGHSMWVYGVESPAEVMRCMQQYHARGYLQKV
KCSTFVTGAADTFYFTPKQNTEPIFEALGHVPLQKKRLWIGKGVEGGGLQ
AKIGAWAVFHQKMFVWLDEQFEIKRGTI


References
    Title: Acurin A, a novel hybrid compound, biosynthesized by individually translated PKS- and NRPS-encoding genes in Aspergillus aculeatus
    Wolff PB, Nielsen ML, Slot JC, Andersen LN, Petersen LM, Isbrandt T, Holm DK, Mortensen UH, Nodvig CS and Hoof JB <1 more author(s)>
    Ref: Fungal Genet Biol, 139:103378, 2020 : PubMed

            

    Title: Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus
    de Vries RP, Riley R, Wiebenga A, Aguilar-Osorio G, Amillis S, Uchima CA, Anderluh G, Asadollahi M, Askin M and Grigoriev IV <107 more author(s)>
    Ref: Genome Biol, 18:28, 2017 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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