Bajda M

References (49)

Title : 4-Oxypiperidine Ethers as Multiple Targeting Ligands at Histamine H(3) Receptors and Cholinesterases - Michalska_2024_ACS.Chem.Neurosci__
Author(s) : Michalska B , Dziegielewski M , Godyn J , Werner T , Bajda M , Karcz T , Szczepanska K , Stark H , Wieckowska A , Walczynski K , Staszewski M
Ref : ACS Chem Neurosci , : , 2024
PubMedID: 38440987

Title : Guanidines: Synthesis of Novel Histamine H(3)R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect - Staszewski_2023_Pharmaceuticals.(Basel)_16_
Author(s) : Staszewski M , Iwan M , Werner T , Bajda M , Godyn J , Latacz G , Korga-Plewko A , Kubik J , Szalaj N , Stark H , Malawska B , Wieckowska A , Walczynski K
Ref : Pharmaceuticals (Basel) , 16 : , 2023
PubMedID: 37242458

Title : Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, beta-secretase, and amyloid beta aggregation as potential treatment of Alzheimer's disease - Zareba_2023_Eur.J.Med.Chem_261_115832
Author(s) : Zareba P , Latka K , Mazur G , Gryzlo B , Pasieka A , Godyn J , Panek D , Skrzypczak-Wiercioch A , Hofner GC , Latacz G , Maj M , Espargaro A , Sabate R , Jozwiak K , Wanner KT , Salat K , Malawska B , Kulig K , Bajda M
Ref : Eur Journal of Medicinal Chemistry , 261 :115832 , 2023
PubMedID: 37837674

Title : New cyclopentaquinoline and 3,5-dichlorobenzoic acid hybrids with neuroprotection against oxidative stress for the treatment of Alzheimer's disease - Czarnecka_2023_J.Enzyme.Inhib.Med.Chem_38_2158822
Author(s) : Czarnecka K , Girek M , Krecisz P , Skibinski R , Latka K , Jonczyk J , Bajda M , Szymczyk P , Galita G , Kabzinski J , Majsterek I , Espargaro A , Sabate R , Szymanski P
Ref : J Enzyme Inhib Med Chem , 38 :2158822 , 2023
PubMedID: 36629422

Title : Benzophenone Derivatives with Histamine H(3) Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease - Godyn_2022_Molecules_28_
Author(s) : Godyn J , Zareba P , Stary D , Kaleta M , Kuder KJ , Latacz G , Mogilski S , Reiner-Link D , Frank A , Doroz-Plonka A , Olejarz-Maciej A , Sudol-Talaj S , Nolte T , Handzlik J , Stark H , Wieckowska A , Malawska B , Kiec-Kononowicz K , Lazewska D , Bajda M
Ref : Molecules , 28 : , 2022
PubMedID: 36615435

Title : Biphenylalkoxyamine Derivatives-Histamine H(3) Receptor Ligands with Butyrylcholinesterase Inhibitory Activity - Lazewska_2021_Molecules_26_
Author(s) : Lazewska D , Zareba P , Godyn J , Doroz-Plonka A , Frank A , Reiner-Link D , Bajda M , Stary D , Mogilski S , Olejarz-Maciej A , Kaleta M , Stark H , Malawska B , Kiec-Kononowicz K
Ref : Molecules , 26 : , 2021
PubMedID: 34208297

Title : Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase - Jonczyk_2021_Biomolecules_11_
Author(s) : Jonczyk J , Kukulowicz J , Aatka K , Malawska B , Jung YS , Musilek K , Bajda M
Ref : Biomolecules , 11 : , 2021
PubMedID: 33513955

Title : Biological evaluation and molecular docking of novel 1,3,4-thiadiazole-resorcinol conjugates as multifunctional cholinesterases inhibitors - Skrzypek_2021_Bioorg.Chem_107_104617
Author(s) : Skrzypek A , Matysiak J , Karpinska M , Czarnecka K , Krecisz P , Stary D , Kukulowicz J , Paw B , Bajda M , Szymanski P , Niewiadomy A
Ref : Bioorg Chem , 107 :104617 , 2021
PubMedID: 33444983

