Malathion
insecticide, lipid soluble. Oxidises to Malaoxon which is more toxic
General
Type : Insecticide, Acaricide, Organophosphate, Sulfur Compound, Organothiophosphate
Chemical_Nomenclature : diethyl 2-dimethoxyphosphinothioylsulfanylbutanedioate
Canonical SMILES : CCOC(=O)CC(C(=O)OCC)SP(=S)(OC)OC
InChI : InChI=1S\/C10H19O6PS2\/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4\/h8H,5-7H2,1-4H3
InChIKey : JXSJBGJIGXNWCI-UHFFFAOYSA-N
Other name(s) : O,O'-dimethyl S-(1,2-dicarboxyethoxyethyl) phosphorothiolothionate or phosphorodithioate || s-(1,2-dicarbethoxyethyl) O,O'-dimethyldithiophosphate || O,O'-dimethyl S-(1,2-dicarbethoxyethyl) thiothionophosphate || Malothon || Phosphoton || Cythion || calmathion || carbetox || carbethoxy malathion || arbetovur || celthion || cimexan || compound 4049 || detmol ma || Malaspray || Ethiolacar || Etiol || Cleensheen || Lice Rid || Carbophos || Maldison || Mercaptothion
MW : 330.36
Formula : C10H19O6PS2
CAS_number : 121-75-5
PubChem : 4004
UniChem : JXSJBGJIGXNWCI-UHFFFAOYSA-N
Wikipedia : Malathion
Target
Families : Malathion ligand of proteins in family
ACHE
References (62)
| Title : Evaluation of insecticide resistance and biochemical mechanisms in a population of culex quinquefasciatus (Diptera: Culicidae) from Sao Paulo, Brazil - Bracco_1999_Mem.Inst.Oswaldo.Cruz_94_115 |
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| Abstract : |
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| Title : Dimethylphosphorus metabolites in serum and urine of persons poisoned by malathion or thiometon - Vasilic_1999_Chem.Biol.Interact_119-120_479 |
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| Title : The use of biomarkers to measure the interactive effects of chemicals - Walker_1998_Ecotoxicol.Environ.Saf_40_65 |
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| Title : Susceptibility of Lutzomyia longipalpis (Diptera: Psychodidae) to selected insecticides in an endemic focus of visceral leishmaniasis in Venezuela - Mazzarri_1997_J.Am.Mosq.Control.Assoc_13_335 |
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| Title : [Determination of insecticide resistance and its biochemical mechanisms in 2 strains of Culex quinquefasciatus from Santiago de Cuba] - Rodriguez_1997_Rev.Cubana.Med.Trop_49_209 |
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| Title : Effect of administration of malathion for 14 days on macrophage function and mast cell degranulation - Rodgers_1997_Fundam.Appl.Toxicol_37_95 |
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| Title : Human mortality in organophosphate poisonings - Yamashita_1997_Vet.Hum.Toxicol_39_84 |
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| Title : Effects of organophosphate and carbamate pesticides on acetylcholinesterase and choline acetyltransferase activities of the polychaete Nereis diversicolor - Scaps_1997_Arch.Environ.Contam.Toxicol_33_203 |
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| Title : Evaluation of organophosphorus pesticide residues in citrus fruits from the Valencian community (Spain) - Torres_1997_J.AOAC.Int_80_1122 |
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| Title : Renal effects of chronic exposure to malathion in Octodon degus - Bosco_1997_Comp.Biochem.Physiol.C.Pharmacol.Toxicol.Endocrinol_118_247 |
| Author(s) : Bosco C , Rodrigo R , Diaz S , Borax J |
| Ref : Comparative Biochemistry & Physiology C Pharmacology Toxicology & Endocrinology , 118 :247 , 1997 |
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| Title : Organophosphate resistance in Culex pipiens from Cyprus - Wirth_1996_J.Am.Mosq.Control.Assoc_12_112 |
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| Title : Organohalogen and organophosphorus pesticides in mixed feed rations: findings from FDA's domestic surveillance during fiscal years 1989-1994 - Lovell_1996_J.AOAC.Int_79_544 |
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| Title : Yellowfever mosquito (Diptera:Culicidae) introduced into Landi Kotal, Pakistan, by tire importation - Suleman_1996_J.Med.Entomol_33_689 |
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| Title : Efficiency of some technological processes on reducing the residues of malathion and pirimiphos methyl in mature broad bean seeds - Kamil_1996_Nahrung_40_277 |
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| Title : Selective, solid-matrix dispersion extraction of organophosphate pesticide residues from milk - Di Muccio_1996_J.Chromatogr.A_754_497 |
| Author(s) : Di Muccio A , Pelosi P , Camoni I , Attard Barbini D , Dommarco R , Generali T , Ausili A |
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| Title : Fenitrothion intoxication during spraying operations in the malaria programme for Afghan refugees in North West Frontier Province of Pakistan - Bouma_1995_Trop.Geog.Med_47_12 |
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| Title : Effects of three organophosphorus insecticides in the reproductive potential of Culex quinquefasciatus - Aguilera_1995_Mem.Inst.Oswaldo.Cruz_90_411 |
