Feau N

References (3)

Title : Diverse lifestyles and strategies of plant pathogenesis encoded in the genomes of eighteen Dothideomycetes fungi - Ohm_2012_PLoS.Pathog_8_e1003037
Author(s) : Ohm RA , Feau N , Henrissat B , Schoch CL , Horwitz BA , Barry KW , Condon BJ , Copeland AC , Dhillon B , Glaser F , Hesse CN , Kosti I , LaButti K , Lindquist EA , Lucas S , Salamov AA , Bradshaw RE , Ciuffetti L , Hamelin RC , Kema GH , Lawrence C , Scott JA , Spatafora JW , Turgeon BG , de Wit PJ , Zhong S , Goodwin SB , Grigoriev IV
Ref : PLoS Pathog , 8 :e1003037 , 2012
Abstract : The class Dothideomycetes is one of the largest groups of fungi with a high level of ecological diversity including many plant pathogens infecting a broad range of hosts. Here, we compare genome features of 18 members of this class, including 6 necrotrophs, 9 (hemi)biotrophs and 3 saprotrophs, to analyze genome structure, evolution, and the diverse strategies of pathogenesis. The Dothideomycetes most likely evolved from a common ancestor more than 280 million years ago. The 18 genome sequences differ dramatically in size due to variation in repetitive content, but show much less variation in number of (core) genes. Gene order appears to have been rearranged mostly within chromosomal boundaries by multiple inversions, in extant genomes frequently demarcated by adjacent simple repeats. Several Dothideomycetes contain one or more gene-poor, transposable element (TE)-rich putatively dispensable chromosomes of unknown function. The 18 Dothideomycetes offer an extensive catalogue of genes involved in cellulose degradation, proteolysis, secondary metabolism, and cysteine-rich small secreted proteins. Ancestors of the two major orders of plant pathogens in the Dothideomycetes, the Capnodiales and Pleosporales, may have had different modes of pathogenesis, with the former having fewer of these genes than the latter. Many of these genes are enriched in proximity to transposable elements, suggesting faster evolution because of the effects of repeat induced point (RIP) mutations. A syntenic block of genes, including oxidoreductases, is conserved in most Dothideomycetes and upregulated during infection in L. maculans, suggesting a possible function in response to oxidative stress.
ESTHER : Ohm_2012_PLoS.Pathog_8_e1003037
PubMedSearch : Ohm_2012_PLoS.Pathog_8_e1003037
PubMedID: 23236275
Gene_locus related to this paper: mycpj-q30dw8 , sphms-m3db71 , bauco-m2n3p9 , cocsn-m2rnc6 , coch5-m2tnl8 , coch4-n4xap8 , sett2-r0j560 , bauco-m2lw45 , cocsn-m2thl9 , bauco-m2nan7 , sphms-m3asf7 , coch5-m2v1s2 , mycfi-m3am36 , coch4-n4xzy1 , mycfi-m3b3x0 , cocsn-m2sqr3 , cocsn-m2rnk8 , mycp1-n1pnd6 , bauco-m2n7y7 , coch4-n4xdv7 , coch5-m2uds0 , coch5-m2um94 , sett2-r0i8c5 , coch4-n4wlc8 , coch4-n4x9p3 , cocsn-m2rh47 , cocsn-m2qz08 , sett2-r0jqq6 , mycfi-m2yiq2 , sett2-r0imb6 , sphms-m3b727 , coch4-n4x7u3 , cocsn-m2rv02 , cocsn-m2sy95 , coch5-m2ubd5 , mycp1-n1per0 , mycp1-n1pg49 , mycfi-n1q8u1 , mycp1-n1pwj1 , mycp1-n1pcl8 , bauco-m2n330 , cocsn-m2t3d2 , mycfi-m3b223 , sett2-r0kl84 , bauco-m2lu86 , mycfi-m3b1s8 , sett2-r0jts7 , mycfi-m3amn9 , bauco-m2nf03 , mycfi-m3a015 , sphms-n1qgv4 , coch4-n4x2h3 , mycp1-m2y2b1 , sett2-r0jxt9 , mycfi-m2zg05 , sphms-m3cr09 , coch4-n4x7r9 , mycfi-m2yip7 , mycp1-n1pwu7 , cocsn-m2sh75 , cocsn-m2t5z2 , coch5-m2ucf6 , sphms-m3c9s8 , sphms-m3c383 , mycp1-n1ppa8 , sett2-r0k664 , cocsn-m2t3q1 , sett2-r0k4b4 , cocsn-m2t4i1 , bauco-m2lzw1 , coch5-m2th93 , cocsn-m2svm8 , sphms-m3d7h2 , sphms-m3cwc3 , mycfi-m3b329 , bauco-m2n4x9 , cocsn-m2s6q4 , mycfi-m3b7x7 , mycp1-m2yk59 , cocsn-m2s5h5 , bauco-m2nfr9 , bauco-m2myk4 , coch4-n4xf94 , mycfi-m3a252 , sphms-n1qes8 , mycp1-n1pps5 , sett2-r0kdl8 , cocsn-m2qvi9 , sett2-r0kfg6 , bauco-m2n1q0 , cocsn-m2szq4 , sett2-r0j437 , coch4-n4x7j4 , mycfi-m3b4h3 , coch5-m2twk3 , coch5-m2usf2 , sett2-r0kjt7 , mycfi-m2yrk1 , bauco-m2n4g8 , sett2-r0k7y2 , cocsn-m2th03 , sett2-r0iy92 , sett2-r0kbr9 , sett2-r0k997 , coch5-m2sik6 , bauco-m2n0g0 , bauco-m2lkk0 , sett2-r0jzj5 , sphms-m3bs21 , mycfi-m3a3h8 , mycp1-n1pw13 , cocsn-m2r0j6 , mycp1-n1pe19 , coch4-n4x6a4 , mycp1-m2xhl1 , cocsn-m2s7a5 , cocsn-m2sv79 , mycfi-n1qbd7 , mycp1-n1pnh6 , sphms-m3cz62 , sett2-r0knx4 , bauco-m2nlz2 , mycp1-n1psn5 , sett2-r0ksh8 , bauco-m2n3v9 , bauco-m2n9y7 , mycp1-n1puh9 , sett2-r0ip86 , sphms-m3c6j1 , sphms-n1qnq9 , cocsn-m2sqe4 , coch4-n4xzc8 , mycfi-m3ali0 , mycfi-m3a5j4 , mycp1-n1phf7 , bauco-m2myw5 , mycp1-m2y2h4 , mycfi-m3as05 , sphms-m3ccg5 , cocsn-m2rtg8 , sphms-n1qny5 , mycfi-n1q7c3 , mycp1-n1q523 , bauco-m2m190 , psefd-m3awp8 , sphms-n1qfl1 , dotsn-n1q1b1 , sphms-m3dcu2 , bauco-m2m7v7 , psefd-m3bad8 , bauco-m2nft5 , psefd-m3b4x7 , sphms-n1qdh4 , sphms-m3cq38 , bauco-m2mz43 , coch5-m2t2x3 , cocsn-m2sze4 , sphms-n1qfm9 , sett2-r0kjg6 , sett2-r0k5q0 , cocvi-w7ezb7 , sett2-r0jtm1 , cocmi-w6ywa1 , psefd-m3a663 , baupa-m2mxl2 , cocsn-m2t3e8 , coch5-m2ulw5 , coch5-m2urw9 , sett2-r0knn5 , cocca-w6y1v2 , baupa-m2nq79 , sett2-r0i9k2 , coch5-m2uul8 , dotsn-n1q415 , psefd-n1qcy3 , cocsn-m2sl21 , baupa-m2luc8 , dotsn-est1

Title : Obligate biotrophy features unraveled by the genomic analysis of rust fungi - Duplessis_2011_Proc.Natl.Acad.Sci.U.S.A_108_9166
Author(s) : Duplessis S , Cuomo CA , Lin YC , Aerts A , Tisserant E , Veneault-Fourrey C , Joly DL , Hacquard S , Amselem J , Cantarel BL , Chiu R , Coutinho PM , Feau N , Field M , Frey P , Gelhaye E , Goldberg J , Grabherr MG , Kodira CD , Kohler A , Kues U , Lindquist EA , Lucas SM , Mago R , Mauceli E , Morin E , Murat C , Pangilinan JL , Park R , Pearson M , Quesneville H , Rouhier N , Sakthikumar S , Salamov AA , Schmutz J , Selles B , Shapiro H , Tanguay P , Tuskan GA , Henrissat B , Van de Peer Y , Rouze P , Ellis JG , Dodds PN , Schein JE , Zhong S , Hamelin RC , Grigoriev IV , Szabo LJ , Martin F
Ref : Proc Natl Acad Sci U S A , 108 :9166 , 2011
Abstract : Rust fungi are some of the most devastating pathogens of crop plants. They are obligate biotrophs, which extract nutrients only from living plant tissues and cannot grow apart from their hosts. Their lifestyle has slowed the dissection of molecular mechanisms underlying host invasion and avoidance or suppression of plant innate immunity. We sequenced the 101-Mb genome of Melampsora larici-populina, the causal agent of poplar leaf rust, and the 89-Mb genome of Puccinia graminis f. sp. tritici, the causal agent of wheat and barley stem rust. We then compared the 16,399 predicted proteins of M. larici-populina with the 17,773 predicted proteins of P. graminis f. sp tritici. Genomic features related to their obligate biotrophic lifestyle include expanded lineage-specific gene families, a large repertoire of effector-like small secreted proteins, impaired nitrogen and sulfur assimilation pathways, and expanded families of amino acid and oligopeptide membrane transporters. The dramatic up-regulation of transcripts coding for small secreted proteins, secreted hydrolytic enzymes, and transporters in planta suggests that they play a role in host infection and nutrient acquisition. Some of these genomic hallmarks are mirrored in the genomes of other microbial eukaryotes that have independently evolved to infect plants, indicating convergent adaptation to a biotrophic existence inside plant cells.
