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Derivative of Propidium

General

Propidium is a fluorescent intercalating agent that can be used to stain cells and nucleic acids. Also aninhibitor of cholinesterases. Has red fluorescence at 488 nm. Has the following spectral properties: extinction coefficient: 5,900 M -1 cm -1 (493 nm); 55,700 M -1 cm -1 (287 nm) 13,800 M -1 cm -1 (252.5 nm); excitation maximum: 536 nm; emission maximum: 617 nm. Used as building blocks of Multi-target drug ligand MTDL
Inhibitor Main targeted enzyme families Type Structure
CHEMBL361165 ACHE Phenanthridinium Phenanthrene Derivative of Propidium Alkyl linked bis-ligand anti-Abeta-aggregation Multitarget
CHEMBL179455 ACHE Acridine Phenanthridinium Phenanthrene Derivative of Tacrine Derivative of Propidium Alkyl linked bis-ligand anti-Abeta-aggregation Multitarget
Pa5 ACHE Phenanthridinium Derivative of Propidium Alkyne
Pa6 ACHE Phenanthridinium Derivative of Propidium Alkyne
Tz2Pa6-syn1 ACHE Acridine Phenanthridinium Derivative of Tacrine Derivative of Propidium Alkyl linked bis-ligand Triazol
Tz2Pa5-syn1 ACHE Acridine Phenanthridinium Derivative of Propidium Derivative of Tacrine Alkyl linked bis-ligand Triazol
TZ2PIQA5 ACHE Acridine Quinoline Derivative of Propidium Derivative of Tacrine Alkyl linked bis-ligand Triazol
Tz2Pa6-anti1 ACHE Acridine Phenanthridinium Derivative of Tacrine Derivative of Propidium Alkyl linked bis-ligand Triazol
Tz2Pa5-anti1 ACHE Acridine Phenanthridinium Derivative of Propidium Derivative of Tacrine Alkyl linked bis-ligand Triazol
Decidium ACHE Bisquaternary Trimethylammonium Ammonium Phenanthridinium Derivative of Propidium
Propidium ACHE BCHE Phenanthridinium Fluorescent Probe Derivative of Propidium