Title : Cyanobiphenyls: Novel H(3) receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease - Godyn_2021_Bioorg.Chem_114_105129
Author(s) : Godyn J , Zareba P , aewska D , Stary D , Reiner-Link D , Frank A , Latacz G , Mogilski S , Kaleta M , Doroz-Plonka A , Lubelska A , Honkisz-Orzechowska E , Olejarz-Maciej A , Handzlik J , Stark H , Kiec-Kononowicz K , Malawska B , Bajda M
Ref : Bioorg Chem , 114 :105129 , 2021
PubMedID: 34217977

Title : Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates - Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437
Author(s) : Lee HM , Andrys R , Jonczyk J , Kim K , Vishakantegowda AG , Malinak D , Skarka A , Schmidt M , Vaskova M , Latka K , Bajda M , Jung YS , Malawska B , Musilek K
Ref : J Enzyme Inhib Med Chem , 36 :437 , 2021
PubMedID: 33467931

Title : New Tetrahydroacridine Hybrids with Dichlorobenzoic Acid Moiety Demonstrating Multifunctional Potential for the Treatment of Alzheimer's Disease - Czarnecka_2020_Int.J.Mol.Sci_21_
Author(s) : Czarnecka K , Girek M , Wojtowicz P , Krecisz P , Skibinski R , Jonczyk J , Latka K , Bajda M , Walczak A , Galita G , Kabzinski J , Majsterek I , Szymczyk P , Szymanski P
Ref : Int J Mol Sci , 21 : , 2020
PubMedID: 32466601

Title : Multidirectional in vitro and in cellulo studies as a tool for identification of multi-target-directed ligands aiming at symptoms and causes of Alzheimer's disease - Szalaj_2020_J.Enzyme.Inhib.Med.Chem_35_1944
Author(s) : Szalaj N , Godyn J , Jonczyk J , Pasieka A , Panek D , Wichur T , Wieckowski K , Zareba P , Bajda M , Pislar A , Malawska B , Sabate R , Wieckowska A
Ref : J Enzyme Inhib Med Chem , 35 :1944 , 2020
PubMedID: 33092411

Title : Rational design of new multitarget histamine H(3) receptor ligands as potential candidates for treatment of Alzheimer's disease - Lazewska_2020_Eur.J.Med.Chem_207_112743
Author(s) : Lazewska D , Bajda M , Kaleta M , Zareba P , Doroz-Plonka A , Siwek A , Alachkar A , Mogilski S , Saad A , Kuder K , Olejarz-Maciej A , Godyn J , Stary D , Sudol S , Wiecek M , Latacz G , Walczak M , Handzlik J , Sadek B , Malawska B , Kiec-Kononowicz K
Ref : Eur Journal of Medicinal Chemistry , 207 :112743 , 2020
PubMedID: 32882609

Title : Synthesis, physicochemical and biological evaluation of tacrine derivative labeled with technetium-99m and gallium-68 as a prospective diagnostic tool for early diagnosis of Alzheimer's disease - Gniazdowska_2019_Bioorg.Chem_91_103136
Author(s) : Gniazdowska E , Kozminski P , Halik P , Bajda M , Czarnecka K , Mikiciuk-Olasik E , Maslowska K , Rogulski Z , Cheda L , Kilian K , Szymanski P
Ref : Bioorg Chem , 91 :103136 , 2019
PubMedID: 31374521

Title : Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands - Bajda_2019_Eur.J.Med.Chem_185_111785
Author(s) : Bajda M , Lazewska D , Godyn J , Zareba P , Kuder K , Hagenow S , Latka K , Stawarska E , Stark H , Kiec-Kononowicz K , Malawska B
Ref : Eur Journal of Medicinal Chemistry , 185 :111785 , 2019
PubMedID: 31669851

