Trail F

References (4)

Title : Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses - O'Connell_2012_Nat.Genet_44_1060
Author(s) : O'Connell RJ , Thon MR , Hacquard S , Amyotte SG , Kleemann J , Torres MF , Damm U , Buiate EA , Epstein L , Alkan N , Altmuller J , Alvarado-Balderrama L , Bauser CA , Becker C , Birren BW , Chen Z , Choi J , Crouch JA , Duvick JP , Farman MA , Gan P , Heiman D , Henrissat B , Howard RJ , Kabbage M , Koch C , Kracher B , Kubo Y , Law AD , Lebrun MH , Lee YH , Miyara I , Moore N , Neumann U , Nordstrom K , Panaccione DG , Panstruga R , Place M , Proctor RH , Prusky D , Rech G , Reinhardt R , Rollins JA , Rounsley S , Schardl CL , Schwartz DC , Shenoy N , Shirasu K , Sikhakolli UR , Stuber K , Sukno SA , Sweigard JA , Takano Y , Takahara H , Trail F , van der Does HC , Voll LM , Will I , Young S , Zeng Q , Zhang J , Zhou S , Dickman MB , Schulze-Lefert P , Ver Loren van Themaat E , Ma LJ , Vaillancourt LJ
Ref : Nat Genet , 44 :1060 , 2012
Abstract : Colletotrichum species are fungal pathogens that devastate crop plants worldwide. Host infection involves the differentiation of specialized cell types that are associated with penetration, growth inside living host cells (biotrophy) and tissue destruction (necrotrophy). We report here genome and transcriptome analyses of Colletotrichum higginsianum infecting Arabidopsis thaliana and Colletotrichum graminicola infecting maize. Comparative genomics showed that both fungi have large sets of pathogenicity-related genes, but families of genes encoding secreted effectors, pectin-degrading enzymes, secondary metabolism enzymes, transporters and peptidases are expanded in C. higginsianum. Genome-wide expression profiling revealed that these genes are transcribed in successive waves that are linked to pathogenic transitions: effectors and secondary metabolism enzymes are induced before penetration and during biotrophy, whereas most hydrolases and transporters are upregulated later, at the switch to necrotrophy. Our findings show that preinvasion perception of plant-derived signals substantially reprograms fungal gene expression and indicate previously unknown functions for particular fungal cell types.
ESTHER : O'Connell_2012_Nat.Genet_44_1060
PubMedSearch : O'Connell_2012_Nat.Genet_44_1060
PubMedID: 22885923
Gene_locus related to this paper: colgm-kex1 , colhi-h1vve5 , colhi-h1vkk5 , colgm-e3qtg4 , colhi-h1vbq5 , colgm-e3qyh7 , colgm-e3q7u5 , colhi-h1vs61 , colgm-e3qip4 , colgm-e3qv97 , colhi-h1v665 , colgm-e3qky4 , colhi-h1vd91 , colhi-h1uvl1 , colhi-h1v7k5 , colgm-e3qu96 , colhi-h1vhh1 , colhi-h1v638 , colhi-h1vcz3 , colgm-e3qwt6 , colgm-e3q3z6 , colhi-h1vmh6 , colgm-e3qqq8 , colhi-h1v0e8 , colgm-e3qyt9 , colgm-e3qby6 , colgm-e3qsm5 , colgm-e3q6f6 , colgm-e3qwt4 , colgm-e3qb89 , colhi-h1vh96 , colgm-e3qwz9 , colgm-e3qbd3 , colgm-e3qtz0 , colhi-h1w5n4 , colgm-e3q7y3 , colgm-e3qpz1 , colhi-h1v2e4 , colgm-e3qux5 , colgm-e3qx16 , colgm-cbpya , colgm-e3q8b3

