geost-lipas

Bacillus stearothermophilus Geobacillus stearothermophilus EH97 lipase gene, complete cds

Comment

EH97 promiscuous activity 11\/96 substrates Martinez-Martinez et al. 2018 || \; Sinchaikul sequence is from Bacillus stearothermophilus strain P1 (trembl Q9L6D3) and Kim from strain L1 (trembl O66015) some differences in sequences also between the two structure 1KUO and 1JI3

Relationship

Family : Bacterial_lip_FamI.5

Block : L

Position in NCBI Life Tree : Geobacillus stearothermophilus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Firmicutes N E > Bacilli N E > Bacillales N E > Bacillaceae N E > Geobacillus N E > Geobacillus stearothermophilus N E

Molecular evidence

No mutation

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MMKGCRVMVV LLGLWFVFGL SVPGGRTEAA SPRANDAPIV LLHGFTGWGR EEMLGFKYWG GVRGDIEQWL NDNGYRTYTL AVGPLSSNWD RACEAYAQLV GGTVDYGAAH AANDGHARFG RTYPGLLPEL KRGGRVHIIA HSQGGQTARM LVSLLENGSQ EEREYAKEHN VSLSPLFEGG HRFVLSVTTI ATPHDGTTLV NMVDFTDRFF DLQKAVLEAA AVASNAPYTS EIYDFKLDQW GLRREPGESF DHYFERLKRS PVWTSTDTAR YDLSVPGAET LNRWVKASPN TYYLSFSTER TYRGALTGNY YPELGMNAFS AIVCAPFLGS YRNAALGIDS HWLGNDGIVN TISMNGPKRG SNDRIVPYDG TLKKGVWNDM GTYKVDHLEV IGVDPNPSFN IRAFYLRLAE QLASLRP

References (9)