Title : Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives - Jonczyk_2019_Bioorg.Chem_90_103084
Author(s) : Jonczyk J , Lodarski K , Staszewski M , Godyn J , Zareba P , Soukup O , Janockova J , Korabecny J , Salat K , Malikowska-Racia N , Hebda M , Szalaj N , Filipek B , Walczynski K , Malawska B , Bajda M
Ref : Bioorg Chem , 90 :103084 , 2019
PubMedID: 31271942

Title : Discovery of New Cyclopentaquinoline Analogues as Multifunctional Agents for the Treatment of Alzheimer's Disease - Czarnecka_2019_Int.J.Mol.Sci_20_
Author(s) : Czarnecka K , Girek M , Krecisz P , Skibinski R , Latka K , Jonczyk J , Bajda M , Kabzinski J , Majsterek I , Szymczyk P , Szymanski P
Ref : Int J Mol Sci , 20 : , 2019
PubMedID: 30678364

Title : Biological Evaluation, Molecular Docking, and SAR Studies of Novel 2-(2,4-Dihydroxyphenyl)-1H- Benzimidazole Analogues - Matysiak_2019_Biomolecules_9_
Author(s) : Matysiak J , Skrzypek A , Karpinska M , Czarnecka K , Szymanski P , Bajda M , Niewiadomy A
Ref : Biomolecules , 9 : , 2019
PubMedID: 31842463

Title : Novel carbamate derivatives as selective butyrylcholinesterase inhibitors - Bajda_2018_Bioorg.Chem_78_29
Author(s) : Bajda M , Latka K , Hebda M , Jonczyk J , Malawska B
Ref : Bioorg Chem , 78 :29 , 2018
PubMedID: 29529519

Title : Design, Synthesis, and Biological Evaluation of 2-(Benzylamino-2-Hydroxyalkyl)Isoindoline-1,3-Diones Derivatives as Potential Disease-Modifying Multifunctional Anti-Alzheimer Agents - Panek_2018_Molecules_23_
Author(s) : Panek D , Wieckowska A , Pasieka A , Godyn J , Jonczyk J , Bajda M , Knez D , Gobec S , Malawska B
Ref : Molecules , 23 : , 2018
PubMedID: 29414887

Title : Tetrahydroacridine derivatives with dichloronicotinic acid moiety as attractive, multipotent agents for Alzheimer's disease treatment - Czarnecka_2018_Eur.J.Med.Chem_145_760
Author(s) : Czarnecka K , Chufarova N , Halczuk K , Maciejewska K , Girek M , Skibinski R , Jonczyk J , Bajda M , Kabzinski J , Majsterek I , Szymanski P
Ref : Eur Journal of Medicinal Chemistry , 145 :760 , 2018
PubMedID: 29353726

Title : Design, Synthesis, and Biological Evaluation of 1-Benzylamino-2-hydroxyalkyl Derivatives as New Potential Disease-Modifying Multifunctional Anti-Alzheimer's Agents - Panek_2018_ACS.Chem.Neurosci_9_1074
Author(s) : Panek D , Wieckowska A , Jonczyk J , Godyn J , Bajda M , Wichur T , Pasieka A , Knez D , Pislar A , Korabecny J , Soukup O , Sepsova V , Sabate R , Kos J , Gobec S , Malawska B
Ref : ACS Chem Neurosci , 9 :1074 , 2018
PubMedID: 29345897

Title : Tetrahydroacridine derivatives with fluorobenzoic acid moiety as multifunctional agents for Alzheimer's disease treatment - Czarnecka_2017_Bioorg.Chem_72_315
Author(s) : Czarnecka K , Szymanski P , Girek M , Mikiciuk-Olasik E , Skibinski R , Kabzinski J , Majsterek I , Malawska B , Jonczyk J , Bajda M
Ref : Bioorg Chem , 72 :315 , 2017
PubMedID: 28501648