Title : The Fusarium graminearum genome reveals a link between localized polymorphism and pathogen specialization - Cuomo_2007_Science_317_1400
Author(s) : Cuomo CA , Guldener U , Xu JR , Trail F , Turgeon BG , Di Pietro A , Walton JD , Ma LJ , Baker SE , Rep M , Adam G , Antoniw J , Baldwin T , Calvo S , Chang YL , Decaprio D , Gale LR , Gnerre S , Goswami RS , Hammond-Kosack K , Harris LJ , Hilburn K , Kennell JC , Kroken S , Magnuson JK , Mannhaupt G , Mauceli E , Mewes HW , Mitterbauer R , Muehlbauer G , Munsterkotter M , Nelson D , O'Donnell K , Ouellet T , Qi W , Quesneville H , Roncero MI , Seong KY , Tetko IV , Urban M , Waalwijk C , Ward TJ , Yao J , Birren BW , Kistler HC
Ref : Science , 317 :1400 , 2007
Abstract : We sequenced and annotated the genome of the filamentous fungus Fusarium graminearum, a major pathogen of cultivated cereals. Very few repetitive sequences were detected, and the process of repeat-induced point mutation, in which duplicated sequences are subject to extensive mutation, may partially account for the reduced repeat content and apparent low number of paralogous (ancestrally duplicated) genes. A second strain of F. graminearum contained more than 10,000 single-nucleotide polymorphisms, which were frequently located near telomeres and within other discrete chromosomal segments. Many highly polymorphic regions contained sets of genes implicated in plant-fungus interactions and were unusually divergent, with higher rates of recombination. These regions of genome innovation may result from selection due to interactions of F. graminearum with its plant hosts.
ESTHER : Cuomo_2007_Science_317_1400
PubMedSearch : Cuomo_2007_Science_317_1400
PubMedID: 17823352
Gene_locus related to this paper: fusof-f9fxz4 , gibze-a8w610 , gibze-b1pdn0 , gibze-i1r9e6 , gibze-i1rda9 , gibze-i1rdk7 , gibze-i1rec8 , gibze-i1rgs0 , gibze-i1rgy0 , gibze-i1rh52 , gibze-i1rhi8 , gibze-i1rig9 , gibze-i1rip5 , gibze-i1rpg6 , gibze-i1rsg2 , gibze-i1rv36 , gibze-i1rxm5 , gibze-i1rxp8 , gibze-i1rxv5 , gibze-i1s1u3 , gibze-i1s3j9 , gibze-i1s6l7 , gibze-i1s8i8 , gibze-i1s9x4 , gibze-ppme1 , gibze-q4huy1 , gibze-i1rg17 , gibze-i1rb76 , gibze-i1s1m7 , gibze-i1s3z6 , gibze-i1rd78 , gibze-i1rgl9 , gibze-i1rjp7 , gibze-i1s1q6 , gibze-i1ri35 , gibze-i1rf76 , gibze-i1rhp3 , gibza-a0a016pda4 , gibza-a0a016pl96 , gibze-i1rjb5 , gibze-i1rkc4 , gibze-a0a1c3ylb1 , gibze-gra11 , gibze-fsl2

Title : Functional analysis of the polyketide synthase genes in the filamentous fungus Gibberella zeae (anamorph Fusarium graminearum) - Gaffoor_2005_Eukaryot.Cell_4_1926
Author(s) : Gaffoor I , Brown DW , Plattner R , Proctor RH , Qi W , Trail F
Ref : Eukaryot Cell , 4 :1926 , 2005
Abstract : Polyketides are a class of secondary metabolites that exhibit a vast diversity of form and function. In fungi, these compounds are produced by large, multidomain enzymes classified as type I polyketide synthases (PKSs). In this study we identified and functionally disrupted 15 PKS genes from the genome of the filamentous fungus Gibberella zeae. Five of these genes are responsible for producing the mycotoxins zearalenone, aurofusarin, and fusarin C and the black perithecial pigment. A comprehensive expression analysis of the 15 genes revealed diverse expression patterns during grain colonization, plant colonization, sexual development, and mycelial growth. Expression of one of the PKS genes was not detected under any of 18 conditions tested. This is the first study to genetically characterize a complete set of PKS genes from a single organism.
ESTHER : Gaffoor_2005_Eukaryot.Cell_4_1926
PubMedSearch : Gaffoor_2005_Eukaryot.Cell_4_1926
PubMedID: 16278459
Gene_locus related to this paper: gibze-q66sy0

Title : Ebelactones inhibit cutinases produced by fungal plant pathogens -
Author(s) : Koller W , Trail F , Parker DM
Ref : J Antibiot (Tokyo) , 43 :734 , 1990
PubMedID: 2380118