Derivative of berberine

Inhibitor	Main targeted enzyme families	Type	Structure
Columbamine	ACHE	Natural Alkaloid Not AlphaBeta Hydrolase target Isoquinoline Derivative of berberine
Palmatine	ACHE	Natural Alkaloid Not AlphaBeta Hydrolase target Isoquinoline Derivative of berberine
Berberine	ACHE BCHE	Natural Alkaloid Not AlphaBeta Hydrolase target Isoquinoline Benzodioxo Antioxidant Derivative of berberine
Canadine	ACHE BCHE Cholinesterase	Natural Alkaloid Derivative of berberine
sEH-inhibitor-19	Epoxide_hydrolase	Natural Alkaloid Isoquinoline Trifluoro Urea derivative Derivative of berberine
Thalictricavine	ACHE BCHE Cholinesterase	Natural Alkaloid Derivative of berberine
Jatrorrhizine	ACHE	Natural Alkaloid Not AlphaBeta Hydrolase target Isoquinoline Derivative of berberine