Title : Determinants and prediction of esterase substrate promiscuity patterns - Martinez-Martinez_2018_ACS.Chem.Biol_13_225
Author(s) : Martinez-Martinez M , Coscolin C , Santiago G , Chow J , Stogios PJ , Bargiela R , Gertler C , Navarro-Fernandez J , Bollinger A , Thies S , Mendez-Garcia C , Popovic A , Brown G , Chernikova TN , Garcia-Moyano A , Bjergah GE , Perez-Garcia P , Hai T , Del Pozo MV , Stokke R , Steen IH , Cui H , Xu X , Nocek BP , Alcaide M , Distaso M , Mesa V , Pelaez AI , Sanchez J , Buchholz PCF , Pleiss J , Fernandez-Guerra A , Glockner FO , Golyshina OV , Yakimov MM , Savchenko A , Jaeger KE , Yakunin AF , Streit WR , Golyshin PN , Guallar V , Ferrer M
Ref : ACS Chemical Biology , 13 :225 , 2018
Abstract :
PubMedSearch : Martinez-Martinez_2018_ACS.Chem.Biol_13_225
PubMedID: 29182315
Gene_locus related to this paper: 9zzzz-a0a2k8jn75 , 9zzzz-a0a2k8jt94 , 9zzzz-a0a0g3fj44 , 9zzzz-a0a0g3fh10 , 9zzzz-a0a0g3fh03 , 9bact-a0a1s5qkj8 , 9zzzz-a0a0g3feh5 , 9zzzz-a0a0g3fkz4 , 9zzzz-a0a0g3fh07 , 9zzzz-a0a0g3fh34 , 9zzzz-a0a0g3fh31 , 9bact-KY458167 , alcbs-q0vqa3 , 9bact-a0a1s5qki8 , 9zzzz-a0a0g3feq8 , 9zzzz-a0a0g3feh8 , 9zzzz-a0a0g3fh19 , 9bact-KY203037 , 9bact-a0a1s5ql22 , 9bact-a0a1s5qm34 , 9bact-KY203034 , 9bact-r9qzg0 , 9bact-a0a1s5qly8 , 9zzzz-a0a0g3fkz8 , 9zzzz-a0a0g3feg9 , 9zzzz-KY203033 , 9zzzz-a0a0g3fes4 , 9zzzz-a0a0g3fh42 , 9bact-a0a1s5qlx2 , 9zzzz-KY483651 , 9bact-a0a1s5qmh4 , 9zzzz-KY203032 , 9zzzz-EH87 , 9zzzz-a0a0g3fei1 , 9zzzz-a0a0g3fet2 , 9zzzz-KY483647 , 9zzzz-EH82 , 9zzzz-a0a0g3fe15 , 9bact-KY203031 , 9bact-t1w006 , 9zzzz-a0a0g3fet6 , 9bact-KY458164 , geoth-g8myf3 , 9bact-a0a1s5ql04 , 9gamm-a0a1y0ihk7 , 9bact-a0a1s5qly6 , 9bact-a0a1s5qkg4 , 9bact-a0a1s5qkm4 , 9gamm-s5tv80 , 9gamm-a0a0c4zhg2 , 9zzzz-t1b379 , 9gamm-KY483646 , 9bact-KY458160 , 9zzzz-a0a0g3fj57 , 9gamm-s5t8349 , 9arch-KY203036 , 9bact-KY458168 , 9zzzz-a0a0g3fes0 , 9zzzz-t1be47 , 9bact-KY458159 , 9zzzz-a0a0g3fh39 , 9bact-t1vzd5 , 9prot-EH41 , 9bact-Lip114 , alcbs-q0vt77 , 9bact-a0a1s5qke6 , 9bact-a0a1s5qkf3 , 9prot-SRP030024 , 9gamm-s5t532 , 9bact-a0a1s5qkl2 , 9bact-a0a1s5qkk8 , 9zzzz-KY203030 , 9zzzz-t1d4I7 , 9prot-KY019260 , 9bact-a0a1s5qm38 , 9arch-KY458161 , 9prot-KY010302 , 9zzzz-a0a0g3fl25 , 9actn-KY010298 , 9gamm-s5u059 , 9bact-a0a1s5qmi7 , 9bact-KY010297 , 9bact-KY483642 , 9bact-a0a1s5qkj1 , 9bact-KY010299 , 9bact-KY483648 , alcbs-q0vtl7 , 9bact-a0a1s5qf1 , 9bact-a0a1s5qkg0 , 9bact-a0a0h4tgu6 , 9bact-MilE3 , 9bact-LAE6 , 9alte-MGS-MT1 , 9bact-r9qzf7 , 9gamm-k0c6t6 , alcbs-q0vl36 , alcbs-q0vlq1 , alcbs-q0vq49 , bacsu-pnbae , canar-LipB , canan-lipasA , geost-lipas , marav-a1u5n0 , pseps-i7k8x5 , staep-GEHD , symth-q67mr3 , altma-s5cfn7 , cycsp-k0c2b8 , alcbs-q0vlk5 , 9bact-k7qe48 , 9bact-MGS-M1 , 9bact-MGS-M2 , 9bact-a0a0b5kns5 , 9zzzz-a0a0g3fej4 , 9zzzz-a0a0g3fj60 , 9zzzz-a0a0g3fej0 , 9zzzz-a0a0g3fj64 , 9bact-a0a0b5kc16 , 9zzzz-a0a0g3feg6 , 9zzzz-a0a0g3feu6

Title : Molecular dynamics study of the structure, flexibility and dynamics of thermostable l1 lipase at high temperatures - Abedi_2009_Protein.J_28_14
Author(s) : Abedi Karjiban R , Abdul Rahman MB , Basri M , Salleh AB , Jacobs D , Abdul Wahab H
Ref : Protein J , 28 :14 , 2009
Abstract :
PubMedSearch : Abedi_2009_Protein.J_28_14
PubMedID: 19130194
Gene_locus related to this paper: geost-lipas