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| Title : Anopheles culicifacies in Baluchistan, Iran - Zaim_1995_Med.Vet.Entomol_9_181 |
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| Title : A resistance of head lice (Pediculus capitis) to permethrin in Czech Republic - Rupes_1995_Cent.Eur.J.Public.Health_3_30 |
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| Title : The study of interactive effects of pollutants: a biomarker approach. - Johnston_1995_Sci.Tot.Environ_171_205 |
| Author(s) : Johnston G |
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| Title : Insecticide susceptibility in mosquitoes (Diptera: Culicidae) from French Polynesia - Failloux_1994_J.Med.Entomol_31_639 |
| Author(s) : Failloux AB , Ung A , Raymond M , Pasteur N |
| Ref : Journal of Medical Entomology , 31 :639 , 1994 |
| Abstract : |
| PubMedSearch : Failloux_1994_J.Med.Entomol_31_639 |
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| Title : Isolation of an esterase conferring insecticide resistance in the mosquito Culex tarsalis - Whyard_1994_Insect.Biochem.Mol.Biol_24_819 |
| Author(s) : Whyard S , Downe AE , Walker VK |
| Ref : Insect Biochemistry & Molecular Biology , 24 :819 , 1994 |
| Abstract : |
| PubMedSearch : Whyard_1994_Insect.Biochem.Mol.Biol_24_819 |
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| Title : Insecticide resistance and malathion carboxylesterase in the sheep blowfly, Lucilia cuprina - Whyard_1994_Biochem.Genet_32_9 |
| Author(s) : Whyard S , Russell RJ , Walker VK |
| Ref : Biochemical Genetics , 32 :9 , 1994 |
| Abstract : |
| PubMedSearch : Whyard_1994_Biochem.Genet_32_9 |
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| Title : Susceptibility of the bedbug, Cimex lectularius, to selected insecticides and various treated surfaces - Fletcher_1993_Med.Vet.Entomol_7_69 |
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| Ref : Med Vet Entomol , 7 :69 , 1993 |
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| PubMedSearch : Fletcher_1993_Med.Vet.Entomol_7_69 |
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| Title : [A study on acute organophosphorus poisoning--changes in the activity and isoenzyme patterns of serum cholinesterase in human poisoning]. [Japanese] - Yamanaka_1993_Japanese.J.Hyg_48_955 |
| Author(s) : Yamanaka S , Yoshida M , Yamamura Y , Nishimura M , Takaesu Y |
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| Title : Changes in malathion and pyrethroid resistance after cypermethrin selection of Culex quinquefasciatus field populations of Cuba - Rodriguez_1993_Med.Vet.Entomol_7_117 |
| Author(s) : Rodriguez M , Ortiz E , Bisset JA , Hemingway J , Saledo E |
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| Title : Control of Mansonia mosquitos, vectors of brugian filariasis in Sarawak, Malaysia - Chang_1993_Southeast.Asian.J.Trop.Med.Public.Health_2_93 |
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| Title : Correlation of the anticholinesterase activity of a series of organophosphates with their ability to compete with agonist binding to muscarinic receptors - Ward_1993_Toxicol.Appl.Pharmacol_122_300 |
| Author(s) : Ward TR , Ferris DJ , Tilson HA , Mundy WR |
| Ref : Toxicology & Applied Pharmacology , 122 :300 , 1993 |
| Abstract : |
| PubMedSearch : Ward_1993_Toxicol.Appl.Pharmacol_122_300 |
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| Title : Insecticide susceptibility status & enzyme profile of Aedes albopictus populations from different localities of Maharashtra state - Chakraborti_1993_Indian.J.Med.Res_97_37 |
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| Title : Synthesis, absolute configuration, and analysis of malathion, malaoxon, and isomalathion enantiomers [published erratum appears in Chem Res Toxicol 1994 Mar-Apr\;7(2):275] - Berkman_1993_Chem.Res.Toxicol_6_718 |
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| Title : Insecticide resistance gene frequencies in Anopheles sacharovi populations of the Cukurova plain, Adana Province, Turkey - Hemingway_1992_Med.Vet.Entomol_6_342 |
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| Title : Determination of organophosphorous and carbamate insecticides by flow injection analysis - Kumaran_1992_Anal.Biochem_200_187 |
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| PubMedSearch : Kumaran_1992_Anal.Biochem_200_187 |
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| Title : The effect of malathion, an organophosphate, on the plasma FSH, 17 beta-estradiol and progesterone concentrations and acetylcholinesterase activity and conception in dairy cattle - Prakash_1992_Vet.Hum.Toxicol_34_116 |
| Author(s) : Prakash N , Narayana K , Murthy GS , Moudgal NR , Honnegowda |
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| Title : Malathion and pyrethroid resistance in Culex quinquefasciatus from Cuba: efficacy of pirimiphos-methyl in the presence of at least three resistance mechanisms - Bisset_1991_Med.Vet.Entomol_5_223 |
| Author(s) : Bisset JA , Rodriguez MM , Hemingway J , Diaz C , Small GJ , Ortiz E |
