PPARgamma ligand
General
Not an alpha/beta hydrolase target but can be used as a building block for larger inhibitors of enzymes of the family designed as multitarget compounds. PPARs are ligand-activated transcription factors that are involved in the expression of more than 100 genes and affect numerous metabolic processes, most notably lipid and glucose homeostasis. Promoting insulin sensitivity and the improved uptake of blood glucose. Used as building blocks of Multi-target drug ligand MTDL