Title : Synthesis, physicochemical and biological studies of technetium-99m labeled tacrine derivative as a diagnostic tool for evaluation of cholinesterase level - Gniazdowska_2017_Bioorg.Med.Chem_25_912
Author(s) : Gniazdowska E , Kozminski P , Wasek M , Bajda M , Sikora J , Mikiciuk-Olasik E , Szymanski P
Ref : Bioorganic & Medicinal Chemistry , 25 :912 , 2017
PubMedID: 27998671

Title : Lipophilic properties of anti-Alzheimer's agents determined by micellar electrokinetic chromatography and reversed-phase thin-layer chromatography - Godyn_2017_Electrophoresis_38_1268
Author(s) : Godyn J , Hebda M , Wieckowska A , Wieckowski K , Malawska B , Bajda M
Ref : Electrophoresis , 38 :1268 , 2017
PubMedID: 28169440

Title : New cyclopentaquinoline hybrids with multifunctional capacities for the treatment of Alzheimer's disease - Czarnecka_2017_J.Enzyme.Inhib.Med.Chem_33_158
Author(s) : Czarnecka K , Girek M , Maciejewska K , Skibinski R , Jonczyk J , Bajda M , Kabzinski J , Solowiej P , Majsterek I , Szymanski P
Ref : J Enzyme Inhib Med Chem , 33 :158 , 2017
PubMedID: 29210299

Title : Cholinesterase inhibitory activity of chlorophenoxy derivatives-Histamine H3 receptor ligands - Lazewska_2016_Bioorg.Med.Chem.Lett_26_4140
Author(s) : Lazewska D , Jonczyk J , Bajda M , Szalaj N , Wieckowska A , Panek D , Moore C , Kuder K , Malawska B , Kiec-Kononowicz K
Ref : Bioorganic & Medicinal Chemistry Lett , 26 :4140 , 2016
PubMedID: 27445168

Title : Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation - Panek_2016_Eur.J.Med.Chem_125_676
Author(s) : Panek D , Wieckowska A , Wichur T , Bajda M , Godyn J , Jonczyk J , Mika K , Janockova J , Soukup O , Knez D , Korabecny J , Gobec S , Malawska B
Ref : Eur Journal of Medicinal Chemistry , 125 :676 , 2016
PubMedID: 27721153

Title : Synthesis, Molecular Modelling and Biological Evaluation of Novel Heterodimeric, Multiple Ligands Targeting Cholinesterases and Amyloid Beta - Hebda_2016_Molecules_21_
Author(s) : Hebda M , Bajda M , Wieckowska A , Szalaj N , Pasieka A , Panek D , Godyn J , Wichur T , Knez D , Gobec S , Malawska B
Ref : Molecules , 21 : , 2016
PubMedID: 27023510

Title : Synthesis, biological evaluation and molecular modeling of new tetrahydroacridine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease - Bajda_2015_Bioorg.Med.Chem_23_5610
Author(s) : Bajda M , Jonczyk J , Malawska B , Czarnecka K , Girek M , Olszewska P , Sikora J , Mikiciuk-Olasik E , Skibinski R , Gumieniczek A , Szymanski P
Ref : Bioorganic & Medicinal Chemistry , 23 :5610 , 2015
PubMedID: 26242241

Title : Novel biphenyl bis-sulfonamides as acetyl and butyrylcholinesterase inhibitors: Synthesis, biological evaluation and molecular modeling studies - Mutahir_2015_Bioorg.Chem_64_13
Author(s) : Mutahir S , Jonczyk J , Bajda M , Khan IU , Khan MA , Ullah N , Ashraf M , Qurat Ul A , Riaz S , Hussain S , Yar M
Ref : Bioorg Chem , 64 :13 , 2015
PubMedID: 26595185

