Stark H

References (22)

Title : 4-Oxypiperidine Ethers as Multiple Targeting Ligands at Histamine H(3) Receptors and Cholinesterases - Michalska_2024_ACS.Chem.Neurosci__
Author(s) : Michalska B , Dziegielewski M , Godyn J , Werner T , Bajda M , Karcz T , Szczepanska K , Stark H , Wieckowska A , Walczynski K , Staszewski M
Ref : ACS Chem Neurosci , : , 2024
PubMedID: 38440987

Title : Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer's disease - Hafez_2023_J.Enzyme.Inhib.Med.Chem_38_2175821
Author(s) : Hafez DE , Dubiel M , La Spada G , Catto M , Reiner-Link D , Syu YT , Abdel-Halim M , Hwang TL , Stark H , Abadi AH
Ref : J Enzyme Inhib Med Chem , 38 :2175821 , 2023
PubMedID: 36789662

Title : Guanidines: Synthesis of Novel Histamine H(3)R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect - Staszewski_2023_Pharmaceuticals.(Basel)_16_
Author(s) : Staszewski M , Iwan M , Werner T , Bajda M , Godyn J , Latacz G , Korga-Plewko A , Kubik J , Szalaj N , Stark H , Malawska B , Wieckowska A , Walczynski K
Ref : Pharmaceuticals (Basel) , 16 : , 2023
PubMedID: 37242458

Title : Multitargeting Histamine H(3) Receptor Ligands among Acetyl- and Propionyl-Phenoxyalkyl Derivatives - Lazewska_2023_Molecules_28_
Author(s) : Lazewska D , Kaleta M , Zareba P , Godyn J , Dubiel M , Honkisz-Orzechowska E , Doroz-Plonka A , Wieckowska A , Stark H , Kiec-Kononowicz K
Ref : Molecules , 28 : , 2023
PubMedID: 36903593

Title : Multitargeting approaches to cognitive impairment: Synthesis of aryl-alkylpiperazines and assessment at cholinesterases, histamine H(3) and dopamine D(3) receptors - Aranha_2022_Bioorg.Med.Chem_78_117132
Author(s) : Aranha C , Reiner-Link D , Leitzbach LR , Lopes FB , Stark H , Fernandes JPS
Ref : Bioorganic & Medicinal Chemistry , 78 :117132 , 2022
PubMedID: 36542960

Title : Evaluation of chromane derivatives: Promising privileged scaffolds for lead discovery within Alzheimer's disease - Moutayakine_2022_Bioorg.Med.Chem_68_116807
Author(s) : Moutayakine A , Marques C , Lopez O , Bagetta D , Leitzbach L , Hagenow S , Carreiro EP , Stark H , Alcaro S , Fernandez-Bolanos JG , Burke AJ
Ref : Bioorganic & Medicinal Chemistry , 68 :116807 , 2022
PubMedID: 35653868

Title : Benzophenone Derivatives with Histamine H(3) Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease - Godyn_2022_Molecules_28_
Author(s) : Godyn J , Zareba P , Stary D , Kaleta M , Kuder KJ , Latacz G , Mogilski S , Reiner-Link D , Frank A , Doroz-Plonka A , Olejarz-Maciej A , Sudol-Talaj S , Nolte T , Handzlik J , Stark H , Wieckowska A , Malawska B , Kiec-Kononowicz K , Lazewska D , Bajda M
Ref : Molecules , 28 : , 2022
PubMedID: 36615435

Title : Fatty Acid Synthase: Structure, Function, and Regulation - Gunenc_2022_Subcell.Biochem_99_1
Author(s) : Gunenc AN , Graf B , Stark H , Chari A
Ref : Subcell Biochem , 99 :1 , 2022
PubMedID: 36151372

Title : Repurposing of 8-Hydroxyquinoline-based Butyrylcholinesterase and Cathepsin B Ligands as Potent Non-peptidic Deoxyribonuclease I Inhibitors - Gajic_2022_ChemMedChem__
Author(s) : Gajic M , Knez D , Sosic I , Mravljak J , Meden A , Kosak U , Leitzbach L , George S , Hofmann B , Zivkovic A , Steinhilber D , Stark H , Gobec S , Smelcerovic A , Anderluh M
Ref : ChemMedChem , : , 2022
PubMedID: 34994078

Title : Biphenylalkoxyamine Derivatives-Histamine H(3) Receptor Ligands with Butyrylcholinesterase Inhibitory Activity - Lazewska_2021_Molecules_26_
Author(s) : Lazewska D , Zareba P , Godyn J , Doroz-Plonka A , Frank A , Reiner-Link D , Bajda M , Stary D , Mogilski S , Olejarz-Maciej A , Kaleta M , Stark H , Malawska B , Kiec-Kononowicz K
Ref : Molecules , 26 : , 2021
PubMedID: 34208297

Title : Ugi Reaction Synthesis of Oxindole-Lactam Hybrids as Selective Butyrylcholinesterase Inhibitors - Brandao_2021_ACS.Med.Chem.Lett_12_1718
Author(s) : Brandao P , Lopez O , Leitzbach L , Stark H , Fernandez-Bolanos JG , Burke AJ , Pineiro M
Ref : ACS Med Chem Lett , 12 :1718 , 2021
PubMedID: 34795859