ESTHER : Duplessis_2011_Proc.Natl.Acad.Sci.U.S.A_108_9166
PubMedSearch : Duplessis_2011_Proc.Natl.Acad.Sci.U.S.A_108_9166
PubMedID: 21536894
Gene_locus related to this paper: pucgt-e3k840 , pucgt-e3kaq6 , pucgt-e3kw59 , pucgt-e3kz16 , pucgt-e3l9v6 , pucgt-e3l279 , pucgt-h6qt25 , mellp-f4reh4 , mellp-f4rhc8 , mellp-f4reh2 , mellp-f4r3y0 , mellp-f4rz15 , mellp-f4rz64 , mellp-f4rl14 , mellp-f4rz66 , mellp-f4s751 , mellp-f4s2g6 , pucgt-e3l1z7 , pucgt-e3l803 , pucgt-e3kst2 , pucgt-e3kst5 , mellp-f4ru03 , pucgt-e3l1z8 , pucgt-e3ktz7 , pucgt-e3jun4 , mellp-f4rl65 , mellp-f4rz16 , mellp-f4ru02 , mellp-f4sav4 , mellp-f4sav3 , mellp-f4s1j0 , mellp-f4rkp0 , mellp-f4s483 , pucgt-e3kzu5 , pucgt-h6qtq8 , mellp-f4r5l5 , pucgt-e3krw7 , pucgt-e3l7w5 , pucgt-e3k2w6 , pucgt-e3kfg2 , pucgt-kex1

Title : Genome and transcriptome analyses of the mountain pine beetle-fungal symbiont Grosmannia clavigera, a lodgepole pine pathogen - DiGuistini_2011_Proc.Natl.Acad.Sci.U.S.A_108_2504
Author(s) : DiGuistini S , Wang Y , Liao NY , Taylor G , Tanguay P , Feau N , Henrissat B , Chan SK , Hesse-Orce U , Alamouti SM , Tsui CK , Docking RT , Levasseur A , Haridas S , Robertson G , Birol I , Holt RA , Marra MA , Hamelin RC , Hirst M , Jones SJ , Bohlmann J , Breuil C
Ref : Proc Natl Acad Sci U S A , 108 :2504 , 2011
Abstract : In western North America, the current outbreak of the mountain pine beetle (MPB) and its microbial associates has destroyed wide areas of lodgepole pine forest, including more than 16 million hectares in British Columbia. Grosmannia clavigera (Gc), a critical component of the outbreak, is a symbiont of the MPB and a pathogen of pine trees. To better understand the interactions between Gc, MPB, and lodgepole pine hosts, we sequenced the approximately 30-Mb Gc genome and assembled it into 18 supercontigs. We predict 8,314 protein-coding genes, and support the gene models with proteome, expressed sequence tag, and RNA-seq data. We establish that Gc is heterothallic, and report evidence for repeat-induced point mutation. We report insights, from genome and transcriptome analyses, into how Gc tolerates conifer-defense chemicals, including oleoresin terpenoids, as they colonize a host tree. RNA-seq data indicate that terpenoids induce a substantial antimicrobial stress in Gc, and suggest that the fungus may detoxify these chemicals by using them as a carbon source. Terpenoid treatment strongly activated a approximately 100-kb region of the Gc genome that contains a set of genes that may be important for detoxification of these host-defense chemicals. This work is a major step toward understanding the biological interactions between the tripartite MPB/fungus/forest system.
ESTHER : DiGuistini_2011_Proc.Natl.Acad.Sci.U.S.A_108_2504
PubMedSearch : DiGuistini_2011_Proc.Natl.Acad.Sci.U.S.A_108_2504
PubMedID: 21262841
Gene_locus related to this paper: grocl-dapb , grocl-f0x6y5 , grocl-f0x7n2 , grocl-f0x8u4 , grocl-f0x9c7 , grocl-f0x9d5 , grocl-f0x966 , grocl-f0xbs9 , grocl-f0xc51 , grocl-f0xcj4 , grocl-f0xee9 , grocl-f0xh50 , grocl-f0xip5 , grocl-f0xjv7 , grocl-f0xk48 , grocl-f0xke2 , grocl-f0xkp2 , grocl-f0xl11 , grocl-f0xl25 , grocl-f0xlh9 , grocl-f0xm76 , grocl-f0xnw8 , grocl-f0xsu8 , grocl-f0xtk0 , grocl-f0xtm0 , grocl-f0xv04 , grocl-f0x8s2 , grocl-f0xa18 , grocl-f0xm17 , grocl-f0x801 , grocl-f0xfy2