Title : Discovery of butyrylcholinesterase inhibitors among derivatives of azaphenothiazines - Lodarski_2015_J.Enzyme.Inhib.Med.Chem_30_98
Author(s) : Lodarski K , Jonczyk J , Guzior N , Bajda M , Gladysz J , Walczyk J , Jelen M , Morak-Mlodawska B , Pluta K , Malawska B
Ref : J Enzyme Inhib Med Chem , 30 :98 , 2015
PubMedID: 24666296

Title : Pyridine sulfonamide as a small key organic molecule for the potential treatment of type-II diabetes mellitus and Alzheimer's disease: In vitro studies against yeast alpha-glucosidase, acetylcholinesterase and butyrylcholinesterase - Riaz_2015_Bioorg.Chem_63_64
Author(s) : Riaz S , Khan IU , Bajda M , Ashraf M , Qurat Ul A , Shaukat A , Rehman TU , Mutahir S , Hussain S , Mustafa G , Yar M
Ref : Bioorg Chem , 63 :64 , 2015
PubMedID: 26451651

Title : Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with beta-amyloid anti-aggregation properties and beneficial effects on memory in vivo - Wieckowska_2015_Bioorg.Med.Chem_23_2445
Author(s) : Wieckowska A , Wieckowski K , Bajda M , Brus B , Salat K , Czerwinska P , Gobec S , Filipek B , Malawska B
Ref : Bioorganic & Medicinal Chemistry , 23 :2445 , 2015
PubMedID: 25868744

Title : Development of multifunctional, heterodimeric isoindoline-1,3-dione derivatives as cholinesterase and beta-amyloid aggregation inhibitors with neuroprotective properties - Guzior_2015_Eur.J.Med.Chem_92C_738
Author(s) : Guzior N , Bajda M , Skrok M , Kurpiewska K , Lewinski K , Brus B , Pislar A , Kos J , Gobec S , Malawska B
Ref : Eur Journal of Medicinal Chemistry , 92C :738 , 2015
PubMedID: 25621991

Title : Multiple Ligands Targeting Cholinesterases and beta-Amyloid: Synthesis, Biological Evaluation of Heterodimeric Compounds with Benzylamine Pharmacophore - Szalaj_2015_Arch.Pharm.(Weinheim)_348_556
Author(s) : Szalaj N , Bajda M , Dudek K , Brus B , Gobec S , Malawska B
Ref : Arch Pharm (Weinheim) , 348 :556 , 2015
PubMedID: 26032855

Title : Isoindoline-1,3-dione derivatives targeting cholinesterases: Design, synthesis and biological evaluation of potential anti-Alzheimer's agents - Guzior_2015_Bioorg.Med.Chem_23_1629
Author(s) : Guzior N , Bajda M , Rakoczy J , Brus B , Gobec S , Malawska B
Ref : Bioorganic & Medicinal Chemistry , 23 :1629 , 2015
PubMedID: 25707322

Title : SEARCH FOR POTENTIAL CHOLINESTERASE INHIBITORS FROM THE ZINC DATABASE BY VIRTUAL SCREENING METHOD - Bajda_2015_Acta.Pol.Pharm_72_737
Author(s) : Bajda M , Panek D , Hebda M , Wieckowska A , Guzior N , Malawska B
Ref : Acta Pol Pharm , 72 :737 , 2015
PubMedID: 26647631

Title : Design and Synthesis of New Dual Binding Site Cholinesterase Inhibitors: Inhibition Studies with Docking - Yar_2014_Lett.Drug.Des.Discov_11_331
Author(s) : Yar M , Bajda M , Mehmood RA , Sidra LR , Ullah N , Shahzadi L , Ashraf M , Ismail T , Shahzad SA , Khan ZA , Naqvi SA , Mahmood N
Ref : Lett Drug Des Discov , 11 :331 , 2014
PubMedID: 24719609

