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Derivative of VX

General

Derivatives of the organophosphate nerve agent (V-series VX) designed as building blocks of less toxic compounds for biochemical studies, and for understanding toxicity or mechanism of reactivation of cholinesterases inhibited by OPs
Inhibitor Main targeted enzyme families Type Structure
EA-2192 ACHE Chemical Warfare Agent Organophosphate Nerve Agent V-series Derivative of VX Sulfur Compound
VXS BCHE ACHE PET probe Organophosphate Derivative of Paraoxon Derivative of VX pNP
VX-Biotin Carboxypeptidase_S10 ACHE BCHE A85-EsteraseD-FGH ACPH_Peptidase_S9 Carb_B_Chordata Hormone-sensitive_lipase_like LYsophospholipase_carboxylesterase Lipase_3 Monoglyceridelipase_lysophospholip Arylacetamide_deacetylase Thioesterase DPP4N_Peptidase_S9 PC-sterol_acyltransferase ABHD6-Lip PAF-Acetylhydrolase S9N_PREPL_Peptidase_S9 PPase_methylesterase_euk Kynurenine-formamidase Organophosphate ABPP-Probe Imidazole Sulfur Compound Biotin derivative Derivative of VX
NEMP-F ACHE Organophosphate Surrogate OP Nerve Agent V-series Derivative of VX pNP
NEMP ACHE Cholesterol_esterase Organophosphate Surrogate OP Nerve Agent V-series Derivative of VX pNP
TEMP ACHE Organophosphate Surrogate OP Nerve Agent V-series Derivative of VX
VX ACHE BCHE Chemical Warfare Agent Organophosphate Nerve Agent V-series Derivative of VX Sulfur Compound