Title : Cyanobiphenyls: Novel H(3) receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease - Godyn_2021_Bioorg.Chem_114_105129
Author(s) : Godyn J , Zareba P , aewska D , Stary D , Reiner-Link D , Frank A , Latacz G , Mogilski S , Kaleta M , Doroz-Plonka A , Lubelska A , Honkisz-Orzechowska E , Olejarz-Maciej A , Handzlik J , Stark H , Kiec-Kononowicz K , Malawska B , Bajda M
Ref : Bioorg Chem , 114 :105129 , 2021
PubMedID: 34217977

Title : Simultaneous Blockade of Histamine H(3) Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf\/J Mouse Model of Autism - Eissa_2020_Biomolecules_10_
Author(s) : Eissa N , Jayaprakash P , Stark H , Lazewska D , Kiec-Kononowicz K , Sadek B
Ref : Biomolecules , 10 : , 2020
PubMedID: 32872194

Title : The Dual-Active Histamine H3 Receptor Antagonist and Acetylcholine Esterase Inhibitor E100 Alleviates Autistic-Like Behaviors and Oxidative Stress in Valproic Acid Induced Autism in Mice - Eissa_2020_Int.J.Mol.Sci_21_
Author(s) : Eissa N , Azimullah S , Jayaprakash P , Jayaraj RL , Reiner D , Ojha SK , Beiram R , Stark H , Lazewska D , Kiec-Kononowicz K , Sadek B
Ref : Int J Mol Sci , 21 : , 2020
PubMedID: 32503208

Title : In silico and in vitro studies of two non-imidazole multiple targeting agents at histamine H3 receptors and cholinesterase enzymes - Ghamari_2020_Chem.Biol.Drug.Des_95_279
Author(s) : Ghamari N , Dastmalchi S , Zarei O , Arias-Montano JA , Reiner D , Ustun-Alkan F , Stark H , Hamzeh-Mivehroud M
Ref : Chemical Biology Drug Des , 95 :279 , 2020
PubMedID: 31661597

Title : Isoquinoline alkaloids from the roots of Zanthoxylum rigidum as multi-target inhibitors of cholinesterase, monoamine oxidase A and Abeta1-42 aggregation - Gonzalez_2020_Bioorg.Chem_98_103722
Author(s) : Gonzalez EP , Hagenow S , Murillo MA , Stark H , Suarez LC
Ref : Bioorg Chem , 98 :103722 , 2020
PubMedID: 32155491

Title : The dual-active histamine H3 receptor antagonist and acetylcholine esterase inhibitor E100 ameliorates stereotyped repetitive behavior and neuroinflammation in sodium valproate induced autism in mice - Eissa_2019_Chem.Biol.Interact__108775
Author(s) : Eissa N , Azimullah S , Jayaprakash P , Jayaraj RL , Reiner D , Ojha SK , Beiram R , Stark H , Lazewska D , Kiec-Kononowicz K , Sadek B
Ref : Chemico-Biological Interactions , :108775 , 2019
PubMedID: 31369746

Title : Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands - Bajda_2019_Eur.J.Med.Chem_185_111785
Author(s) : Bajda M , Lazewska D , Godyn J , Zareba P , Kuder K , Hagenow S , Latka K , Stawarska E , Stark H , Kiec-Kononowicz K , Malawska B
Ref : Eur Journal of Medicinal Chemistry , 185 :111785 , 2019
PubMedID: 31669851

Title : Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3 R Antagonism for Neurodegenerative Diseases - Bautista-Aguilera_2017_Angew.Chem.Int.Ed.Engl_56_12765
Author(s) : Bautista-Aguilera OM , Hagenow S , Palomino-Antolin A , Farre-Alins V , Ismaili L , Joffrin PL , Jimeno ML , Soukup O , Janockova J , Kalinowsky L , Proschak E , Iriepa I , Moraleda I , Schwed JS , Romero Martinez A , Lopez-Munoz F , Chioua M , Egea J , Ramsay RR , Marco-Contelles J , Stark H
Ref : Angew Chem Int Ed Engl , 56 :12765 , 2017
PubMedID: 28861918

Title : Predicting targets of compounds against neurological diseases using cheminformatic methodology - Nikolic_2015_J.Comput.Aided.Mol.Des_29_183
Author(s) : Nikolic K , Mavridis L , Bautista-Aguilera OM , Marco-Contelles J , Stark H , do Carmo Carreiras M , Rossi I , Massarelli P , Agbaba D , Ramsay RR , Mitchell JB
Ref : J Comput Aided Mol Des , 29 :183 , 2015
PubMedID: 25425329

Title : Exploring the chemical space of multitarget ligands using aligned self-organizing maps - Achenbach_2013_ACS.Med.Chem.Lett_4_1169
Author(s) : Achenbach J , Klingler FM , Blocher R , Moser D , Hafner AK , Rodl CB , Kretschmer S , Kruger B , Lohr F , Stark H , Hofmann B , Steinhilber D , Proschak E
Ref : ACS Med Chem Lett , 4 :1169 , 2013
PubMedID: 24900624

Title : Multiple enzyme inhibitions by histamine H3 receptor antagonists as potential procognitive agents - Petroianu_2006_Pharmazie_61_179
Author(s) : Petroianu GA , Arafat K , Sasse BC , Stark H
Ref : Pharmazie , 61 :179 , 2006
PubMedID: 16599255