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| Title : A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence - Jiang_2023_Nat.Commun_14_8039 |
| Author(s) : Jiang M , Huizenga MCW , Wirt JL , Paloczi J , Amedi A , van den Berg R , Benz J , Collin L , Deng H , Di X , Driever WF , Florea BI , Grether U , Janssen APA , Hankemeier T , Heitman LH , Lam TW , Mohr F , Pavlovic A , Ruf I , van den Hurk H , Stevens AF , van der Vliet D , van der Wel T , Wittwer MB , van Boeckel CAA , Pacher P , Hohmann AG , van der Stelt M |
| Ref : Nat Commun , 14 :8039 , 2023 |
| Abstract : Jiang_2023_Nat.Commun_14_8039 |
| ESTHER : Jiang_2023_Nat.Commun_14_8039 |
| PubMedSearch : Jiang_2023_Nat.Commun_14_8039 |
| PubMedID: 38052772 |
| Title : Identification of alpha,beta-Hydrolase Domain Containing Protein 6 as a Diacylglycerol Lipase in Neuro-2a Cells - van Esbroeck_2019_Front.Mol.Neurosci_12_286 |
| Author(s) : van Esbroeck ACM , Kantae V , Di X , van der Wel T , den Dulk H , Stevens AF , Singh S , Bakker AT , Florea BI , Stella N , Overkleeft HS , Hankemeier T , van der Stelt M |
| Ref : Front Mol Neurosci , 12 :286 , 2019 |
| Abstract : van Esbroeck_2019_Front.Mol.Neurosci_12_286 |
| ESTHER : van Esbroeck_2019_Front.Mol.Neurosci_12_286 |
| PubMedSearch : van Esbroeck_2019_Front.Mol.Neurosci_12_286 |
| PubMedID: 31849602 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Activity-Based Protein Profiling Identifies alpha-Ketoamides as Inhibitors for Phospholipase A2 Group XVI - Zhou_2019_ACS.Chem.Biol_14_164 |
| Author(s) : Zhou J , Mock ED , Martella A , Kantae V , Di X , Burggraaff L , Baggelaar MP , Al-Ayed K , Bakker A , Florea BI , Grimm SH , den Dulk H , Li CT , Mulder L , Overkleeft HS , Hankemeier T , van Westen GJP , van der Stelt M |
| Ref : ACS Chemical Biology , 14 :164 , 2019 |
| Abstract : Zhou_2019_ACS.Chem.Biol_14_164 |
| ESTHER : Zhou_2019_ACS.Chem.Biol_14_164 |
| PubMedSearch : Zhou_2019_ACS.Chem.Biol_14_164 |
| PubMedID: 30620559 |
| Title : Pharmacometabolomics Informs About Pharmacokinetic Profile of Methylphenidate - Kaddurah-Daouk_2018_CPT.Pharmacometrics.Syst.Pharmacol_7_525 |
| Author(s) : Kaddurah-Daouk R , Hankemeier T , Scholl EH , Baillie R , Harms A , Stage C , Dalhoff KP , Jurgens G , Taboureau O , Nzabonimpa GS , Motsinger-Reif AA , Thomsen R , Linnet K , Rasmussen HB |
| Ref : CPT Pharmacometrics Syst Pharmacol , 7 :525 , 2018 |
| Abstract : Kaddurah-Daouk_2018_CPT.Pharmacometrics.Syst.Pharmacol_7_525 |
| ESTHER : Kaddurah-Daouk_2018_CPT.Pharmacometrics.Syst.Pharmacol_7_525 |
| PubMedSearch : Kaddurah-Daouk_2018_CPT.Pharmacometrics.Syst.Pharmacol_7_525 |
| PubMedID: 30169917 |
| Title : Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms - Amin_2017_Mol.Psychiatry_22_537 |
| Author(s) : Amin N , Jovanova O , Adams HH , Dehghan A , Kavousi M , Vernooij MW , Peeters RP , de Vrij FM , van der Lee SJ , van Rooij JG , van Leeuwen EM , Chaker L , Demirkan A , Hofman A , Brouwer RW , Kraaij R , Willems van Dijk K , Hankemeier T , van Ijcken WF , Uitterlinden AG , Niessen WJ , Franco OH , Kushner SA , Ikram MA , Tiemeier H , van Duijn CM |
| Ref : Mol Psychiatry , 22 :537 , 2017 |
| Abstract : Amin_2017_Mol.Psychiatry_22_537 |
| ESTHER : Amin_2017_Mol.Psychiatry_22_537 |
| PubMedSearch : Amin_2017_Mol.Psychiatry_22_537 |
| PubMedID: 27431295 |
| Gene_locus related to this paper: human-LIPG |
| Title : Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474 - van Esbroeck_2017_Science_356_1084 |
| Author(s) : van Esbroeck ACM , Janssen APA , Cognetta AB, 3rd , Ogasawara D , Shpak G , van der Kroeg M , Kantae V , Baggelaar MP , de Vrij FMS , Deng H , Allara M , Fezza F , Lin Z , van der Wel T , Soethoudt M , Mock ED , den Dulk H , Baak IL , Florea BI , Hendriks G , De Petrocellis L , Overkleeft HS , Hankemeier T , De Zeeuw CI , Di Marzo V , Maccarrone M , Cravatt BF , Kushner SA , van der Stelt M |
| Ref : Science , 356 :1084 , 2017 |
| Abstract : van Esbroeck_2017_Science_356_1084 |
| ESTHER : van Esbroeck_2017_Science_356_1084 |
| PubMedSearch : van Esbroeck_2017_Science_356_1084 |
| PubMedID: 28596366 |
| Title : Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons - Baggelaar_2015_J.Am.Chem.Soc_137_8851 |
| Author(s) : Baggelaar MP , Chameau PJ , Kantae V , Hummel J , Hsu KL , Janssen F , van der Wel T , Soethoudt M , Deng H , den Dulk H , Allara M , Florea BI , Di Marzo V , Wadman WJ , Kruse CG , Overkleeft HS , Hankemeier T , Werkman TR , Cravatt BF , van der Stelt M |
| Ref : Journal of the American Chemical Society , 137 :8851 , 2015 |
| Abstract : Baggelaar_2015_J.Am.Chem.Soc_137_8851 |
| ESTHER : Baggelaar_2015_J.Am.Chem.Soc_137_8851 |
| PubMedSearch : Baggelaar_2015_J.Am.Chem.Soc_137_8851 |
| PubMedID: 26083464 |
| Gene_locus related to this paper: human-DAGLA , human-DAGLB |
| Title : Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics - Rasmussen_2015_Pharmacogenomics_16_649 |
| Author(s) : Rasmussen HB , Bjerre D , Linnet K , Jurgens G , Dalhoff K , Stefansson H , Hankemeier T , Kaddurah-Daouk R , Taboureau O , Brunak S , Houmann T , Jeppesen P , Pagsberg AK , Plessen K , Dyrborg J , Hansen PR , Hansen PE , Hughes T , Werge T |
| Ref : Pharmacogenomics , 16 :649 , 2015 |
| Abstract : Rasmussen_2015_Pharmacogenomics_16_649 |
| ESTHER : Rasmussen_2015_Pharmacogenomics_16_649 |
| PubMedSearch : Rasmussen_2015_Pharmacogenomics_16_649 |
| PubMedID: 25896426 |