Gene_locus Report for: aspfu-kex1

Other strains: Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGS A1100)Neosartorya fischeri (strain CEA10 / CBS 144.89 / FGSC A1163)(), (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL181) (Aspergillus fischerianus)

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Fungi: N E > Dikarya: N E > Ascomycota: N E > saccharomyceta: N E > Pezizomycotina: N E > leotiomyceta: N E > Eurotiomycetes: N E > Eurotiomycetidae: N E > Eurotiales: N E > Aspergillaceae: N E > Aspergillus: N E > Aspergillus fumigatus: N E

6_AlphaBeta_hydrolase : aspfc-b0xp50Neosartorya fumigata, (Aspergillus fumigatus), Neosartorya fischeri (Aspergillus fischerianus), Putative uncharacterized protein, aspfc-b0xzj6Neosartorya fumigata (strains CEA10 / CBS 144.89 / FGSC A1163; ATCC MYA-4609 / Af293 / CBS 101355 / FGS A1100) (Aspergillus fumigatus) Putative uncharacterized protein, aspfu-q4wpb9Neosartorya fumigata (strains ATCC MYA-4609 / Af293 / CBS 101355 / FGS A1100; CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus) Putative uncharacterized protein.
Acidic_Lipase : aspfc-b0xu40Neosartorya fumigata (Aspergillus fumigatus) Neosartorya fumigata (Aspergillus fumigatus) Neosartorya fischeri (Aspergillus fischerianus) Ab-hydrolase associated lipase, putative.
Canar_LipB : aspfu-q4wg73 Neosartorya fumigata (Aspergillus fumigatus) Lipase, putative.
CFTR-inhibitory-factor_Cif : aspfc-b0y962Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus) Alpha/beta hydrolase, putative.
Fungal-Bact_LIP : aspfc-b0y2h6Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus) Lipase, putative.
Haloalkane_dehalogenase-HLD1 : aspfc-b0yaj6Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus) Haloalkane dehalogenase family protein.
Prolylcarboxypeptidase : aspfu-q4wzd5Aspergillus fumigatus, Neosartorya fischeri (Aspergillus fischerianus), Neosartorya fumigata (Aspergillus fumigatus) serine peptidase, family s28, putative.
Thiohydrolase : aspfu-fmacNeosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus). Fumagillin biosynthesis acyltransferase

Title: Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
Nierman WC, Pain A, Anderson MJ, Wortman JR, Kim HS, Arroyo J, Berriman M, Abe K, Archer DB and Denning DW <87 more author(s)> Nierman WC, Pain A, Anderson MJ, Wortman JR, Kim HS, Arroyo J, Berriman M, Abe K, Archer DB, Bermejo C, Bennett J, Bowyer P, Chen D, Collins M, Coulsen R, Davies R, Dyer PS, Farman M, Fedorova N, Feldblyum TV, Fischer R, Fosker N, Fraser A, Garcia JL, Garcia MJ, Goble A, Goldman GH, Gomi K, Griffith-Jones S, Gwilliam R, Haas B, Haas H, Harris D, Horiuchi H, Huang J, Humphray S, Jimenez J, Keller N, Khouri H, Kitamoto K, Kobayashi T, Konzack S, Kulkarni R, Kumagai T, Lafon A, Latge JP, Li W, Lord A, Lu C, Majoros WH, May GS, Miller BL, Mohamoud Y, Molina M, Monod M, Mouyna I, Mulligan S, Murphy L, O'Neil S, Paulsen I, Penalva MA, Pertea M, Price C, Pritchard BL, Quail MA, Rabbinowitsch E, Rawlins N, Rajandream MA, Reichard U, Renauld H, Robson GD, Rodriguez de Cordoba S, Rodriguez-Pena JM, Ronning CM, Rutter S, Salzberg SL, Sanchez M, Sanchez-Ferrero JC, Saunders D, Seeger K, Squares R, Squares S, Takeuchi M, Tekaia F, Turner G, Vazquez de Aldana CR, Weidman J, White O, Woodward J, Yu JH, Fraser C, Galagan JE, Asai K, Machida M, Hall N, Barrell B, Denning DW (- 87)
Ref: Nature, 438:1151, 2005 : PubMed
Abstract


ESTHER: Nierman_2005_Nature_438_1151
PubMedSearch: Nierman 2005 Nature 438 1151
PubMedID: 16372009
Gene_locus related to this paper: aspfc-b0xp50, aspfc-b0xu40, aspfc-b0xzj6, aspfc-dpp5, aspfu-apth1, aspfu-axe1, aspfu-CBPYA, aspfu-faec, aspfu-kex1, aspfu-ppme1, aspfu-q4wa39, aspfu-q4wa78, aspfu-q4wf56, aspfu-q4wg73, aspfu-q4wk44, aspfu-q4wkh6, aspfu-q4wnx3, aspfu-q4wpb9, aspfu-q4wqv2, aspfu-q4wub2, aspfu-q4wxr1, aspfu-q4x0n6, aspfu-q4x1n0, aspfu-q5vjg7, neofi-a1cwa6, neofi-a1dfr9, aspfm-a0a084bf80, aspfu-fmac

Abstract

Aspergillus fumigatus is exceptional among microorganisms in being both a primary and opportunistic pathogen as well as a major allergen. Its conidia production is prolific, and so human respiratory tract exposure is almost constant. A. fumigatus is isolated from human habitats and vegetable compost heaps. In immunocompromised individuals, the incidence of invasive infection can be as high as 50% and the mortality rate is often about 50% (ref. 2). The interaction of A. fumigatus and other airborne fungi with the immune system is increasingly linked to severe asthma and sinusitis. Although the burden of invasive disease caused by A. fumigatus is substantial, the basic biology of the organism is mostly obscure. Here we show the complete 29.4-megabase genome sequence of the clinical isolate Af293, which consists of eight chromosomes containing 9,926 predicted genes. Microarray analysis revealed temperature-dependent expression of distinct sets of genes, as well as 700 A. fumigatus genes not present or significantly diverged in the closely related sexual species Neosartorya fischeri, many of which may have roles in the pathogenicity phenotype. The Af293 genome sequence provides an unparalleled resource for the future understanding of this remarkable fungus.