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Derivative of Sarin

General

Derivatives of the organophosphate nerve agent sarin (GB) designed as building blocks of less toxic compounds for biochemical studies, and for understanding toxicity or mechanism of reactivation of cholinesterases inhibited by OPs
Inhibitor Main targeted enzyme families Type Structure
NCMP ACHE Chemical Warfare Agent Organophosphate Nerve Agent G-series Derivative of Sarin pNP
BIMP ACHE BCHE Derivative of Sarin Organophosphate Surrogate OP Nerve Agent G-series
Cyclosarin ACHE BCHE Carboxypeptidase_S10 Chemical Warfare Agent Organophosphate Nerve Agent G-series Derivative of Sarin
CMP-MeCyC ACHE Organophosphate Flu-OP Nerve Agent G-series Surrogate OP Coumarin Derivative of Sarin Chromen Cyanide
IMP-MeCyC ACHE Organophosphate Flu-OP Nerve Agent G-series Surrogate OP Derivative of Sarin Chromen Coumarin Cyanide
IMP-DDAO ACHE Organophosphate Flu-OP Nerve Agent G-series Surrogate OP Derivative of Tacrine Derivative of Sarin
IMP-pNP ACHE Cholesterol_esterase Organophosphate Surrogate OP Nerve Agent G-series pNP Derivative of Sarin
IMP-pNP-F ACHE Organophosphate Surrogate OP Nerve Agent G-series pNP Derivative of Sarin
PIMP ACHE Organophosphate Surrogate OP Nerve Agent G-series Derivative of Sarin Phthalimido Isoindole Indole
Methylsarin ACHE Chemical Warfare Agent Organophosphate Nerve Agent G-series Derivative of Sarin
Ethylsarin ACHE Chemical Warfare Agent Organophosphate Nerve Agent G-series Derivative of Sarin
n-Propylsarin ACHE BCHE Chemical Warfare Agent Organophosphate Nerve Agent G-series Derivative of Sarin
i-Butylsarin ACHE BCHE Chemical Warfare Agent Organophosphate Nerve Agent G-series Derivative of Sarin
n-Pentylsarin ACHE BCHE Chemical Warfare Agent Organophosphate Nerve Agent G-series Derivative of Sarin
iso-Pentylsarin ACHE BCHE Chemical Warfare Agent Organophosphate Nerve Agent G-series Derivative of Sarin
sec-Pentylsarin ACHE BCHE Chemical Warfare Agent Organophosphate Nerve Agent G-series Derivative of Sarin
neo-Pentylsarin ACHE BCHE Chemical Warfare Agent Organophosphate Nerve Agent G-series Derivative of Sarin
n-Butylsarin ACHE BCHE Chemical Warfare Agent Organophosphate Nerve Agent G-series Derivative of Sarin
Sarin ACHE BCHE PAF-Acetylhydrolase Carboxypeptidase_S10 Chemical Warfare Agent Organophosphate Nerve Agent G-series Derivative of Sarin