Title : Synthesis and biological evaluation of 1,3,4-thiadiazole analogues as novel AChE and BCHE inhibitors - Skrzypek_2013_Eur.J.Med.Chem_62C_311
Author(s) : Skrzypek A , Matysiak J , Niewiadomy A , Bajda M , Szymanski P
Ref : Eur Journal of Medicinal Chemistry , 62C :311 , 2013
PubMedID: 23376249

Title : New tacrine analogs as acetylcholinesterase inhibitors - theoretical study with chemometric analysis - Szymanski_2013_Molecules_18_2878
Author(s) : Szymanski P , Skibinski R , Inglot T , Bajda M , Jonczyk J , Malawska B , Mikiciuk-Olasik E
Ref : Molecules , 18 :2878 , 2013
PubMedID: 23459299

Title : Structure-based search for new inhibitors of cholinesterases - Bajda_2013_Int.J.Mol.Sci_14_5608
Author(s) : Bajda M , Wieckowska A , Hebda M , Guzior N , Sotriffer CA , Malawska B
Ref : Int J Mol Sci , 14 :5608 , 2013
PubMedID: 23478436

Title : Design, synthesis and evaluation of novel 2-(aminoalkyl)-isoindoline-1,3-dione derivatives as dual-binding site acetylcholinesterase inhibitors - Ignasik_2012_Arch.Pharm.(Weinheim)_345_509
Author(s) : Ignasik M , Bajda M , Guzior N , Prinz M , Holzgrabe U , Malawska B
Ref : Arch Pharm (Weinheim) , 345 :509 , 2012
PubMedID: 22467516

Title : Synthesis, biological activity and molecular modeling of 4-fluoro-N-[omega-(1,2,3,4-tetrahydroacridin-9-ylamino)-alkyl]-benzamide derivatives as cholinesterase inhibitors - Szymanski_2012_Arzneimittelforschung_62_655
Author(s) : Szymanski P , Markowicz M , Bajda M , Malawska B , Mikiciuk-Olasik E
Ref : Arzneimittelforschung , 62 :655 , 2012
PubMedID: 23154886

Title : 2,3-dihydro-1H-cyclopenta[b]quinoline derivatives as acetylcholinesterase inhibitors-synthesis, radiolabeling and biodistribution - Szymanski_2012_Int.J.Mol.Sci_13_10067
Author(s) : Szymanski P , Laznickova A , Laznicek M , Bajda M , Malawska B , Markowicz M , Mikiciuk-Olasik E
Ref : Int J Mol Sci , 13 :10067 , 2012
PubMedID: 22949848

Title : Multi-target-directed ligands in Alzheimer's disease treatment - Bajda_2011_Curr.Med.Chem_18_4949
Author(s) : Bajda M , Guzior N , Ignasik M , Malawska B
Ref : Curr Med Chem , 18 :4949 , 2011
PubMedID: 22050745

Title : Novel alkyl- and arylcarbamate derivatives with N-benzylpiperidine and N-benzylpiperazine moieties as cholinesterases inhibitors - Wieckowska_2010_Eur.J.Med.Chem_45_5602
Author(s) : Wieckowska A , Bajda M , Guzior N , Malawska B
Ref : Eur Journal of Medicinal Chemistry , 45 :5602 , 2010
PubMedID: 20926161

Title : Electrophoretically mediated microanalysis technique as a tool for the rapid screening of novel acetylcholinesterase inhibitors - Bajda_2009_Acta.Pol.Pharm_66_357
Author(s) : Bajda M , Wieckowska A , Malawska B
Ref : Acta Pol Pharm , 66 :357 , 2009
PubMedID: 19702166

Title : Recent developments in cholinesterases inhibitors for Alzheimer's disease treatment - Musial_2007_Curr.Med.Chem_14_2654
Author(s) : Musial A , Bajda M , Malawska B
Ref : Curr Med Chem , 14 :2654 , 2007
PubMedID: 17979717