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| Title : Effectiveness of certain drugs in acute malathion intoxication in rats - Husain_1990_Ecotoxicol.Environ.Saf_19_271 |
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| Title : Simple analytical method for organophosphorus pesticide residues in milk - Toyoda_1990_J.Assoc.Off.Anal.Chem_73_770 |
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| Title : Profile of drug metabolizing enzymes in rats treated with parathion, malathion, and phosalone under various conditions of protein energy malnutrition - |
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| Title : Evaluation of mutagenic activities of endosulfan, phosalone, malathion, and permethrin, before and after metabolic activation, in the Ames Salmonella test - |
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| Title : Effect of subacute administration of three organophosphorus pesticides on the hepatic phosphatases under various nutritional conditions - Bulusu_1987_Environ.Res_44_126 |
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| Title : An enzyme test for determining isomalathion impurities in water-dispersible powders of malathion - Reiner_1986_Bull.World.Health.Organ_64_397 |
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| Title : Mutagenic and alkylating activities of organophosphate impurities of commercial malathion - Imamura_1985_Mutat.Res_155_1 |
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| Title : Toxicological properties of trialkyl phosphorothioate and dialkyl alkyl- and arylphosphonothioate esters - Fukuto_1983_J.Environ.Sci.Health.B_18_89 |
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| Title : Effect of selected pesticides on alkaline and acid phosphatase in the rat - Saigal_1982_Toxicol.Lett_12_177 |
| Author(s) : Saigal S , Bhatnagar VK , Malviya AN |
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| Title : A large-scale evaluation of pirimiphos-methyl 25\% WP during 1980-1981 for malaria control in Pakistan - Nasir_1982_J.Trop.Med.Hyg_85_239 |
| Author(s) : Nasir SM , Ahmad N , Shah MA , Azam CM |
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| Title : Observations on the accidental poisoning of birds by organophosphate insecticides and other toxic substances - Reece_1982_Vet.Rec_111_453 |
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| Title : Electroretinographic study of the white mouse intoxicated by organo- phosphorus: mevinphos and malathion - Carricaburu_1981_Toxicol.Eur.Res_3_87 |
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| Title : Residual toxicity of wall-sprayed organophosphates, carbamates and pyrethroids to mosquito Culex pipiens molestus Forskal - Rettich_1980_J.Hyg.Epidemiol.Microbiol.Immunol_24_110 |
| Author(s) : Rettich F |
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| Title : Properties and inhibition of rat malathion carboxylesterases - Mallipudi_1980_J.Toxicol.Environ.Health_6_585 |
| Author(s) : Mallipudi NM , Talcott RE , Ketterman A , Fukuto TR |
| Ref : J Toxicol Environ Health , 6 :585 , 1980 |
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| Title : Isolation and concentration of organophosphorus pesticides from drinking water at the ng\/L level, using macroreticular resin - LeBel_1979_J.Assoc.Off.Anal.Chem_62_241 |
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| Title : Malathion carboxylesterase activity in human liver and its inactivation by isomalathion - |
| Author(s) : Talcott RE , Denk H , Mallipudi NM |
| Ref : Toxicol Appl Pharmacol , 49 :373 , 1979 |
| PubMedID: 494286 |
| Title : Insecticide residues in milled fractions of dry or tough wheat treated with malathion, bromophos, iodofenphos, and pirimiphos-methyl - |
| Author(s) : Mensah GW , Watters FL , Webster GR |
| Ref : J Econ Entomol , 72 :728 , 1979 |
| PubMedID: 544641 |
| Title : The toxicological properties of impurities in malathion - Aldridge_1979_Arch.Toxicol_42_95 |
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| Ref : Archives of Toxicology , 42 :95 , 1979 |
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| PubMedSearch : Aldridge_1979_Arch.Toxicol_42_95 |
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| Title : Evaluation of cytotoxic responses caused by selected organophosphorus esters in chick sympathetic ganglia cultures - Obersteiner_1978_Can.J.Comp.Med_42_80 |
| Author(s) : Obersteiner EJ , Sharma RP |
| Ref : Can J Comp Med , 42 :80 , 1978 |
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| Title : Epidemic malathion poisoning in Pakistan malaria workers - Baker_1978_Lancet_1_31 |
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| Title : Correlation between organophosphate poisoning, acetylcholinesterase inhibition, and increased cyclic GMP levels in malathion-treated insects - Bodnaryk_1977_Can.J.Biochem_55_534 |
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| Title : Nonoxidative enzymes in the metabolism of insecticides - Ahmad_1976_Ann.Clin.Biochem_13_141 |
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