Title : Zinc in lipase L1 from Geobacillus stearothermophilus L1 and structural implications on thermal stability - Choi_2005_FEBS.Lett_579_3461
Author(s) : Choi WC , Kim MH , Ro HS , Ryu SR , Oh TK , Lee JK
Ref : FEBS Letters , 579 :3461 , 2005
Abstract :
PubMedSearch : Choi_2005_FEBS.Lett_579_3461
PubMedID: 15949807
Gene_locus related to this paper: geost-lipas

Title : Expression, purification, crystallization and preliminary crystallographic analysis of a thermostable lipase from Bacillus stearothermophilus P1 - Sinchaikul_2002_Acta.Crystallogr.D.Biol.Crystallogr_58_182
Author(s) : Sinchaikul S , Tyndall JD , Fothergill-Gilmore LA , Taylor P , Phutrakul S , Chen ST , Walkinshaw MD
Ref : Acta Crystallographica D Biol Crystallogr , 58 :182 , 2002
Abstract :
PubMedSearch : Sinchaikul_2002_Acta.Crystallogr.D.Biol.Crystallogr_58_182
PubMedID: 11752807
Gene_locus related to this paper: geost-lipas

Title : Novel zinc-binding center and a temperature switch in the Bacillus stearothermophilus L1 lipase - Jeong_2002_J.Biol.Chem_277_17041
Author(s) : Jeong ST , Kim HK , Kim SJ , Chi SW , Pan JG , Oh TK , Ryu SE
Ref : Journal of Biological Chemistry , 277 :17041 , 2002
Abstract :
PubMedSearch : Jeong_2002_J.Biol.Chem_277_17041
PubMedID: 11859083
Gene_locus related to this paper: geost-lipas

Title : Crystal Structure of a Thermostable Lipase from Bacillus stearothermophilus P1 - Tyndall_2002_J.Mol.Biol_323_859
Author(s) : Tyndall JD , Sinchaikul S , Fothergill-Gilmore LA , Taylor P , Walkinshaw MD
Ref : Journal of Molecular Biology , 323 :859 , 2002
Abstract :
PubMedSearch : Tyndall_2002_J.Mol.Biol_323_859
PubMedID: 12417199
Gene_locus related to this paper: geost-lipas

Title : Structural modeling and characterization of a thermostable lipase from Bacillus stearothermophilus P1 - Sinchaikul_2001_Biochem.Biophys.Res.Commun_283_868
Author(s) : Sinchaikul S , Sookkheo B , Phutrakul S , Wu YT , Pan FM , Chen ST
Ref : Biochemical & Biophysical Research Communications , 283 :868 , 2001
Abstract :
PubMedSearch : Sinchaikul_2001_Biochem.Biophys.Res.Commun_283_868
PubMedID: 11350065
Gene_locus related to this paper: geost-lipas

Title : Optimization of a thermostable lipase from Bacillus stearothermophilus P1: overexpression, purification, and characterization - Sinchaikul_2001_Protein.Expr.Purif_22_388
Author(s) : Sinchaikul S , Sookkheo B , Phutrakul S , Pan FM , Chen ST
Ref : Protein Expr Purif , 22 :388 , 2001
Abstract :
PubMedSearch : Sinchaikul_2001_Protein.Expr.Purif_22_388
PubMedID: 11483000
Gene_locus related to this paper: geost-lipas

Title : Gene cloning and characterization of thermostable lipase from Bacillus stearothermophilus L1 - Kim_1998_Biosci.Biotechnol.Biochem_62_66
Author(s) : Kim HK , Park SY , Lee JK , Oh TK
Ref : Biosci Biotechnol Biochem , 62 :66 , 1998
Abstract :
PubMedSearch : Kim_1998_Biosci.Biotechnol.Biochem_62_66
PubMedID: 9501519
Gene_locus related to this paper: geost-lipas